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# Borrelia afzelii, PKo

>BAPKO_0448 hypothetical protein
MKIYLASPFFNEEQIKLRDEVLKFLEEFNLDVFSPEHHAVKKMGLLEKVD
YKFVNRDIREKIREIDLKELVSSDIVLALVNYVDAGTAYERGFAFAKKIP
SIDFFKDKQDSDFYNLMYSDCNASFTNYSDLREGILTFKELWIKFKGDNE
NFRTFFDYLKAKLGNKLKKVLTTLPVNEKCGC
>BAPKO_0767 adenylyl cyclase, CyaB-type, putative
MFEIESKAFIPPKELKRIIKLANKKFKFIKEEIKTDIYYSNPKKIIRIRK
LNTLEKIVTFKKKILDKNNAIEINKEVEFKIDNVNNFLILLKELKFKKLY
KKIKKSLIYQTNNLNVEINEVKNLGFFLEIEKIINNQNDIDLAKKEINNI
INQFGLKENLETRSYFELLSSTNQSKK
>BAPKO_3026 hypothetical protein
MKIKNITNPLIIFLSIVLNIWGNEPKINESDENSQSNILIISATKAEIAE
IDKIIQNKKSISIEEHRRKKKITIGKVLNHNIITIATGVGKINTAFWTSY
IISKYKISHIINAGVASGIYSNKNKFVKVGDVIISTETTNYDFNLHRFGY
EIGHIPEHPKKFKANTALIRKVSKIKIKNTTSYLGLIITGDQFIDHQNFQ
EIPEEFENAIAIDMESAAMAQVAYNFKIPFIIIRGISDIVNNENNYDDYK
KFLKKASSNSAKIVENLIKLM
>BAPKO_0256 conserved hypothetical protein
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLK
AKALFEILNKNQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNE
KNQLILDLMKNEKNRHAYFICNISYISKNRQISNFEGIIKGKIALSLNDD
KNHGFGYDSIFLTKNNKKLSDLTLEEKNKISHRGIAFSKFKKFLLESLFN
S
>BAPKO_0872 conserved hypothetical protein
MKIALSGKSGCGNTTVSSMIAKHYGLEFINYTFHDIARERNIPFSEFYEK
EIIGRDDYYWDRYLDKRLFALSKKNNTVLASRLAIWISKSADLKIYLYAK
MEVRAERIMTREGGMYSDVLSSTFNRDENDKKRYLAIYNIDIDDYSSETD
LVIDVTNINSNEVFELIRDEIDKRNLKN
>BAPKO_3002 hypothetical protein
MLIHSGLILTGDQFIDPIYIKKILKNFKDVIAVEMEGAAVGHVSHIFNVP
FIVIRSICDIVNKEKNEVEYNKFFELAAFNSAKVVQEILRIL
>BAPKO_3033 hypothetical protein
MNLFKIKANYIDIFNKEIYPASITIENGYIVSIEKIDATLDEYVLPGFID
AHIHIESSFLIPSNFAHLVVQHGTVATISDPHEIANVNGIDGINFMINNS
KKTEFKIFFGAPSCVPALSSKFETSGHVLDDQDVDKLMESNDIYYLSEVM
DFKGVINKDVEVINKINSALKRNKVVDGHAPGLSPHLTLKYMSSGISTDH
ECSTIEDARYKLSLGVKIIIREGSAAKNFESLHPLISECSNKYCDSLMFC
FDDAHPNDILHGHINSIVARAIGYGHDFFDVLKIACINPVLHYKIPVGLL
RIGDPADFIITKDIKTFKIDKTYINGKLVYSDGISHIPLISEIPINNFNC
SEKSILDFKFSTKNKMIPIINCINNQIITQKTMIDSNLLAPDFQSNIAED
ILKIAIINRYEDNSKISIGFIKNFGIRKGAIGSTVAHDSHNIIVVGTNDE
YLCKATNIIIENKGGLCALNNEKTIIIKLPISGLMSTLPAKEIAFQYMKL
NDFCKNILGSQLDDPLMTLSFMSLTVVPHLKINDKGLFDVDSFCFLDY
>BAPKO_3003 hypothetical protein
MDYELEQINKLMSNKEEIVLKEYGLNKKIVKGKLSNRNVMVVDCGVGKVN
IGAWMGYILSKYKISHIINSGVAGGVVSDKYKNIKVGDVVVSSEVAYHDV
DLTKFGHKVGQLMGFPQKFSADKNLIKKAREAIKLKVGDANTFRININRR
SVY
>BAPKO_0433 adk, adenylate kinase
MELVFLGPPGSGKGTISKIISNEFQYYHISTGDLFRENILNSTTLGKEIK
KIVEKGELVPDLITIKIVEDKIKSIKKNKNFILDGFPRNICQAKALDKFL
PNVKIINFLIDEESVIKRLSGRRICKSCNNIFNIHTLATKNIGICDVCGG
DLYQREDDKEECLKTRLKEYKLQTKPLIEFYSKCSRINNVDASVTIDEVR
KKIIKIMLKKN
>BAPKO_0826 apt, adenine phosphoribosyltransferase
MKNKTEYYDQFIAKVPNFPKKGILFYDITSVLLKPEVYTSLINEVYSFYN
LKKIDCIAVVESRGYLIGAPLSLKMQLPLVLIRKEGKLPREVFGEEYELE
YGFGRIEVHKDDVRMYSNILLIDDILATGGTLKSSAILLERAGGRVKNIF
CFIELCGINGRRILEGYKVNSLVRYD
>BAPKO_0656 cdd, cytidine deaminase
MKKPKQEDIDKAFYMAEKARNNSYSPYSKFKVGVCIKTKTNEFFIGTNVE
NASFGATCCAERSAISNMIAKIGVQTIDFLLLNTSPEAIPCAICLQVMAE
FFDQDTKIIITESKSFNENKMPTKIYTLKDLLKVPFDRKELHRVTQ
>BAPKO_0130 cmk, cytidylate kinase
MIIAIDGPSASGKSSIARELSVKLGFKFISSGYLYRIITLIAQRSFISGC
DFISENRLLNLVLENDISFNDSSFLLNGENVENQILNDKIDFQVSFYSSY
IGIRNIVNKKLREVVKFSDDNYIIEGRDITTIVFPESEFKIYLDASIKVR
ALRRYKQRNGNETLEELERTLKIRDDVDKNKQYGKLELSKGVFYLDTSYK
GLDDVCNIIIEKFNLKKVRER
>BAPKO_0248 dck, deoxyguanosine/deoxyadenosine kinase(I) subunit 2
MIVIEGLIGVGKTTLGNILSKELKVPFYSELNNDFTLAVLDKFYKDKSRW
AFPVQINFLNERFKLIKGVFRTKGGILDRSIYGDCVFASLLNCDGHISDE
EYKIYIDLLDNMLEHSQRPSLLIYLDCSIDEVERRIKNRNRSFEMNIPRD
YLEGLNKKYLKWYNEYSLSSKIKFSYDNINIFDEEDKNKVISLIRDKLVL
>BAPKO_5017 guaA, GMP synthase
MNARAILILDFGSQYSQLIARRIREIGVYTKVIPYCTPLKEIENMNIAGI
ILSGGPASVYLKDAPTLNMEIFNLKIPVLGICYGMQLIVKLFGGLVSKDC
KQEYGGSELFLKNEKSLLFSELPNKFQIIMSHGDSIEKIPNNFKQLAFTK
NCIASISDETQKIYGLQFHPEVTHSEFGDQILKNFVFKICQAQTNWSLEG
NIETIVEKIKLKVGSKKVILGLSGGTDSLVCALLIKKAIKGNLICVFVNT
GLLRKNEDKKILELKQQYDLNIQYIDASEKFLNHLKNISDPEEKRKIIGK
EFVNVFEKITLGDQNIEYLAQGTIYSDVIESKSKNNASSKIKSHHNVGGL
PDKMSLKLLEPLNEFFKDEIIQIGINLGIKKEDLYRHPFPGPGLAIRIIG
EITQEKINILQEADNILIEELFINDLYYEIRQAFVVLLPVKSVGVMGDQR
TYEYTAVIRCVNTQDFMTAEWTELPYNFLKKVSSRIINEVRGINRVCYDI
SSKPPSTIEWE
>BAPKO_5016 guaB, IMP dehydrogenase
MTNKIIKEALTFDDVSLIPRKSSILPSEVSLKTQLTKNISLNIPFLSSAM
DTVTESQMAIAIAKEGGIGIIHKNMSIEAQKKEIEKVKTYKAQKTINTNK
VTNEQETKMLTKQYLEEPEIHKNTEHKEDFSNACKDLNSKLRVGAAISID
IDTIERVEELVKAHVDLIVIDSAHGHSTRIIELVKTIKNKYPNLDLIAGN
IVTKEAALDLINAGADCLKVGIGPGSICTTRIVAGVGVPQITAICDVYEV
CKNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGAKESPSEEIIY
NGKKFKSYVGMGSISAMKRGSKSRYFQLENNEPKKLVPEGIEGMVPYSGE
LKDILNQLKGGLMSGMGYLGAITISDLKINSKFVKISHSSLKESHPHDVF
KMP
>BAPKO_0492 ndk, nucleoside-diphosphate kinase
MSMLLQKTLCIIKPDGVRRGLIGDIVARFERVGLKMVAAKMLIVDENLAK
KHYLYDDIALRHSEAVWRSLVKFISNSPVFVFVVEGVESIEVVRKLCGAT
EPKLAIPGTIRGDFSYHSLKYSNEKGFSIYNVIHASANEVDAIREISIWF
KDNEILNYKRDDECEHYYC
>BAPKO_0427 nucA, endonuclease precursor
MKKRSKFFLYCYILCLAGFLFFSLNPKILKQIKNRIYDYLEILENKYINI
TKSIPIKESQLIPKGYLTTQIIRKKHYTLGYAESARQSEWAAYPLKREMV
ELALTLLKSKKIKRSTKFFEDTNLKGTFPKLEDYFKSGYDRGHIVNSADM
SFSETAMKDTYFLSNMSPQKSEFNSGIWLKLEKLVREWAISKGYIYIISA
GILTENKGFIGKNKILVPKNFYKIVLAINNNNSFDIISFIIPNEKAKDLD
LKNYVVNVDSIEKKTKIDFFEKLDSKIKKNIKKIKNIHSWKFK
>BAPKO_0384 pfs-1, 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative
MILIISAMQEESEEINKMIDDKEEVILNDYLENKKFYKGKILGKDVISLT
TGIGKVNAATWSNQIISKYKITHIINSGSSGGIKENSNLKISDIIVSSQA
AYYDFDLTKFGHKIGQVPNLPQKFKADEELLKKVVNIIDNKLLNIDIHIG
LILTGDQFVDNEKNLEAIKKNFKDALAVDMEGAAIAQVAHMFKIPFIIIR
SISDLPNNKDNHIDFNKFLKTSSINSSKMTKELIRLI
>BAPKO_0619 pfs-2, 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative
MNNFLIKLLLFLLVFSNSYVAFSKNSNVLIITAMDSEVEQINKLMSNKEE
IVLKEYGLNKKILKGKLSNRNVITIVCGVGKVNAGVWTSYILSKYNISHV
INSGVAGGVVSDKYKDIKVGDVVVSSEVAYHDVDLTKFGHKVGQLMGLPQ
KFSANKNLVDKATKAVKSKVASSNSYSGLILSGDQFIDPAYINKIIGNFK
DVIAVEMEGAAVGHVSHMFNVPFIVIRSISDIVNKEGNELEYSKFLKLAA
FNSAKVVQEILRIL
>BAPKO_0388 pkcI, protein kinase C1 inhibitor
MYDCIFCKIVNKELPSYKVYEDDLVLAFLDINPLTVGHTLVIPKEHSENL
LNMDDKFNDRVLGVCKKISNALKKINSSICVGVNIYSSLGAGAGQEVFHT
HFHVIPRFKNDGFGFKRGNKLNLEVNKFKELSMQISMNI
>BAPKO_0573 prs, phosphoribosyl pyrophosphate synthetase
MNLLKKKSIGIIACPGGRVFANKIIEELEKIFINVENDIVDSICRDSKVL
KEEIFKLEKVLSPFLEGLSLSTLKCKEPLEIPVKFVKFANGEFKTEILKT
IRNKDIFIVQDVANTYEVEINSNEKVIMTVNDHIMNLMTTIDACMQAKAS
SVSVIIPSYPYSRQDKKHSRECLTASLIGRFLEELGIRHILTLDIHSKAI
ENVFRKVYFENLNVSYEIFKSLRDLIDIRDSNLVIVSPDTGAVSRNKFFA
STLKSPLALLYKERDYSRVSSDITDSNISVTKLLGDVEGKNVFMSDDMLA
TGGTLIKAMKLLKSMGAKKIICGISLPFFNGDAIKYFDKAYEEGYFYKII
GTNAVCHNDELINKPWYYEANVAHLFANAIFAIYNKVGLQKILDRRDDIQ
KLITKG
>BAPKO_0606 pyrG, CTP synthase
MKKNLKILVITGGVISGIGKGVTSASIARLFRYDFRVTPIKCDGYLNTDP
GTINPVEHGEVFVLDDGGEVDMDFGHYERFLNLNAKSSWNITMGKIYKKI
LENERKGKYLGRTVQLIPHVTDEIKSTIFQIASSENSEMLIIEIGGTVGD
MENILFIETVRQIRHEVGSGNIAFIHLTYVPSPVGINEQKSKPTQQSVKT
LNKAGIFPDLIIARSSQVLTDQIRKKIAMFCNVESTSIIDNIDVSTIYEI
PISFYKQGVHEILSSKLNIKVDPKIEELSRLVGIIKSNFFVPKKIINIAI
CGKYAELDDSYASIRESLVHVAANLDLLIKSTLIDSNDLNESCLKDFDGI
IVPGGFGGKGYEGKIIAIKYARENNIPFLGICLGLQLAVIEFARNVCGIL
DADTEENLIKDKPLKNPVIHLLPEQKEIKDKGATMRLGGYPVILKKNTIA
FKLYGQDRIIERFRHRYEVNNDYIDLFEKNGLIVSGFSSDFKIAKLIEIP
KNKFFVACQFHPELITRIENPAKLFLGLIKACI
>BAPKO_0602 smbA, uridylate kinase
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGKV
AREYQDAYKKINPNFKVSELDEIGIMSTKLNAEFLCKVMNPLCKDKIVTN
PLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDIINITNVNQVYD
KDPKKFKNATAFKKLNWEQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLT
LYIVNGNNIENLEKVFNKNNDFLGTVIVK
>BAPKO_0843 tdk, thymidine kinase
MGFCLDFANKEDAKLNNIVSISHFDFKVKINLILVVGPMGSGKTEYAAKI
YKDSLVVRKKSFKVLGNIIKGNRSRVNVFFIRNFLDKRRFQDFPENVIPY
RGGGKDRIDEIGFASSSFDIEKLIASNPSCGTFIIDEACFYDERLIFVLN
KISLNENILFILPTLLYNFRKESFNDTAKLLVEYSDKIYKLGAYCGHIDC
MEESFFSYRYYFYNNKEIPAPYFDPLLIVGGDEEIESAIYPNYATRCSMH
HYLVGKEYFFSFLKPFALLYSQGDKKFLENEIVALSTDVENSNFVNSLDS
ERAYEFRDEILRNILELPFLAERALITLFSEYSILSKDNFKDLVFKFSLN
KDYINKIFFSKEGKEIF
>BAPKO_2074 thyX, Thymidylate synthase (EC 2.1.1.148)
MNKEYKILDNGFIKLIDFMGNDKRIVEAARISYRGDSVKRKDEELIDYLI
RNGHTSPLEQVVFTFHVKAPIFIARQWMRHRTARINEVSGCYSLAREEFY
VPLEEDLKYQISSNSQPKREFDSLEKKLSDKIKYHQKHSYKLYQDMVNSN
IPKELSRIVLPLSLYTEWYWQIDLNNLFHFIKLRLALDNPKEIKENSPKE
MREYAKALISIIKEIVPISFNSFENHFLRGKRFSREEIIAIVNALDLNKL
SMDAEKLDLLKDKLGID
>BAPKO_0846 tmk, thymidylate kinase
MIKILKNFYCIEGIDGSGKTSIINKLKTICKNESRYYFTKEPSSGIIGEM
IKEQLMNFKNPLKESIFAYLYAADRHDHLYKKGGILEILNTKSTKIITDR
YLFSSIAYQGKLGYELNKNFPLPEKVFFIKIDPKIAYERIQKNRTQSDLF
ELEKYKTFEQITLKYLKTFKKIEKTINVIYIDNSIKDNLDKNAEKIFNLI
KF
>BAPKO_0014 udk, uridine kinase
MAKIIGISGGSGSGKTTVVSKISEFIPEFVLISQDNYYKSVGDYEYEFSK
VNFDHPDAFDNNLFYEHLKNLKKNSPIDMPLYDFINHKRQLKTVLVVPTP
VIIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLRRDISKRGRTLES
VIDQYLNTTRWGYYRFIEPTKEYADLIIPEGGHNDKALYVLSTFLKSLSK
EGGLDFI


# Borrelia burgdorferi ZS7, ZS7

>BbuZS7_0747 putative adenylyl cyclase CyaB
MFEIESKAFIPTKELKRIIKLANKKFKFIKEEIKTDIYYSNQKKIIRIRK
LNTLEKIVTFKKKILDNNNTVEINKEIEFKIDSINNFLTLIKELKFKKLY
KKIKKSLIYQTNNLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIDNI
INQFGLKENIETRPYSELLSLANQSKK
>BbuZS7_0244 deoxyguanosine/deoxyadenosine kinase
MVIVIEGLIGVGKTTLGNILSKELEVPFYSELNNDFTLAVLDKFYKDKSR
WAFPVQINFLNERFKLIKGVFRTKGGILDRSIYGDCVFASLLNCDGHISD
EEYKIYIDLLDNMLEHSQRPSLLVYLDCSIDEVERRIKNRNRSFEMNIPR
DYLEGLNRKYLKWYDEYNLSSKIKFSYDNINIFSEEDRNKVISLIRDKLV
L
>BbuZS7_0413 DNA/RNA non-specific endonuclease
MKKRSKFFLYCYILCLTGFLFFSLNPKALKQIKHKIYDYLEIIENKYTDI
TKSIPIKEAQLIPKGYLTTQIISKKHYTLGYAESARQSEWTAYPLKREMV
ELALTLLKSKKIKRSTKFFEDTNIKGAFPKLEDYFKSGYDRGHIVSSADM
SFSENAMKDTYFLSNMSPQKSEFNSGIWLKLEKLVREWAISKGYIYIISA
GILTENKGFIGKNKILIPKNFYKIVLAINNNNYYDIISFIIPNEKAKDLD
LENYVVSVDLIEKKTKIDFFEKLDSKIKKNIKKIKNTHSWKFK
>BbuZS7_0252 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family protein
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLK
AKALFEILNNNQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNE
KNQLILDLMKNEKNRKAYFICNISYISKNGQILNFEGIIKGKIALSLNDK
KNYGFGYDSIFLTKNNKKLSDLTLEEKNKISHRGIAFLKFKKFLLKSLFN
S
>BbuZS7_0821 thymidine kinase
MGFCLDFANKEDTKLNNIVSVSHFDFRVKINLILVVGPMGSGKTEYAAKI
YKDSLVVRKKSFKVLGNIIKGNRSRVNVFFIRNFLDKRRFQDYPENVIPY
RGGGKDKIDEIGYASNSFDIENLIASNPSCGTFIIDEACFYDERLIFVLN
KISSNENILFILPTLLYNFRKESFNDTAKLLVEYSDKIYKLGAYCGHIDC
MEESFFSYRYYFYNNKEIPAPYFDPLLIVGGDEEIESAIYPNYSTRCSMH
HYLIGKEYFFSFLKPFALLYSQGDKKFLENEIVALSTDVENSNFVNSLDS
EKAREFRAEILRNILELPFLAERALITLFSEYSILSKDNFKDLVFKFSLN
KDYINKIFFSKEGKEFF
>BbuZS7_0554 phosphoribosyl pyrophosphate synthetase
MNLLKKKSIGIIACPGGRVFASKIIEELDRIFINIENEIIESICQDSKAL
KEEIFKIEKVLSPFLEGLSLSTLKSKEPLEIPVKFVKFANGEFKTEILKT
IRNKDIFIVQDVANAYEVEINSSEKIIMTVNDHIMNLMTTIDACMQAKAN
SVSVIIPSYPYSRQDKKHSRECLTASLIGRFLEELGIRHILTLDIHSKAI
ENVFRKVYFENLNVSYEIFNSLKDLIDIRDSNLVIVSPDTGAVSRNKFFA
SSLKSPLALLYKERDYSRVSNDVADSNISVTKLLGDVEGKNVFMSDDMLA
TGGTLIKAMKLLKSMGAKKIICGISLPFFNGDAIKYFDKAYEEGFFYKII
GTNAVWHNDELINKPWYHEANVAPLFAEAIFAIYNKVGLQKILDRKDDIQ
KLITKG
>BbuZS7_0849 cytidylate kinase
MKIALSGKSGCGNTTVSGMIAKHYGLEFINYTFHDIAREHNIPFSEFYEK
EIIGRNDYYWDKYLDNRLSVLSRKNNTVLASRLAIWISKSADLKIYLYAK
MEVRAERIMTREGGMYSDVLSSTFIRDENDKKRYLAIYNIDIDDYFSETD
LVIDVTNINPNEVFELIRDEIDKRNLKKIS
>BbuZS7_0475 nucleoside diphosphate kinase (NDK)
MSMLLQKTLCIVKPDGVRRGLIGDVVSRFERVGLKMVAAKMLIVDESLAK
KHYLYDDIVFRHSEAVWNSLIKFISNSPVFTFVVEGVESIEVVRKLCGAT
EPKLAIPGTIRGDFSYHSFKYSNEKGFSIYNVIHASANEADAMREIPIWF
KDNEILNYKRDDECEHYYC
>BbuZS7_0381 protein kinase C1 inhibitor
MYDCIFCKIINKELPSYKVYEDDLVLAFLDINPLTVGHTLVIPKEHSESL
LNMDDKFNERVLKVCKKISNALKRINSSIYGGINIYSALGAGAGQEVFHT
HFHVIPRFKNDGFGFKRGNKLNLEVEKFKELSMQISMNI
>BbuZS7_0419 adenylate kinase (ATP-AMP transphosphorylase)
MGLVFLGPPGSGKGTISKIISNEFKYQHISTGDLFRENILNSTALGQEIK
KIVERGELVPDLITIKIVEDKIKAIKKNKDFILDGFPRNICQAEALDKFL
PNVKIINFLIDEELVIKRLSGRRICKSCNNIFNIYTLTTKKNGICDVCGG
DLYQREDDKEECLKTRLKEYKLQTKPLIEFYSKCSRLNNVDASVKIDEIK
KKIIKIMLKKN
>BbuZS7_0433 nucleoside 2-deoxyribosyltransferase superfamily protein
MKIYLASPFFKEEEIKLRDEVLKFLEEFNLEVFSPEHHAVKKMGLLEKVD
YKFVNRDIREKIREIDLKELVSSDIVLALVNYVDSGTAYERGFAFAKKIP
SIDFFKDKQDSDFYNLMYSDCAAAFSNYKDLREGILTFKELWIKFKGDNE
NFRTFFDYLKAKLGNKLKKIFTTLPVNEKCGC
>BbuZS7_0377 putative nucleosidase, Pfs protein
MILIISAMQEESEEINKILDNKEEIVLNNYLENKKIYKGKILGKDVISLT
TGIGKVNAATWSSQIISKYKITHIINSGSSGGIKENSNLKILDIIVSSET
AYYDFDLTKFGHKIGQVPNLPQKFKADEELLKKVANIVDNKLLNIDIHIG
LILTGDQFVDNEKNLETIKKNFKDALAVDMEGAAIAQVAHIFKIPFIIIR
SISDLPNNKDNHIDFNKFLKTSSINSSKMTKELIRLI
>BbuZS7_0583 uridylate kinase
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGRV
AREYQDAYKKINPDFKVHELDEIGIISTRLNAEFLSKVMNPFCKDKIVTN
PLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDIINITNVNQVYD
KDPKKFKNATAFKKLNWKQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLT
LYIVNGNNIKNLEKVFNKNNDFFGTIIVK
>BbuZS7_K13 adeC, adenine deaminase
MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFID
AHIHIESSFLIPSNFAHLVVAHGTVATISDPHEIANVNGIDGINFMINNS
KKTEFKFFFGAPSCVPALSQEFETSGYVLNDKDIDELMKLDDIYYLAEVM
DFKGVINKDIEIINKINSALKRNKVVDGHAPGLSPNLTLKYASSGISTDH
ECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECSKKYCDSLMFC
FDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLL
RIGDPADFIITKDIKTFKINKTYINGKLVFNDGISLIPLINEIPINNFNC
SKKSISDFKFSTKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAED
ILKIAIINRYKDNSKISIGFIKNFGIRNGAIGSTVAHDSHNIILVGSNDE
YLCKAANTIIQNKGGLCALNNEKTIIMELPISGLMSTLSAERVASQYIKL
NDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDVDSFCFVDY
>BbuZS7_0806 apt, adenine phosphoribosyltransferase
MKNKTEYYDQFISKIPNFPKKGVLFYDITSVLLKPEVYSSLINEVYSFYN
FKKIDCIAVVESRGYLIGAPLSLKMQLPLVLIRKEGKLPREVFSEEYELE
YGFGRIEVHKDDVRMYSNILLIDDILATGGTLKSSAILLERAGGKVKDIF
CFIELCAINGRQSLESYEVNSLVRYN
>BbuZS7_0128 cmk, cytidylate kinase
MIIAIDGPSASGKSSIARELGVRLNYKFISSGHLYRIITLIAQRSLMNSC
DFISEDSLLNLILENDISFNNSTFLLNGENVENQILNDKIDFQVSFYSSY
VGIRNIVNKKLREVVKFSDDNYIIEGRDITTVVFPESEFKIYLDASVKVR
ALRRYKQRNGNETLEELERTLKRRDDVDKKKQYGKLKLSKGVFYLDTSYK
GLDDVCNIIIEKFNLKKVRER
>BbuZS7_B17 guaA, GMP synthase
MNTQAILVLDFGSQYSQLIARRIREIGVYTKVIPYYTPLKEIKNMNISGI
ILGGSPASVYSKEAPTLDMEIFNLKIPVLGICYGMQIIVKLFGGLVSKDS
KQEYGSSEIFLRDEKSLLFSELPNKFKIIMSHGDSIEKIPDNFKQLAFTK
NCIASISNETQKIYGLQFHPEVTHSEFGDQILKNFVFKICQAQINWSLEG
NLETIVKKIKLKVGSKKVILGLSGGTDSLVCALLIKKAINENLICVFVNT
GLLRKNEDKKILELKHQYDLNIKFIDASIKFLNRLKNISDPEEKRKIIGK
EFVDVFEKITLEDQNIEYLAQGTIYSDVIESKSKDSSSSKIKSHHNVGGL
PDKMSLKLLEPLNEFFKDEIIQIGINLGIKKESLYRHPFPGPGLAIRIIG
EVTQEKINILQEADNILTEELFINDLYYQIRQAFVVLLPVKSVGVMGDQR
TYEYTAVIRCVNTQDFMTAEWTELPYSFLKKVSSRIINEVRGINRVCYDI
SSKPPSTIEWE
>BbuZS7_B16 guaB, inosine-5'-monophosphate dehydrogenase
MPNKITKEALTFDDVSLIPRKSSVLPSEVSLKTQLTKNISLNIPFLSSAM
DTVTESQMAIAIAKEGGIGIIHKNMSIEAQRKEIEKVKTYKFQKTINTNG
DTNEQKPEIFTAKQHLEKSDAYKNAEHKEDFPNACKDLNNKLRVGAAVSI
DIDTIERVEELVKAHVDILVIDSAHGHSTRIIELVKKIKTKYPNLDLIAG
NIVTKEAALDLISVGADCLKVGIGPGSICTTRIVAGVGVPQITAICDVYE
ACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKESPSEEII
YNGKKFKSYVGMGSISAMKRGSKSRYFQLENNEPKKLVPEGIEGMVPYSG
KLKDILTQLKGGLMSGMGYLGAATIFDLKINSKFVKISHSSLKESHPHDV
FNIT
>BbuZS7_0601 mtnN, MTA/SAH nucleosidase
MNNCLIKFFIFLLVFSNSYVAFSKNVNVLIVTAMDSEFDQINKLMSNKEE
IVLKEYGLNKKILKGKLSNRNVMVIICGVGKVNAGVWTSYVLSKYNISHV
INSGVAGGVVSAKYKDIKVGDVVVSSEVAYHDVDLTKFGYKVGQLTGGLP
QKFNANKSLIKNAIEAIKSKVGGFNAYSGLIVSGDQFIDSTYINKIIGNF
KDVIAVEMEGAAIGHVSHMFNIPFIVIRSISDIVNKEGNEVEYSKFSKIA
AFNSAKVVQEILRKL
>BbuZS7_I07 mtnN, MTA/SAH nucleosidase
MKIKNIANILIFFLSIVLNSWGNESKINTPNENSQSNILIISATKAEIEE
INKIIQNKKYISIEEHRRKKKIAIGKLMDHNIITIATGVGKINTALWTSY
IISKYKISHIINAGVASGIYSDKNKFIKIGDVVISTETTSYDFDLHRFGY
EIGHVPEHPKKFKANTALIRKTSKIKINNITSYMGLIITGDQFIDHQTFQ
EIPEEFENAIAIDMESAAMAQVAYGFKIPFIIIRGISDIVNNENNYDDYK
KFLKKASSSSAKIVENLIKLM
>BbuZS7_0588 pyrG, CTP synthase
MKKNLKILVITGGVISGIGKGVTSASIARLFRYDFRVTPIKCDGYLNTDP
GTINPVEHGEVFVLDDGGEVDMDFGHYERFLNLNAKSSWNITMGKIYKKI
LENERKGKYLGRTVQLIPHVTDEIKSTIFQIASSENSDMLIIEIGGTVGD
MENILFIETVRQIRQEIGSGNISFIHLTYVPSPAGINEQKSKPTQQSVKT
LNKAGIFPDLIIARSSQVLTDQIRKKVAMFCNVESTSIIDNVDVSTIYEI
PISFYKQGVHEILSSKLNIKVDPKIEELSKLVGVIKSNFFVPKKIINIAI
CGKYAELDDSYASIRESLVHVAAHLDLLIKSTLIDSNDLNESCLKEFDGI
IVPGGFGGKGYEGKIMAIKYARENNIPFLGICLGLQLAVIEFARNVCGIL
DADTEENLARDKPLKSPVIHLLPEQKGIKDKGATMRLGGYPVILKKNTIA
FKLYGQDRIIERFRHRYEVNNDYIDLFAKNGLIVSGFSSDFKMAKLIEIP
ENKFFVACQFHPELITRIENPAKLFLGLIKACI
>BbuZS7_A66 thyX, thymidylate synthase, flavin-dependent
MNKEYKILDNGFLKLIDFMGDDRRIVKAARISYREESVKRKDAELIDYLI
RNGHTSPLEQVVFTFHVKAPIFVARQWMRHRTARINEVSGCYSLAREEFY
VPLEEDLRCQTSSNSSEKEFKSLEKLSDKIKHHQKHSYELYQDMINANIP
KELSRIVLPLSLYTEWYWQIDLNNLFHFIKLRLALDSPKEIKENSPKEMR
EYAKALISIVREIVPIAFNSFENHFLRGKRFSHEEIIAIINALDLNKLSM
DAEKLNLLKDKLGID
>BbuZS7_0823 tmk, thymidylate kinase
MIKILKNFYCIEGIDGSGKTSITNKLKALCNDESRYYFTKEPSSGIIGEM
IRKQLMNFENPLEESTFAYLYAADRHDHLYKKGGILEILNTKSRKIITDR
YLFSSIAYQGKLGYELNKNFPLPEKVFFIETDPNIAYERIQKNRTQSDLF
ELEKYKTFEQIALKYLKIFKKLEKKINVIYINNSIKDNLDKNAKKIFNLI
KF
>BbuZS7_0015 udk, uridine kinase
MAKIIGISGGSGSGKTTVVSKISEFIPEFVLISQDNYYKSVGDYEHEFSK
VNFDHPDAFDNNLFYEHLKNLKKNSPIDMPLYDFINHKRQLKTVLVVPTP
VVIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLRRDISKRGRTVES
VIDQYLNTTRWGYYRFIEPTKEYADLIIPEGGHNDKALYVLSTFLKSLSK
EGLDFT


# Borrelia burgdorferi, B31

>BB_B17 IMP dehydrogenase (guaB)
MPNKITKEALTFDDVSLIPRKSSVLPSEVSLKTQLTKNISLNIPFLSSAM
DTVTESQMAIAIAKEGGIGIIHKNMSIEAQRKEIEKVKTYKFQKTINTNG
DTNEQKPEIFTAKQHLEKSDAYKNAEHKEDFPNACKDLNNKLRVGAAVSI
DIDTIERVEELVKAHVDILVIDSAHGHSTRIIELIKKIKTKYPNLDLIAG
NIVTKEAALDLISVGADCLKVGIGPGSICTTRIVAGVGVPQITAICDVYE
ACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKESPSEEII
YNGKKFKSYVGMGSISAMKRGSKSRYFQLENNEPKKLVPEGIEGMVPYSG
KLKDILTQLKGGLMSGMGYLGAATISDLKINSKFVKISHSSLKESHPHDV
FSIT
>BB_0379 protein kinase C1 inhibitor (pkcI)
MLFFYNRIFLMYDCIFCKIINKELPSYKVYEDDLVLAFLDINPLTVGHTL
VIPKEHSESLLNMDDKFNERVLKVCKKISNALKRINSSIYGGINIYSALG
AGAGQEVFHTHFHVIPRFKNDGFGFKRGNKLNLEVEKFKELSMQISMNI
>BB_E07 predicted coding region BBE07
MGLIVSGDQFIDLKYMNKIIKNFKDVIVIEMEGVVIGHVAHTFNVYFIVI
GPYGYFK
>BB_0239 deoxyguanosine/deoxyadenosine kinase(I) subunit 2 (dck)
MEVDLVIVIEGLIGVGKTTLGNILSKELEVPFYSELNNDFTLAVLDKFYK
DKSRWAFPVQINFLNERFKLIKGVFRTKGGILDRSIYGDCVFASLLNCDG
HISDEEYKIYIDLLDNMLEHSQRPSLLVYLDCSIDEVERRIKNRNRSFEM
NIPRDYLEGLNRKYLKWYDEYNLSSKIKFSYDNINIFSEEDRNKVISLIR
DKLVL
>BB_0547 conserved hypothetical protein
MGRNPLIIGVTGRIASGKDTVSKIISNKYGFYEINADKLGHSVLHEKKEE
IVKIFGQKILNTKNEIDKLLLRNLVFNDNKELKKLESVSHPVILSKIKKI
LIQNQSTKIIINAALLFKMNLEKLCDYIIVLKAKNSIIKNRLSYSIPNID
SNMINKILKIQKDIFFEKNIINLKIINIINNKNYAYLEKEIEKKMQGIIN
YERFE
>BB_0571 uridylate kinase (smbA)
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGRV
AREYQDAYKKINPDFKVHELDEIGIISTRLNAEFLSKVMNPFCKDKIVTN
PLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDIINITNVNQVYD
KDPKKFKNATAFKKLNWKQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLT
LYIVNGNNIENLEKVFNKNNDFFGTIIVK
>BB_0375 pfs protein (pfs-1)
MILIISAMQEESEEINKILDNKEEIVLNDYLENKKIYKGKILGKDVISLT
TGIGKVNAATWSSQIISKYKITHIINSGSSGGIKENSNLKILDIIVSSET
AYYDFDLTKFGHKIGQVPNLPQKFKADEELLKKVANIVDNKLLNIDIHIG
LILTGDQFVDNEKNLETIKKNFKDALAVDMEGAAIAQVAHIFKIPFIIIR
SISDLPNNKDNHIDFNKFLKTSSINSSKMTKELIRLI
>BB_0575 CTP synthase (pyrG)
MKKNLKILVITGGVISGIGKGVTSASIARLFRYDFRVTPIKCDGYLNTDP
GTINPVEHGEVFVLDDGGEVDMDFGHYERFLNLNAKSSWNITMGKIYKKI
LENERKGKYLGRTVQLIPHVTDEIKSTIFQIASSENSDMLIIEIGGTVGD
MENILFIETVRQIRQEIGSGNISFIHLTYVPSPAGINEQKSKPTQQSVKT
LNKAGIFPDLIIARSSQVLTDQIRKKVAMFCNVESTSIIDNVDVSTIYEI
PISFYKQGVHEILSSKLNIKVDPKIEELSKLVGVIKSNFFVPKKIINIAI
CGKYAELDDSYASIRESLVHVAAHLDLLIKSTLIDSNDLNESCLKEFDGI
IVPGGFGGKGYEGKIMAIKYARENNIPFLGICLGLQLAVIEFARNVCGIL
DADTEENLARDKPLKSPVIHLLPEQKGIKDKGATMRLGGYPVILKKNTIA
FKLYGQDRIIERFRHRYEVNNDYIDLFAKNGLIVSGFSSDFKMAKLIEIP
ENKFFVACQFHPELITRIENPAKLFLGLIKACI
>BB_0015 uridine kinase (udk)
MMAKIIGISGGSGSGKTTVVSKISEFIPEFVLISQDNYYKSVGDYEHEFS
KVNFDHPDAFDNNLFYEHLKNLKKNSPIDMPLYDFINHKRQLKTVLVVPT
PVVIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLRRDISKRGRTVE
SVIDQYLNTTRWGYYRFIEPTKEYADLIIPEGGHNDKALYVLSTFLKSLS
KEGLDFT
>BB_0723 conserved hypothetical protein
MFEIESKAFIPTKELKRIIKLANKKFKFIKEEIKTDIYYSNQKKIIRIRK
LNTLEKIVTFKKKILDNNNTVEINKEIEFKIDSINNFLTLIKELKFKKLY
KKIKKSLIYQTNNLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIDNI
INQFGLKENIETRPYSELLSLANQSKK
>BB_0618 cytidine deaminase (cdd)
MEKLKQEDIDKAFYMAEKARNNSYSPYSKFKVGACIKTKTNDFFIGTNVE
NASFGATCCAERSAILNMIAKIGVQEIDFLLLNTSPECIPCAICLQVMAE
FFNQDTKIIITESKSFSENKTPIKIYTLKDLLKSPFDKKELRRVTYSELE
KKLI
>BB_0417 adenylate kinase (adk)
MGLVFLGPPGSGKGTISKIISNEFKYQHISTGDLFRENILNSTALGQEIK
KIVERGELVPDLITIKIVEDKIKAIKKNKDFILDGFPRNICQAEALDKFL
PNVKIINFLIDEELVIKRLSGRRICKSCNNIFNIYTLTTKKNGICDVCGG
DLYQREDDKEECLKTRLKEYKLQTKPLIEFYSKCSRLNNVDASVKIDEIK
KKIIKIMLKKN
>BB_0544 phosphoribosyl pyrophosphate synthetase (prs)
MNLLKKKSIGIIACPGGRVFASKIIEELDRIFINIENEIIESICQDSKAL
KEEIFKIEKVLSPFLEGLSLSTLKSKEPLEIPVKFVKFANGEFKTEILKT
IRNKDIFIVQDVANAYEVEINSSEKIIMTVNDHIMNLMTTIDACMQAKAN
SVSVIIPSYPYSRQDKKHSRECLTASLIGRFLEELGIRHILTLDIHSKAI
ENVFRKVYFENLNVSYEIFNSLKDLIDIRDSNLVIVSPDTGAVSRNKFFA
SSLKSPLALLYKERDYSRVSNDVADSNISVTKLLGDVEGKNVFMSDDMLA
TGGTLIKAMKLLKSMGAKKIICGISLPFFNGDAIKYFDKAYEEGFFYKII
GTNAVCHNDELINKPWYHEANVAPLFAEAIFAIYNKVGLQKILDRKDDIQ
KLITKG
>BB_H33 predicted coding region BBH33
MNLFKIEANYIDILNKEIYLASITIANGHIVSMTKINAILDEYILPGFID
AHIHIERSFFIPSNFTHLVVQHSTVATISDPHEIVNVFFRI
>BB_0247 conserved hypothetical protein
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLK
AKALFEILNNNQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNE
KNQLILDLMKNEKNRKAYFICNISYISKNGQILNFEGIIKGKIALSLNDK
KNYGFGYDSIFLTKNNKKLSDLTLEEKNKISHRGIAFLKFKKFLLKSLFN
S
>BB_0777 adenine phosphoribosyltransferase (apt)
MKNKTEYYDQFISKIPNFPKKGVLFYDITSVLLKPEVYSSLINEVYSFYN
FKKIDCIAVVESRGYLIGAPLSLKMQLPLVLIRKEGKLPREVFSEEYELE
YGFGRIEVHKDDVRTYSNILLIDDILATGGTLKSSAILLERAGGKVKDIF
CFIELCAINGRQSLESYEVNSLVRYN
>BB_0128 cytidylate kinase (cmk-1)
MIIAIDGPSASGKSSIARELGVRLNYKFISSGHLYRIITLIAQRSLMNSC
DFISEDSLLNLILENDISFNNFAFLLNGENVENQILNDKIDFQVSFYSSY
VGIRNIVNKKLREVVKFSDDNYIIEGRDITTVVFPESEFKIYLDASVKVR
ALRRYKQRNGNETLEELERTLKRRDDVDKKKQYGKLKLSKGVFYLDTSYK
GLDDVCNIIIEKFNLKKVRER
>BB_0791 thymidine kinase (tdk)
MGFCLDFANKEDTKLNNIVSVSHFDFRVKINLILVVGPMGSGKTEYAAKI
YKDSLVVRKKSFKVLGNIIKGNRSRVNVFFIRNFLDKRRFQDYPENVIPY
RGGGKDKIDEIGYASNSFDIENLIASNPSCGTFIIDEACFYDERLIFVLN
KISSNENILFILPTLLYNFRKESFNDTAKLLVEYSDKIYKLGAYCGHIDC
MEESFFSYRYYFYNNKEIPAPYFDPLLIVGGDEEIESAIYPNYSTRCSMH
HYLIGKEYFFSFLKPFALLYSQGDKKFLENEIVALSTDVENSNFVNSLDS
EKAREFRAEILRNILELPFLAERALITLFSEYSILSKDNFKDLVFKFSLN
KDYINKIFFSKEGKEFF
>BB_0588 pfs protein (pfs-2)
MNNCLIKFFIFLLVFSNSYVAFSKNVNVLIVTAMDSEFDQINKLMSNKEE
IVLKEYGLNKKILKGKLSNRNVMVIICGVGKVNAGVWTSYILSKYNISHV
INSGVAGGVVSAKYKDIKVGDVVVSSEVAYHDVDLTKFGYKVGQLTGGLP
QKFNANKNLIKNAIEAIKSKVGGSNAYSGLIVSGDQFIDPTYINKIIGNF
KDVIAVEMEGAAIGHVSHMFNIPFIVIRSISDIVNKEGNEVEYSKFSKIA
AFNSAKVVQEILRKL
>BB_A76 thymidylate synthase-complementing protein (thy1)
MNKEYKILDNGFLKLIDFMGDDRRIVKAARISYREESVKRKDAELIDYLI
RNGHTSPLEQVVFTFHVKAPIFVARQWMRHRTARINEVSGCYSLAREEFY
VPLEEDLKCQTSSNSSEKEFKSLEKLSDKIKHHQKHSYELYQDMINANIP
KELSRIVLPLSLYTEWYWQIDLNNLFHFIKLRLALDSPKEIKENSPKEMR
EYAKALISIVREIVPIAFNSFENHFLRGKRFSHEEIIAIINALDLNKLSM
DAEKLNLLKDKLGID
>BB_K17 adenine deaminase (adeC)
MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFID
AHIHIESSFLVPSNFAHLVVAHGTVATISDPHEIANVNGIDGINFMINNS
KKTEFKFFFGAPSCVPALSQEFETSGYVLNDKDIDELMKLDDIYYLAEVM
DFKGVINKDIEIINKINSALKRNKVVDGHAPGLSPNLTLKYASSGISTDH
ECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECSKKYCDSLMFC
FDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLL
RIGDPADFIITKDIKTFKINKTYINGKLVFNDGISLIPLINEIPINNFNC
SKKSISDFKFSTKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAED
ILKIAIINRYKDNSKISIGFIKNFGIRNGAIGSTVAHDSHNIILVGSNDE
YLCKAANTIIQNKGGLCALNNEKTIIMELPISGLMSTLSAERVASQYIKL
NDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDVDSFCFVDY
>BB_0819 cytidylate kinase (cmk-2)
MKIALSGKSGCGNTTVSGMIAKHYGLEFINYTFHDIAREHNIPFSEFYEK
EIIGRNDYYWDKYLDNRLSVLSRKNNTVLASRLAIWISKSADLKIYLYAK
MEVRAERIMTREGGMYSDVLSSTFIRDENDKKRYLAIYNIDIDDYFSETD
LVIDVTNINPNEVFELIRDEIDKRNLKKNS
>BB_I06 pfs protein (pfs)
MKIKNIANILIFFLSIVLNSWGNESKINTPNENSQSNILIISATKAEIEE
INKIIQNKKYISIEEHRRKKKIAIGKLMDHNIITIATGVGKINTALWTSY
IISKYKISHIINAGVASGIYSDKNKFIKIGDVVISTETTSYDFDLHRFGY
EIGHVPEHPKKFKANTALIRKTSKIKINNITSYMGLIITGDQFIDHQTFQ
EIPEEFENAIAIDMESAAMAQVAYGFKIPFIIIRGISDIVNNENNYDDYK
KFLKKASSSSAKIVENLIKLM
>BB_0463 nucleoside-diphosphate kinase (ndk)
MSMLLQKTLCIVKPDGVRRGLIGDVVSRFERVGLKMVAAKMLIVDESLAK
KHYLYDDIVFRHSEAVWNSLIKFISNSPVFTFVVEGVESIEVVRKLCGAT
EPKLAIPGTIRGDFSYHSFKYSNEKGFSIYNVIHASANEADAMREIPIWF
KDNEILNYKRDDECEHYYC
>BB_B18 GMP synthase (guaA)
MKYTLIKKVLIYLRTYIMNTQAILVLDFGSQYSQLIARRIREIGVYTKVI
PYYTPLKEIKNMNISGIILSGSPASVYSKEAPTLNMEIFNLKIPILGICY
GMQIIVKLFGGLVSKDSKQEYGSSEIFLRDEKSLLFSELPNKFQIIMSHG
DSIEKIPDNFKQLAFTKNCIASISNETQKIYGLQFHPEVTHSEFGDQIIK
NFVFKICQAQINWSLEGNLETIVKKIKLKVGSKKVILGLSGGTDSLVCAL
LIKKAINENLICVFVNTGLLRKNEDKKILELKHQYDLNIKYIDASTKFLN
RLKNISDPEEKRKIIGKEFVDVFEKITLEDQNIEYLAQGTIYSDVIESKS
KDSSSSKIKSHHNVGGLPDKMSLKLLEPLNEFFKDEIIQIGINLGIKKES
LYRHPFPGPGLAIRIIGEVTQEKINILQEADNILTEELFINDLYYQIRQA
FVVLLPVKSVGVMGDQRTYEYTAVIRCVNTQDFMTAEWTELPYSFLKKVS
SRIINEVRGINRVCYDISSKPPSTIEWE
>BB_0411 endonuclease precursor (nucA)
MVELALTLLKSKKIKRSTKFFEDTNIKGAFPKLEDYFKSGYDRGHIVSSA
DMSFSENAMKDTYFLSNMSPQKSEFNSGIWLKLEKLVREWAISKGYIYII
SAGILTENKGFIGKNKILIPKNFYKIVLAINNNNYYDIISFIIPNEKAKD
LDLENYVVSVDLIEKKTKIDFFEKLDSKIKKNIKKIKNTHSWKFK
>BB_0793 thymidylate kinase (tmk)
MEKIIKTKIKNGKINNINVLLLKNNKFIHSIDNYYYIIIIDNLIIDTKRK
EEKIFVIKILKNFYCIEGIDGSGKTSITNKLKALCNDESRYYFTKEPSSG
IIGEMIRKQLMNFENPLEESTFAYLYAADRHDHLYKKGGILEILNTKSRK
IITDRYLFSSIAYQGKLGYELNKNFPLPEKVFFIETDPNIAYERIQKNRT
QSDLFELEKYKTFEQIALKYLKIFKKLEKKINVIYINNSIKDNLDKNAKK
IFNLIKF


# Borrelia duttonii Ly, Ly

>BDU_248 rdgB/HAM1 protein
MKTLFFATSNINKINEVKQILDIPKIKIEIPQNFDIKETGKTFKENSLLK
AKALFKILNNKQPVFSEDSGLCIEALNMEPGIYSKRYDQYKLGKKLDNNE
KNHLIIDLMREKNNRTAYFICVISYIDVDGTINNFEGMLKGTIALNIDYY
QKNGFGYDPIFLTTNNKRLSELNLEEKNKISHRGIAFDKFKKFLMQFLD
>BDU_726 adenylyl cyclase, CyaB-type, putative
MFEVELKAFIPKNRVKKIVKLANQKFQFIKEEIKNDIYYFNSKKIIRIRE
SNISKKIITFKIKSLEKDIEINKEIEFKVDKIENFISFIKELDFKILYKK
IKKSLIYKKDNLNIEVNEIQNLGFFLEIEKIIDNKNELNLAKQEIYKTIQ
DFKLQNNIEKKSYFELLSNQLKK
>BDU_831 cytidylate kinase
MRIAISSKSGCGNTTVSSMLAKYYGLKLINYTFHDIAREKNIPFDTFYEK
EIMGRNDYYWDEYLDNKLLKLSKEDNTILASRLAIWLSKDADLKIYLYAK
IEIRAERIINREGGMYSDILVSTFNRDFNDSKRYLSVYNINIDNYLDVAD
FIVDTTDQSANRVFELIKNEIEKRNLYVK
>BDU_1143 Inosine-5'-monophosphate dehydrogenase
MMDKIVKEALTFDDVSLIPRKSSILPSDVNLKTRLTRNIYLNIPFLSSAM
DTVTESRMAIAVAKEGGIGVIHKNITIEKQRKEVEIVKSYHRNGIIRNLI
TINEDTSIKEARRLIVKHNISALPVTDHAGKILGLVTSRDIKYIADDNTP
VINAMTKKLITAKEDITLSEAKEILFKHRIEKLLIVDESNSLRGLITCKD
IDHVEHQEYFPNACKDMNDRLRVGAAVSTDVDTLERVEELVKADVDVIVV
DSAHGHSTKVIEIVRKIKSKYPNLDVIAGNIVTKEAAFDLIDAGADCLKV
GIGPGSICTTRIVAGVGVPQLTAINDVFEACKDTNICIIADGGIRFSGDI
VKAIAAGADSVMIGNLFAGAHESPSEEVMYNGKKFKIYVGMGSLAAMARG
SKSRYFQFESKDSPGKLVPEGIEGMVPYVGKVKDIIFQLKGGLMSGMGYL
GVETILELKRDSKFVKISSASLRESHTHDVLEN
>BDU_2010 uncharacterized conserved protein
MLMVDLPMHKFSFSGSEKSFLPGFEHKSGIHETESAIVDADSEAILPGDL
VIASKSSNMGDILVKKATSSTTNTDVVRGFAMRKTYIPSYETEKYLPGEV
VPIRRRGEVVVTLDTSYTTPKIGHYVFFKEGKLVQDKNGKGGVQVGRIKD
ISISTSSKVVLLDAQIGHEYDTSGNRKFSS
>BDU_310 uncharacterized conserved protein
MIIIFLFLFSISNLYSFLEFGKDEKFDLIDDFGEIKNDTLNIGIKLRALD
THFSIFSNNYKVLYSKNKINEYDKSVLIIFDKDLNFNLEFFGDFVYKDDK
VFLMDNKNFDIVVVDHYNRQIINPLFVIKNRNNLNIISSFFVSELFLKSK
DDIVFSLKENVDLDLELGNYTLVLNFLKRDVAKESKILSGIYYFEVLLNN
NSVFRIDFQSMYLNGNSYVVSGNKNYNLNVFDLKKNNGSIKIDNLEFTNG
SNEIKIKYGDVYNVENSLTYRFTLNG
>BDU_1078 thymidylate synthase protein
MHDHVDAAEEILDREYKVLDKGFLRLIDYMGSDERIVNSARVSYRDSKAK
RDSAALIDYLIRNEHTSPFEQVVFTFHVKAPIFVARQWMRHRTSRINEVS
GRYSLMREEFYVPLREDIKTQSLINKQGRSDEEIDIDVAISFLDGLDESY
KNAYKIYDDMIKKDVSRELARITLPLSLYTEWYWQIDLNNLFRFIKLRSS
GHAQKEIREYSNVLLDIVNLVVPLATSSFKKHILEGVMLSSEEVCEIRKA
LDLTKLNLSQKSLDRLKEKLNL
>BDU_411 adk, adenylate kinase
MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRTNIENDTPLGKEIK
QIVENGQLVPDSITIKVVEDKINTIDNRDNFILDGFPRNINQAIELDRLL
ENIKIINFLIDEKLLVKRLSGRRICQSCCKIFNIYTLPTKEKEICDFCQG
ILYQRKDDTKESLKIRLQEYNLQTKPLINFYSNSNRLNNIDASKNINEVQ
KNLMEIISKIEKN
>BDU_782 apt, adenine phosphoribosyltransferase
MIFLILMENLMIDKMGYYDRFIMKVPNFPKEGILFYDISNVLLQAEAYKS
LLEDAHALYSSKEIDCIAAIESRGYLIGAPLALKMNLPLLLIRKGGKLPR
QVLREEYELEYGLGSIEIHKDDIKQHTKILLVDDILATGGTIRAAVRLLE
RAGGVISDIFCFIELVSIRGRDILGEYNVNSLVRYP
>BDU_621 cdd, cytidine deaminase
MNDNGQDAIIKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNIE
NASFGATRCAEQAAIINMISSVGVQKIDFILVTTIPASVPCAICRQVMSE
FFEEDTKILITDPNQFNMNKKVFKIYTLNDLLKFPFNKEELSKIFKANKT
T
>BDU_132 cmk, cytidylate kinase
MIIAIDGPSASGKSSVSKALSMKLGFKFISSGYLYRIITLIAQRFTLNEY
DLLNESKLVDLISQNDIKYNDNSFLLNGVDVISHILTEKIDFQVSLYSSY
VNIRKIVNKKLREIVKIQDDDYIIEGRDITTVVFPEAKIKIYLDASVEVR
TLRRYNQRDDDMALIELEQALEKRDEIDQNKEYGKLKLGKGVFYIDTSYK
SLDDVCDIIIKTFNLKKK
>BDU_239 dck, deoxyguanosine/deoxyadenosine kinase(I) subunit 2
MEAGLVIVIEGLIGVGKTTLGHILSLDLEIPFYRELDNEFTLSMLNEFYK
DKFRWAFPMQISFLNERFKLIKSVFKSKGKGILDRSIYSDCVFASFLNDN
GYISDNEYKIYLDLLDNMLEHSKKPELMIYLDCSIAEAENRIKKRNRSCE
TDISKDYLEKLNKKYLTWYDSYNLSPKLMFNYDKINVFDDREKSNLITFI
KDKLVI
>BDU_1142 guaA, GMP synthase (glutamine-hydrolysing)(glutamine
MSNNALVILDFGSQYSQLIARKIREMGVYTIIVTYSLSAKEIKDMNPVGL
ILSGGPASVYLDEAPGVDIEIFDLGIPILGICYGMQLIIKVFGGVISKCD
KQEFGHTELFIDDNKADLFLELPSKFEVMMSHGDNIEKIPEGFKQIAYTK
VCVGAVFNLEKRIYGVQFHPEVSCCDIGNQIFMNFVFKICKAQTNWDLSN
SIEDLVKGIRHEVGDSKVILGLSGGIDSLVCALLINKAIKDNLICVFVDT
GFLRKNEANEILEFNKKYNLNIKHIDSSLLFLTNLRDVDDPEEKRKIIGK
TFVEIFEKVALEEDDIKYLAQGTIYSDVIESDVKNNVCSSKNIKSHHNVG
GLPDKINLNLLEPLRNLFKDEVIQLGVQLGLEEEVLYRHPFPGPGLAIRI
IGEITKDKIDILQGADHIFIEELLINNLYYKVRQAFVVLLPVRTVGVMGD
NRTYEYTAVIRCVNTLDFMTASWVELPYSFLRKVSSRIINEIRGINRVCY
DISSKPPATIEWE
>BDU_13003 guaB, inosine-5'-monophosphate dehydrogenase
MMDKIVKEALTFDDVSLVPRKSSILPSDVNLKTRLTRNIYLNIPFLSSAM
DTVTESRMAIAVAKEGGIGVIHKNITIEKQRKEVEIVKSYHRNGIIRNLI
TINEDTSIKEARRLIVKHNISALPVTDHAGKILGLVTSRDIKYIADDNIP
VINAMTKKLITAKEDITLSEAKEILFKHKIEKLLIVDESNSLRGLITCKD
IDHVEHQEYFPNACKDMNDRLRVGAAVSTDVDTLERVEELVKADVDVIVV
DSAHGHSTKVIEIVRKIKSKYPNLDVIAGNIVTKEAAFDLIDAGADCLKV
GIGPGSICTTRIVAGVGVPQLTAINDVFEACKDTNICIIADGGIRFSGDI
VKAIAAGADSVMIGNLFAGAHESPSEEVMYNGKKFKIYVGMGSLAAMARG
SKSRYFQFESKDSPGKLVPEGIEGMVPYVGKVKDIIFQLKGGLMSGMGYL
GVETILELKRDSKFVKISSASLRESHTHDVLEN
>BDU_418 hpt, hypoxanthine phosphoribosyltransferase
MSDKISTLFTEKKIKSKIKELAQKIRSYYKDKNNVVFISLLKGSFMFFAD
ITREIGLNVKIDFLQASSYGNKTLSSLNVLIKKDIEINIENCYVIIFDDI
VDTGLTYKKIIAHLQTKKPKEIKICTLFNKPSRRLTEIKIDYTGFEIQND
FIVGYGIDFNEKHRTLRSVAKINQ
>BDU_466 ndk, nucleoside-diphosphate kinase
MHIHELNKLCLIISLHCIKNIGRLFMSTLIQKTLCIVKPDGVRRGLIGNV
VSRFERVGLKIVAAKMVLVDRKMAEEHYLYDDIAARHGESVWKSLVNFLM
SSPVFAFVIEGVESVEVVRKFCGSTEPKMSVPGTIRGDFSYHSFNYANAK
NFAVYNVIHSSASLIDANREIPIWFTKDEIFTYKRDDEFEHYY
>BDU_1076 nrdE, ribonucleoside-diphosphate reductase, alpha subunit
MSYLEHHMMLRILWKGLVMRHLELNNEMMVLRDGFYRLEKDLEALSVFLE
EIKSKSLKFENPNERMHYLIDNNLYEDFYQKYSEDQILEIYKAVEGEEFK
FKSYMSASKFYKDYALKVKDTYFESYEDRIIAVSLFLADGCFDFALRLAL
DMIKQRYQPATPTFLNAGKYVRGELVSCFLLEVGDSLNSITFNISSAMQL
SKIGGGVALNLSNIRARGEEIRGICNVAKGVIPVMKLLEDGFNYADQMGQ
RKGAGAVYLNIFHYDIEDFLDTKKINADEKSRVQTLSLGVIIPDKFFELA
KQDKNYYALAPYSVYKETGLMMNDIDFDKDYDLLASNPRIIKKEISARDM
LVRIAKLQFESGYPYIMYQTSCNLNHPLKEVGRVKMSNLCTEIFQIQTPS
VIGNYGEGDVIGYDVSCILGSLNIVNVINSDFEFTVDLAMRALTSVVDKS
CINNAPSVRKANDDYRAVGLGVMNLHGFLIKNKIPYESDEALDFVRTFFM
LLNFYSLKSSMNIAKERNSVFKDFKQSEYYNGNYFNMYLNEDFSPRSEVV
REIFSCLQIPSKSDWNNLKGDIQRYGLYHAYRLAVAPTQSISYIQNATTS
LMPIVEPVEARVYGNSTTYYPMPYLSRENAIFFKSAYYMDMRKLIDLVSE
AQRHVDQGISTLLYVTNETSTRELVKLYIYAKNKGLKSLYYTRNKNLSVD
ECILCAI
>BDU_1075 nrdF, ribonucleoside-diphosphate reductase beta subunit
MRKNREAINWNRLNNGYTKMFWDQNIRQFWVDEEIPISDDKLVWNTLSVD
ERDVYEKVLGGLTLLDTEQGSVGMPRIALAIDNLDYKPILGFMGAMEHMH
AKSYSSIFSSLSNIDRIDYIFDWVKTYRNYQEKLELILGKYNNIHDRMSL
YQALCTSVFLETFLFYSGFFYPLYLAGQGKMVNSGEIINLILRDESVHGV
FVGLLAQEEFDKMTMKEQELAYKEMLLILEKLYSLEREYTKELYSCVGLE
SAVDVFVRYNADKALMNLGFDTKFNIKDTDVNPLVLNGLRTDTKTHDFFS
TKGNGYIKPMRVEPLHDDDFM
>BDU_1077 nrdI, ribonucleoprotein
MVYASKTGNIGRFISKTGLGNIFRIVTGDEIVEEPYVLLTYTIAFGKVPS
EVDKFLEHNFKLMIGVAGSGNKNWGDSFCNAVNLIKDKYGVPEILKFELS
GTSHDVKNFMERISDETLRVK
>BDU_404 nucA, endonuclease precursor
MKKKSKILIILYISILIGFLFLHQNPKIVNKIKEIASNYLEEIKNRFYRP
QIPIKLQEEYLLPQGYLTTQVLHKKYYSLGYAEHARQSEWVAYQLKREMV
ELALILVKEKKITRSKKFFEDPDIKGIAPKLSDYLHSGYDRGHIVSSADM
SFSKEAMRETYFLSNISPQKSSFNSGIWSKLEQKVRKWAISKEKIYIISA
GILTENQGFIGNNKILIPKNFYKIVLSLNNKSNNYEIVAFIIPNEKAKDT
DLKNYVVNVNSIEEKTKIDFFAKLDAKIKKIIKMQKNISSWELK
>BDU_370 pfs-1, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase
MILITSAMDEEAREIHQIIENKEEIKIDNYLGEKKIYKGEIEGHKIISLT
TGIGKVNAAMWNSYIIAKYKITHIINSGTAGGLQESSNIKISDIIISSQT
AFHDFNLTQFDYQIGQVPGFPQKFESDKTLLNKVISIIKDKFQNVNVHIG
LILTGDQFIEDEKQIEKIKNDFKDALAVEMESAAIAQVAYTFNIPFIVTR
SISDFPNNKNNHIDFNKFLQDASKNSAKMVRELIKSI
>BDU_373 pkcI, protein kinase C1 inhibitor
MEEILSDCIFCKIVKNEISCYKVYEDNLILAFLDINPLNIGHTLVIPKQH
SNDILDVNDELDGQLLGVCKKVALSLKKLDFNICQGVNIYSAIGSEAGQV
IFHTHFHVIPRFQGDNLGFKRNCSIELSGDEYLDLSKKISKNI
>BDU_546 prs, phosphoribosyl pyrophosphate synthetase
MSLLMKKSIGIIACPGGRVFAEKIMAELNTIFLDAENKVIEQISQTSNCS
KEDVLKFEGILSPFLEGLEFSNLRFDETMEIPVNFVKFANGEFKSEILKT
IRNKDIFIVQDVSNTYPVTVNNNEEVVMTVNDHLMNLMTTVDACMQAKAN
SVSVIVPSYPYSRQDKKHSREGLTASLFGRFLEELRVKHILTLDIHSKAI
ENVFRKSYFENLNASYEIFDALAELIDIRDSNLVVVSPDTGAVNRNKFFA
SNLKRPLALLYKERDYSKVTHNVTDSNISVTKLLGDVEGKNVFMSDDILA
TGGTFIKAVKLLKSMGAKKIICAVSLPFFNGDAIRYFDKAYEEGYFYKII
GTNAVYHDDKLLSKPWYYEANVAHLFAGAIFAIHNRVSLQRILDRSHDIQ
NLISKS
>BDU_419 purA, adenylosuccinate synthase
MAIYAVVGTQWGDEGKGKIIDFLSSKIDYVVRFNGGNNAGHTIVVNDKKF
IFNLLPSGVLQGAKCILGPSVVIDPLILIQELEVLKNNNIKTEIFISDKA
HIIMPYHIKFDELSEQKKGIHKIGTTKKGIGPCYADKINRIGIRTIDLLN
TEIFANKLKTNLEEKNQIIEKIYNDKPLDYDDILNTYKKYIEILKSLITN
TEKILHHAINSEKHILIEGAQGTMLDIEHGTFPFVTSSNTLITAAAGCGI
PISKIKQKIGIIKAFSSRVGSGPFVTEISNSIGDIIREKGQEYGSTTKRP
RRIGWLDLLTIKKAIALNELNHLALTKLDILNNIESLKICTAYEFQGKIY
DYIPTSCETIEKVRPIYKVFKGFKEDISNIKNYDDLPIEAREYIEFIEKE
VGIQISILSVGSEREKTIFRNQEWSNI
>BDU_420 purB, adenylosuccinate lyase
MEQYLNPLKSRYASKEMLYIFSPKFKYTTWRKLWYNLALVQQELGININN
DQLNELSKQIENIDFKLVEKYEKKFQHEVMAHLYAYADLVGEDAKKILHL
GVTSAYLMDNTDLIQIKEALLLIEKKLTEIIIILKQFSIKYKDLATLAYT
HLQEAQLTTLGKRSSLWLQSLIFDFRELKFILSNMCFRGVKGTVGNQSSF
KELFLSNFDKVKDLDINLAKKMGFEKVYKITGQTYDRKFDSSILNFLSNL
AQSAHKITNDIRFMQHLREIEENFEKYQIGSSAMPYKRNPIYSERVASLA
KFIISLQSSGGLIATTQWLERTLDDSACKRLNIPQAFLATDAILILLNQI
FSNIKVNERIVEKHVQTEMPFILTEDILMKATKNGGDRQILHEKIRTYAM
QVKENLYSGKNENNLIQLILNDKSFKLTSKDINEILNPNKNIGFASSQVE
DFIKEIIDPIIKNQ
>BDU_579 pyrG, CTP synthase
MWAFVLRIEFIWRVLIMDNLKILVITGGVISGIGKGVTSASIARLFKDNL
KITPIKCDGYLNTDPGTINPVEHGEVFVLDDGGEVDMDFGHYERFLNQNS
KSTWNITMGKIYKSILENERRGKYLGRTVQLIPHVTNEIKETILNIAREE
HSELLVIEIGGTVGDMENILFIETMRQIRYDIGIDNIAFVHLTYIPNPAG
INEQKSKPTQQSVKTLNKAGIFPDLIIARSSQLLTRQIRDKIAMFCNVDA
SCIVDNIDVATIYEIPISFYKQGLHKILGSKLKINVTPKVDGLEKLVNVI
KKNLLSPQKVVNIAICGKYTELGDSYASIFESLTHVSANLDILVKTTVID
GINFDEKMMEGVDGIVVPGGFGSRGYEGKIRAIKYARENNIPFLGICLGM
QLAVIEFARNVCGIFDADTEEVLSEDNAVLNSINPVIHLLSEQKELENKG
ATMRLGGYPVLLKKDTLAFKLYGHDMIIERFRHRYEVNNDYLDLFSKYGL
VVSGFSEDFQIVKIIEIPKNKFFVACQFHPELITRLESPSKLFVGLVKAC
L
>BDU_575 smbA, uridylate kinase
MIKIISLGGGIINPNHINTTYIKNLKNLIFQWIKKEHNRKVILITGGGKT
AREYQDAYKQINPKFKNHELDEIGIMATKLNATLISKAMQPFCINDIVSN
PTEDFQFKGQILVASGWKSGFSTDYITVKFAEKFNSNEIINLTNIDQIYD
KDPKKYNDAKGFKNITWNKLQNIVGKDWEPGSHLPFDPIATELALKLGIK
AYILNGTDLTNLQKVFDKNDDFLGTIVVK
>BDU_798 tdk, thymidine kinase
MGFYLNLVNGDTRSKLDNIVSISHFNFKDNSNLMLIIGPMGSGKTEYAAK
IYKDSLIIKNKSSEILASITRGLRNRANVFFIRNILDKKRFKNYPENVIP
YRGGGSDEIDGVDFASDSFDVGQLIEKNPEYGTFIIDETCFYDERLVFIV
NKIALDLNVLFILPTLLYNFRKEIFNNTARLLIEYADKICSLGAYCEHIN
CMDESFLTYRYYFYEGKEIAAPYFDPLLIVGGDEIVESAIYPNYATRCSK
HHYLVGREYFFTILKPFALLYIQGDRKFLEREIVDLKSNIVNSNFQKSLL
IEVGEKYDITILENVLKLPFLAERALITLSFEYNILSKEDFKEIVNRFSL
SKDYIQKVIVSREYKGIF
>BDU_16004 thyl, thymidylate synthase-complementing protein
MNFKIEKENLLNIEHKVLDKGFIKLVDFMGSDERIIQAARISYRGESIKR
EDRELIDYLIRNEHTSPLEQVVFTFYVKAPIFVARQWMRHRTARINEVSS
SYSLIREEFYVPLEENMNTHNVTDNQDNKKTECEFREEILNNLKENQKSS
YKLYQNMINHNISKEISRIVLPLSLYTEWYWQIDLNNLFHFIKLRSALNA
SKEVAEHSSKEMREYAKVLLEIIEKIVPIATKSFKNHILKGCKLSYEEIV
AIAGALDISKLKLDANALKRLQDKLNI
>BDU_800 tmk, thymidylate kinase
MTKILKNFYCIEGIDGSGKTSIIQKLQKICNNKMKYHFTKEPSTGIIGKL
IRKQLTNFKNPLRKVSLAHLYVADRYEHLYNIQNGIIAILNKNQTKVISD
RYLFSSIAYQGELGYKLNKDFPLPEKLFFIKTDPNIAFKRIQKNRTQADL
FEFEEAKFKEINSRYMEMFQIFNQLIDIVYIENSSEHDLEISARKIFDLI
KF
>BDU_21 udk, uridine kinase
MVKIIGISGGSGSGKTTIVNKISEVISEFVLISQDNYYKSVGDYEYEFLD
VNFDHPDAFDNNLFYKQLKKLKENQSINMPLYDFINHKRRDETIKIVPTP
IIIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLERDMSKRGRTLES
VIEQYLRTTRAGYYRFIEPTKEYADLIIPEGGHNDKALYVLSSFLKTLVK
DSSKFF


# Borrelia garinii High passage (300), PBi

>G1Mb28h10.r1_1 hypothetical protein
MGLFKIEANYIDIFNKEIYPASITIKNGYIVSIKKIDAILKEYVLPGFID
AHIHIESSFLIPSNFAHLVVQHGTVATISDPHEIANVNGIEGINFMINNS
KKTEFKIFFGAPSCVPALSSEFETSGHVLDDQDVDKLMQSNDIYYLSEVM
DFKGVINKDVGIINKINSALKRNKVVDGHAPGLSPYLTLKYASSGISTDH
ECSTIEDARYKLSLGMKIIIREGSAAKNFESLHPLISECSKEYCDSLMFC
FDDAHPNDILNGHINSIVARAIEYGHDFFDVLKIACINPVLHYKIPVGLL
RTGDPADFIITKDIKTFEIDKTYINGKLVFNDGISHIPLISEIPINNFNC
EQKSILDFKFSTKNKMIPIINCINNQIITHKTMIDSNLLAPDFQSNIAED
ILKIAVINRYENNSKISIGFIKNFGIRKGAIGSTVAHDSHNIIVVGTNDE
YLCKATNIIIENKGGLCALNNEKTIIIKLPISGLMSALPAKEIASQYVKL
NDFCKNVLGSQLD
>G1Mb28h10.r1_7 hypothetical protein
MKIKNIVNRLIFFLSIVLNSWGNELKINEPNENSQSNILIISATKTEIAE
INKIIQNKKSISIEKHIRKKNITIGKVFDHNIITIATGVGKINTAFWTSY
IISKYKISHIINAGVASGIYSNKNKFIKVGDVIISTETISYDFNLHRFGY
EIGHVPGHPKKFKANAALIRQASKIKINNITSYIGLIITGDQFMDHQNFQ
EIPEEFENAIAIDMESTAMAQVAYNFKIPFIIIRGISDIVNNENNYDDYK
KFLKKASTNSAKIVEKLIKLM
>NC_006156.1_430 hypothetical protein
MKIYLASPFFNEEQIKLRDEVLKFLEEFNLDIFSPEHHAVKKMGLLEKVD
YKFANRDIREKIREIDLKELVSSDIVLALVNYVDAGTAYERGFAFAKKIP
SIDFFKDKKDSDFYNLMYSDCNASFSNYKDLREGILTFKELWIKFKGDNE
SFRTFFDYLKAKLGDKLKKILTTLPVNEKCGC
>NC_006156.1_725 adenylyl cyclase, CyaB-type, putative
MLEIESKAFIPQKELKRIIKLANKKFKFIKEEIKTDIYYSNLKKIIRIRK
LNTLEKIVTFKKILDNNNAIEINKEVEFKIDNINNFLILIKELEFKKLYK
KIKKSLIYQTNNLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIHNII
NQFGLQENLETRSYFELLSLTNQSKK
>NC_006156.1_246 hypothetical protein
MKTLFFATTNENKINEVKNILDMPNLNLVVPKNFNIKETGTTFKENSLLK
AKALFAILNKNQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNE
KNQLILDLMKNEKNRKAYFICNISYISKDRQILNFEGIIKGEIALSLNDD
KNYGFGYDSIFLTKNNKKLSDLTLEEKNKISHRGIAFSKFKKFLLKSLFN
N
>NC_006156.1_822 hypothetical protein
MKIALSGKSGCGNTTVSSMIAKHYGLEFINYTFHDIARERNIPFSEFYEK
EIIGRDDYYWDMYLDKRLSLLSKKNNTVLASRLAIWISKSADLKIYLYAK
MEVRAERIMTREGGMYSDVLSSTFNRDENDKKRYLSIYNIDIDDYSSKTD
LVIDVTNINSNEVFELIRDEIDKRNLKN
>PBI300a20b10.r1_88 hypothetical protein
MNKEYKILDNGFLKLIDFIGDDKRIVDAARISYRGDSVKRKDEELIDYLI
RNGHTSPLEQVVFTFHVKAPIFIARQWMRHRTARINEASGCYSLARKEFY
IPLEEDLKRQISNNNQPERELNSLEKSLSDKIKHYQA
>NC_006156.1_418 adk, adenylate kinase
MGLVFLGPPGSGKGTISKIISNEFKYHHISTGDLFRENILNSTTLGKEIK
KIVEKGELVPDQITIKIVKDKIKAIKKNDNFILDGFPRNICQAEALDKFL
PNVKIINFLINEELVIKRLSGRRICKSCNNIFNIYTLATKKNGICDVCKG
DLYQREDDKEECLKTRLKEYKLQTKPLIEFYSKCSRLNNVDASVEIDEIK
KKIIKIMLKKN
>NC_006156.1_778 apt, adenine phosphoribosyltransferase
MKNKTEYYDQFIAKVPDFPKKGVLFYDITSVLLKPEVYTSLINEAYSFYN
LKKIDCIAVVESRGYLIGAPLSLKMQLPLVLIRKEGKLPREVFGEEYELE
YGFGKIEVHKDDVRMYSNILLIDDILATGGTLKSSAILLERAGGRVKDIF
CFIELCGINGRRILEDYDVNSLVRYN
>NC_006156.1_621 cdd, cytidine deaminase
MEKPKQEDINKAFYMAEKARNNSYSPYSKFKVGVCIKTKTNEFFIGTNVE
NASFGATCCAERSAISNMIAKIGVQTIDFLLLNTSPEAIPCAICLQVMAE
FFDQDTKIIITESKSFNENKMPTKIYTLKDLLKVPFDKKELHRVTQ
>NC_006156.1_129 cmk, cytidylate kinase
MIIAIDGPSASGKSSIARELGVKLGYKFISSGYLYRIITLIAQKFLMSSC
DFISEDRLLNLILENDISFNDSSFFLNGENVESQILNDKIDFQVSFYSSY
VGIRNIVNKKLREVVKFSNDNYIIEGRDITTIVFPESEFKIYLDASVKVR
ALRRYKQRNGNETLEELERTLKIRDDVDKRKQYGKLKLSKGVFYLDTSYK
GLDDVCNIIIEKFNLKKVRER
>NC_006156.1_238 dck, deoxyguanosine/deoxyadenosine kinase(I) subunit 2
MIVIEGLIGVGKTTLGNILSNELKVPFYSELNNDFTLAVLDKFYRDKSRW
AFPVQINFLNERFKLIKGVFRTKGGILDRSIYGDCVFASLLNCDGHISDE
EYKIYIDLLDNMLEHSQRPSLLIYLDCSIDEVERRIKNRNRSFEMNIPRD
YLEGLNRKYLKWYNEYSLSSKIKFSYDDINIFNEEDKNKVISLIRDKLVL
>PBI300d04e03.r1_22 guaA, GMP synthase
MNVRAILVLDFGSQYSQLIARRIREIGVYTKVIPYYTPLKEIKNMNIAGI
ILSGGPASVYAKDAPTLNMEIFNLKIPVLGICYGMQLIVKLFGGLVSKDY
KQEYGSSEIFLKNEKSLLFSELPNKFQIIMSHGDSIEKIPNNFKQLAFTK
NCIASISNEDQKIYGLQFHPEVTHSEFGDQILKNFVFKICQSQTNWSLES
NVETIVEKIKLKVGSKKVILGLSGGTDSLVCALLIKKAIKENLICVFVNT
GLLRKNEDKKILELKHQYDLNIKYIDASEKFLNYLKNISDPEEKRKIIGK
EFVNVFEKITLEDQNIEYLAQGTIYSDVIESKSKNNASSKIKSHHNVGGL
PDKMRLKLLEPLNEFFKDEIIQIGINLGIKKEALYRHPFPGPGLAIRIIG
EVTQEKINILQEAENILTEELFTNDLYYEIRQAFVVLLPVKSVGVMGDQR
TYEYTAVIRCVNTQDFMTAEWTELPYNFLRKVSSRIINEVRGINRVCYDI
SSKPPSTIEWE
>PBI300d04e03.r1_21 guaB, IMP dehydrogenase
MTNKIIKEALTFDDVSLIPRKSSILPSEVSLKTQLTKNISLNIPFLSSAM
DTVTESQMAIAIAKEGGIGIIHKNMSIEAQKKEIEKVKTYKVQKTININK
DINEQTTKMLLEKQHLEESKIYKNAERKEDFPNACKDLNSRLRVGAAVSI
DIDTLERVEELVKAHVDILVIDSAHGHSTRIIELVQTIKNKYPSLDLIAG
NIVTKEAALDLINVGADCLKVGIGPGSICTTRIVAGVGVPQITAICDVYE
VCKNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGVKESPSEEII
YNGKKFKSYVGMGSISGMKRGSKSRYFQLENNEPKKLVPEGIEGMVPYSG
KLEDILTQLKGGLMSGMGYLGANTISDLKINSKFVKISHSSLKESHPHDV
LNIP
>NC_006156.1_467 ndk, nucleoside-diphosphate kinase
MSMLLQKTLCIIKPDGVRRGLIGDVVARFERVGLKIVAAKMLIIDESLAK
KHYLYDDIVLRHSEAVWKSLIKFISNSPVFAFVVEGVESIEVVRKLCGAT
EPKLAIPGTIRGDFSYHSFRYSNEKGFSIYNVIHASANEVDAIREIPIWF
KDNEILNYKRDDECEHYYC
>NC_006156.1_412 nucA, endonuclease precursor
MKKRSKFFLYCYILCLAGFLFFSLNPKVLKQIKHKINDYLEIIENKYIKI
TKSIPIKESQLIPKGYLTTQIISKKHYTLGYAESARQSEWAAYPLKREMV
ELALTLLKSKKIKRSPKFFEDTNIKGIFPKLEDYFKSGYDRGHIVSSADM
SFSENAMKDTYFLSNMSPQKSEFNSGIWLKLEKLVREWAILKGYIYIISA
GILTENKGFIGKNKILIPKNFYKIVLAINNKNFYDIISFIIPNEKAKDLN
LKNYVVNVDLIEKKTKIDFFAKLDSKIKKNIKKIKTTHSWRFK
>NC_006156.1_370 pfs-1, 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative
MILIISAMQEEAEEINKMIDDREEVLLNHYLENKKIYKGKILGKDVISLT
TGIGKVNAATWSNQIISKYKITHIINSGSSGGIKENSNLKILDIIVSSET
AYYDFDLTKFGHKIGQVPNLPQKFKADEELLKKVVNIVENKLLNIDIHIG
LILTGDRFVDNEKSLETIKKNFKDALAVDMEGAAIAQVAYIFKIPFIIIR
SISDLPNNKDNHIDFNKFLKTSSINSSKMTKELIRLI
>NC_006156.1_589 pfs-2, 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative
MNNFLRKFFLFLLVFSNGYVAFSKNINVLIVTAMDSELEEINKLMSNKEE
IVLKEYGLNKKIVKGKLSNRNVMAIVCGVGKVNAGVWTSYILSKYNISHV
INYGVAGGVISDKYKDIKVGDIVVSSEIAYHDVDLTKFGYKMGQLMGLPQ
KFIANKNLVNKAKEAVKLKVRGSNAYSGLILTGDQFIDPIYIKKIIRDFK
DVIAVEMEGAAIGHVAHMLNVPFVVIRSISDIVNKEENEVEYSKFLKLAS
FNSAKVVQEILRIL
>NC_006156.1_374 pkcI, protein kinase C1 inhibitor
MYDCIFCKIVNKELPSYKVYEDDLVLAFLDVNPLTVGHTLVIPKEHSENL
LNMDDKFNERVLRVCKKISNALKRMNSSIYGGINIYSSLGAGAGQEIFHT
HFHVIPRFKNDGFGFKRGNKINLEVEKFKELSIQISMNI
>NC_006156.1_544 prs, phosphoribosyl pyrophosphate synthetase
MNLLKKKSIGIIACPGGRVFANKIIEELERIFINVENDIVDSICQDSKAL
KEEIFKIEKVLSPFLEGLSLSTFKSKEPLEIPVKFVKFANGEFKTEILKT
IRNKDIFIVQDVANTYEVEINSSEKIIMTVNDHIMNLMTTIDACMQAKAN
SVSVIIPSYPYSRQDKKHSRECLTASLIGRFLEELGIRHILTLDIHSKAI
ENVFRKVYFENLNVSYEIFKSLGDLIDIRDSNLVIVSPDTGAVSRNKFFA
SSLKSPLALLYKERDYSRVSNDVADSNISVTKLLGDVEGKNVFMSDDMLA
TGGTLIKAMKLLKSMGAKKIICGISLPFFNGDAIKYFDKAYEEGYFYKII
GTNAVCHNDELINKPWYHETNVAHLFANAIFAIYNKVGLQKILDRRDDIQ
KLITKG
>NC_006156.1_575 pyrG, CTP synthase
MKKNLKILVITGGVISGIGKGVTSASIARLFRYDFRVTPIKCDGYLNTDP
GTINPVEHGEVFVLDDGGEVDMDFGHYERFLNLNAKSSWNITMGKIYKKI
LENERKGKYLGRTVQLIPHVTDEIKSTIFQIASSENSEMLIIEIGGTVGD
MENILFIETVRQIRHEIGSGNIAFIHLTYVPSPAGINEQKSKPTQQSVKT
LNKAGIFPDLIIARSSQVLTDQIRKKVAMFCNVESNSIIDNIDVSTIYEI
PISFYKQGVHEILSSKLNIKVDPKIEELSKLVGVIKSNFFVPKKIINIAI
CGKYAELDDSYASIRESLVHVGANLDLLIKSTLIDSNDLNESYLKEFDGI
IVPGGFGGKGYEGKIIAIKYARENNIPFLGICLGLQLAVIEFARNVCGIL
DADTEENLLKDKPLKSPVIHLLPEQKGIKDKGATMRLGGYPVILKKNTIV
FNLYGQDRIIERFRHRYEVNNDYIDLFEKNGLVVSGFSSDFKIAKLIEIP
KNKFFVACQFHPELITRIENPAKLFLGLIKACI
>NC_006156.1_571 smbA, uridylate kinase
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGKV
AREYQDAYKKINPDFKVRELDEIGIMSTRLNAEFLCKVMNPLCKDKIVTN
PLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDVINITNVNQVYD
KDPKKFKNATAFKKLNWKQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLT
LYIVNGNNIENLEKVFNKNNDFLGTVIVK
>NC_006156.1_793 tdk, thymidine kinase
MGFCLDFANKEDAKLSNIVSISHFDFKVKINLILVVGPMGSGKTEYAAKI
YKDSLIVRKKSFKVLGNVIKGNRSRVNVFFIRNFFDKRRFQDYPENVIPY
RGGGKDKIDEIGFASNSFDIENLIASNPSCGTFIIDEACFYDERLIFVLN
KISLNENILFILPTLLYNFRKESFNDTARLLVEYSDKIYKLGAYCEHIDC
MEESFFSYRYYFYNNKEIPAPYFDPLFIVGGDKGIESAVYPNYATRCSMH
HYLVGKEYFFSFLKPFALLYSQGDKKFLENEIVALSTDVENSNFVNSLDN
EKACELRAEILRNILELPFLAERALITLFSEYSILSKDNFKDLVFKFSLN
KDYINKIFFSKEGKEFF
>NC_006156.1_796 tmk, thymidylate kinase
MIKILKNFYCIEGIDGSGKTSISNKLKTLCNDESRYYFTKEPSNGIIGKM
IKEQLMNFKNPLKESTFAYLYAADRHDHLYKKGGILEILNTKTKKIITDR
YLFSSIAYQGNLGYELNKNFPLPEKVFFIKTDPNIAYERIQKNRTQSDLF
ELEKYKTFEQIALKYLKIFKELEKKINVIYINNSIKDNLDETAKKIFNLI
KF
>NC_006156.1_15 udk, uridine kinase
MAKIIGISGGSGSGKTTVVSKISEFIPEFVLISQDNYYKSVGDYEYEFSK
VNFDHPDAFDNNLFYEHLKNLKKNSPIDMPLYDFINHKRQLKTVMVVPTP
VIIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLKRDISKRGRTLES
VIDQYLNTTRWGYYRFIEPTKEYADLIIPEGGHNDKALYVLSTFLKSLSK
EGLDFV


# Borrelia garinii, PBi

>BG0434 hypothetical protein
MKIYLASPFFNEEQIKLRDEVLKFLEEFNLDIFSPEHHAVKKMGLLEKVD
YKFANRDIREKIREIDLKELVSSDIVLALVNYVDAGTAYERGFAFAKKIP
SIDFFKDKKDSDFYNLMYSDCNASFSNYKDLREGILTFKELWIKFKGDNE
SFRTFFDYLKAKLGDKLKKILTTLPVNEKCGC
>BG0745 adenylyl cyclase, CyaB-type, putative
MLEIESKAFIPQKELKRIIKLANKKFKFIKEEIKTDIYYSNLKKIIRIRK
LNTLEKIVTFKKILDNNNAIEINKEVEFKIDNINNFLILIKELEFKKLYK
KIKKSLIYQTNNLNVEINEIKNLGFFLEIEKIINNQNDIDLAKKEIHNII
NQFGLQENLETRSYFELLSLTNQSKK
>BG0844 conserved hypothetical protein
MKIALSGKSGCGNTTVSSMIAKHYGLEFINYTFHDIARERNIPFSEFYEK
EIIGRDDYYWDMYLDKRLSLLSKKNNTVLASRLAIWISKSADLKIYLYAK
MEVRAERIMTREGGMYSDVLSSTFNRDENDKKRYLSIYNIDIDDYSSKTD
LVIDVTNINSNEVFELIRDEIDKRNLKN
>BG0249 conserved hypothetical protein
MKTLFFATTNENKINEVKNILDMPNLNLVVPKNFNIKETGTTFKENSLLK
AKALFAILNKNQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNE
KNQLILDLMKNEKNRKAYFICNISYISKDRQILNFEGIIKGEIALSLNDD
KNYGFGYDSIFLTKNNKKLSDLTLEEKNKISHRGIAFSKFKKFLLKSLFN
N
>gid:19082  BGP035  hypothetical protein
MKIKNIVNRLIFFLSIVLNSWGNELKINEPNENSQSNILIISATKTEIAE
INKIIQNKKSISIEKHIRKKNITIGKVFDHNIITIATGVGKINTAFWTSY
IISKYKISHIINAGVASGIYSNKNKFIKVGDVIISTETISYDFNLHRFGY
EIGHVPGHPKKFKANAALIRQASKIKINNITSYIGLIITGDQFMDHQNFQ
EIPEEFENAIAIDMESTAMAQVAYNFKIPFIIIRGISDIVNNENNYDDYK
KFLKKASTNSAKIVEKLIKLM
>BG0420 adk, adenylate kinase
MGLVFLGPPGSGKGTISKIISNEFKYHHISTGDLFRENILNSTTLGKEIK
KIVEKGELVPDQITIKIVKDKIKAIKKNDNFILDGFPRNICQAEALDKFL
PNVKIINFLINEELVIKRLSGRRICKSCNNIFNIYTLATKKNGICDVCKG
DLYQREDDKEECLKTRLKEYKLQTKPLIEFYSKCSRLNNVDASVEIDEIK
KKIIKIMLKKN
>BG0801 apt, adenine phosphoribosyltransferase
MKNKTEYYDQFIAKVPDFPKKGVLFYDITSVLLKPEVYTSLINEAYSFYN
LKKIDCIAVVESRGYLIGAPLSLKMQLPLVLIRKEGKLPREVFGEEYELE
YGFGKIEVHKDDVRMYSNILLIDDILATGGTLKSSAILLERAGGRVKDIF
CFIELCGINGRRILEDYDVNSLVRYN
>BG0636 cdd, cytidine deaminase
MEKPKQEDINKAFYMAEKARNNSYSPYSKFKVGVCIKTKTNEFFIGTNVE
NASFGATCCAERSAISNMIAKIGVQTIDFLLLNTSPEAIPCAICLQVMAE
FFDQDTKIIITESKSFNENKMPTKIYTLKDLLKVPFDKKELHRVTQ
>BG0130 cmk, cytidylate kinase
MIIAIDGPSASGKSSIARELGVKLGYKFISSGYLYRIITLIAQKFLMSSC
DFISEDRLLNLILENDISFNDSSFFLNGENVESQILNDKIDFQVSFYSSY
VGIRNIVNKKLREVVKFSNDNYIIEGRDITTIVFPESEFKIYLDASVKVR
ALRRYKQRNGNETLEELERTLKIRDDVDKRKQYGKLKLSKGVFYLDTSYK
GLDDVCNIIIEKFNLKKVRER
>BG0242 dck, deoxyguanosine/deoxyadenosine kinase(I) subunit 2
MIVIEGLIGVGKTTLGNILSNELKVPFYSELNNDFTLAVLDKFYRDKSRW
AFPVQINFLNERFKLIKGVFRTKGGILDRSIYGDCVFASLLNCDGHISDE
EYKIYIDLLDNMLEHSQRPSLLIYLDCSIDEVERRIKNRNRSFEMNIPRD
YLEGLNRKYLKWYNEYSLSSKIKFSYDDINIFNEEDKNKVISLIRDKLVL
>BGB17 guaA, GMP synthase
MKYALIRKLLFVLRTYMMNVRAILVLDFGSQYSQLIARRIREIGVYTKVI
PYYTPLKEIKNMNIAGIILSGGPASVYAKDAPTLNMEIFNLKIPVLGICY
GMQLIVKLFGGLVSKDYKQEYGSSEIFLKNEKSLLFSELPNKFQIIMSHG
DSIEKIPNNFKQLAFTKNCIASISNEDQKIYGLQFHPEVTHSEFGDQILK
NFVFKICQSQTNWSLESNVETIVEKIKLKVGSKKVILGLSGGTDSLVCAL
LIKKAIKENLICVFVNTGLLRKNEDKKILELKHQYDLNIKYIDASEKFLN
YLKNISDPEEKRKIIGKEFVNVFEKITLEDQNIEYLAQGTIYSDVIESKS
KNNASSKIKSHHNVGGLPDKMRLKLLEPLNEFFKDEIIQIGINLGIKKEA
LYRHPFPGPGLAIRIIGEVTQEKINILQEAENILTEELFTNDLYYEIRQA
FVVLLPVKSVGVMGDQRTYEYTAVIRCVNTQDFMTAEWTELPYNFLRKVS
SRIINEVRGINRVCYDISSKPPSTIEWE
>BGB16 guaB, IMP dehydrogenase
MTNKIIKEALTFDDVSLIPRKSSILPSEVSLKTQLTKNISLNIPFLSSAM
DTVTESQMAIAIAKEGGIGIIHKNMSIEAQKKEIEKVKTYKVQKTININK
DINEQTTKMLLEKQHLEESKIYKNAERKEDFPNACKDLNSRLRVGAAVSI
DIDTLERVEELVKAHVDILVIDSAHGHSTRIIELVQTIKNKYPSLDLIAG
NIVTKEAALDLINVGADCLKVGIGPGSICTTRIVAGVGVPQITAICDVYE
VCKNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGVKESPSEEII
YNGKKFKSYVGMGSISGMKRGSKSRYFQLENNEPKKLVPEGIEGMVPYSG
KLEDILTQLKGGLMSGMGYLGANTISDLKINSKFVKISHSSLKESHPHDV
LNIP
>BG0476 ndk, nucleoside-diphosphate kinase
MSMLLQKTLCIIKPDGVRRGLIGDVVARFERVGLKIVAAKMLIIDESLAK
KHYLYDDIVLRHSEAVWKSLIKFISNSPVFAFVVEGVESIEVVRKLCGAT
EPKLAIPGTIRGDFSYHSFRYSNEKGFSIYNVIHASANEVDAIREIPIWF
KDNEILNYKRDDECEHYYC
>BG0412 nucA, endonuclease precursor
MKKRSKFFLYCYILCLAGFLFFSLNPKVLKQIKHKINDYLEIIENKYIKI
TKSIPIKESQLIPKGYLTTQIISKKHYTLGYAESARQSEWAAYPLKREMV
ELALTLLKSKKIKRSPKFFEDTNIKGIFPKLEDYFKSGYDRGHIVSSADM
SFSENAMKDTYFLSNMSPQKSEFNSGIWLKLEKLVREWAILKGYIYIISA
GILTENKGFIGKNKILIPKNFYKIVLAINNKNFYDIISFIIPNEKAKDLN
LKNYVVNVDLIEKKTKIDFFAKLDSKIKKNIKKIKTTHSWRFK
>BG0374 pfs-1, 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative
MILIISAMQEEAEEINKMIDDREEVLLNHYLENKKIYKGKILGKDVISLT
TGIGKVNAATWSNQIISKYKITHIINSGSSGGIKENSNLKILDIIVSSET
AYYDFDLTKFGHKIGQVPNLPQKFKADEELLKKVVNIVENKLLNIDIHIG
LILTGDRFVDNEKSLETIKKNFKDALAVDMEGAAIAQVAYIFKIPFIIIR
SISDLPNNKDNHIDFNKFLKTSSINSSKMTKELIRLI
>BG0601 pfs-2, 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative
MNNFLRKFFLFLLVFSNGYVAFSKNINVLIVTAMDSELEEINKLMSNKEE
IVLKEYGLNKKIVKGKLSNRNVMAIVCGVGKVNAGVWTSYILSKYNISHV
INYGVAGGVISDKYKDIKVGDIVVSSEIAYHDVDLTKFGYKMGQLMGLPQ
KFIANKNLVNKAKEAVKLKVRGSNAYSGLILTGDQFIDPIYIKKIIRDFK
DVIAVEMEGAAIGHVAHMLNVPFVVIRSISDIVNKEENEVEYSKFLKLAS
FNSAKVVQEILRIL
>BG0378 pkcI, protein kinase C1 inhibitor
MYDCIFCKIVNKELPSYKVYEDDLVLAFLDVNPLTVGHTLVIPKEHSENL
LNMDDKFNERVLRVCKKISNALKRMNSSIYGGINIYSSLGAGAGQEIFHT
HFHVIPRFKNDGFGFKRGNKINLEVEKFKELSIQISMNI
>BG0554 prs, phosphoribosyl pyrophosphate synthetase
MNLLKKKSIGIIACPGGRVFANKIIEELERIFINVENDIVDSICQDSKAL
KEEIFKIEKVLSPFLEGLSLSTFKSKEPLEIPVKFVKFANGEFKTEILKT
IRNKDIFIVQDVANTYEVEINSSEKIIMTVNDHIMNLMTTIDACMQAKAN
SVSVIIPSYPYSRQDKKHSRECLTASLIGRFLEELGIRHILTLDIHSKAI
ENVFRKVYFENLNVSYEIFKSLGDLIDIRDSNLVIVSPDTGAVSRNKFFA
SSLKSPLALLYKERDYSRVSNDVADSNISVTKLLGDVEGKNVFMSDDMLA
TGGTLIKAMKLLKSMGAKKIICGISLPFFNGDAIKYFDKAYEEGYFYKII
GTNAVCHNDELINKPWYHETNVAHLFANAIFAIYNKVGLQKILDRRDDIQ
KLITKG
>BG0586 pyrG, CTP synthase
MKKNLKILVITGGVISGIGKGVTSASIARLFRYDFRVTPIKCDGYLNTDP
GTINPVEHGEVFVLDDGGEVDMDFGHYERFLNLNAKSSWNITMGKIYKKI
LENERKGKYLGRTVQLIPHVTDEIKSTIFQIASSENSEMLIIEIGGTVGD
MENILFIETVRQIRHEIGSGNIAFIHLTYVPSPAGINEQKSKPTQQSVKT
LNKAGIFPDLIIARSSQVLTDQIRKKVAMFCNVESNSIIDNIDVSTIYEI
PISFYKQGVHEILSSKLNIKVDPKIEELSKLVGVIKSNFFVPKKIINIAI
CGKYAELDDSYASIRESLVHVGANLDLLIKSTLIDSNDLNESYLKEFDGI
IVPGGFGGKGYEGKIIAIKYARENNIPFLGICLGLQLAVIEFARNVCGIL
DADTEENLLKDKPLKSPVIHLLPEQKGIKDKGATMRLGGYPVILKKNTIV
FNLYGQDRIIERFRHRYEVNNDYIDLFEKNGLVVSGFSSDFKIAKLIEIP
KNKFFVACQFHPELITRIENPAKLFLGLIKACI
>BG0582 smbA, uridylate kinase
MLEIISLGGGVINSNQINIEFIKNFKNFVFKWLLENEKRKIILIVGGGKV
AREYQDAYKKINPDFKVRELDEIGIMSTRLNAEFLCKVMNPLCKDKIVTN
PLKNFSFKGKILIASGWKSGFSTDYIAVKFAEKFNKKDVINITNVNQVYD
KDPKKFKNATAFKKLNWKQLQNIVGQKWNPGLNLPFDPIATKLSSKLGLT
LYIVNGNNIENLEKVFNKNNDFLGTVIVK
>BG0816 tdk, thymidine kinase
MGFCLDFANKEDAKLSNIVSISHFDFKVKINLILVVGPMGSGKTEYAAKI
YKDSLIVRKKSFKVLGNVIKGNRSRVNVFFIRNFFDKRRFQDYPENVIPY
RGGGKDKIDEIGFASNSFDIENLIASNPSCGTFIIDEACFYDERLIFVLN
KISLNENILFILPTLLYNFRKESFNDTARLLVEYSDKIYKLGAYCEHIDC
MEESFFSYRYYFYNNKEIPAPYFDPLFIVGGDKGIESAVYPNYATRCSMH
HYLVGKEYFFSFLKPFALLYSQGDKKFLENEIVALSTDVENSNFVNSLDN
EKACELRAEILRNILELPFLAERALITLFSEYSILSKDNFKDLVFKFSLN
KDYINKIFFSKEGKEFF
>BG0819 tmk, thymidylate kinase
MIKILKNFYCIEGIDGSGKTSISNKLKTLCNDESRYYFTKEPSNGIIGKM
IKEQLMNFKNPLKESTFAYLYAADRHDHLYKKGGILEILNTKTKKIITDR
YLFSSIAYQGNLGYELNKNFPLPEKVFFIKTDPNIAYERIQKNRTQSDLF
ELEKYKTFEQIALKYLKIFKELEKKINVIYINNSIKDNLDETAKKIFNLI
KF
>BG0015 udk, uridine kinase
MAKIIGISGGSGSGKTTVVSKISEFIPEFVLISQDNYYKSVGDYEYEFSK
VNFDHPDAFDNNLFYEHLKNLKKNSPIDMPLYDFINHKRQLKTVMVVPTP
VIIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLKRDISKRGRTLES
VIDQYLNTTRWGYYRFIEPTKEYADLIIPEGGHNDKALYVLSTFLKSLSK
EGLDFV


# Borrelia hermsii DAH, DAH

>BH0421C adenylosuccinate lyase
MDQYINPLKSRYASKAMLYIFSPKFKYTTWRKLWYNLALVQKELGIDISN
NQLNNLSKHIEDIDFELVEKYEAKFKHEVMAHLYAYADLAGDDARKILHL
GVTSAYLMDNTDLIQIKEALLLIESKLIKLIKTLREFSIKHKDLATLAYT
HLQEAQLTTLGKRSSLWLQSLIFDFQELKFIMSNMCFRGVKGTIGNQNSF
KELFASNFEKAKALDINLAKKMGFDKVYKMTSQTYDRKFDSSILNFLSNL
AQSAHKITNDIRFMQHLKELEEHFAEHQIGSSAMPYKKNPIYSERVASLA
KFTMSLQSSGGFIAATQWLERTLDDSACKRLNIPQAFLATDAALILLDKI
FNNIRVNKKIIENHVKTEMPFILTEDILMKATKNGGDRQILHEKIRIYSM
QVRENLYSGATENGLIKLILNDKSFRLTSKDIDEILNPNENIGFASYQVE
DFIKEIIDPILKNK
>BH0544 ribose-phosphate pyrophosphokinase
MSLLIKKSIGIIACPGGRVFADKIMEELKKIFLDTESKVIEKISQTSHCL
KEDVLKLEGILSPFLEGFGFSNSRFDEAMEIPVSFVKFANGEFKAEILKT
IRNKDIFIVQDVSNTYPVNVNNNEKVVMTINDHLMNLMTTIDACKQAKAN
SVSVIVPSYPYSRQDKKHSREGLTASLVGRFLEELGVKHILTLDIHSKAI
ENVFRKTYFENLNASYEIFDALAELIDIRDSNLVVVSPDTGAVNRNKFFA
SSLKRPLALLYKERDYSKVTHNVNDSNISVTKLLGDVEGKNVFMSDDMLA
TGGTFIKAVKLLKSMGAKKIICAISLPFFNGNAIRYFDKAYEEGYFYKII
GTNAVYHDDRLISKPWYYEANVAHLFAGAIFAIHNRVSLQKILDRSHDIQ
ALISKS
>BH0777 adenine phosphoribosyltransferase
MEISMKDKTEYYDKFIMRVPNFPKEGILFYDITNVLLQAEAYKSLMEDAH
AFYASRKIDCIAAIESRGYLIGSPLALKMGLPLLLIRKAGKLPRQVLREE
YELEYGFSSIEIHKDDVKQHSNILLVDDILATGGTLKAAAMLLKKAGGVV
SDIFCFIELVKMNGRDILREYSLNSLVRYF
>BH0128 cytidylate kinase
MIIAIDGPSASGKSSIAKALGSRLGFKFISSGYFYRIITLIAQKFTLNEY
DLLSESKILELVLQNDIKFNGVDFLLNGVNVTSHILNERIDLQVSLYSSY
IGVRNIVNKKLREIVKLKDDNYIIEGRDITTVVFPEAKVKIYLDASVKVR
ALRRYNQRDDDITLNELEQALERRDEIDQNKEYGKLKLAKEVFYIDTSYK
CLDDVCDIIIKTFNLKKK
>BH0421A hypoxanthine-guanine phosphoribosyltransferase
MDEEISTLFTEEKIKSKIKELAQKIRNYYKDKSNVVFISLLKGSFMFFAD
ITREIGLNVKIDFLQVSSYKNKTHSSLNVLIKKDIDIDIKDSYVIIFDDI
IDTGLTYDKIITYLKTKNPKEIKICTLFNKPSRRLIELKIDYAGFEIEND
FIVGYGIDFNEKHRTLKDVAKINK
>BH0375 5'-methylthioadenosine nucleosidase
MILITSAMDEESTEINKIIENKEEVILDEYSGGKKIYKGEIAGHKVISLT
TGIGKVNAAMWNSYIISRYKITHIINSGTAGGIKESTNLKITDIIVSSET
AFHDFNLTKFGHKIGQVPGFPQKFKADENLLSKIINITQDKFKNINVHIG
LILTGDQFIGDEKQLEEIKNNFADALAVEMESAAVAQVAYTFKIPFIIIR
SISDLLNIKDNHIDFNKFLQDASMNSAKMVRELIKLI
>BH0247 nucleoside-triphosphatase
MKTLFFATTNINKINEVKQILDIPNIKIEIPKNFDVKETGKTFKENSLIK
AKALFESLGRKHPVFSEDSGLCIEALNLEPGIYSKRYDQYKLGKKLGTKE
KNHFIIDLMKDKENRAAYFICIVSHIAKDGTITNFEGIFNGTIALDIDCC
KKNGFGYDPIFLTTNNKRLSELNLEEKNKISHRGIAFTKFKKFLMQSLD
>BH0793 thymidylate kinase
MLKTSKEIIFVNKILKNFYCIEGIDGSGKTSIIQKLQKLCNNKLKYHFTK
EPSQGIIGKFIRKQLTNLKNPLRRVSLAHLYAADRYEHLYNTKNGILEIL
NKGKTKVITDRYLFSSIVYQGELGYKLNRDFPLPEKLFFIKTDPSIAYKR
IQENRIQADLFEFEEAKFKDISSRYTEMLKIFDDLIDIVYIENLTKEDLE
TSTIKIFDLIKF
>BH0618 cytidine deaminase
MEHSEQNAIEKAFQMAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNVE
NASFGATRCAEQAAMMNMISSVGTQEIDFILIATTPASVPCAICRQVMSE
FFEENTKILITDPNQFNATKTISQTYTLNDLLKVPFNKKELSRIFKANQE
T
>BH0571 uridylate kinase
MIKIISLGGGIINPDKINIEYIKNLRSFIFKWVQGNDKRKIILITGGGKT
AREYQDAYKQINPNFKNHELDEIGIMATKLNAKLISKVMQPLCIDNIVSD
PTQDFHFKGQILIASGWKAGFSTDYITVKFAEKFKSDEIINLTNVDQIYD
KDPKKFDDAKGLKNITWNELQDIVGKNWEPGSNLPFDPIATKLALKLNLK
AYVLNGTDLQNLKKVFDKNDDFLGTIVVK
>BH0791 thymidine kinase
MSFYLKLVSGDTESKLDNIVSISHFDFQDNLNLMLIIGPMGSGKTEYAAK
IYKDSLIIKNKSPKVLNSITKGRRNRANVFFIRNILDKKRFKNYPLNVIP
YRGGGSDRVDGVDFAGSSFDVGQLIDENPEYGTFIIDETCFYDERLVFIL
NKIALDSNVLFILPTLLYNFRKEMFNNTAKLLIEYSDKICRLGAYCEHVD
CMDESFLTYRYYFYGGKEIAAPYFDPLLIVGGDEIVESAIYPNYATRCSR
HHYLVGREYFFTVLKPFALLYAQGDKKLLEREIVDLSSNARNANFENSLL
IESRGRYDIAVLENLLKLPFLAERALITLSLECNILSKRNLKELIDKFSL
SKDYIQKVIVSKEHKWIF
>BH0723 adenylate cyclase
MFEIELKAFIPKNKLKKILKLANQKFKFIKEEIKNDTYYSNTEKIIRIRK
FNTSEEIVTFKIQSLENDIEINREIEFKVDQINNFIFFLEEMNFKILYKK
IKKSLIYQKGNLNIEINDIENLGFYLEIEKIIYDKNELSLAKTEIYETIK
EFKLQNNIEKKSYFELILANQFKG
>BH0417 adenylate kinase
MKLVFLGPPGSGKGTIAKILSNKLNYYHISTGDLFRENISNATPLGKEIK
QIVENGQLVPDSITIKIVEDKINTLENKDNFILDGFPRNINQAKALDKFL
KNIQIINFLLDEEILIKRLSGRRICKSCGGIFNIYTLPTKEKEICDLCKG
ILYQRKDDTEGSLKVRLQEYHLQTKPLTDFYSKSNRLNNINASKDIDEVE
KSLMEIISKS
>BH0421B adenylosuccinate synthetase
MSIYAVIGTQWGDEGKGKIIDFLSSKADYVVRFNGGNNAGHTIVVNNKKF
IFNLLPSGVLQGAKCILGPGIVIDPLILIKELETLKHNNIKTEIFISDKA
HIIMPYHIKLDELSEQKKGTYKIGTTKRGIGPCYADKINRTGIRATDLLN
METFERKLKINLDEKNEIIEKIYNDKPFNYDDILSKYKEYIAILQSAITN
TEAILNHAINSGKTILIEGAQGTMLDIEHGTFPFVTSSNTLITAATGCGI
PISKIKQKIGIIKAFSSRVGSGPFVTEILEPIGDKIREKGQEYGSTTKRP
RRIGWLDLLTIKKSINLNELNHLVLTKLDILNDIEELKICTAYEFQGKIY
DYIPASCEILEKAKPIYKVFKGFKQDIRNISYYDDLPIEAREYIEFIERE
VGVQISMLSLGAEREKTIFRNKEWINI
>BH0819 cytidylate kinase
MRIAVSGKSGCGNTTISGMLAKYYGLKLVNYTFHDIAREKNMPFDMFYEK
EIIGRNDHYWDEYLDGKLLELSKEDNTVLASRLAIWLSKNADLKIYLYAK
IEIRAERIINREGGMYSDILRSTFNRDSNDSKRYLSVYNIDIDNYLDVAD
FIVDTTDRSANKVFELIKDEIEKRKLYIK
>BH0239 deoxyguanosine kinase
MEAILVIVIEGLIGAGKTTLGHVLSKEFNIPFYSELNNEFTLFMLDKFYK
DKSRWAFSVQINFLNERFKLIKAIFKTKGGILDRSIYGDRVFASLLNESG
YISNAECRIYFDLLDNMLEHSQRPVLMIYLDCSVDEAERRIKNRNRSFET
GIPREYLEGLNEKYLSWYDSYNLSPKLKFDYDSMDIFDDEHKSKLIAFIK
EKLVI
>BH0379 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
MEKILSDCIFCKIVKNEMSCYKVYEDELVLAFLDINPLNIGHTLVIPKQH
SNDALGMSDEINGQILKVCKRIALSLKKLDLNICKGVNIYSAIGSDAGQV
IFHTHFHVIPRFRGDNLGFKRGSNIELSGDELLDLSEKISQNI
>BH0735B hypothetical protein
MTRNNNDNLEQDFKQSLVHSNSKLKEFTKNIYKNIFREEIKKNVYSAVLG
LVITTISRTNFFKTISAKLTETSTMPEIRGKVYLKMNTAIISNIINMKKM
QKESLNHKKVKINSAKYIKIYKIINKDTY
>BH0411 endonuclease
MKKKLKILLCFYILILLGFLFLYQNPKILNNIKEIASNYLEKLKDKIYGP
EIPTELKEEYLLPKGYLTTQVLHKKYYSLGYAESARQSEWVAYQLKREMV
ELALTLLREKKITRSKKFFEDKDIKGISPKLSDYIRSGYDRGHIVSSADM
SFSKDAMLDTYFLSNISPQQREFNSGIWLKLERLVRKWAILKEKIYIVSA
GILTENKGFIGKNKILIPKNFYKIVLSLNNNNSYDILAFIIPNEKAQDLE
LRNYVVNVNLIEDKTKIDFFAKLDAGIKKVIKMKKDLYSWEFK
>BH0575 CTP synthase
MFLSIDIGCLNLFFWRVLMIDNLKILVVTGGVISGIGKGVTSASIARLFK
DNLRITPIKCDGYLNTDPGTINPVEHGEVFVLDDGGEVDMDFGHYERFLN
LNSKSNWNITMGKIYKNILENERHGKYLGRTVQLIPHVTDEIRDTIFKIA
KEECSELLVIEIGGTVGDMENILFIETMRQIRYEIGSDNIAFVHLTYIPN
PAGINEQKSKPTQQSVKTLNKAGIFPDLIIARSSQLLTKQIRQKIAMFCN
VDAESIVDNTDVSTIYEIPISFYKQGLHEILGSKLKINVKPKVDGLERLV
GIIKRNFASPRKVVNIAICGKYTELGDSYASIFESLTHVSANLDLLVKTI
VIDSTNFDEGMLKGIDGIVVPGGFGGRGYEGKMRAIKYARENNIPFLGIC
LGMQLAVIEFARNVCGILDADTEETLFEGNSAFSSISPVIHLLPEQKELK
DKGATMRLGGYPVLLKKDTLAFKLYGSEMIVERFRHRYEVNNDYLDLFNK
HGFVVSGFSEDSRIVKIMEIPKNKFFVACQFHPELITRLESPSKLFVGLV
KACL
>BH0015 uridine kinase
MVKIIGIAGGSGSGKTTIVNKISEVIPEFVLISQDNYYKSVGDYEYEFLD
VNFDHPDAFDNNLFYKQLKKIKENKLIHMPLYDFINHRRKDETVEIVPTP
VVIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLERDMSKRGRTLES
VIEQYLSTTRAGYYRFIEPTKEYADLIIPEGGHNDKALYVLSSFLRTLGK
EGADFF
>BH0463 nucleoside diphosphate kinase
MSTLIQKTLCIIKPDGVRRGLIGNVISRFEKAGLKIVAAKMTLVNRAMAE
IHYLYDDIAVRHGEFVWRSLIDFIISSPVFVFVIEGVEAVEVVRKFCGST
EPKVAALGTIRGDFAYHSFNYANEKKFAVYNVIHASASVDDALREIPIWF
KEDEILTYKRNDELEHYYG


# Borrelia recurrentis A1, A1

>BRE_1048 thymidylate synthase protein
MHDHVDAAEEVLDREYKVLDKGFLRLIDYMGSDERIVNSARVSYRDSKAK
RDSAALIDYLIRNEHTSPFEQVVFTFHVKAPIFVARQWMRHRTSRINEVS
GRYSLMREEFYVPLREDIKTQSLINKQGRSDEEIDIDVAISFLDGLDESY
KNAYKIYDDMIKKDVSRELARITLPLSLYTEWYWQIDLNNLFRFIKLRSS
GHAQKEIREYANVLLDIVNLVVPLATSSFKKHVLEGVMLSSEEVCEIRKA
LDLTKLNLSQKSLDRLKEKLNL
>BRE_829 cytidylate kinase
MRIAISSKSGCGNTTVSSMLAKYYGLKLINYTFHDIAREKNIPFDTFYEK
EIMGRNDYYWDEYLDSKLLKLSKEDNTILASRLAIWLSKDADLKIYLYAK
IEIRAERIINREGGMYSDILVSTFNRDFNDSKRYLSVYNINIDNYLDVAD
FIVDTTDQSANKVFELIKNEIEKRNLYVK
>BRE_247 rdgB/HAM1 protein
MKTLFFATSNINKINEVKQILDIPKIKIEIPQNFDIKETGKTFKENSLLK
AKALFKILNNKQPVFSEDSGLCIEALNMEPGIYSKRYDQYKLGKKLDNNE
KNHLIIDLMREQNNRTAYFICVISYIDVDGTINNFEGMLKGTIALNIDYY
QKNGFGYNPIFLTTNNKRLSELNLEEKNKISHRGIAFDKFKKFLMQFLD
>BRE_314 uncharacterized conserved protein
MIIIFLFLFSISNLYSFLEFGKDEKFYLIDDFGEIKNDTLNIGIKLRALD
THFSIFSNNYKVLYSKNKINEYDKSVLIIFDKDLNFNLEFFGDFIYKDDK
VFLMDNKNFDIVVVDQYNRQIINPLFVIKNRNNLNIISSFFVSELFLKSK
DNIVFLLKENVDLDLELGNYTLVLNFLKRDVAKESRILTGIYYFEVLLNN
NSVFRIDFQSIYLNGNSYVVSGNKNYNLNVFDLKKNNGSIKIDNLEFTNG
SNEIKIKYGDVYNVENSLTYRFTLNG
>BRE_1109 inosine-5'-monophosphate dehydrogenase
MMDKIVKEALTFDDVSLIPRKSSILPSDVNLKTRLTKNIYLNIPFLSSAM
DTVTESRMAIAVAKEGGIGVIHKNITIEKQRKEVEIVKSYHRNGIIRNLI
TINEDTSIKEARRLIVKHNISALPVTDHAGKILGLVTSRDIKYIADDNIP
VINAMTKKLITAKEDITLSEAKEILFKHKIEKLLIVDESNSLRGLITCKD
IDHVEHQEYFPNACKDMNDRLRVGAAVSTDVDTLERVEELVKADVDVVVV
DSAHGHSTKVIEIVRKIKSKYPNLDVIAGNIVTKEAAFDLIDAGADCLKV
GIGPGSICTTRIVAGVGVPQLTAINDVFEACKDTNICIIADGGIRFSGDI
VKAIAAGADSVMIGNLFAGAHESPSEEVMYNGKKFKIYVGMGSLAAMARG
SKSRYFQFESKDSSGKLVPEGIEGMVPYVGKVKDIIFQLKGGLMSGMGYL
GVETILELKRDSKFVKISSASLRESHTHDVLEN
>BRE_729 adenylyl cyclase, CyaB-type, putative
MFEVELKAFIPKNRVKKIVKLANQKFQFIKEEIKNDIYYFNSKKIIRIRE
SNISKKIITFKIKSLEKDIEINKEIEFKVDKIDNFISFIKELDFKILYKK
IKKSLIYKKDNLNIEVNEIQNLGFFLEIEKIIDNKNELNLAKQEIYKTIQ
DFKLQNNIEKKSYFELLSNQLKK
>BRE_415 adk, adenylate kinase
MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRTNIENDTPLGKEIK
QIVENGQLVPDSITIKVVEDKINTIDNRDNFILDGFPRNINQAIELDRLL
ENIKIINFLINEKLLVKRLSGRRICQSCCKIFNIYTLPTKEKEICDFCQG
ILYQRKDDTKESLKIRLQEYNLQTKPLINFYSNSNRLNNIDASKNINEVQ
KNLMEIISKIEKKLV
>BRE_785 apt, adenine phosphoribosyltransferase
MIFLILMENLMIDKMGYYDRFIMKVPNFPKEGILFYDISNVLLQAEAYKS
LLEDAHALYSSKEIDCIAAIESRGYLIGAPLALKMNLPLLLIRKGGKLPR
QVLREEYELEYGLGSIEIHKDDIKQHTKILLVDDILATGGTIRAAVRLLE
RASGVISDIFCFIELVSIRGRDILGEYNVNSLVRYP
>BRE_624 cdd, cytidine deaminase
MNDNGQDAIIKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNIE
NASFGATRCAEQAAIINMISSVGVQKIDFILVTTIPASVPCAICRQVMSE
FFEEDTKILITDPNQFNMNKKVFKIYTLNDLLKFPFNKEELSKIFKANKT
T
>BRE_131 cmk, cytidylate kinase
MIIAIDGPSASGKSSVSKALSMKLGFKFISSGYLYRIITLIAQRFTLNEY
DLLNESKLVDLISQNDIKYNDNSFLLNGVDVISHILTEKIDFQVSLYSSY
VNIRKIVNKKLREIVKIQDDDYIIEGRDITTVVFPEAKIKIYLDASVEVR
TLRRYNQRDDDMALIELEQALEKRDEIDQNKEYGKLKLGKGVFYIDTSYK
SLDDVCDIIIKTFNLKKK
>BRE_238 dck, deoxyguanosine/deoxyadenosine kinase(I) subunit 2
MDAGLVIVIEGLIGVSKTTLGHILSLDLEIPFYRELNNEFTLSMLNEFYK
DKFRWAFPMQISFLNERFKLIKSVFKSKGKGILDISIYSDCVFASFLNDN
GYISDNEYKIYLDLLDNMLEHSKKPELMIYLDCSIAEAENRIKKRNRSCE
TDISKDYLEKLNKKYLTWYDSYNLSPKLMFNYDKINVFDDREKSNLITFI
KDKLVI
>BRE_1108 guaA, GMP synthase (glutamine-hydrolysing) (glutamine amidotransferase)
MSNNAVVILDFGSQYSQLIARKIREMGVYTIIVTYSLSAKEIKDMNPVGL
ILSGGPASVYLDEAPGVDIEIFDLGIPILGICYGMQLIIKVFEGVISKCD
KQEFGHTELFIDDNKADLFLELPSKFEVMMSHGDNIEKIPEGFKQIAYTK
ICVGAVFNLEKRIYGVQFHPEVSCCDIGNQIFMNFVFKICKAQTNWDLSN
SIEDLVKGIRHEVGDSKVILGLSGGIDSLVCALLINKAIKDNLICVFVDT
GFLRKNEANGILEFNKKYNLNIKHIDSSLLFLTNLRDVDDPEEKRKIIGK
TFVEIFEKVALEEDDIKYLAQGTIYSDVIESDVKNNVCSSTNIKSHHNVG
GLPDKINLNLLEPLRNLFKDEVIQLGVQLGLEEEVLYRHPFPGPGLAIRI
IGEITKDKIDILQGADHIFIEELLINDLYYKVRQAFVVLLPVRTVGVMGD
NRTYEYTAVIRCVNTLDFMTASWVELPYSFLRKVSSRIINEIRGINRVCY
DISSKPPATIEWE
>BRE_422 hpt, hypoxanthine phosphoribosyltransferase
MSDKISTLFTEKKIKSKIKELAQKIRSYYKDKNNVVFISLLKGFFMFFAD
ITREIGLNVKIDFLQASSYGNKTLSSLNVLIKKDIEINIENCYVIIFDDI
VDTGLTYKKIIAHLQTKKPKEIKIFTLFNKPSRRLTEIKIDYTDFEIQND
FIVGYGIDFNEKHRTLRSVAKINQ
>BRE_469 ndk, nucleoside-diphosphate kinase
MHIHELNKLCLIISLHCIKNIGRLFMSTLIQKTLCIVKPDGVRRGLIGNV
VSRFERVGLKIVAAKMVLVDRKMAEEHYLYDDIAARHGESVWKSLVNFLM
SSPVFAFVIEGVESVEVVRKFCGSTEPKMSAPGTIRGDFSYHSFNYANAK
NFAVYNVIHSSASLIDANREIPIWFTKDEIFTYKRDDEFEHYY
>BRE_1046 nrdE, ribonucleoside-diphosphate reductase, alpha subunit
MSYLEHHMMLRILWKGLVMRHLELNNEMMVLRDGFYRLEKDLEALSVFLE
EIKSKSLKFENPNKRMHYLIDNNLYEDFYQKYSEDQILEIYKAVEGEEFK
FKSYMSASKFYKDYALKVKDTYFESYEDRIIAVSLFLADGCFDFALRLAL
DMIKQRYQPATPTFLNAGKYVRGELVSCFLLEVGDSLNSITFNISSAMQL
SKIGGGVALNLSNIRARGEEIRGICNVAKGVIPVMKLLEDGFNYADQMGQ
RKGAGAVYLNIFHYDIEDFLDTKKINADEKSRVQTLSLGVIIPDKFFELA
KQDKNYYALAPYSVYKETGLMMNDIDFDKDYDLLASNPRIIKKEISARDM
LVRIAKLQFESGYPYIMYQTSCNLNHPLKEVGRVKMSNLCTEIFQIQTPS
VIGNYGEGDVIGYDVSCILGSLNIVNVINSDFEFIVDLAMRALTSVVDKS
CINNAPSVRKANDDYRAVGLGVMNLHGFLIKNKIPYESDEALDFVRTFFM
LLNFYSLKSSMNIAKERNSVFKDFKQSEYYNGNYFNMYLNEDFSPRSEVV
REIFSCLQIPSKSDWNNLKGDIQRYGLYHAYRLAVAPTQSISYIQNATTS
LMPIVEPVEARVYGNSTTYYPMPYLSRENAIFFKSAYYMDMRKLIDLVSE
AQRHVDQGISTLLYVTNETSTRELVKLYIYAKNKGLKSLYYTRNKNLSVD
ECILCAI
>BRE_1045 nrdF, ribonucleoside-diphosphate reductase, beta subunit
MRKNREAINWNRLNNGYTKMFWDQNIRQFWVDEEIPISDDKLVWNTLSVD
ERDVYEKVLGGLTLLDTEQGSVGMPRIALAIDNLDYKPILGFMGAMEHMH
AKSYSSIFSSLSNIDRIDYIFDWVKTYRNYQEKLELILGKYNNIHDRMSL
YQALCTSVFLETFLFYSGFFYPLYLAGQGKMVNSGEIINLILRDESVHGV
FVGLLAQEEFDKMTMKEQELAYKEMLLILEKLYSLEREYTKELYSCVGLE
SAVDVFVRYNADKALMNLGFDTKFNIKDTDVNPLVLNGLRTDTKTHDFFS
TKGNGYIKPMRVEPLHDDDFM
>BRE_1047 nrdI, ribonucleoprotein
MVYASKTGNIGRFISKTGLGNIFRIVTGDEIVEEPYVLLTYTIAFGKVPS
EVDKFLEHNFKLMIGVAGSGNKNWGDSFCNAVNLIKDKYGVPEILKFELS
GTSHDVKNFMERISDETLRVK
>BRE_408 nucA, endonuclease precursor
MKKKSKILIILYISILIGFLFLHQNPKIVNKIKEITSNYLEEIKNRFYRP
QIPIKLQEEYLLPQGYLTTQVLHKKYYSLGYAEHARQSEWVAYQLKREMV
ELALILVKEKKITRSKKFFEDPDIKGIAPKLSDYLHSGYDRGHIVSSADM
SFSKEAMRETYFLSNISPQKSSFNSGIWSKLEQKVRKWAISKEKIYIISA
GILTENQGFIGNNKILIPKNFYKIVLSLNNKSNNYEIVAFIIPNKKAKDT
DLKNYVVNVNSIEEKTKIDFFAKLDAKIKKIIKMQKNISSWELK
>BRE_374 pfs-1, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine
MILITSAMDEEAREIHQIIENKEEIKIDNYLGEKKIYKGEIEGHKIISLT
TGIGKVNAAMWNSYIIAKYQITHIINSGTAGGLQESSNIKISDIIISSQT
AFYDFNLTQFDYQIGQVPGFPQKFESDKTLLNKVISIIKDKFQNVNVHIG
LILTGDQFIEDEKQIEKIKNDFKDALAVEMESAAIAQVAYTFNIPFIVTR
SISDFPNNKNNHIDFNKFLQDASKNSAKMVRELIKSI
>BRE_377 pkcI, protein kinase C1 inhibitor
MEEILSDCIFCKIVKNEISCYKVYEDNLILAFLDINPLNIGHTLVIPKQH
SNDILDVNNELDGQLLGVCKKVALSLKKLDFNICQGVNIYSAIGSEAGQV
IFHTHFHVIPRFQGDNLGFKRNCSIELSGDEYLDLSKKISKNI
>BRE_549 prs, phosphoribosyl pyrophosphate synthetase
MSLLMKKSIGIIACPGGRVFAEKIMAELNTIFLDAENKVIEQISQTSNCS
KEDVLKFEGILSSFLEGLEFSNLRFDETMEIPVNFIKFANGEFKSEILKT
IRNKDIFIVQDVSNIYPVTVNNNEEVVMTVNDHLMNLMTTVDACMQAKAN
SVSVIVPSYPYSRQDKKHSREGLTASLFGRFLEELRVKHILTLDIHSKAI
ENVFRKSYFENLNASYEIFDALAELIDIRDSNLVVVSPDTGAVNRNKFFA
SNLKRPLALLYKERDYSKVTHNVTDSNISVTKLLGDVEGKNVFMSDDILA
TGGTFIKAVKLLKSMGAKKIICAVSLPFFNGDAIRYFDKAYEEGYFYKII
GTNAVYHDDKLLSKPWYYEANVAHLFAGAIFAIHNRVSLQRILDRSHDIQ
NLISKS
>BRE_423 purA, adenylosuccinate synthase
MAIYAVVGTQWGDEGKGKIIDFLSSKIDYVVRFNGGNNAGHTIVVNDKKF
IFNLLPSGVLQGAKCILGPSVVIDPLILIQELEVLKNNNIKTEIFISDKA
HIIMPYHIKFDELSEQKKGIHKIGTTKKGIGPCYADKINRIGIRTIDLLN
TEIFANKLKTNLEEKNQIIEKIYNDKPLDYDDILNTYKKYIEILKSLITN
TEKILHHAINSEKYILIEGAQGTMLDIEHGTFPFVTSSNTLITAAAGCGI
PISKIKQKIGIIKAFSSRVGSGPFVTEISNSIGDIIREKGQEYGSTTKRP
RRIGWLDLLTIKKAIALNELNHLALTKLDILNNIESLKICIAYEFQGKIY
DYIPTSCETIEKVKPIYKVFKGFKEDISNIKNYDDLPIEAREYIEFIEKE
VGIQISILSVGSEREKTIFRNQEWSNI
>BRE_424 purB, adenylosuccinate lyase
MEQYLNPLKSRYASKEMLYIFSPKFKYTTWRKLWYNLALVQQELGININN
DQLNELSKQIENIDFKLVAKYEKKFQHEVMAHLYAYADLVGEDAKKILHL
GVTSAYLMDNTDLIQIKEALLLIEKKLTEIIIILKQFSIKYKDLATLAYT
HLQEAQLTTLGKRSSLWLQSLIFDFRELKFILSNMCFRGVKGTVGNQNSF
KELFLSNFDKVKDLDINLAKKMGFEKVYKITGQTYDRKFDSSILNFLSNL
AQSAHKITNDIRFMQHLREIEENFEKHQIGSSAMPYKRNPIYSERVASLA
KFIISLQSSGGLIATTQWLERTLDDSACKRLNIPQAFLATDAILILLNQI
FSNIKVNERIIEKHVQTEMPFILTEDILMKATKNGGDRQILHEKIRTYAM
QVKENLYSGKNENNLIQLILNDKSFKLTSKDINEILNPNKNIGFASSQVE
DFIKEIIDPIIKNQ
>BRE_582 pyrG, CTP synthase
MWAFVLRIEFIWRVLIMDNLKILVITGGVISGIGKGVTSASIARLFKDNL
KITPIKCDGYLNTDPGTINPVEHGEVFVLDDGGEVDMDFGHYERFLNQNS
KSTWNITMGKIYKSILENERRGKYLGRTVQLIPHVTNEIKETILNIAREE
HSELLVIEIGGTVGDMENILFIETMRQIRYDIGIDNIAFVHLTYIPNPAG
INEQKSKPTQQSVKTLNKAGIFPDLIIARSSQLLTRQIRDKIAMFCNVDA
SCIVDNIDVATIYEIPISFYKQGLHKILGSKLKINVTPKVDGLEKLVNVI
KKNLLSPQKVVNIAICGKYTELGDSYASIFESLTHVSANLDILVKTTVID
GINFDEKMMEGVDGIVVPGGFGSRGYEGKIRAIKYARENNIPFLGICLGM
QLAVIEFARNVCGIFDADTEEVLSEDNTMLNSINPVIHLLSEQKELENKG
ATMRLGGYPVLLKKDTLAFKLYGNDMIIERFRHRYEVNNDYLDLFNKYGL
VVSGFSEDFQIVKIIEIPKNKFFVACQFHPELITRLESPSKLFVGLVKAC
L
>BRE_578 smbA, uridylate kinase
MIKIISLGGGIINPNHINTTYIKNLKNLIFQWIKKEHNRKVILITGGGKT
AREYQDAYKQINPKFKNHELDEIGIMATKLNATLISKAMQPFCINDIVSN
PTEDFQFKGQILVASGWKSGFSTDYITVKFAEKFNSNEIINLTNIDQIYD
KDPKKYNDAKGFKNITWNKLQNIVGKDWEPGSHLPFDPIATELALKLGIK
AYILNGTDLTNLQKVFDKNDDFLGTIVVK
>BRE_801 tdk, thymidine kinase
MSYVWGEFVFMGFYLNLVNGDTRSKLDNIVSISHFNFKDNSNLMLIIGPM
GSGKTEYAAKIYKDSLIIKNKSSEILASITRGLRNRANVFFIRNILDKKR
FKNYPENVIPYRGGGSDEIDGVDFASDSFDVGQLIEKNPEYGTFIIDETC
FYDERLVFIVNKIALDLNVLFILPTLLYNFRKEIFNNTARLLIEYADKIC
SLGAYCEHINCMDESFLTYRYYFYEGKEIAAPYFDPLLIVGGDEIVESAI
YPNYATRCFKHHYLVGREYFFTILKPFALLYIQGDRKFLEREIVDLKSNI
VNSNFQKSLLIEVDEKYDITILENVLKLPFLAERALITLSFEYNILSKED
FKEIVNRFSLSKDYIQKVIVSREYKGIF
>BRE_3005 thy1, thymidylate synthase-complementing protein
MNFKIEKENLLNIEHKVLDKGFIKLVDFMGSDERIIQAARISYRGESIKR
EDRELIDYLIRNEHTSPLEQVVFTFYIKAPIFVARQWMRHRTARINEVSS
SYSLIREEFYVPLEENMNTQNVTDNQDNKKTECEFREEILNNLKENQKSS
YKLYQNMINHNISKEISRIVLPLSLYTEWYWQIDLNNLFHFIKLRSALNA
SKEVAEHSSKEMREYAKVLLEIIEKIVPIATKSFKNHILKGCKLSYEEIV
AIADALDISKLKLDANALKRLQDKLNI
>BRE_803 tmk, thymidylate kinase
MTKILKNFYCIEGIDGSGKTSIIQKLQKICNNKMKYHFTKEPSTGIIGKL
IRKQLTNFKNPLRKVSLAHLYVADRYEHLYNIQNGIITILNKNQTKVISD
RYLFSSIAYQGELGYKLNKDFPLPEKLFFIKTDPNIAFKRIQKNRTQADI
FEFEEAKFKEINSRYMEMFQIFNQLIDIVYIENSSEHDLEISARKIFDLI
KF
>BRE_20 udk, uridine kinase
MVKIIGISGGSGSGKTTIVNKISEVISEFVLISQDNYYKSVGDYEYEFLD
VNFDHPDAFDNNLFYKQLKKLKENQSINMPLYDFINHKRRDETIKIVPTP
IIIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLERDMSKRGRTLES
VIEQYLRTTRAGYYRFIEPTKEYADLIIPEGGHNDKALYVLSSFLKTLVK
DSSKFF


# Borrelia turicatae 91E135, 91E135

>BT0544 ribose-phosphate pyrophosphokinase
MGLLIKKSIGIIACPGGRVFADKIMEELKKIFLDSESEVIEKISQTSSCF
KEDVLKLEEILSPFLEGLEFSNLRFDESVEIPVNFVKFANGEFKAEILKT
IRNKDIFIVQDVSNTYPVNVNNNEKVVMTINDHLMNLMTTIDACMQAKAN
SVSVIIPSYPYSRQDKKHSREGLTASLFGRFLEELRVKHILTLDIHSKAI
ENVFRKTYFENLNASYEIFDALAELIDIRDSSLVVVSPDTGAVNRNKFFA
SNLKRPLALLYKERDYSKVTHNVNDSNISVTKLLGDVEGKNVFMSDDILA
TGGTLIKAVKLLKSMGAKKIICAISLPFFNGDAIRYFDKAYEEGYFYKII
GTNAVYHDDRLISKPWYYEANVAHLFAGAIFAIHNRVSLQKILDRSHDIQ
NLISKS
>BT0571 uridylate kinase
MLKIISLGGGIINPDKINIEYIKNLKNLIFKWVQEDNRRKIILITGGGKT
AREYQDAYKQINPKFKNHELDEIGIMATKLNAKLISKAMQPLCIDNIVSD
PTQDFHFKGQIVIASGWKAGFSTDYITVKFAEKFKADEIINLTNVNQIYD
KDPKKFDDAKGLSNITWNELQNIVGKNWEPGSNLPFDPIATKLALKLGIK
AYILNGTDLQNLKKVFDKNDDFLGTIVVK
>BT0791 thymidine kinase
MLFLLILLYLYKKSLTCLEFIFMSFYFNLVSGDTKSKLDDIVSISHFDFK
ANLNLMLIIGPMGSGKTEYAAKIYKDSLIIKNKSSKVLDPITKGRRNRAN
IFFIRNILDKKRFKDYPKNVIPYRGGGSDRIDGVDFAGDSFDVGQLIDDN
PEYGTFIIDETCFYDERLVFILNKIALDSNVLFILPTLLYNFRKEIFNNT
AKLLIEYSDKICRLGAYCEHVNCMDESFLTYRYYFYKGEEIAAPYFDPLL
IVGGDEIVESAIYPNYATRCSRHHYLVGREYFFTILKPFALLYTQGDRKL
FEREIMDLSSNVRNSNFENSLLIESRGKCDIAVLENLLGLPFLAERALIT
LSLECNILSKGDLKELIDKFSLSKDYIQKVIVSKEYQWIF
>BT0015 uridine kinase
MVKIIGITGGSGSGKTTVVNKISEVIPEFVLISQDNYYKSVGDYEYEFLD
VNFDHPDAFDNNLFYKHLKKLKENKLIHMPLYDFINHKRKDETVEIVPTP
VVIVEGIMIFVEERVRNLIDLKIYIDTPNDIRFIRRLERDMSKRGRTLES
VIEQYLSTTRAGYYRFIEPTKEYADLIIPEGGHNDKALYVLSSFLRTLGQ
ESSVFF
>BT0379 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
METILSGCIFCKIVKNEMSCYKVYENELVLAFLDINPLNVGHTLVIPKQH
SNDALGMSDELNGQILKVCKKVALSLKKLGSNICNGINIYSAIGSDAGQV
IFHTHFHVVPRFKGDNFGFTRGSNIELSGDEFLDLSKHISQNI
>BT0777 adenine phosphoribosyltransferase
MWEILMKDKTEYYDKFIMKVPNFPKEGILFYDITNVLLKAEAYKSLIEDA
HAFYLSRNIDYIAAIESRGYLIGAPLALKMGLPLLLIRKEGKLPRQVLRE
EYNLEYGFSSIEIHKDDVKQHSNILLVDDILATGGTLKAAAMLLKKSGGV
VSDIFCFIELVSMNGKDALREYSLNSLVKYF
>BT0417 adenylate kinase
MKLVFLGPPGSGKGTIAKILSGKLNYYHISTGDLFRANISNATPLGKEIK
QIVENGQLVPDSITIKIVEDKINTLANKDNFILDGFPRNINQAKALDTFL
QNIQIINFLLDEAILIKRLSGRRICQSCGGIFNIYTLPTKEKGICDLCKG
SLYQRKDDVEESLKIRLQEYHLQTKPLIDFYSKNNRLNNINASKDIDGVE
KSLIEIISKY
>BT0618 cytidine deaminase
MKDNEQNAIVKAFQLAETARNNAYSPYSKFKVGACIKTKDNLFFQGSNVE
NASFGATRCAEQAAIMNMISSVGIQKIDFMLITTTPASVPCAICRQVMSE
FFEENTKILMTDPNQFNATKTISQTYTLKDLLKIPFNKEELSRIFKANQE
T
>BT0421A hypoxanthine-guanine phosphoribosyltransferase
MSDKISTLFTEEKIKSKIKDLAQKIRNYYEDKNNVVFISLLKGSFIFFAD
ITREIGLNVKIDFLQASSYKNKTLSSLNVLIKKDIDINIQNSYVIIFDDI
IDTGLTYKKIVEHLKTKNPKEIKICTLFNKPSRRLIELKIDYSGFEIEND
FIVGYGIDFNEQHRTLKNVAKISK
>BT0128 cytidylate kinase
MVIAIDGPSASGKSSIAKALGMRLGFKFISSGYFYRIITLIAQRFSLNEY
DLLSESKILELVSQNDIKFNGFDFLLNGTNVISHILNERIDFQVSLYSSY
IGVRNIVNKKLREIVKLKDDNYIIEGRDITTVVFPEAEVKIYLDASVKVR
ALRRYNQRSDNVTLNELEQALERRDEIDQNKEYGKLKLDKEVFYIDTSYK
CLDDVCNIIIKTFNLKKKVIER
>BT0411 endonuclease
MNKRLKILFCFYILILLGFLFLYQNPKILNNIKEIAYNYLSKLKDKIYEP
EISTELKEEYLLPKGYLTTQIIHKKYYSLGYAESARQSEWVAYQLKREMV
ELALTLLREKKITRSKNFFEDQDIKGIAPKLSDYLKSGYDRGHIVSSADM
SFSKDAMLDTYFLSNISPQQREFNSGIWLKLEQLVRKWAILKEKIYIVSA
GILTENKGFIGKNKILVPKNFYKIVLSLNNNNFYDILAFIIPNEKAQDLE
LRNYVVNVNLIEEKTKINFFAKLDAEIKKIIKMKKDVRSWKFR
>BT0375 5'-methylthioadenosine nucleosidase
MILITSAMDEESIEINKIIENKEEIILDDYSGEKKIYKGEIAGHKVISLT
TGIGKVNAAMWNSYIISKYKITHIINSGTAGGLKESEDLKITDIIVSSET
AFHDFNLTKFGHKIGQVPGFPQKFKADENLLNKVVNIIEDKLKNISVHIG
LILTGDQFIGDKKQLEEIKNNFADALAVEMESAAIAQVAHTFKIPFIITR
SVSDLPNIKDNHIDFNKFLQDASMNSAKIVKELIKLI
>BT0575 CTP synthase
MIDNLKILVVTGGVISGIGKGVTSASIARLFKDNLKITPIKCDGYLNTDP
GTINPVEHGEVFVLDDGGEVDMDFGHYERFLNLNSKSNWNITMGKIYKNI
LENERHGKYLGRTVQLIPHVTDEIRETIFKIAKEESSELLVIEIGGTVGD
MENILFIETMRQIRYEIGSDNIAFVHLTYIPSPVGINEQKSKPTQQSVKT
LNKAGIFPDLIIARSSQLLTKQMRQKIAMFCNVDTLSIIDNTDVSTIYEI
PISFYKQGLHEILGSKLKINVKPKVDGLERLVGIIKRNLVSPQRIVNIAI
CGKYTELGDSYASIFESLTHVSANLDILVKTTVIDSTNFDERMLKGIDGI
VVPGGFGGRGYAGKIRAIKYARENDIPFLGICLGMQLAVIEFARNVCGIF
DADTEEILSEGNSICSSITPVIHLLPEQKEFTDKGATMRLGGYSVLLKKD
TLAFKLYGSEMIVERFRHRYEVNNDYLDSFNNHGLIVSGFSEDFRIVKIM
EIPKNKFFVGCQFHPELITRLENPSKLFVGLVKACL
>BT0421C adenylosuccinate lyase
MDKYINPLKSRYASKEMLYIFSPKFKYTTWRKLWYNLALVQKELGINISN
KQLNKLSKHIENIDFELVKKYESKFQHEVMAHLYAYADLAGDDARKILHL
GVTSAYLMDNTDLVQIKEALLLIENKLLKLINTLKKFSIKHKNLVTLAYT
HLQEAQLTTLGKRSSLWLQSLIFDFEELKFIMSNMRFRGVKGTVGNQSSF
KELFASNFEKVKDLDINLAKKMGFDKVYQITSQTYDRKFDSSILNFLSNL
AQSAHKITNDIRFMQHLKEIEEHFEPHQIGSSAMPYKRNPIYSERIASLA
KFIMSLQSSGGFIAATQWLERTLDDSACKRLNIPQAFLAADATLILLSKV
FNNIRVNKKMIEKHVKTEMPFILTEDILMKATKNGGDRQILHEKIRIYSM
KVKENIYSGTTENDLIKLILNDQSFKLTSKDIDEILNPNENIGFASYQVE
NFITEIIDPILEKNKEN
>BT0247 nucleoside-triphosphatase
MKTLFFATTNINKINEVKQILDIPNIKIKIPKNFDVKETGKTFKENSLLK
AKTLFESLDKKKPVFSEDSGLCIKALNLEPGIYSKRYDQYKLGKKLGTNE
KNHLIIDLMKDKENRTAYFICIVSHISIDGTITNFEGILNGTIALDIDCY
KKNGFGYDPIFLTANNKRLSELTLTEKNKISHRGIAFAKFKKFLMQSLN
>BT0463 nucleoside diphosphate kinase
MSTLIQRTLCIIKPDGVRRGLIGNVISRFERTGLKIVAAKMILVNREMAE
THYLYDDIAVRHGEFVWQSLINFIISSPVFVFVVEGVEAVEVVRKFCGST
EPKMASPGTIRGDFAYHSFNYANEKEFSVYNVIHASANVDDALREVSLWF
KENEILTYKRDDEFEHYYG
>BT0723 adenylate cyclase
MFEIELKAFIPKNKLKEILKLANQKFKFIKEEIKDDTYYCNTEKIIRIRK
FNTLEKIVTFKIKSLENDIEINKEIEFKVDQVNNFISFLEEMNFKFLYKK
IKKSLIYKKENLNIEINEIENLGFFLEIEKIIYDKNELSFAKTEIYKTIK
EFKLQNNIEKKSYFELILANQSKV
>BT0239 deoxyguanosine kinase
MEAGLVIVIEGLIGVGKTTLGHVLSKEFNIPFYSELNNEFTLSMLDKFYK
DKSRWAFLVQINFLNERFKLIKSIFKTKGGILDRSIYGDRVFASLLNDSG
YISNDEYKIYLDLLDNMLEHSQKPVLMIYLDCSVDEAERRIKNRNRSFET
GIPREYLEGLNEKYLSWYDSYDLSPKLSFDYNSINIFDDKHKSKLIAFIK
DKLVI
>BT0819 cytidylate kinase
MRIAVSSKSGCGNTTISGMLAKHYGLKLINYTFHDIAREKNMSFDTFYEK
EIIGRNDHYWDEYLDSKLLELSKEDNTVLASRLAIWLAKNADLKIYLYAK
IEIRAERIINREGGMYSDILRSTFNRDSNDSKRYLSVYNIDIDNYLDVAD
FIVDTTDKSANKVFELIKDEIEKRGLYIK
>BT0421B adenylosuccinate synthetase
MSIYAVIGTQWGDEGKGKIIDFLSSKIDYVVRFNGGNNAGHTIVVNNKKF
IFNLLPSGVLQGAKCILGPGVVIDPLILIKELEALKHNNIKTEIFISDKA
HIIMPYHIKLDELNEQKKGVYKIGTTKRGIGPCYADKINRTGIRAVDLLD
IKIFERKLKINLDEKNEIIEKIYNHKPFNYDDILSKYKKCIAILQYAITN
TEEILNQAINSGKIILIEGAQGTMLDIEHGTFPFVTSSNTLITATTGCGI
PISKIKEKIGIVKAFSSRVGSGPFVTEILGPIGDKIREKGQEYGSTTNRP
RRIGWLDLLTIKKSISLNELNHLALTKLDILNNIEDLKICTAYEFKGKIY
DYIPTSCEILENVKPVYKVFKGFKQNIRNISHYEDLPIEAKEYIEFIERE
VGVQISILSLGAEREKTIFRNQKWINI
>BT0793 thymidylate kinase
MNKILKNFYCIEGIDGSGKTSIIQKLQKLCNNKLKYYFTKEPSQGVIGEF
IRQQLTNFKNPLRKVSLAYLYVADRYEHLYNTKNGIIEILNKGKTKVITD
RYLFSSIAYQGELGYKLNKDFPLPEKLFFIKTDPGIAYKRIQENRIQADL
FEFEAAKFKEINSRYTEMLKIFDDLIDIVYIENSNEEDLETSTRKIFDLI
KF


# Leptospira biflexa serovar Patoc strain Patoc 1 (Ames), Patoc 1 (Ames)

>LBF_1881 Adenylosuccinate synthase
MPANLVVGAQWGDEGKAKVIDYLSKDTDIIVRYQGGANAGHTVVVGGKKY
IFHLVPSGIIYDNTTCVIGNGVVLDPEYFLKECADLETHGFRVKDKVLIS
DSCHILLPYHRLIDEAREAGSSPERKIGTTKKGIGMCYADKMLRNGVRAG
DLLDKENLKRKLNHILEVKNQELVKYYDLEPVNPNEMYDFLLDFADKMGK
NIINTVYYLNSELEKGKRVLLEGAQGTGLDIDFGTYPYVTSSNPTTGGAL
AGSGVSFRYLKDVIGITKAYATRVGEGPFPSEILGEAGDVLRKLGGEYGS
TTGRPRRCGWFDVQMIKHAVTVNGINSLVLTKIDVLSHYETIPVVVGYEY
KGKKLDFFPSQGLEDVKPLFAEYKGWKDDISGINSFAKLPPLCQSYIKSL
QELVNTKIGIVSTGPDRDHTIIMD
>LBF_1441 HIT family hydrolase
MEDCIFCKIIRGEIPAKKEYETDSIFVFHDITPQAPIHLLIIPKAHIKSM
NEIDSLDPKVIHQIFEVIPELAKKNGIFEKGYRVVNNCGTYGGQTVGHLH
FHLLGGRHLQWPPG
>LBF_0299 Cyclic amidohydrolase
METIAGKIVTHEKEFLGSIEFDPTTGLITKVKEGIEPKSRQFSEDCVIFP
GFGDIHIHAREDVTGKHTYKEDFLSASAAAINGGVIHVADMPNNPVPPID
DATYAAKQALTEKAPIHITLYAGIGPHTKPLSKKVPYKVFMGPSIGELFF
HDNPSLEEVIQHYEGQDVSFHCEDPEILIANKDQPTHETRRPKEAETVAT
DFALYLIEKYNLKGKLCHYSTKDGLSKIIAAKKRGVKVTCEVTPTHLMFD
TDMLTETNHKWFQMNPPLRGRADREAMVKGILDGHIDYLATDHAPHSIEE
KQKGTSGISQLDTYGLFVTYMILNLNIPMTLIAKICSKNPGEFVAPYLPK
QFGKGVGVINEGYAANFSILNLKKPVEFKKSMIKSKSGWSPFEGFQFPGS
IEAVYYLGKEIHAK
>LBF_3186 Thymidylate synthase-complementing protein
MQQSDFESISRVSVPELDSILGKPFPILDDGFVRLVDYMGSDESIVQAAR
VSYGKGTKKVNEDRGLIRYLMRHRHSTPFEMCELKLHVRVPMDTWRQWIR
HRMANVNEYSTRYSVAIDSAQTTLPGEWRVQSVGNKQGSDGYLESSKGDH
LTKRETEFQKFANDIYNERLEMGVAREQARKDLPLATYTEAYWKIDLHNL
LHFLALRMDDHAQLEIRLFAKTIGEQIVQKWVPHTWEAFVDYRLSALHLT
KYDTEIIAALNVSGKEGAIKKAIQLGMLDDQGTTAKKSREREELEYKLSQ
LGFSIPW
>LBF_4124 Phosphoribosyltransferase
MSIVKSKIRTIPDYPKPGILFRDITSLLIDPEGFQLTIGMFVERYQNAKL
NKIAAIDARGFIPGAALAFQLGVGFVPIRKKGKLPGNTISESYALEYGVD
HVEIHTDAIVPGDKVLIMDDLIATGGTLEASIKLIQNLKGQIHECSTIIN
LPDLGGAKRIKDTYGIDVFSICEFEGH
>LBF_1110 Metal-dependent hydrolase
MTRPILLQSASMYQNGKMETKDIVFTGETITKIEDSIPSNNVMFSISLKG
KKLYPGFINSHDHLLASYLPKVGGTEKHLSWLSYDNLYKSSGVFAERQQI
DPEILYYLGAYKNLFAGVTSVFDHIPHFVQNPFRGILPVKLISDYTLAHS
VGNYSLDWGEGPALEYRMAEHANLPFVTHLAEGLDDDSKQSLRYLEKMDA
LGAHSVLVHCLPFGPKEADKIAEKGASVVWCPTSNLHIFGKTTNIKLFLE
RGVNVCLGTESSPSGSNHFLEEIKTAKSIYFGLYGEELSDSDLFKMITEN
PRKAFRMGNPNALMPGLKCDFVVVNDEKKSTELNVSDLHWKHIDLVVIDG
YPIYGSSEFLSLFQEFGLSTEEFVIDGKNKLVAGSPKKLMKQVSESVGYK
KSLAFLPNF
>LBF_1868 Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase domain
MKVRVVTFPGSNCDKDVGSVLQESFQAEVIYTWYKESFEDVPDLVVLPGG
FSFGDYLRCGAMAKFSPSMESVVKYANKGGKVLGVCNGFQILTESGLLPG
ALLHNRTLKYICKDVELVPVKENSFAKKMEGTLSIPIAHGEGAYFADPET
LERLEKNGQVVFRYRENPNGSLHDIAGICNERGNVLGMMPHPERAMNPYT
GKMDGKQILEALLKN
>LBF_0151 Adenosine deaminase
MYIDLHNHLYGCLPPETLFRIGKKNPNPRWHLYLDSYEKAYGTKIRPSTF
FDDYADKNEFAKLYHFLEKAPFLHFQAKFNLIIALVKFDEPEITEVSHDV
VFSNSLEDISYAEYRLMFGKEEPKESFYSKLMASLEGLKKGEESAKKAGK
PIQGKLVMSLHRDLNFERHYDWMKNWMEKESVIRDGLVGIDFCHIEEGHP
PKDKRLFFQSIQKDNKAEPNTALSILYHVGESFRDKTPFSAVRWILESAE
YGAHRLGHALALGIDSDYFLGEERTEFVSEAKDQVEHELMYFDEITTYGP
FYAKEELEIKRKEYKTKPDTEILTIPFDETQSQYLHTFQNYAMSKIAKSN
AVIECCPSSNLYIGMLESHIDHPITRFLQNDLKLTIGSDDPGLFGTTMAE
EYHHAHTAGVSDKDLEILRSVSLDYRSTKLSGRELD
>LBF_3344 Cytosine/adenosine deaminase
MDFYESFLKRYSIEVSKYKNEIPSYSEIITKDGNLVSSSFNSVEQTLNPT
KHSEILAIEKALSHVDGRYLSEHILITALEPCILCAGAVVRVKLPEVVYF
LPAKPGEGISSYTTESIYLLNHFPKCTLIPESRIKFEFLSFFKEKR
>LBF_0071 Purine-nucleoside phosphorylase
MANVVKIGVIGGTGLYSIDGMEILKEIHPDTPWGKPSDTITIGRFKGKEI
AFLPRHGKGHFLNPSEVPARANIAALKQLGVEEIIAFSSVGSLRQEIAPR
DFVIPSQIIDRTKSRHATFFENGMVAHAPFADPFSSGLAKKVEEAAKQIN
LPIHTNKTLICMEGPLFSTRAESHMYRSWGADIINMTVLPEAKLAREAEI
LYQMVCMSTDYDCWKEDEAHVTLEMVLANLSTNADTAKKLLSTLIDLLGK
SDDTSLVGSTKFSLVTAPEKRNPEQINKLKFLFPSYF
>LBF_1462 HIT family hydrolase
MTCPICQAHKNPSEILFENEFWILRKANQNLDGYLYLEIKGHIESWNQLT
MEQFEAYGRALHKGTELIESSHPEKIYMTAIAERVPHLHVHLIPRFKGQT
PGIEHIAQATGPGFPKPM
>LBF_2585 Xanthosine triphosphate pyrophosphatase
MTKKTLAFASGSDHKTKEMQMLLSPFGYEIVTPKILGIPFSPEETESTFV
GNSFIKSKELFRLTGFPSFADDSGISVDALGGEPGVLSARFGGPGLSDKD
RALYLLNKLGTNHNRKAHYSCVVSFVDANHQVSFEGKVEGLIASDYDELG
KFGFGYDPIFYYPEFGKRFSEVPEGEKNKVSHRKKAMELFLEWFQTIQ
>LBF_1710 HIT family hydrolase
MSSYEEHSIRKNLFSIGKLGYAKGDRPNVECILCGVRDKNEIVPNLTIAE
TDLSIVSINLFPYNPGHIIIFPKRHIIHYLELTDEEALDIHRLTQKTMRI
LEQQWKVQGFNTGYNLGKNSGGSIPHIHEHIVPRFPNEAGFLDVLSNTRI
VIYEPYQMWEDLKKLWVKEEN
>LBF_0040 add, Adenosine deaminase
MEVPFSEILSRISVIDRDIAELNRLKSRLPADRPYSPTIQLTFDKQINTL
LNERVSLMELPILHPPLWLLPKEGAEGLEQTTLLKERKSLLAGDLSVAHP
NEQDVINFIREIPKTEVHLHLEACVNKETLKFLYKKNGIEVTDQEFEDKY
NFKDLNGFIQVFFFVQGSVKEASDLGYFIDSLADYLRSNHIVYCEAFFAP
SKFIQNGLDFDEMVEVMVNRIRQIEVKDGISIRLLVDVSRSFGPENAMNN
LKRVLGLKQKEVIGIGLGGAELMGPAKDYAEVFKIARESGLRCVAHSGED
DGPWAIWDAVNLCKAERIGHGTSAIQDPELVRYMKENKIPIEICVTSNVF
TGKYVRKEQNHPVRYYYDQGLMLCINTDDPDIFNVNLTYEYFKLYRFLDF
SIDELIDLVRQGVLCTFHPEKETLWKSMEEKIDLIKLKYNLNSEKQVLSV
>LBF_1892 adk, Adenylate kinase
MKRLIFMGPPGAGKGTQADIIKEKYNIPQISTGDILRAAVKNGTAMGIEA
KKYMDAGDLVPDAVVIGIIRDRLVEADCANGFILDGFPRTVEQAKALSEI
LKELHMELDSVVNLDVPDEELVKRLLGRAIKEGRSDDNEETIKNRLHTYN
TKTLPLIDFYKATGILRQINGLGSMEEITNTILKSI
>LBF_0786 carA, Carbamoyl-phosphate synthase (glutamine- hydrolyzing), small subunit
MQAFLVLANGTVMKGRSFGANKNSIGEVVFNTSMAGYQEILTDPSYKGQL
VTLTYPMIGNYGINPDDMESDRIQASGLIVKEYVKRPSNFQSKETLSEFL
IRFGVPAIEGIDTRKLTRIIRNSGAMNCGIFISETYEDSFLETVKNAPSM
EGQDLAQIVTCEKPYVFGAHSPSKFKLAVYDFGIKRNILRLLDSAGFNVH
VFPAKTKAEDLLKEGFDAFFLSNGPGDPAPLDYAIQSAKTIMDAKKPLFG
ICLGHQIIGLALGKKTAKLKFGHRGGNHPVRNEETGKIEITSQNHGFHVL
GESSEDMPITRLNLFDNTVAGLKTKGLPVMAVQYHPEACPGPHDSAYHFQ
EFYTMVETSKG
>LBF_1227 carB, Carbamoyl-phosphate synthase (glutamine- hydrolyzing), large subunit
MPQRNDLKSILIIGSGPIVIGQACEFDYSGTQATKALREKGIRVILVNSN
PATIMTDPDLADATYIEPLTVPVLEKIIKKEKPDAILPTVGGQTALNLAL
ALHREGVLEKYNVELIGAKVDAIRKAEDRELFKLAMEKLGIRVAKSFMVS
DMEAARKAKDEIGFPIIIRPAFTLGGTGGGTCYEESEFEEIAQKGLSASP
ISQILVEESVMGWKEFELEVMRDLNDNVVIICSIENLDPMGVHTGDSITV
APQQTLSDKEYQRLRDMSIDIIREIGVETGGSNIQFAVNPENGDVIVIEM
NPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIRNDITRVTPASFEPS
IDYVVTKIPRFAFEKFPGSDNTLGVQMKAVGEAMAIGRNFKESFQKALRS
LETDRFGFGSDGYLKELMEWETVPKEQRHEWLTARVKRPTDKRIFYVKMA
FDFGMSVEEIHEICKIDPWFLYQFEELFQLENKYRKDGNTIIEEMKQAGF
SNRQLAFLSKEEQILAQVRSGAAIEITKAKVEKTLREEEEKIESYLEEKN
IHPVYKRIDTCAGEFEAFTPYMYSTYDEEDESDVTSKKKVMILGGGPNRI
GQGIEFDYCCCHASFSLQEAGVESIMVNSNPETVSTDYDTSDRLYFEPLS
LEDVMAIFKKERPDGVIVQLGGQTPLKLAKSLEKRGVPILGTSPDSIDRA
EDRKRFAEVLEKLNLKSPENGIASSKDKAREIARKIGYPVLVRPSYVLGG
RAMLIVNEETELDKYMEEAEEVSEDRPLLVDSFLQDATEVDVDALCDGKD
VFIAGVMEHIEEAGIHSGDSACVLPPQSISQRMIQEIEEATLRLALELDV
KGLINVQYAIKDETLYVLEVNPRASRTVPFVAKSIGIPIVKIAVRLMLGE
SLASFKLGKRFSAPMITVKEAVLPFSKFPGVDTILGPEMRSTGEVMGVAA
TKGEAFVKAQIMAGEEPPKHGTVFVTINDKTKKELLESVRSLSNLGYNII
ATEGTHKFLSDNGILSSKINKIYDGYFPNVIDYIKEKKIHLIINTPLSRV
TRENAFTIRQAAIKYKVPCLTTAQAAKALIHGLVEMKDKGFSVNSLQEIH
KKK
>LBF_2516 cmk, Cytidylate kinase
MSLQSIENVIAIDGPAGSGKSTLARMIAHKLGFHYLDSGAFYRALTFALL
EKFKETKEDESKFPFYTEKLADATLLEKDESEFGFSVAAIPVHCELSSTG
ENLMFLGERDISREIRDPEITKKIRYIAPRRAFREILNRHIREFAKTHRL
VMDGRDIGTEVFPKSKFKFFLTASVEVRAKRRYDELVTKGFKADLNHIKE
EIVARDESDTTRTVAPLKQASDAILIDTSTLDTETVLNTILSKVSPSGQI
>LBF_3134 dcd, dCTP deaminase
MILTGKEILKRLGSDIKIEPYDEKLLNPNSYNLRLHEDLLVYSEFPLDMK
KPNPVRTLKIPEEGLLLEPGNLYLGRTIEFTETHNLVPMLEGRSSIGRLG
MFVHITAGFGDVGFKGFWTLEIQVTHPLRVYSGVQICQIFYHTVEGEISE
YKSGKYQANQGIQPSLLYKDFEKK
>LBF_1427 dgt, Deoxyguanosinetriphosphate triphosphohydrolase
MKKGRNELLNDEEKILATYAVGSRNFGGRAYEEPEHPYRLPFQRDKDRII
HSHAFKRLEYKTQVFVYSEGDHFRNRLTHTLEVAGISKTISKVLGLNEDL
SESIALAHDLGHSPFGHAGQEALAELMKDIGGFEHNKQSLRVVQKLERRY
PNFPGLNLCEETLLGIMKHGGGYESSNLLEVRRTLGPSLEAMIVDASDEI
TYSAHDLEDGLESGLLQLEEVKGLMIWKRIDESLPSSEKNSKTEMLSISR
SIGRISLNLMVSDLIESIHKILTEYSVNSRESISKLYQKKIKIVQFSEEF
QKEFNELKQFLFQNLYRHSEVSRMSERGKETIYLLFKHFESHPESIPESY
RNREEEDGRMRVICDYIAGMTDRYAIEKLKREGILWFPY
>LBF_1478 dut, dUTP diphosphatase
MLEPENYLQIQILKEGAVLPEYKTPGAAGMDLSACLSENLLLPKGEVVLV
PTGLAMAIPEGYEGQIRPRSGFSTKHRIIMPNSPGTIDSDYRGEILIPLL
NLSGEDFVLKPGTRVAQLVIQAVSQLPIQVVTGLDATQRGTGGFGSTGK
>LBF_0917 gmk, Guanylate kinase
MKAVPNLYIISSVAGGGKSTIIQALLKENPEFYFSISCTTRDPRPGDEEG
KTYYFLTIPEFQKKIADGEFYEWAEVHGNYYGTPKAPILDAIKEHRVALM
DLDVQGAKSVKQLRPESVTIFIEPPSREIWIERLIRRGTDSKTSIEKRIE
NGIIELDEAPSFDYVVINDRLEDAITEVKAILCGTKS
>LBF_0428 gppA, Guanosine-5'-triphosphate, 3'-diphosphatepyrophosphatase
MLPFSQILRKPNQAFRSEKILAAIDLGTNSFHIVVVKLRPDGTLEYLTKE
KESVRLGSGSSDYAVIKDDAIERGIACLKRFKTLADSYKAEIRAVATSAL
REAENRQVFLDRAEKETSIQIQVISGNEEARLIYLGILQGLPVFDKRILL
IDIGGGSTELLIGEKGEILFSTSMKLGAIRLTEKYLKKDPLSATDLQKCR
IHIESVLSAFLPQIERLKPFLVVGSSGTITSVTSMVLEKKGEKRERLNGT
EITIDLFKEIRKQVLDAESIKKRLKIPGLDAKRGDIIVGGVLVLDEVLQR
IKAPSFTVSDFALREGIVYDTIESWYRHTDTSLPRLDNIRDKAIKTVANL
YPQGKKHAEAVTKLTLQLFDDLTNLHGLGNLERDYLETACYLHQVGLCIS
HHNYHKHSYYIIRNSEAMVGFSNAEIEIIALLARYHRKGGPKGKHEEFKN
LRPEDQLLVKKLASFLRIGDGLDRSEKSIIDRLDAVVEKGKVSCRLYFKK
NEDPNLEIWSVSEKKDLFEDTFSTTLEFHLHPI
>LBF_2760 guaA-1, Glutamine amidotransferase
MRAVIIRFIDCEGPGILEPILREKGYRISYQNAFDSRVQLMPEIHLNFDL
IIMLGGPQSVADPDEQEFFKPYYEIVENVAVLPNKKLIGICLGSQIIARA
LGANVRPGTKGPETGFSDLQILKPEHPIFSGLNGDSLLAFHLHEDIFDIP
VGAEHLLASEFYANQMFSYKNKIFAFQTHLEPTLEMLHVWQNVHKEFIAK
GTGDFSNLKSKQKTMEESAKILFRNIINL
>LBF_1564 guaA-2, GMP synthase (glutamine-hydrolyzing)
MTSDKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPLSRYESYAGII
LSGGPSSVYETGAPLLPAGFFDTSVPVLGICYGHQLMMKTLGGEVVSAST
KEYGPAILEIENPNSPLSQSLSLKTKVWMSHGDEVVRLPNDFQVIAKSDH
CRYAFVSHPSKNLFGIQFHPEVTHSEEGEILLKNFVELCGASGTWSIQHF
LDEQIQSLQKKVPEGKNVFLLVSGGVDSSVAYLLLAKALGKDRVKGLLVD
TGFMRKNEVKDLMDNLHHVGFDLTIWDESEVFYKSLQNEFEPEKKRRIVG
DLFLEAQGKATTSLGLDAEHWLLGQGTIYPDTIESGGTKHSHKIKTHHNR
VPQIEALIREGKIVEPIADLYKDEVRELGRTLGLPERWIERHPFPGPGLV
VRMIASPRTSPPNIDFSIWKEKIPKAEIQILPILSVGVQGDQRSYAHCAV
LSDFTSDWKELDNLSVEITNTKKEINRVVLAPGITHFEKDFFYTKLTLDK
THADILRDADAIVNQILYDESIHNQIWQMPVVLVPVGLRENSYGVVLRPV
ESTEAMTANFYQMNRNILARITKELLELPQISLVMYDLTHKPPGTIEWE
>LBF_3048 hpt, Hypoxanthine phosphoribosyltransferase
MKPLYSEERIHQRVEELAREISRDFLSKDLVVIGILNGGFIFTADLCRSI
AIPHEVDFMGASSYGDGTSSGDFKITKELKKSIQNKSVLLVEDIVDTGKT
LEYLLLEVQKQNPKDLKVAALFWKQKKANPHIIVDYPGFIIEDDFLVGYG
LDFQGKYRNLPYVAKLEGTD
>LBF_1218 imdH, Inosine-5'-monophosphate dehydrogenase
MSNHPLPGTELLDGVSGQELFSVNMGLTYRDFLVLPGYIDFNPSDVELET
KLSKNISLKRPLMSSPMDTVTESEMAIAQALMGGIGIIHYNNTIEEQVDL
VRKVKRFENGFIKDPILLSPEHTVADLDAVKEKYGFSGIPITENGTANSK
LVGIVTNRDVDFEKDRNIKLGKVMTTELITANVGISLLEANDILRTSKKG
KLPIVDKQGKLVALICRSDLKKNKEFPQSSKDDQKRLRVGAALSTLPESR
DRMAALAGVGVDAIIIDSAQGNSSYQIEMIQWIKSNFPNIDVIGGNVVTK
AQAANLIGAGADGLRIGMGPGSICITQDTMAVGRAQATAVFKTAEYAQAH
GVPVIADGGISNIGDIANALAIGASMCMMGSMFAGTKEAPGEYFYENGIR
LKKYRGMASLEAMSKGGDKRYFSESQKIKVAQGVSGYVVDKGSVLNLIPY
LVQGLRQSFQDMGYRNIPDLHKALREGKLRFERRTESAQAQGSVHGLYSY
TKPSMRAE
>LBF_0084 ndk, Nucleoside-diphosphate kinase
MERTFIMLKPDAVKNKHIGDILQRIEKEGFKILGMKFLKLSLEDAKQFYA
VHAARPFYNDLCTYMASGPIVACALERDNAVAHWRDVIGATDPKEAKAGT
IRALFAESKEANAVHGSDSVANALQEIAFFFKGYELN
>LBF_1636 nrdA, Ribonucleoside-triphosphate reductase, alpha subunit
MKIERHFTKGNKGLYPNLTWVRKDSKITNTDGSVVFEANGVEVPDFWSQV
ATDILAQKYFRRKGVPKYLKKVSEKGIPEWLQRSVPDDEKLAALNPEDRY
VGELDSKQVFHRLAGCWTYWGYKYGYFTEEDSARVFYEEVIFMLASQMAA
PNSPQWFNTGLHWAYGIDGKSQGHYYVDPKSGKLVRSASSYEHPQPHACF
IQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRAANESLSGGGK
SSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDMDHPDIEEFIDWKVQE
EKKVASLVTGSILNNRLLNDIMSACASAKQSLGEEKAYDPAANVELKKAI
QKARKAFVPDNYIKRVIDLSKQGYKDLLFEELTTDWQSEAYNTVSGQNSN
NSVRITNEFMEAVEKDLPFHLINRTEKENARKDGREPKAAKTLRARDLWE
RIANAAWNSADPGTQYHSTINEWHTCPEDGAINASNPCSEYMFLDNTACN
LASANLVKFLKEDGTFDVEGYRYLNKIWTIILEISVLMAQFPSKEIAELS
YKFRTLGLGYANLGSLLMIMGIPYDSQEAMAVTGAISSIMHMTAYATSAE
MAKELGPFAGYEKNKNHMLRVIRNHRRAAYNAPKEEYEGLTITPVGINPS
FLPSYLLEAAKEDSDRALELGEQYGYRNAQVTVIAPTGTIGLVMDCDTTG
IEPDFALVKYKKLAGGGYFKIINQSVPAALKKLGYSQAEQDAIVNYCKGH
ATFNGAPGVNTARLKEKGFTEDVLEKLEKQLPFVFDIQFAFNKFTLGEDF
LAKTLGIDPSLYNSMGFNLLETLGFSADEITQANDYVCGTMTIENAPFIK
EKDLPVFDCANKCGKYGKRFLSYQSHIRIMAAAQPFISGAISKTINLPEE
ATIEDVKNAYLMSWKVMIKANALYRDGSKLSQPLNSVFQLLSAVGEDEEE
LQTSSAPKTVTEVAEKLVYKYISERRKLPHRRAGYTQKAMVGGHKVYLRT
GEYEDGQLGEIFIDMHKEGAAFRSLMNAFAIAVSLGLQHGVPLEEFVEAF
TFFKFEPNGMVSGNPHIKMSTSVIDYIFRELAITYLGRYDLAQVSPDDLR
TDEVGRKAEPAKDNVGKLESSGPRTPLPVNAISMKSVLEDKQEVVVAVAG
QSTQPTQAQSAAATLKIIAEARTKGYTGDSCTECGSFQMVRNGACLKCIS
CGSTTGCS
>LBF_0229 prsA, Ribose-phosphate diphosphokinase
MNPSEVVVFSGNANRPLAEEICKNLKIPNGQISVKRFSDGESSVKIEENV
RGRDVFVVQSISYPANDSLMELLLIIDAARRASARRITAVIPYYGYGRQD
RKVEPRVPISARMVADLIETVGPDRVLTMDLHADQIQGFFRIPVDHLYFS
PVLAEYINSLGMDDLVIVSPDSGGAERARNFGKKVNGSLAIIDKRRPKAN
ESVVMHVIGDIKDKNCLLLDDMIDTGGTIAKAATALYENGAKSVLCCASH
GVLSGEAPSKLNEAKFNPIVLSNSIVIPESKKINHLKTLSIAPLFAKAIE
RIHNEESISSLFS
>LBF_0049 purB, Adenylosuccinate lyase
MIDRYSHPEISAIWELENKFKIWTDIEIYACEARANRGEVPKEDLETIKQ
KAKFNVDEILEIESKVHHDVIAYLTNLNSYIGPAGRHVHFGLTSSDVGDT
ALCVQMVQAMDLLIQRTETLLETTKQKAKEYKDLPCIGRSHGIHAEPMTL
GLKFALFFAEMTRNLERMKDAREQVAVGKLSGAVGTYSNIDLEIEEYVLN
KLGLKVDPIATQVISRDRHAFYMSVLGVVAASLDRMATEIRLLQKTEGRE
VEEPFAKGQKGSSAMPHKRNPVVCERISGISRVIRSNVNVGLQNVGLWHE
RDISHSSAERIVLPDSTIALDYILEKMNFVLKGLHVYPDATERTLNVTRG
LIFSQKVLLWLIEKGGITREDAYLIVQENAMAVWADQSKNLRDLLKQDPR
CSSILKDSDLDEIFQIKPYLERIPLIFKRLGIID
>LBF_1870 purC, Phosphoribosylaminoimidazole-succinocarboxamidesynthase
MIPNPHYKGKVRDVYDLGDKLLLVATDRISAFDVVFSEPVEDKGKILTRI
STNWFRYFSNIPNHLVTDDPNLFPKPYQNEPSLLGRSVLVKKAKRIDFEC
VVRGYLTGSAWKEYLQSGTIAETPYPKGIQESFQFPSPIFTPARKNDSGH
DENVSEETMEREVGSVLFQKVKQISLRLYEEAHDLMAKQGILLCDTKFEF
GLIGDEPILIDEILTPDSSRYWDKSTYSLGKTPASFDKQILRNWLETTPW
DKNPPPPQLPESLIQELRKKYLELEEKINLCLSQK
>LBF_0244 purD, Phosphoribosylamine--glycine ligase
MDNQYKVLLLGSGGREHALADAISKSNVLESLKVYPGNGGFSEDVLLKAD
EISITDKSKFIEYIKSSQTNLVVVGPEDPLVNGIADWCEEIGVPCFGPSA
YCAQVEGSKHFAKEMMKRAKVPTASFAVFTDHESAWSFAQKEMLPLVVKA
DGLAAGKGVTVAFEMKDVKRALDEIFLESKFGQSGYKVVLESFLEGEESS
LFVITDGERYMCLPAAQDHKRAYDGDIGPNTGGMGAYAPAPIVTEAVLEK
VKSRIIEPMLDDFKRSGHPYKGLLYVGLMITKEGEPNVVEFNCRFGDPET
QCVLRLLDEDILPIFYASAIGNLPVRNLKLKQGSSAVVVLAAKGYPDSPE
KGMVLEIPPNEGNVVVYHAGTKRDNSSLLANGGRILGITSFGKTLKDAID
ECYTFLSTIKAPSTFYRKDIGRRAL
>LBF_1701 purE, Phosphoribosylaminoimidazole carboxylase, catalytic subunit
MTNPLPKVAVIMGSYSDWDTMKEACEILTEFGVPFEKEIVSAHRSPDRMF
QFAKNAKNNGFGVIIAGAGGAAHLPGMTASLTTLPVLGVPVLSKALNGMD
SLLSIVQMPKGVPVATLAIGTSGAANAGLLAVRILSLLDSSLSKKLEDYA
DQNREQALSKNDQLV
>LBF_0168 purF, Amidophosphoribosyltransferase
MILQSDKPKEECAIYGIYNSKEAANFTYLGLYSMQHRGQESSGIVSTDGS
HLYRYANMGLVANIFTQPKIKELIGDAAIGHNRYSTTGASFLRNAQPVRV
ESHLGPVALAHNGNLVNSWDIRNRLERDGSIFQTTIDSEVIVHLMAKSHK
TDLLEALCESLAQVRGAYSLLVLTPRYLIAVRDPNGFRPLVMGKRSDGAI
VFASETCAFDITDTEYVRDVEPGEMVVIDHTGMRSLYPFPKAKPSLCIFE
YIYFARPDSYIFEESVYKVRKSLGRQLARVMPVEADVVIPVPDSANIAAL
GYSEESGIPYQSGLVRSHYIGRTFIEPDQKIRDFGAKIKYNVVKEVVNGK
RVVIIDDSVMRGTTSRKIIKMIRNAGAKEIHFRVSAPPTVAPCYYGIDIP
THKELIASTHSIEEIQKYLRVDSLAYLTLDRMHKAVEGHKGGGFCDACFT
SNYPVEFQDHAGNQKSLFTEYATEE
>LBF_1416 purH, Bifunctional purine biosynthesis protein
MIQIKRALVSVSDKTGITEICSFLTKHGVEILSTGGTYDALSKAGIAVKK
VDEFTGFPEILHGRVKTLHPKIHGGLLGDTTNPDHVKQMESNGIVPITLV
IVNLYPFVKTVMKPDVTLEDAIENIDIGGPSMLRSAAKNHKNVVVLTDPK
DYESFQNEFTTNNGKISRETAFGYAAKVFSETASYDSAISSYFNKRLGIK
YPDKITFAFNKKQKLRYGENPHQDAAFYEPLFLKSQFEALQGKELSFNNM
LDFDAAFHVASLLPKNAVSIVKHLNPCGIAFGETVLESFELARKTDPISA
FGGIIGIHGRVEKESAEEITKNFVEGVIAESFSNEALEIFAKKPNIRLIP
IAKFDEALDELDLRSLHHGLLIQNRDYDLITKDKLKIVSKKQPTEDDLEG
LMFAWNCVKFIKSNAIVYTDQNSTLGIGAGQMSRVDSVELGAMKAQKVGL
SVVGSYVGSDAFFPFRDGIDAIAKVGAKAIIQPGGSIRDEEVIQAADEHG
LIMVFTGMRHFRH
>LBF_1702 purK, Phosphoribosylaminoimidazole carboxylase, ATPase subunit
MMKIGVLGSGQLGQMMCLEAIPLGHDFYCYSPDLNSPSEKLGAKATIASY
DSIQQLESFLQTIDVLSFEFENIPKPTLEFLKNQKLIAIFPPPQALIIAQ
DRFLEKNHFRKLGFETAEFFHLTKASSKFEISIPFPWIIKTLRFGYDGKG
QVKVNHQSEYESFLQSAFLKDESEYLIEEVIPFQKEISILLTRFQNGDIV
CYGAVENEHKNHILDLSIFPARIPVGLNLEAIEMASKLAESLHYVGTMGV
EFFLKNNQLYLNEFAPRPHNTGHFTQDCQSFSQFYLHVQAITGNTPPTDV
RPKPTLMKNILGNSFEESLEIASELQKDDRYRLHLYAKEEAKPGRKMGHL
NFKGSLEEVNPLFHDL
>LBF_2099 purL, Phosphoribosylformylglycinamidine synthase
MEKEKVSLADAKEHGLTETEFVEIQKILGRIPNSTELGIFSAMWSEHCSY
KNSILKLKTLPTKSDKLLAGAGEENAGAMDIGDGLAVVFKIESHNHPTAV
EPYQGAATGVGGIMRDIFTMGARPITSLNSLRFGDPKEPRNKYLLTRAVK
GIGDYGNSLGIAVGGGELFLHPTFTKNPLVNAMTVGIAKHDEMASASTKG
KVGNKVYIVGATTGRDGIHGASFASKDLTKESEEKRSAVQVGDPFMEKLL
MEASLEAIQKKLLVGIQDMGAAGISCATSEMSAKGKTGMDVDLDKVPLRE
ADMNAYEIMLSESQERMLVIPEVGKEGELVSIFHKWGLNAVEIGTVTADG
ILRIRKNGTLKAEIPAESLVLGGGAPRYVREEKRPTYLDEVVKFDPNKIP
DLKPDTVPQTLNSLLSSLNISSRRPLYEQYDTEVGLVKVVEPGEDGGLVR
IPGTKKGIAVATDCNSRYTYLNPYEGAQIAVCESARNVAATGAEPYGVTN
NLNFGNPYIPENYYVFSECVRGLGDACRFLGLPVTGGNVSFYNESPEGPV
FPTPTIGMVGVIDDVAKGLRTYPRTKEDVKYALVGNFQPTISASEYLYRS
QGLDTGAIPNISLEKEKQTMDALIECRKNGLLTSAKDLSLGGLLVALAKI
VIAGKKGVEVNLNELQTKVPRLDALCFGETGASFIVSFLPNDETKVRESF
TSKGLSVYTLGSSSAKASLSVKGDGFHWEWTTKSLEVEFESGLKSYFE
>LBF_0881 purM, Phosphoribosylformylglycinamidine cyclo-ligase
MSDQNKITYKDAGVDTEKGQEFVKRIKANVASTHNKNVLGGLGGFAACYD
VSFLKSYQEPILLSGTDGVGTKLQIARQLGIHNTVGIDLVAMCVNDILVN
GGKPIFFQDYIACGKLHLPTMEAIVSGIVKGCSLADCSLVGGETAEHPGV
MPDDEYDLAGFVVGVVEKGKMIDGKTISPGDTIIGLKSSGPHSNGFSLIR
KLLLKDGKLPTSQEQIDFIKDHIFVPTNIYVKSILSLIDKISIKGMVHIT
GGGFYENIPRVLPEGVGAEIFSLPESYVFSKLEKDHSLDRNDMYGTFNMG
IGYILVVDSSLVDATMNELHVLGEDSFVIGKTNDSGKISITL
>LBF_1417 purN, Phosphoribosylglycinamide formyltransferase
MGKTKRVVFLASGRGSNFSAAVESIQKKKLKLDILALVSDNPEAKALTIA
KNFGISTKVIPYGSYQSKSDYHRDLLRQVEAYDPDLIVACGYMRILKPEF
VQRFKNQIINVHPSLLPAFPGLDSQKQALDYGVKVAGCTVHFVWEGVDTG
PIILQKAIAIRPEWTEKELSLAILKEEHIILPLAIQLFCEDKLKIKERKV
EILK
>LBF_1869 purS, Phosphoribosylformylglycinamidine synthase
MFVAKINVTLKESVLDPQGQTVLRTLHDQGKLQIQDLRVGKYIEIKLNAS
SQKEAEEIAKGICESVLVNQVIETYKLVVESQ
>LBF_2651 purT, Phosphoribosylglycinamide formyltransferase
MIGTPFTKHATKLLLLGSGELGKEVAIEANRLGVHVIAVDRYPNAPAMLV
AQESRVINMLDPKELEATIRELKPDFVVPEIEAIHTETLVTLEKDGFKII
PSAKAVNLTMNREGIRNFVANELGLITSQFLFADTIEDFTNAVHTIGFPC
VVKPIMSSSGKGQSLVKTEADIIKAWEYGQTGGRTGKGKMIIEEFIPFDF
EITLLTIRHIDGTSFLPPIGHRQVNGDYVESWMPQPMSDLALTSAKNIAE
TVTTGLGGFGIFGVELFVKGDEVYFSEVSPRPHDTGLVTLISQNVSEFSL
HVRALLGLPIPELIFQTPAASSAILLEGNTKSPEYVGLKEALAIKGVDIR
IFGKPEVEGKRRMGVSLALGNTIEEAKEKANRGRDHIQLKT
>LBF_0992 pyrB, Aspartate carbamoyltransferase, catalytic chain
MYAYSHKNILDTLQFSKDDLNYLITKTNRMNALHESGKAFGILHGKLLAS
LFFEASTRTRMSFEAAMERLGGRLISTVGFQFSSISKGETLYDTMKMIEA
YCDIAVIRHPVEGSSRIAAGAVNIPVINAGDGAGQHPTQALLDLYTIVSE
KGKIDGLNIAFIGDLKYGRTIHSLINLLRHYPVHLYLISPEELRLPEKYK
KNLEGFPMTWEETTDIKAIWDADVAYVTRIQEERFPDHREYEKLKDIYKV
NKELVLASKKDTTILHPLPRVNELSTDVDDLPNAAYFRQAKYGVVVRMAL
LCLSLGVNFD
>LBF_0092 pyrD, Dihydroorotate dehydrogenase
MFYHQLIKPILFHLDPESAHHLVATFLSLSKKIPFFHKTLSAIFQFSSKR
LEQTIQGIHFPNPVGLAAGFDKTTELFPTMIHMGFGFIEIGTITAKAQPG
NEKPRLFRYPKVKALINRMGFNNPGADQAEINLKNQQKLGVRGINAGKSK
VTALEDAVGDYVYTLKKLVPFGDYAVINISSPNTPGLRSLQTKQSLIDLI
QGIQKEFQNSFPIPLYLKFAPDLTEEELIENLKVCLEYKISGVILTNTTL
DKQSLGELNPEEGGLSGGPLFQKSLRFVSLAYQTLQGKIPIIGVGGIDSG
EKALQMMEMGANLIQIYTGYIYEGPFLPYQICSYLDKVVKDRGYQTISEL
VGSGNSK
>LBF_2358 pyrE, Orotate phosphoribosyltransferase
MSHSHRDALFQWMKTYVYRHSETPFRLASGLESQHYFNCKEITLHPERLS
ILAECFIEEIIPKLNIEFQAVGGLTLGADPIAYAISLGYQKRGKNVFPLV
VRKESKGHGTGQQIEGFWKDIKTCLVVDDVITTGGSTLKAVKVLREVGIN
VTKGICILDREEGGSENLQTENVTMTSIFAKSEFF
>LBF_4107 pyrF, Orotidine-5'-phosphate decarboxylase
MTSFLSKFRNRRDGLRSQLCIGIDPELEKLPKVCLDSKSPLVHFSETIVR
YTHPYAVAWKPNIAFFERLGAEGYFALEHMVHLMKEVSPEVPIVMDAKRG
DLANTAKEYAKYFFQTLKVDALTVNPYMGRDSLTPYLDLGGYLFVLGLTS
NPSSSDFQKLKTKTNDLYLYEEVSDQMASLSEVYPGQVGLVVGGTHPSEI
QSLRKRHPDLCFLIPGFGAQGGDLESIIHASGKEALINSSRGITLSSLAE
NYGEVSKKKSEEVHLRMNHLFP
>LBF_1595 pyrG, CTP synthase
MSKTRYIFITGGVSSSLGKGVTVAALGCLLEARGYTVSLQKMDPYINIDP
GTMSPYQHGEVYVTEDGAETDLDLGYYERFTKSKFSRKNSVSTGQIYHAV
IERERKGDYLGRTVQVVPHITNEIRSRIYNLTRDQETDFVIVEIGGTVGD
IESIPFLEAIRQMRYEHGNQQVLFLHLTLVPTITAAGEAKTKPTQHSVKE
LLALGIQPDVLICRINKPMSKEMKNKISLFCNVKEQNVISAVDITTSIYE
IPLMYREDKLDEVVLNALGMDLRKLNFSQWENMVKKIRNTKKTVKVALIG
KYISLQDAYRSVYESLAHGGIANDVEVSVVKINPEDIDSKNIKELLKGVH
GVLVPGGFGERGIEGKIAAIQYARTKNIPFFGICLGMQCAVIEFARNVLG
FKDANSTEFKPNVQYPVISMIEEQKEIERMGGTMRLGAYPCLVKKGSLAH
SEYKSDRISERHRHRFEFTLRYKDDFEKKGMNLTGFSPDGSLAEIVEIPN
HPWFIGVQFHPEFQSKPTDPHPLFAGFIKAASKLAKKTED
>LBF_2535 pyrH, Uridylate kinase
MGTSPRFKRILIKISGEALAGEGELGIDTNKTFSLAGQIKEVHDLGLEVA
VVVGGGNMIRGETLAKSGMDRATADYMGMLGTIMNGLALQDACEKQGMFT
RVLSAIEMKSVAEPYIRRRAVRHLEKNRVIIFAGGTGNPYFTTDTTASLR
AVEVGCEVILKATKVDGVYTADPKKDPSAKRYLQVSFMESIKHRLKVMDS
TALSLCMDNNMPIIVFDIFKAGNLRKLIDGEPIGTLISNSEEVILDGR
>LBF_1214 tmk, Thymidylate kinase
MPFKSQFFVFEGIDGSGKTTVSKKVSEILSTKSISNLWHREPTDSIHGQK
IREFLQGKIKLTPDEQLKLFLLDREFSVNETILPTLKSDTCLVQDRYYFS
TAAYQGRDEEHAADILYMNEDKGFPEPNRVYFLDLSPEEALERRNTRGGN
KEAFDDEKEQTRIYQNYLAILPESTIFVDATADLEEVVNFCVEDILLSLS
LKT


# Leptospira biflexa serovar Patoc strain Patoc 1 (Paris), Patoc 1 (Paris)

>LEPBI_I3460 Putative cytidine/adenosine deaminase
MDFYESFLKRYSIEVSKYKNEIPSYSEIITKDGNLVSSSFNSVEQTLNPT
KHSEILAIEKALSHVDGRYLSEHILITALEPCILCAGAVVRVKLPEVVYF
LPAKPGEGISSYTTESIYLLNHFPKCTLIPESRIKFEFLSFFKEKR
>LEPBI_I1763 Putative hydrolase
MSKSLQSFNPSRRLKVSMSSYEEHSIRKNLFSIGKLGYAKGDRPNVECIL
CGVRDKNEIVPNLTIAETDLSIVSINLFPYNPGHIIIFPKRHIIHYLELT
DEEALDIHRLTQKTMRILEQQWKVQGFNTGYNLGKNSGGSIPHIHEHIVP
RFPNEAGFLDVLSNTRIVIYEPYQMWEDLKKLWVKEEN
>LEPBI_I1495 Conserved hypothetical protein with HIT motif
MEDCIFCKIIRGEIPAKKEYETDSIFVFHDITPQAPIHLLIIPKAHIKSM
NEIDSLDPKVIHQIFEVIPELAKKNGIFEKGYRVVNNCGTYGGQTVGHLH
FHLLGGRHLQWPPG
>LEPBI_I2667 Putative HAM1-related protein
MQMLLSPFGYEIVTPKILGIPFSPEETESTFVGNSFIKSKELFRLTGFPS
FADDSGISVDALGGEPGVLSARFGGPGLSDKDRALYLLNKLGTNHNRKAH
YSCVVSFVDANHQVSFEGKVEGLIASDYDELGKFGFGYDPIFYYPEFGKR
FSEVPEGEKNKVSHRKKAMELFLEWFQTIQ
>LEPBI_I0071 Putative S-methyl-5-thioadenosine phosphorylase
MANVVKIGVIGGTGLYSIDGMEILKEIHPDTPWGKPSDTITIGRFKGKEI
AFLPRHGKGHFLNPSEVPARANIAALKQLGVEEIIAFSSVGSLRQEIAPR
DFVIPSQIIDRTKSRHATFFENGMVAHAPFADPFSSGLAKKVEEAAKQIN
LPIHTNKTLICMEGPLFSTRAESHMYRSWGADIINMTVLPEAKLAREAEI
LYQMVCMSTDYDCWKEDEAHVTLEMVLANLSTNADTAKKLLSTLIDLLGK
SDDTSLVGSTKFSLVTAPEKRNPEQINKLKFLFPSYF
>LEPBI_I2860 Putative glutamine amidotransferase, class-I
MRAVIIRFIDCEGPGILEPILREKGYRISYQNAFDSRVQLMPEIHLNFDL
IIMLGGPQSVADPDEQEFFKPYYEIVENVAVLPNKKLIGICLGSQIIARA
LGANVRPGTKGPETGFSDLQILKPEHPIFSGLNGDSLLAFHLHEDIFDIP
VGAEHLLASEFYANQMFSYKNKIFAFQTHLEPTLEMLHVWQNVHKEFIAK
GTGDFSNLKSKQKTMEESAKILFRNIINL
>LEPBI_I1480 Deoxyguanosinetriphosphate triphosphohydrolase-like protein
MKKGRNELLNDEEKILATYAVGSRNFGGRAYEEPEHPYRLPFQRDKDRII
HSHAFKRLEYKTQVFVYSEGDHFRNRLTHTLEVAGISKTISKVLGLNEDL
SESIALAHDLGHSPFGHAGQEALAELMKDIGGFEHNKQSLRVVQKLERRY
PNFPGLNLCEETLLGIMKHGGGYESSNLLEVRRTLGPSLEAMIVDASDEI
TYSAHDLEDGLESGLLQLEEVKGLMIWKRIDESLPSSEKNSKTEMLSISR
SIGRISLNLMVSDLIESIHKILTEYSVNSRESISKLYQKKIKIVQFSEEF
QKEFNELKQFLFQNLYRHSEVSRMSERGKETIYLLFKHFESHPESIPESY
RNREEEDGRMRVICDYIAGMTDRYAIEKLKREGILWFPY
>LEPBI_I1151 Putative deaminase
MTRPILLQSASMYQNGKMETKDIVFTGETITKIEDSIPSNNVMFSISLKG
KKLYPGFINSHDHLLASYLPKVGGTEKHLSWLSYDNLYKSSGVFAERQQI
DPEILYYLGAYKNLFAGVTSVFDHIPHFVQNPFRGILPVKLISDYTLAHS
VGNYSLDWGEGPALEYRMAEHANLPFVTHLAEGLDDDSKQSLRYLEKMDA
LGAHSVLVHCLPFGPKEADKIAEKGASVVWCPTSNLHIFGKTTNIKLFLE
RGVNVCLGTESSPSGSNHFLEEIKTAKSIYFGLYGEELSDSDLFKMITEN
PRKAFRMGNPNALMPGLKCDFVVVNDEKKSTELNVSDLHWKHIDLVVIDG
YPIYGSSEFLSLFQEFGLSTEEFVIDGKNKLVAGSPKKLMKQVSESVGYK
KSLAFLPNF
>LEPBI_Ia1510 Putative histidine triad (HIT) protein
MGRMMTCPICQAHKNPSEILFENEFWILRKANQNLDGYLYLEIKGHIESW
NQLTMEQFEAYGRALHKGTELIESSHPEKIYMTAIAERVPHLHVHLIPRF
KGQTPGIEHIAQATGPGFPKPM
>LEPBI_I0154 add1, Adenosine deaminase
MFRIGKKNPNPRWHLYLDSYEKAYGTKIRPSTFFDDYADKNEFAKLYHFL
EKAPFLHFQAKFNLIIALVKFDEPEITEVSHDVVFSNSLEDISYAEYRLM
FGKEEPKESFYSKLMASLEGLKKGEESAKKAGKPIQGKLVMSLHRDLNFE
RHYDWMKNWMEKESVIRDGLVGIDFCHIEEGHPPKDKRLFFQSIQKDNKA
EPNTALSILYHVGESFRDKTPFSAVRWILESAEYGAHRLGHALALGIDSD
YFLGEERTEFVSEAKDQVEHELMYFDEITTYGPFYAKEELEIKRKEYKTK
PDTEILTIPFDETQSQYLHTFQNYAMSKIAKSNAVIECCPSSNLYIGMLE
SHIDHPITRFLQNDLKLTIGSDDPGLFGTTMAEEYHHAHTAGVSDKDLEI
LRSVSLDYRSTKLSGRELD
>LEPBI_I0038 add2, Adenosine deaminase
MYALTKFSILSWNMEVPFSEILSRISVIDRDIAELNRLKSRLPADRPYSP
TIQLTFDKQINTLLNERVSLMELPILHPPLWLLPKEGAEGLEQTTLLKER
KSLLAGDLSVAHPNEQDVINFIREIPKTEVHLHLEACVNKETLKFLYKKN
GIEVTDQEFEDKYNFKDLNGFIQVFFFVQGSVKEASDLGYFIDSLADYLR
SNHIVYCEAFFAPSKFIQNGLDFDEMVEVMVNRIRQIEVKDGISIRLLVD
VSRSFGPENAMNNLKRVLGLKQKEVIGIGLGGAELMGPAKDYAEVFKIAR
ESGLRCVAHSGEDDGPWAIWDAVNLCKAERIGHGTSAIQDPELVRYMKEN
KIPIEICVTSNVFTGKYVRKEQNHPVRYYYDQGLMLCINTDDPDIFNVNL
TYEYFKLYRFLDFSIDELIDLVRQGVLCTFHPEKETLWKSMEEKIDLIKL
KYNLNSEKQVLSV
>LEPBI_I1944 adk, Adenylate kinase (ATP-AMP transphosphorylase)
MKRLIFMGPPGAGKGTQADIIKEKYNIPQISTGDILRAAVKNGTAMGIEA
KKYMDAGDLVPDAVVIGIIRDRLVEADCANGFILDGFPRTVEQAKALSEI
LKELHMELDSVVNLDVPDEELVKRLLGRAIKEGRSDDNEETIKNRLHTYN
TKTLPLIDFYKATGILRQINGLGSMEEITNTILKSI
>LEPBI_II0127 apt, Adenine phosphoribosyltransferase
MMERSAFAGLFLLQDPSLPWFHPFMSIVKSKIRTIPDYPKPGILFRDITS
LLIDPEGFQLTIGMFVERYQNAKLNKIAAIDARGFIPGAALAFQLGVGFV
PIRKKGKLPGNTISESYALEYGVDHVEIHTDAIVPGDKVLIMDDLIATGG
TLEASIKLIQNLKGQIHECSTIINLPDLGGAKRIKDTYGIDVFSICEFEG
H
>LEPBI_I0815 carA, Carbamoyl-phosphate synthase, small chain (Carbamoyl-phosphate synthetase glutamine chain)
MFASLAQFLGMDLMQAFLVLANGTVMKGRSFGANKNSIGEVVFNTSMAGY
QEILTDPSYKGQLVTLTYPMIGNYGINPDDMESDRIQASGLIVKEYVKRP
SNFQSKETLSEFLIRFGVPAIEGIDTRKLTRIIRNSGAMNCGIFISETYE
DSFLETVKNAPSMEGQDLAQIVTCEKPYVFGAHSPSKFKLAVYDFGIKRN
ILRLLDSAGFNVHVFPAKTKAEDLLKEGFDAFFLSNGPGDPAPLDYAIQS
AKTIMDAKKPLFGICLGHQIIGLALGKKTAKLKFGHRGGNHPVRNEETGK
IEITSQNHGFHVLGESSEDMPITRLNLFDNTVAGLKTKGLPVMAVQYHPE
ACPGPHDSAYHFQEFYTMVETSKG
>LEPBI_I1281 carB, Carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain)
MPQRNDLKSILIIGSGPIVIGQACEFDYSGTQATKALREKGIRVILVNSN
PATIMTDPDLADATYIEPLTVPVLEKIIKKEKPDAILPTVGGQTALNLAL
ALHREGVLEKYNVELIGAKVDAIRKAEDRELFKLAMEKLGIRVAKSFMVS
DMEAARKAKDEIGFPIIIRPAFTLGGTGGGTCYEESEFEEIAQKGLSASP
ISQILVEESVMGWKEFELEVMRDLNDNVVIICSIENLDPMGVHTGDSITV
APQQTLSDKEYQRLRDMSIDIIREIGVETGGSNIQFAVNPENGDVIVIEM
NPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIRNDITRVTPASFEPS
IDYVVTKIPRFAFEKFPGSDNTLGVQMKAVGEAMAIGRNFKESFQKALRS
LETDRFGFGSDGYLKELMEWETVPKEQRHEWLTARVKRPTDKRIFYVKMA
FDFGMSVEEIHEICKIDPWFLYQFEELFQLENKYRKDGNTIIEEMKQAGF
SNRQLAFLSKEEQILAQVRSGAAIEITKAKVEKTLREEEEKIESYLEEKN
IHPVYKRIDTCAGEFEAFTPYMYSTYDEEDESDVTSKKKVMILGGGPNRI
GQGIEFDYCCCHASFSLQEAGVESIMVNSNPETVSTDYDTSDRLYFEPLS
LEDVMAIFKKERPDGVIVQLGGQTPLKLAKSLEKRGVPILGTSPDSIDRA
EDRKRFAEVLEKLNLKSPENGIASSKDKAREIARKIGYPVLVRPSYVLGG
RAMLIVNEETELDKYMEEAEEVSEDRPLLVDSFLQDATEVDVDALCDGKD
VFIAGVMEHIEEAGIHSGDSACVLPPQSISQRMIQEIEEATLRLALELDV
KGLINVQYAIKDETLYVLEVNPRASRTVPFVAKSIGIPIVKIAVRLMLGE
SLASFKLGKRFSAPMITVKEAVLPFSKFPGVDTILGPEMRSTGEVMGVAA
TKGEAFVKAQIMAGEEPPKHGTVFVTINDKTKKELLESVRSLSNLGYNII
ATEGTHKFLSDNGILSSKINKIYDGYFPNVIDYIKEKKIHLIINTPLSRV
TRENAFTIRQAAIKYKVPCLTTAQAAKALIHGLVEMKDKGFSVNSLQEIH
KKK
>LEPBI_I2596 cmk, Cytidylate kinase
MSLQSIENVIAIDGPAGSGKSTLARMIAHKLGFHYLDSGAFYRALTFALL
EKFKETKEDESKFPFYTEKLADATLLEKDESEFGFSVAAIPVHCELSSTG
ENLMFLGERDISREIRDPEITKKIRYIAPRRAFREILNRHIREFAKTHRL
VMDGRDIGTEVFPKSKFKFFLTASVEVRAKRRYDELVTKGFKADLNHIKE
EIVARDESDTTRTVAPLKQASDAILIDTSTLDTETVLNTILSKVSPSGQI
>LEPBI_I3246 dcd, Deoxycytidine triphosphate deaminase (dCTP deaminase)
MILTGKEILKRLGSDIKIEPYDEKLLNPNSYNLRLHEDLLVYSEFPLDMK
KPNPVRTLKIPEEGLLLEPGNLYLGRTIEFTETHNLVPMLEGRSSIGRLG
MFVHITAGFGDVGFKGFWTLEIQVTHPLRVYSGVQICQIFYHTVEGEISE
YKSGKYQANQGIQPSLLYKDFEKK
>LEPBI_I1531 dut, Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase; dUTP pyrophosphatase)
MLEPENYLQIQILKEGAVLPEYKTPGAAGMDLSACLSENLLLPKGEVVLV
PTGLAMAIPEGYEGQIRPRSGFSTKHRIIMPNSPGTIDSDYRGEILIPLL
NLSGEDFVLKPGTRVAQLVIQAVSQLPIQVVTGLDATQRGTGGFGSTGK
>LEPBI_I0951 gmk, Guanylate kinase
MKAVPNLYIISSVAGGGKSTIIQALLKENPEFYFSISCTTRDPRPGDEEG
KTYYFLTIPEFQKKIADGEFYEWAEVHGNYYGTPKAPILDAIKEHRVALM
DLDVQGAKSVKQLRPESVTIFIEPPSREIWIERLIRRGTDSKTSIEKRIE
NGIIELDEAPSFDYVVINDRLEDAITEVKAILCGTKS
>LEPBI_I1615 guaA, GMP synthetase [glutamine-hydrolyzing] (Glutamine amidotransferase; GMP synthetase)
MTSDKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPLSRYESYAGII
LSGGPSSVYETGAPLLPAGFFDTSVPVLGICYGHQLMMKTLGGEVVSAST
KEYGPAILEIENPNSPLSQSLSLKTKVWMSHGDEVVRLPNDFQVIAKSDH
CRYAFVSHPSKNLFGIQFHPEVTHSEEGEILLKNFVELCGASGTWSIQHF
LDEQIQSLQKKVPEGKNVFLLVSGGVDSSVAYLLLAKALGKDRVKGLLVD
TGFMRKNEVKDLMDNLHHVGFDLTIWDESEVFYKSLQNEFEPEKKRRIVG
DLFLEAQGKATTSLGLDAEHWLLGQGTIYPDTIESGGTKHSHKIKTHHNR
VPQIEALIREGKIVEPIADLYKDEVRELGRTLGLPERWIERHPFPGPGLV
VRMIASPRTSPPNIDFSIWKEKIPKAEIQILPILSVGVQGDQRSYAHCAV
LSDFTSDWKELDNLSVEITNTKKEINRVVLAPGITHFEKDFFYTKLTLDK
THADILRDADAIVNQILYDESIHNQIWQMPVVLVPVGLRENSYGVVLRPV
ESTEAMTANFYQMNRNILARITKELLELPQISLVMYDLTHKPPGTIEWE
>LEPBI_I1272 guaB, Inosine-5'-monophosphate dehydrogenase
MSNHPLPGTELLDGVSGQELFSVNMGLTYRDFLVLPGYIDFNPSDVELET
KLSKNISLKRPLMSSPMDTVTESEMAIAQALMGGIGIIHYNNTIEEQVDL
VRKVKRFENGFIKDPILLSPEHTVADLDAVKEKYGFSGIPITENGTANSK
LVGIVTNRDVDFEKDRNIKLGKVMTTELITANVGISLLEANDILRTSKKG
KLPIVDKQGKLVALICRSDLKKNKEFPQSSKDDQKRLRVGAALSTLPESR
DRMAALAGVGVDAIIIDSAQGNSSYQIEMIQWIKSNFPNIDVIGGNVVTK
AQAANLIGAGADGLRIGMGPGSICITQDTMAVGRAQATAVFKTAEYAQAH
GVPVIADGGISNIGDIANALAIGASMCMMGSMFAGTKEAPGEYFYENGIR
LKKYRGMASLEAMSKGGDKRYFSESQKIKVAQGVSGYVVDKGSVLNLIPY
LVQGLRQSFQDMGYRNIPDLHKALREGKLRFERRTESAQAQGSVHGLYSY
TKPSMRAE
>LEPBI_I3157 hpt, Hypoxanthine phosphoribosyltransferase (HPRT)
MKPLYSEERIHQRVEELAREISRDFLSKDLVVIGILNGGFIFTADLCRSI
AIPHEVDFMGASSYGDGTSSGDFKITKELKKSIQNKSVLLVEDIVDTGKT
LEYLLLEVQKQNPKDLKVAALFWKQKKANPHIIVDYPGFIIEDDFLVGYG
LDFQGKYRNLPYVAKLEGTD
>LEPBI_I0084 ndk, Nucleoside diphosphate kinase
MERTFIMLKPDAVKNKHIGDILQRIEKEGFKILGMKFLKLSLEDAKQFYA
VHAARPFYNDLCTYMASGPIVACALERDNAVAHWRDVIGATDPKEAKAGT
IRALFAESKEANAVHGSDSVANALQEIAFFFKGYELN
>LEPBI_I1686 nrdA, Ribonucleoside-diphosphate reductase alpha subunit (Ribonucleotide reductase)
MKIERHFTKGNKGLYPNLTWVRKDSKITNTDGSVVFEANGVEVPDFWSQV
ATDILAQKYFRRKGVPKYLKKVSEKGIPEWLQRSVPDDEKLAALNPEDRY
VGELDSKQVFHRLAGCWTYWGYKYGYFTEEDSARVFYEEVIFMLASQMAA
PNSPQWFNTGLHWAYGIDGKSQGHYYVDPKSGKLVRSASSYEHPQPHACF
IQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRAANESLSGGGK
SSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDMDHPDIEEFIDWKVQE
EKKVASLVTGSILNNRLLNDIMSACASAKQSLGEEKAYDPAANVELKKAI
QKARKAFVPDNYIKRVIDLSKQGYKDLLFEELTTDWQSEAYNTVSGQNSN
NSVRITNEFMEAVEKDLPFHLINRTEKENARKDGREPKAAKTLRARDLWE
RIANAAWNSADPGTQYHSTINEWHTCPEDGAINASNPCSEYMFLDNTACN
LASANLVKFLKEDGTFDVEGYRYLNKIWTIILEISVLMAQFPSKEIAELS
YKFRTLGLGYANLGSLLMIMGIPYDSQEAMAVTGAISSIMHMTAYATSAE
MAKELGPFAGYEKNKNHMLRVIRNHRRAAYNAPKEEYEGLTITPVGINPS
FLPSYLLEAAKEDSDRALELGEQYGYRNAQVTVIAPTGTIGLVMDCDTTG
IEPDFALVKYKKLAGGGYFKIINQSVPAALKKLGYSQAEQDAIVNYCKGH
ATFNGAPGVNTARLKEKGFTEDVLEKLEKQLPFVFDIQFAFNKFTLGEDF
LAKTLGIDPSLYNSMGFNLLETLGFSADEITQANDYVCGTMTIENAPFIK
EKDLPVFDCANKCGKYGKRFLSYQSHIRIMAAAQPFISGAISKTINLPEE
ATIEDVKNAYLMSWKVMIKANALYRDGSKLSQPLNSVFQLLSAVGEDEEE
LQTSSAPKTVTEVAEKLVYKYISERRKLPHRRAGYTQKAMVGGHKVYLRT
GEYEDGQLGEIFIDMHKEGAAFRSLMNAFAIAVSLGLQHGVPLEEFVEAF
TFFKFEPNGMVSGNPHIKMSTSVIDYIFRELAITYLGRYDLAQVSPDDLR
TDEVGRKAEPAKDNVGKLESSGPRTPLPVNAISMKSVLEDKQEVVVAVAG
QSTQPTQAQSAAATLKIIAEARTKGYTGDSCTECGSFQMVRNGACLKCIS
CGSTTGCS
>LEPBI_I0447 ppx, Exopolyphosphatase (ExopolyPase; Metaphosphatase)
MLPFSQILRKPNQAFRSEKILAAIDLGTNSFHIVVVKLRPDGTLEYLTKE
KESVRLGSGSSDYAVIKDDAIERGIACLKRFKTLADSYKAEIRAVATSAL
REAENRQVFLDRAEKETSIQIQVISGNEEARLIYLGILQGLPVFDKRILL
IDIGGGSTELLIGEKGEILFSTSMKLGAIRLTEKYLKKDPLSATDLQKCR
IHIESVLSAFLPQIERLKPFLVVGSSGTITSVTSMVLEKKGEKRERLNGT
EITIDLFKEIRKQVLDAESIKKRLKIPGLDAKRGDIIVGGVLVLDEVLQR
IKAPSFTVSDFALREGIVYDTIESWYRHTDTSLPRLDNIRDKAIKTVANL
YPQGKKHAEAVTKLTLQLFDDLTNLHGLGNLERDYLETACYLHQVGLCIS
HHNYHKHSYYIIRNSEAMVGFSNAEIEIIALLARYHRKGGPKGKHEEFKN
LRPEDQLLVKKLASFLRIGDGLDRSEKSIIDRLDAVVEKGKVSCRLYFKK
NEDPNLEIWSVSEKKDLFEDTFSTTLEFHLHPI
>LEPBI_I0236 prs, Ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase)
MNPSEVVVFSGNANRPLAEEICKNLKIPNGQISVKRFSDGESSVKIEENV
RGRDVFVVQSISYPANDSLMELLLIIDAARRASARRITAVIPYYGYGRQD
RKVEPRVPISARMVADLIETVGPDRVLTMDLHADQIQGFFRIPVDHLYFS
PVLAEYINSLGMDDLVIVSPDSGGAERARNFGKKVNGSLAIIDKRRPKAN
ESVVMHVIGDIKDKNCLLLDDMIDTGGTIAKAATALYENGAKSVLCCASH
GVLSGEAPSKLNEAKFNPIVLSNSIVIPESKKINHLKTLSIAPLFAKAIE
RIHNEESISSLFS
>LEPBI_I1934 purA, Adenylosuccinate synthetase
MPANLVVGAQWGDEGKAKVIDYLSKDTDIIVRYQGGANAGHTVVVGGKKY
IFHLVPSGIIYDNTTCVIGNGVVLDPEYFLKECADLETHGFRVKDKVLIS
DSCHILLPYHRLIDEAREAGSSPERKIGTTKKGIGMCYADKMLRNGVRAG
DLLDKENLKRKLNHILEVKNQELVKYYDLEPVNPNEMYDFLLDFADKMGK
NIINTVYYLNSELEKGKRVLLEGAQGTGLDIDFGTYPYVTSSNPTTGGAL
AGSGVSFRYLKDVIGITKAYATRVGEGPFPSEILGEAGDVLRKLGGEYGS
TTGRPRRCGWFDVQMIKHAVTVNGINSLVLTKIDVLSHYETIPVVVGYEY
KGKKLDFFPSQGLEDVKPLFAEYKGWKDDISGINSFAKLPPLCQSYIKSL
QELVNTKIGIVSTGPDRDHTIIMD
>LEPBI_I0049 purB, Adenylosuccinate lyase
MIDRYSHPEISAIWELENKFKIWTDIEIYACEARANRGEVPKEDLETIKQ
KAKFNVDEILEIESKVHHDVIAYLTNLNSYIGPAGRHVHFGLTSSDVGDT
ALCVQMVQAMDLLIQRTETLLETTKQKAKEYKDLPCIGRSHGIHAEPMTL
GLKFALFFAEMTRNLERMKDAREQVAVGKLSGAVGTYSNIDLEIEEYVLN
KLGLKVDPIATQVISRDRHAFYMSVLGVVAASLDRMATEIRLLQKTEGRE
VEEPFAKGQKGSSAMPHKRNPVVCERISGISRVIRSNVNVGLQNVGLWHE
RDISHSSAERIVLPDSTIALDYILEKMNFVLKGLHVYPDATERTLNVTRG
LIFSQKVLLWLIEKGGITREDAYLIVQENAMAVWADQSKNLRDLLKQDPR
CSSILKDSDLDEIFQIKPYLERIPLIFKRLGIID
>LEPBI_I1925 purC, Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase)
MIPNPHYKGKVRDVYDLGDKLLLVATDRISAFDVVFSEPVEDKGKILTRI
STNWFRYFSNIPNHLVTDDPNLFPKPYQNEPSLLGRSVLVKKAKRIDFEC
VVRGYLTGSAWKEYLQSGTIAETPYPKGIQESFQFPSPIFTPARKNDSGH
DENVSEETMEREVGSVLFQKVKQISLRLYEEAHDLMAKQGILLCDTKFEF
GLIGDEPILIDEILTPDSSRYWDKSTYSLGKTPASFDKQILRNWLETTPW
DKNPPPPQLPESLIQELRKKYLELEEKINLCLSQK
>LEPBI_I0251 purD, Phosphoribosylamine--glycine ligase
MDNQYKVLLLGSGGREHALADAISKSNVLESLKVYPGNGGFSEDVLLKAD
EISITDKSKFIEYIKSSQTNLVVVGPEDPLVNGIADWCEEIGVPCFGPSA
YCAQVEGSKHFAKEMMKRAKVPTASFAVFTDHESAWSFAQKEMLPLVVKA
DGLAAGKGVTVAFEMKDVKRALDEIFLESKFGQSGYKVVLESFLEGEESS
LFVITDGERYMCLPAAQDHKRAYDGDIGPNTGGMGAYAPAPIVTEAVLEK
VKSRIIEPMLDDFKRSGHPYKGLLYVGLMITKEGEPNVVEFNCRFGDPET
QCVLRLLDEDILPIFYASAIGNLPVRNLKLKQGSSAVVVLAAKGYPDSPE
KGMVLEIPPNEGNVVVYHAGTKRDNSSLLANGGRILGITSFGKTLKDAID
ECYTFLSTIKAPSTFYRKDIGRRAL
>LEPBI_I1754 purE, Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase; AIRC)
MTNPLPKVAVIMGSYSDWDTMKEACEILTEFGVPFEKEIVSAHRSPDRMF
QFAKNAKNNGFGVIIAGAGGAAHLPGMTASLTTLPVLGVPVLSKALNGMD
SLLSIVQMPKGVPVATLAIGTSGAANAGLLAVRILSLLDSSLSKKLEDYA
DQNREQALSKNDQLV
>LEPBI_I0173 purF, Amidophosphoribosyltransferase (Glutamine phosphoribosylpyrophosphate amidotransferase)
MILQSDKPKEECAIYGIYNSKEAANFTYLGLYSMQHRGQESSGIVSTDGS
HLYRYANMGLVANIFTQPKIKELIGDAAIGHNRYSTTGASFLRNAQPVRV
ESHLGPVALAHNGNLVNSWDIRNRLERDGSIFQTTIDSEVIVHLMAKSHK
TDLLEALCESLAQVRGAYSLLVLTPRYLIAVRDPNGFRPLVMGKRSDGAI
VFASETCAFDITDTEYVRDVEPGEMVVIDHTGMRSLYPFPKAKPSLCIFE
YIYFARPDSYIFEESVYKVRKSLGRQLARVMPVEADVVIPVPDSANIAAL
GYSEESGIPYQSGLVRSHYIGRTFIEPDQKIRDFGAKIKYNVVKEVVNGK
RVVIIDDSVMRGTTSRKIIKMIRNAGAKEIHFRVSAPPTVAPCYYGIDIP
THKELIASTHSIEEIQKYLRVDSLAYLTLDRMHKAVEGHKGGGFCDACFT
SNYPVEFQDHAGNQKSLFTEYATEE
>LEPBI_I1469 purH, Bifunctional protein: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MIQIKRALVSVSDKTGITEICSFLTKHGVEILSTGGTYDALSKAGIAVKK
VDEFTGFPEILHGRVKTLHPKIHGGLLGDTTNPDHVKQMESNGIVPITLV
IVNLYPFVKTVMKPDVTLEDAIENIDIGGPSMLRSAAKNHKNVVVLTDPK
DYESFQNEFTTNNGKISRETAFGYAAKVFSETASYDSAISSYFNKRLGIK
YPDKITFAFNKKQKLRYGENPHQDAAFYEPLFLKSQFEALQGKELSFNNM
LDFDAAFHVASLLPKNAVSIVKHLNPCGIAFGETVLESFELARKTDPISA
FGGIIGIHGRVEKESAEEITKNFVEGVIAESFSNEALEIFAKKPNIRLIP
IAKFDEALDELDLRSLHHGLLIQNRDYDLITKDKLKIVSKKQPTEDDLEG
LMFAWNCVKFIKSNAIVYTDQNSTLGIGAGQMSRVDSVELGAMKAQKVGL
SVVGSYVGSDAFFPFRDGIDAIAKVGAKAIIQPGGSIRDEEVIQAADEHG
LIMVFTGMRHFRH
>LEPBI_I1755 purK, Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase; AIRC)
MMKIGVLGSGQLGQMMCLEAIPLGHDFYCYSPDLNSPSEKLGAKATIASY
DSIQQLESFLQTIDVLSFEFENIPKPTLEFLKNQKLIAIFPPPQALIIAQ
DRFLEKNHFRKLGFETAEFFHLTKASSKFEISIPFPWIIKTLRFGYDGKG
QVKVNHQSEYESFLQSAFLKDESEYLIEEVIPFQKEISILLTRFQNGDIV
CYGAVENEHKNHILDLSIFPARIPVGLNLEAIEMASKLAESLHYVGTMGV
EFFLKNNQLYLNEFAPRPHNTGHFTQDCQSFSQFYLHVQAITGNTPPTDV
RPKPTLMKNILGNSFEESLEIASELQKDDRYRLHLYAKEEAKPGRKMGHL
NFKGSLEEVNPLFHDL
>LEPBI_I2154 purL, Phosphoribosylformylglycinamidine synthase II (FGAM synthase II)
MEKEKVSLADAKEHGLTETEFVEIQKILGRIPNSTELGIFSAMWSEHCSY
KNSILKLKTLPTKSDKLLAGAGEENAGAMDIGDGLAVVFKIESHNHPTAV
EPYQGAATGVGGIMRDIFTMGARPITSLNSLRFGDPKEPRNKYLLTRAVK
GIGDYGNSLGIAVGGGELFLHPTFTKNPLVNAMTVGIAKHDEMASASTKG
KVGNKVYIVGATTGRDGIHGASFASKDLTKESEEKRSAVQVGDPFMEKLL
MEASLEAIQKKLLVGIQDMGAAGISCATSEMSAKGKTGMDVDLDKVPLRE
ADMNAYEIMLSESQERMLVIPEVGKEGELVSIFHKWGLNAVEIGTVTADG
ILRIRKNGTLKAEIPAESLVLGGGAPRYVREEKRPTYLDEVVKFDPNKIP
DLKPDTVPQTLNSLLSSLNISSRRPLYEQYDTEVGLVKVVEPGEDGGLVR
IPGTKKGIAVATDCNSRYTYLNPYEGAQIAVCESARNVAATGAEPYGVTN
NLNFGNPYIPENYYVFSECVRGLGDACRFLGLPVTGGNVSFYNESPEGPV
FPTPTIGMVGVIDDVAKGLRTYPRTKEDVKYALVGNFQPTISASEYLYRS
QGLDTGAIPNISLEKEKQTMDALIECRKNGLLTSAKDLSLGGLLVALAKI
VIAGKKGVEVNLNELQTKVPRLDALCFGETGASFIVSFLPNDETKVRESF
TSKGLSVYTLGSSSAKASLSVKGDGFHWEWTTKSLEVEFESGLKSYFE
>LEPBI_I0914 purM, Phosphoribosylaminoimidazole synthetase
MSDQNKITYKDAGVDTEKGQEFVKRIKANVASTHNKNVLGGLGGFAACYD
VSFLKSYQEPILLSGTDGVGTKLQIARQLGIHNTVGIDLVAMCVNDILVN
GGKPIFFQDYIACGKLHLPTMEAIVSGIVKGCSLADCSLVGGETAEHPGV
MPDDEYDLAGFVVGVVEKGKMIDGKTISPGDTIIGLKSSGPHSNGFSLIR
KLLLKDGKLPTSQEQIDFIKDHIFVPTNIYVKSILSLIDKISIKGMVHIT
GGGFYENIPRVLPEGVGAEIFSLPESYVFSKLEKDHSLDRNDMYGTFNMG
IGYILVVDSSLVDATMNELHVLGEDSFVIGKTNDSGKISITL
>LEPBI_I1470 purN, Phosphoribosylglycinamide formyltransferase
MGKTKRVVFLASGRGSNFSAAVESIQKKKLKLDILALVSDNPEAKALTIA
KNFGISTKVIPYGSYQSKSDYHRDLLRQVEAYDPDLIVACGYMRILKPEF
VQRFKNQIINVHPSLLPAFPGLDSQKQALDYGVKVAGCTVHFVWEGVDTG
PIILQKAIAIRPEWTEKELSLAILKEEHIILPLAIQLFCEDKLKIKERKV
EILK
>LEPBI_I1923 purQ, Phosphoribosylformylglycinamidine synthase I (FGAM synthase I)
MKVRVVTFPGSNCDKDVGSVLQESFQAEVIYTWYKESFEDVPDLVVLPGG
FSFGDYLRCGAMAKFSPSMESVVKYANKGGKVLGVCNGFQILTESGLLPG
ALLHNRTLKYICKDVELVPVKENSFAKKMEGTLSIPIAHGEGAYFADPET
LERLEKNGQVVFRYRENPNGSLHDIAGICNERGNVLGMMPHPERAMNPYT
GKMDGKQILEALLKN
>LEPBI_I1924 purS, Phosphorybosylformylglycinamidine synthase PurS component
MFVAKINVTLKESVLDPQGQTVLRTLHDQGKLQIQDLRVGKYIEIKLNAS
SQKEAEEIAKGICESVLVNQVIETYKLVVESQ
>LEPBI_I2735 purT, phosphoribosylglycinamide formyltransferase 2
MIGTPFTKHATKLLLLGSGELGKEVAIEANRLGVHVIAVDRYPNAPAMLV
AQESRVINMLDPKELEATIRELKPDFVVPEIEAIHTETLVTLEKDGFKII
PSAKAVNLTMNREGIRNFVANELGLITSQFLFADTIEDFTNAVHTIGFPC
VVKPIMSSSGKGQSLVKTEADIIKAWEYGQTGGRTGKGKMIIEEFIPFDF
EITLLTIRHIDGTSFLPPIGHRQVNGDYVESWMPQPMSDLALTSAKNIAE
TVTTGLGGFGIFGVELFVKGDEVYFSEVSPRPHDTGLVTLISQNVSEFSL
HVRALLGLPIPELIFQTPAASSAILLEGNTKSPEYVGLKEALAIKGVDIR
IFGKPEVEGKRRMGVSLALGNTIEEAKEKANRGRDHIQLKT
>LEPBI_I1026 pyrB, Aspartate carbamoyltransferase, catalytic subunit (Aspartate transcarbamylase; ATCase)
MYAYSHKNILDTLQFSKDDLNYLITKTNRMNALHESGKAFGILHGKLLAS
LFFEASTRTRMSFEAAMERLGGRLISTVGFQFSSISKGETLYDTMKMIEA
YCDIAVIRHPVEGSSRIAAGAVNIPVINAGDGAGQHPTQALLDLYTIVSE
KGKIDGLNIAFIGDLKYGRTIHSLINLLRHYPVHLYLISPEELRLPEKYK
KNLEGFPMTWEETTDIKAIWDADVAYVTRIQEERFPDHREYEKLKDIYKV
NKELVLASKKDTTILHPLPRVNELSTDVDDLPNAAYFRQAKYGVVVRMAL
LCLSLGVNFD
>LEPBI_I0308 pyrC, Dihydroorotase (Carbamoylaspartic dehydras; DHOase)
METIAGKIVTHEKEFLGSIEFDPTTGLITKVKEGIEPKSRQFSEDCVIFP
GFGDIHIHAREDVTGKHTYKEDFLSASAAAINGGVIHVADMPNNPVPPID
DATYAAKQALTEKAPIHITLYAGIGPHTKPLSKKVPYKVFMGPSIGELFF
HDNPSLEEVIQHYEGQDVSFHCEDPEILIANKDQPTHETRRPKEAETVAT
DFALYLIEKYNLKGKLCHYSTKDGLSKIIAAKKRGVKVTCEVTPTHLMFD
TDMLTETNHKWFQMNPPLRGRADREAMVKGILDGHIDYLATDHAPHSIEE
KQKGTSGISQLDTYGLFVTYMILNLNIPMTLIAKICSKNPGEFVAPYLPK
QFGKGVGVINEGYAANFSILNLKKPVEFKKSMIKSKSGWSPFEGFQFPGS
IEAVYYLGKEIHAK
>LEPBI_I0092 pyrD, Dihydroorotate dehydrogenase (Dihydroorotate oxydase)
MFYHQLIKPILFHLDPESAHHLVATFLSLSKKIPFFHKTLSAIFQFSSKR
LEQTIQGIHFPNPVGLAAGFDKTTELFPTMIHMGFGFIEIGTITAKAQPG
NEKPRLFRYPKVKALINRMGFNNPGADQAEINLKNQQKLGVRGINAGKSK
VTALEDAVGDYVYTLKKLVPFGDYAVINISSPNTPGLRSLQTKQSLIDLI
QGIQKEFQNSFPIPLYLKFAPDLTEEELIENLKVCLEYKISGVILTNTTL
DKQSLGELNPEEGGLSGGPLFQKSLRFVSLAYQTLQGKIPIIGVGGIDSG
EKALQMMEMGANLIQIYTGYIYEGPFLPYQICSYLDKVVKDRGYQTISEL
VGSGNSK
>LEPBI_I2428 pyrE, Orotate phosphoribosyltransferase (OPRT; OPRTase)
MSHSHRDALFQWMKTYVYRHSETPFRLASGLESQHYFNCKEITLHPERLS
ILAECFIEEIIPKLNIEFQAVGGLTLGADPIAYAISLGYQKRGKNVFPLV
VRKESKGHGTGQQIEGFWKDIKTCLVVDDVITTGGSTLKAVKVLREVGIN
VTKGICILDREEGGSENLQTENVTMTSIFAKSEFF
>LEPBI_II0110 pyrF, Orotidine-5'-monophosphate decarboxylase
MTSFLSKFRNRRDGLRSQLCIGIDPELEKLPKVCLDSKSPLVHFSETIVR
YTHPYAVAWKPNIAFFERLGAEGYFALEHMVHLMKEVSPEVPIVMDAKRG
DLANTAKEYAKYFFQTLKVDALTVNPYMGRDSLTPYLDLGGYLFVLGLTS
NPSSSDFQKLKTKTNDLYLYEEVSDQMASLSEVYPGQVGLVVGGTHPSEI
QSLRKRHPDLCFLIPGFGAQGGDLESIIHASGKEALINSSRGITLSSLAE
NYGEVSKKKSEEVHLRMNHLFP
>LEPBI_I1645 pyrG, CTP synthase (UTP--ammonia ligase; CTP synthetase)
MSKTRYIFITGGVSSSLGKGVTVAALGCLLEARGYTVSLQKMDPYINIDP
GTMSPYQHGEVYVTEDGAETDLDLGYYERFTKSKFSRKNSVSTGQIYHAV
IERERKGDYLGRTVQVVPHITNEIRSRIYNLTRDQETDFVIVEIGGTVGD
IESIPFLEAIRQMRYEHGNQQVLFLHLTLVPTITAAGEAKTKPTQHSVKE
LLALGIQPDVLICRINKPMSKEMKNKISLFCNVKEQNVISAVDITTSIYE
IPLMYREDKLDEVVLNALGMDLRKLNFSQWENMVKKIRNTKKTVKVALIG
KYISLQDAYRSVYESLAHGGIANDVEVSVVKINPEDIDSKNIKELLKGVH
GVLVPGGFGERGIEGKIAAIQYARTKNIPFFGICLGMQCAVIEFARNVLG
FKDANSTEFKPNVQYPVISMIEEQKEIERMGGTMRLGAYPCLVKKGSLAH
SEYKSDRISERHRHRFEFTLRYKDDFEKKGMNLTGFSPDGSLAEIVEIPN
HPWFIGVQFHPEFQSKPTDPHPLFAGFIKAASKLAKKTED
>LEPBI_I2615 pyrH, Uridylate kinase
MGTSPRFKRILIKISGEALAGEGELGIDTNKTFSLAGQIKEVHDLGLEVA
VVVGGGNMIRGETLAKSGMDRATADYMGMLGTIMNGLALQDACEKQGMFT
RVLSAIEMKSVAEPYIRRRAVRHLEKNRVIIFAGGTGNPYFTTDTTASLR
AVEVGCEVILKATKVDGVYTADPKKDPSAKRYLQVSFMESIKHRLKVMDS
TALSLCMDNNMPIIVFDIFKAGNLRKLIDGEPIGTLISNSEEVILDGR
>LEPBI_I3300 thyX, Thymidylate synthase ThyX (TS; TSase)
MQQSDFESISRVSVPELDSILGKPFPILDDGFVRLVDYMGSDESIVQAAR
VSYGKGTKKVNEDRGLIRYLMRHRHSTPFEMCELKLHVRVPMDTWRQWIR
HRMANVNEYSTRYSVAIDSAQTTLPGEWRVQSVGNKQGSDGYLESSKGDH
LTKRETEFQKFANDIYNERLEMGVAREQARKDLPLATYTEAYWKIDLHNL
LHFLALRMDDHAQLEIRLFAKTIGEQIVQKWVPHTWEAFVDYRLSALHLT
KYDTEIIAALNVSGKEGAIKKAIQLGMLDDQGTTAKKSREREELEYKLSQ
LGFSIPW
>LEPBI_I1268 tmk, Thymidylate kinase (dTMP kinase)
MPFKSQFFVFEGIDGSGKTTVSKKVSEILSTKSISNLWHREPTDSIHGQK
IREFLQGKIKLTPDEQLKLFLLDREFSVNETILPTLKSDTCLVQDRYYFS
TAAYQGRDEEHAADILYMNEDKGFPEPNRVYFLDLSPEEALERRNTRGGN
KEAFDDEKEQTRIYQNYLAILPESTIFVDATADLEEVVNFCVEDILLSLS
LKT


# Leptospira borgpetersenii serovar Hardjo-bovis JB197, JB197

>LBJ_0379 Metal-dependent hydrolase
MEYELVNACIVTKDRWIPNGSVVVKDGLIASVNAGGPPPGKRIRLNLNGL
YVYPGLFNAHDHLLSTYLPKVAPSKPYLNWLPWDNDLKSSIVFSERQQLD
PEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFVEKMPVRILNQYALSHSI
CTYSLNWGDGPKEEYAKALKQNIPYVTRIAEGFDSESRDSLKNLHKLGCL
GEHTVLIHGIVLSESDIQLISEKKAHLVWCPEANQFLYERTVDIRDLLKH
GINVSLGTDSSICGSLNLLEEISTARKFYQTEYGEDLSTKTLFEMVTCNP
AKAFRVEKQLGSIEVGKIADIVVLTRNIEDPYANLCESDLSSVRLVLRDG
IPVYGDVSLESFFEESGVIVERVRVDNIERYLVASPGKLLESLVISLGYK
KDLAFFPVQKEFDNFG
>LBJ_0700 Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase domain
MKVAIVTFPGSNCDSDIFRVLRDQYEAEVDRVWHRDQLDKKYELVILPGG
FSYGDYLRSGAMAGFSLVMKSVKEHVNKGGKLFGICNGFQILTEAEFLPG
ALTRNKTLKYICKTVILKKGSSGNPVTASLDSRKELKIPIAHADGCYYAT
SDVIKQLEDEERILFRYFGENPNGSLQAIAGITSKNFKVAGMMPHPERAM
NPVIGEVDGKIVLDLILSA
>LBJ_0163 Conserved hypothetical protein
MIFISVALFPEAKPLIETLGLKILRDKTPFPIYQNEKYILIVSGTGKIFS
AMSVAFLLNEFKNSVTDSSWILNFGICGAPKKSSKIGESFLIHKIKDEGS
SRSVYPDILFKSPIPESVLLTVDKPVFRNEISELPNTLVDMEAFGFFQAS
RKFFSSDKIRIVKTISDHFTKLESEKEIGIPSTISLRIKEALPNILSILS
IPVSKGNEVELQQNETTAFLFIAEFLRLSETERIQLKDWMIGYKIRTGNS
SEQGLNILKNANGTLNLKEAGVKTREEGRKGLYALKQFYQS
>LBJ_2174 HIT family hydrolase
MNDHHCIFCKIIRKEIPSKIAFENEEILAFHDISPQAPTHIVFVPKKHIK
SLREIGNEDSSLLGNMLLRIRDTAKNLGFAEDGYRIVNNTGRNGGQTVFH
IHFHLLAERQLLWPPG
>LBJ_2686 Adenylosuccinate synthase
MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKY
VFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECDRLQKEGFPVYDKLLLS
DACHLLFPYHSQIDSARETTVSQEHKIGTTKKGIGICYADKMMRTGLRVG
DLLDNSYESRLKHLVDEKNRELDKLYGMPPVSYKDINDGLKFFLSKVRKS
IINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNPTTGGALI
GTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEEGEALRQKGGEFGAT
TGRPRRCGWFDAEMLKHSVRINGITSIALTKIDILSDYDRIPVAVGYKLN
GKTLDCFPSQGLEKLEIVYEEFPGWKTDISGISEFQKLPEKCKNYISALE
KWIGVKINLVSTGPDRKDTIQGDSF
>LBJ_0482 HIT family hydrolase
MEESNSTQWDAPRKNLFSIHKLDYVRGKRPDVDCILCGICRKNPEVPSLI
VAETDLTIVSVNLYPYNPGHLIVFPKRHILAYEELTREEVMEIHDGTVKA
VSILKNLWNVQGFNLGYNLGKNAGGSIPHIHEHIVPRFPNEAGFLDVLAN
SRIVIYEPYEMHKEWVRVWKEFS
>LBJ_4170 Phosphoribosyltransferase
MSIVKSKIRTIPDYPKPGILFRDITSLLLDPEGLALTIGTFVNRYQDKGI
TKVAGIEARGFLTGAPLAFQLGVGFIPIRKKGKLPAETVSEEYDLEYGKD
VIEIHKDAVQPGDKILLMDDLIATGGTMIAAVKLLKKLGAQIYEAGVIID
LPDLGGSKKLQEKLEVPVFAICEFEGH
>LBJ_0213 Hypothetical protein
MNGPDSLEKRIERTETLISILSKEFFLKLKSDSEEWPRTYEFTHLEKNYK
AMFSVFGSFTLSDLKQTVGFSPIYYLSLCNNGYQQLVWTKPDGEIMDDPK
QIFDELKKYIQIFETSISKTHLREKQA
>LBJ_2920 Purine-nucleoside phosphorylase
MSRNVKAAIIGGTGLYSLDGMELIEEIYPDTPWGKPSDKIKIGKYKEKLI
AFLPRHGIGHFLSPPEIPNHANICALKQLGVEEIVAFSSVGSLREEIKPL
DFVLPSQIIDRTHLRDSTYFGNGIVAHAPFAEPFSQNLGKRIEQTAEKIG
LKIHTGKTLICMEGPLFSTKAESHLYRSWGADIINMTVLPEAKLAREAEI
SYQMICMSTDYDCWREGEESVTVEMVIANLTKNAETAKKLLSELIHVIGN
GDDLSLKNSTRYSIITAPEKRNPETVKKLKVLFPEYF
>LBJ_0412 Adenosine deaminase
MKQYADLHNHLYGSITSEFLYEIGRSNPSPRWEIFTNSYQQYFGKKISTE
TFFEDYKDPDSFRKLYLFNHCGPFPEFQAKFNLIIALSKFDPVEIALVAT
RVVEDQFRQGVTYGEYRVMYSPLETEQGIYDKTLAACEGLARGEEKTGGF
AKGKLVISLHRNGDVFREYSIYKDLMEKNPLIRDYLVGLDFCYIEEGFPP
KEKKDFFETVGEDNRAEKDTALAILYHVGESFQDKSILSASRWVLESAEW
GVHRLGHAIALGLDPFEKMKDKIKESKSERLDQLRLYYDRKEELDSYFEV
PSREKIGNEIDSLKHKEIVELETASSFLEECIGFQNYCIFKIKQTDAVIE
SCPSSNEFIGMVVDPKSHPILRFAKNGMKFTISTDDPGIFGTTIEAEYSK
AAQIGLSAEILETVRQNSFLFTSEILSGRKSAP
>LBJ_2999 Cytosine/adenosine deaminase
MYESLNDRILSDFFKSMKDLLLKEREEVPSFTRIYQKEELISETFNEVEK
HLDSSFHSEILCIRDAKKKLKTRYLTDCTLITSLEPCLMCTGTILLSRIP
KIIYLLPARQGEGISSLSIEMIYSRNFFPELICIPAEISKNAFKSFFKIR
RKKFN
>LBJ_1346 HIT family hydrolase
MSECPLCKFHQSGDLSEVLMRFGEFSVRQCEEEKKLKGYLYIEPRSHWTS
YQDWTKDSFSDFGKALEFATKWIYKNHVPIKVYTVTVSEAVPHMHFHLIP
RYSDDLKGIDYIRLALQGKLSEQSYIQNL
>LBJ_2875 Xanthosine triphosphate pyrophosphatase
MKRIVLATNNRHKVKEVGFILSELGIQVLTPNDLRISFNAEETGSTFAEN
AFIKARELFRLTKLPSIADDSGICVSALGGEPGVYSARFGGPGLKDEDRA
LFLLEKMKENSDRRAHYTCVIAYVDETSEQSFEGRCEGTISEEYDRIGMY
GFGYDPIFIYPPFQKPFSQVPEAEKNSVSHRKKALEQFLKFLKTKS
>LBJ_1795 Thymidylate synthase
MSAQKPIVSLLDHSKDPFNLSIATARTCYSSKGILLPSDMVASEKSIEIR
DKVAKSTKKAGHLTTRQHPQFIFTLDKVSRQFVWSFLHSHPFYNSEQVSQ
RYVEVKKENYYVPPELNGKLLELYLDAVDFASQAYFSYTEILHPFIQEEY
FRIYKARANYPDKWQIPIKKKCLEVARYLLPLGTYTYLYHSINGLTLHRY
YRLMNSYDVPQEQRAVVTEMVDQVRAVDPLYADEMDDPIPLEETTEYRYF
DSVFGSGKREFHPKVSANFVKEFDQELGTRYSRLVSYSSNGPEILAQSVR
SILGIPKSSLGDQDAIDLVLNPTKNGHLTSTLNENSMSPISRALFNVQYS
FQKRISHTADSQDQRHRMVPGGRPVLMSQYAGVPDYITPFVVQKYPELKE
KYDATHTRVFEKLNRFLDAGGSPEYGTYLLPNSFPIRFYESGDLLNLHHK
WRSRTCYNAQEEIFQASVEELTDVMKVHPGIAKWIKAPCWIRLQGEVKPY
CPEGDHYCGTQVWKRELSEYSRVI
>LBJ_2850 Cyclic amidohydrolase
MINKISGRIITHEKDFLGTVEWDSKTGLILGIREYTEAKTFWNTRPKEDE
IRFDPSETVIFPGFGDIHIHAREDESGKHIYKEDFISASAAAVNGGVIHV
ADMPNNPIPPVDEPTYSKKRKLADRSNIHITLYAGIGPNTKPLKQSVPYK
VFMGPSIGELFFHDNQTLEDTIRAYAGENVSFHCEDPEILEKYQNEKFHE
DRRPPEAETTATDFALYLIEKYDLRGKLCHYSTGKGLSKIKLAKQKGLKI
TCEVTPTHLFFDRSMLTSQNRHWFQMNPPLRDREDRKRMLEGVKQGWIDY
LATDHAPHSIEEKHKGTSGISQLDTYSLFVTWLILKAGVELKTIARICAK
NPGDFVNEYLPGRFGKGFGEIEPGYSANFTILNLKKPKKFLKEEIKSKSG
WSPFENYEFPGSIEAVFFCGVKMK
>LBJ_0617 add, Adenosine deaminase
MALTFGEILDRIRIIDRDVTELSRLKSRLPADRPYSSSLQISFDKQINEL
LNERVGLMELEIIDPPSWILGVPQETPVPIKGLFPSGDLSKEKPDDQDVI
NFLRELPKTEIHLHLEACVNKDTMKRLMAKNGISVTDEEFEAKFNFKDLN
GFIQVFFFIQSLVKEPADFSFFVGSLSEYMRANNIVYTEVFFAPSKFIQN
GLDFEEMVNFLVNRIREEKENDGITIRLLVDVSRSFGPENAMNNLNRVLK
LRHPEVIGIGLGGAELMGPARDYQAVFQKAREAGLRVVAHSGEDDGPWAI
WEAVELLKAERIGHGTSAIQDPELVKYLRENHIPIEICVTSNVFTGKYVR
KEQNHPIRYYYDQGLPLSINTDDPEIFNVNLTYEYYKLWRFLDFSLDEIV
DLIRQGVFASFHPNKESLWSEMEKKIHLVKARYGLKQ
>LBJ_2638 adk, Adenylate kinase
MKNIIFMGPPGAGKGTQAKILCARLSIPQISTGDILREAVKNQTPMGIEA
KRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQADALDAL
LKNEGKSIDKAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYN
KKTLPLLDFYAAQKKLSQVNGVGTLEEVTSLIQRELV
>LBJ_2602 adpP, ADP-ribose pyrophosphatase
MKYCSSCGSSVVYKIPEGDNRSRYVCDNCGTIHYQNPKIVVGSIPVWENR
ILLCKRAIEPRKGYWTLPAGFLENRETVEEGAVRETQEEANAEIRIVGLQ
SIYSIPHISQIYMFFLADLVDGRFSVSLESEEVKLFSMDEIPWEELAFSS
VHFALREYVDSPVKNSLHLGNTRNRKNFSKES
>LBJ_2119 carA, Carbamoyl-phosphate synthase (glutamine- hydrolyzing), small subunit
MKAFLVLDNGMILEGESFGYESESVGEIVFNTSMAGYQEILTDPSYCNQI
ITLTYPMIGNYGIHPDNMESSKIQASGLIVREYVDLPSNFMSQKTLSKFL
KEYQIPAIQGIDTRKLTRYIRTNGSPNGGIFVAREYSPEFLEKVKSFPGI
TGTDLAKVVTTSTKYIFGTHTGKKYKLAVYDYGVKTNILRLLDAAGFAVT
VYPALTPAEEIMKEGTDAFFLSNGPGDPAPLDYAIDATRKIMEKGYPLFG
ICLGHQIIGLSLGKKTEKMKFGHRGGNQPVKNLSTGQVEITSQNHGFAVI
DDGKSSEPVSFLNLNDNTVEGILKSGYPLLTVQYHPESAPGPNDSRYLFQ
KFYDLVETTKRGK
>LBJ_0774 carB, Carbamoyl-phosphate synthase (glutamine- hydrolyzing), large subunit
MPRREDIRSVLILGSGPIVIGQACEFDYSGTQAAKALKEKGIRVILLNSN
PATIMTDPDLADATYVEPMTVPVVQKILEKEKPDAILPTVGGQTALNLAL
ACNGAGLLEKYNVELIGAKVDAIKKAEDRELFKKAMEKIGVRVPASGLAN
NLTDAAEIKKKLGLPLIVRPAFTLGGTGGGIAYTEETFEEVVSKGLKASP
ISQVLLEESVLGWKEFELEVMRDLADNVVIICSIENIDPMGVHTGDSITV
APQQTLSDKEYQNLRDMSIAIIREIGVETGGSNIQFAVNPANEDVIVIEM
NPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIKNDITRVTPASFEPS
IDYVVTKVPRFAFEKFPGTDDTLGVQMKAVGEAMAIGRTFKESFQKALRS
LEIDRYGFGSDGYFQELLYTRSLNSDQRKEWIDSFLKRPNDKRIFYVKLA
FDEGYTVEQIHDLCKMDRWFLWQMEDLLKLEREYSEKGDSVLAKMKRAGF
SNRQLSFLKNKKRILDLLDGDLRVDLKKTEIQNILKKSEEEIETELGSEK
ILPVYKRIDTCAGEFEAYTPYFYSSYDEEDESDVTSTKSVMILGGGPNRI
GQGIEFDYCCCQASYALQDLGVESIMVNSNPETVSTDYDTSDRLYFEPLT
LEDVYRIYQNEKPEGVIIQFGGQTPLKLAKDLERKGVKILGTSPDSIDRA
EDRKRFVEVLEKLKLRSPESGIATSMEEAREIAQNVKYPILVRPSYVLGG
RAMLIINEEKELDRYMEKAEEISKDRPLLIDSFLEDAVEVDVDALCDGKE
VFVTGIMEHIEEAGIHSGDSACILPPQTLSKNMMDEIRKATVDLALELQV
KGLINIQYAVKNEILYVIEVNPRASRTVPFVSKALGHPIVKYATRVIMGE
SLKNLPLPKEMAFSQVSVKEVVLPFNKFPGVDTILGPEMRSTGEVMGIAS
TVGEAFLKSQYMAGDELPSQGTVFVSINDKTKLELLSYIKDLSELGFNLI
ATSGTHKFLSDNGILSSKINKVYDGIFPTALDYIRENKIHLIINTPLSRV
TRDDSFTIRQAAIRFKVPCLTTSNAAKALIKGMVEMKNKGFTVHSLQEIH
TMPKVL
>LBJ_0935 cmk, Cytidylate kinase
MNENVIALDGPAGSGKSTVARQIAERIGFNYLDTGAFYRALTLYLFRLHG
NSPNTESFADWVKTSEAERSLSDIRILCEFSAGKENRIFLNGEEVSLAIR
TPEITREIKHIANRRIYRNFVNQELHSLAKLHKLIIDGRDIGTEVFPDAK
FKFYLTASSKVRAERRFLQLQEQGIEADRDEIEKEIILRDKSDMEREIAP
LYQANDAILIDTDILSKNSVISKILKILDR
>LBJ_0062 dcd, dCTP deaminase
MILTGKEIQKRIGKDIIITPYSEKQLNPNSYNLRLHEELLIYTELPLDMK
KPNLTKKQIIPESGLLLKPGILYLGRTLEFTETHHLVPMLEGRSSIGRLG
MLVHVTAGFGDVGFKGFWTLEISVIQPLIVYPGVEVCQIFYHTLEGQITE
YTSGKYQANQGIQPSMLYQDFEK
>LBJ_1337 dgt, Deoxyguanosinetriphosphate triphosphohydrolase
MYFSRNDLIQKEIAGLAPYAISSTNNGGRFYEEEEHSYRLPFQRDRDRVL
HSSAFKRLQYKTQVFIFSVGENYRNRMTHTLEVAGLSRTIASALGLNSHL
SESIALAHDLGHTPFGHAGQEILSSLMKDHGGFEHNKQSLRIVTSIEKKY
PNFPGLNLCRETLKGLMKHGTEYDPSMMLLERKESGPSLEGMIADLSDEI
AYTSHDIEDGWEMGYLHLGDLSENPFWKEVYEECKEQYKDVGEKILVRTA
IRTLTNSMVSDLIQNISLQLETNQVKSTEDLIRLWKQGIRIASFSERVDS
KFRELKFFLYEKLYRHEDLVRMSDYGKKVIESLFDYFLKHPEKIPDTYKE
RIEEESLYRVISDYVAGMTDRYAEKIYQSLH
>LBJ_2235 dut, dUTP diphosphatase
MKIPIKKLRSNAELPVLQTKHAAGYDVHACLDSNLILEPNKVTLVPTGLS
FEIPQEYHFEIRPRSGFSTKNQILIPNSPGTIDSDYRGELMIPLFNLGNI
PFVIEHGMRIAQLLIRETHYTNWELVSEFTDTTERGTGGFGSTGH
>LBJ_1615 gmk, Guanylate kinase
MNSPKLFVLSSVAGGGKSTLIQKLREKHPDILFSISCTTRAPRPGDKEGV
TYFFLTREEFKKGIKDSMFLEWALVHDQYYGTPLKFIEEAFQKGSSVIMD
IDVQGAKIIKEKFPGRIVTIFILPPSEKEWERRLRHRGTDSEESILKRIR
NGKSELERQNEFDYKIVNDDLNQALADLERIILSKP
>LBJ_1742 gppA, Guanosine-5'-triphosphate, 3'-diphosphatepyrophosphatase
MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENG
PIDSDSFRRGIDCLKRFKILAENAGAEIRAVATSALREASNREEFLEVVY
QETGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGH
RGNILFSKSFKLGAIRLTEKFFQEEPLSNSGIRKCRLFIEEMLLPFRKIL
RDLKPDLVVGSSGTIQAIAGMILASRGESEEISLNNFSFLTSEFKKIRNL
ILEADTSRKRTKIPGLDSKRADIIIGGTLILEEIFDLANVPALTVSEFAL
REGIVYDTIRKWEHFESREHSKHLDAIRQTSVDNFMRAFSRDEEYSKHVA
NLSLQIFDQLASLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI
RNSEMLLGFTFLEIEIIALTARYHRKNIPKLKHREFNKLAEKNRNLVCQL
SAILRISSALNRNRGGLVPSVTCKTEKNQIRFVLHTNKGYDPSLEIWAAE
EQKIAFEETFGYSVEFVTGNVR
>LBJ_1553 guaA-1, Glutamine amidotransferase
MRSLIVRFKDCEGPGILLDSLKERNYKITYHNAYDSRVRPFPDAHLVFDL
VVLLGGPQSVTDPTLVPFFEPWLNLVRYTASMPNRKVIGICLGAQIISKA
LGGEVRRGEKGPEVGFYDVQVQEPTHLVFDGITSFPAFHLHEDIFSIPQR
AKHLLKSEMYSNQMFSFQDRIFGIQCHMEVTASMLKVWRVVHSDFIRSWV
PGPDTEILRSQMENVGRRVFAAILDLTPDSTVDRSAFIPQSPDFVAAENG
>LBJ_1923 guaA-2, GMP synthase (glutamine-hydrolyzing)
MEVRKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPLSNYQKYTGII
LSGGPESVYEPDSPTITTRIFELGIPVLGICYGHQLIMKLLGGVVKRSGT
GEYGPTSLQIHDSGENFLLKNFIGGERVWMNHADEVVKLPEGFTRTASSK
DCGYAVVENTSKKIFGIQFHAEVSHSENGSLLLDNFIQICGASRTWGIDR
FLKKKIEEIQKTVKPEQKIFMLVSGGVDSTVSYLLLCKALGAERVFGFLV
DTGFMRKGEVLYLQERLALQDIRLTVRDESNLFYESLKGKSDPEEKRKIV
GNLFLEVRDRAIKDLDLEHGDWLLGQGTIYPDTIESGGTKHSHTIKTHHN
RVEAIQKLIEEGKIIEPIRDLYKDEVRDLGVLLGLEAEWVGRHPFPGPGL
VVRMLAVEKKGTSEDQKEIDSYLATQGGLSGKILPVASVGVKGDRRSYAN
CVVLSDIGTNWKTLDRVATHLSNQFSFINRVVLLPFETDVKKLNFQFTGM
QLDKNYSDLLREADYAVESVIRKAGLYDKIWQMPVVLLPIGEKKNEKSIV
LRPVESQEAMTANFFPMERFLLQEIKDVVSKISGIRYVFFDLTNKPPGTI
EWE
>LBJ_2933 hpt, Hypoxanthine phosphoribosyltransferase
MNEIDSNTLRPCFNREEISQKVKFLASEITKDYKKLNPILICVLKGGMYF
FADLTRAIPFSVEIDFIQARSYSGTSSTGNIDLLKDIDTDLSNRHVILVE
DILDTGFTLQYLIRHIFARNPASLEIVTLLLKKRKSILEFPVKYVGWRIS
DEFVVGYGMDFDGKYRNLPDIHVLETG
>LBJ_1530 imdH, Inosine-5'-monophosphate dehydrogenase
MSNQTYRDSEYLDGLSGDELFSLQIGLTYRDFLVLPGFIDFHPSEVELET
RLTRNIRLKRPFISSPMDTVTESQMAIAQALMGGIGIIHYNNTIEEQVAL
VEKVKRFENGFITDPVVLGPKNIIRDLDRIKEHKGFTGIPVTEDGTRNSK
LIGIVTNRDIDFERNREITLDEVMTKNVITGKEGITLQDANDIIKKSKIG
KLPIVDSDGKLVSLVSRSDLKKNKEFPDASKDEGKRLRCGAAVSTLLESR
DRVAALYEAGVDVIIIDSAQGNSNYQIEMIQFIKKEFKNLDIVAGNVVTR
AQAENLIRAGADGLRIGMGPGSICITQDTMAVGRAQATAVYQTAKHAAKY
DVPVIADGGISNIGDIANSLAIGASTCMMGFMFAGTTEAPGEYFYENGIR
LKKYRGMASIEAMKAGGDKRYFNEGQKVKVAQGVSGSVVDRGSILNFIPY
LSQGLRLSFQDMGYKSIPEIHKALREGKLRFERRSESAQAQGSVHGLYSF
SAPTMRAE
>LBJ_2883 ndk, Nucleoside-diphosphate kinase
MSKTFIMIKPDGVKNKHVGNILARIEKEGFKILGLKYLKLSLEDAKQFYK
VHSARPFYSDLCNYMSSGPIVAAALERDNAVLHWREVIGATDPKEAAAGT
IRALYAESKEANAVHGSDSDENAALEVSFFFKGNELF
>LBJ_1270 nrdA, Ribonucleoside-triphosphate reductase, alpha subunit
MKINRHFTAPRNGESPTIRWAKRNSKITNPDGSKVFEANDILVPEDWSQV
AVDILAQKYFRRKGVPKYLKKVQEDGIPEWLQKSVPDTEKLESLKPEDRF
GGETSALQVFHRLAGCWTYWGYKYKYFSDEESAKVFYDEIVSMLGTQMAA
PNSPQWFNTGLNWAYGIDGKSQGHYYVDPTTGKLVKSTSAYEHPQPHACF
IQSVDDDLVNDGGIMDLWVREARLFKYGSGTGTNFSHLRGENEPLSGGGK
SSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIESFIDWKVTE
EKKVASLVTGSILNNRHLNAIMSACYEMEGEDRFDPKKNPSLKKNILEAK
KVLIPDNYIKRVIDLAKQGYKEILFEELTTDWQSDAYNTVSGQNSNNSVR
LTNEFMAAVEQDQPWNLYFRTEKEKAKFEGRKAKPSQTLRARELWEKISY
AAWASADPGTQYHTTINEWHTCPEDGSINASNPCSEYMFLDNTACNLASA
NLQKFVNLETLNFDVEGFRYLCRLWTIILEISVTMAQFPSKEIAELSYKF
RTLGLGYANLGSVLMILGIPYDSQEAMAITGAISSIMHMTAYATSAEMAK
EQGPFTGYAKNKKHMLRVIRNHRRAAYNAPSRDYENLTITPIGINPAFCP
SYLLKAAQEDADFALELGEKHGFRNAQVTVIAPTGTIGLVMDCDTTGIEP
DFALVKFKKLAGGGYFKIINQSVPYGLKKLGYSTSEIEAIVNYCKGHATL
NGAPIINTQTLKEKGFTNEILEKVEASLPLAFDINFAFNKFNLGENFLIK
DLGITKEVFNAPGFSLLEHIGFTKEEINKANDYVCGTMTIENAPFLKEKD
YPVFDCANKCGKYGKRFLSYESHIHIMAAAQPFISGAISKTINLPEEATI
EDIKDAYFLSWKMMIKANALYRDGSKLSQPLNSVLELLNGIEVDDRDEIR
EAMLSKDPVQIAEKVITKYISHRRKLPSRRAGYTQKAIVGGHKVYLRTGE
YEDGQIGEIFIDMHKEGAAFRSLMNAFAISVSLGLQHGVPLEEYVDAFTF
FKFEPNGIVSGNKHIKMSTSVIDYIFRELAITYLGRYDLGQVAPEDLRGD
EIGSKRATAESNSQETINFTTITTESVPKKEVETISYSQMISKERATTSL
ALLEEIKLAKIKGYTGDSCSECGSFEMVRNGSCLKCMSCGATTGCS
>LBJ_2587 prsA, Ribose-phosphate diphosphokinase
MNGDIAVFAGSSNKQIAEEICTHLNIQPGKINLKKFSDGEISVKVEDNVR
GREVFIVQSTSAPANDHLMELILIMDAFRRASVSSISVVIPYYGYGRQDR
KVEPRVPISARIVADLLEVVGLDRILTMDLHADQIQGFFRVPVDNLHFAP
VLAEYVNTKNINDLVIVSPDSGGAERARAFGKKVNGSLAIIDKRRPKANV
SEVMNVIGEIEGKNCILLDDMIDTAGTICKAADALLKHGAKSVYCAATHG
VLSGESVDRINATNFTEVVLANTIAIPESKKIHKLKSLSVAPLFANAIKR
IHTNQSVSTLFD
>LBJ_0845 purB, Adenylosuccinate lyase
MIDRYSNPEISKIWELENKFEIWKEIEILACEIRMKRGEIPPEEFQEIKT
MAKFNVGEILEIESKVHHDVIAFLTNMNSYIGPAGRHVHYGLTSSDIGDT
ALCVQMVQAMDLILKKTDALISVVKEKAIQYRDLPCIGRSHGIHAEPMTL
GLKFALFFEELNRNRKRMSEARNEIAVGKLSGAVGTYSNVDPEIEAYVCE
KMGLKVDPISTQVVSRDRHAFYLSVLGVTASSLDRMATEIRLLQKTEGRE
VEEPFSAGQKGSSAMPHKRNPVICERISGLSRVIRANVNVGLQDVALWHE
RDISHSSAERVVLPDSTIALEYILDKMLFVVKNLHVYPDAIERTLGVTRG
LIFSQKVLLALIERGKIAREEAYLIVQEHAMAVWANPSETLKTRLENDNR
IGQVLTRKDLEDIFKIEPYLEKVGLIYRRLGLE
>LBJ_0698 purC, Phosphoribosylaminoimidazole-succinocarboxamidesynthase
MNLPTYRGKVRDIYDLGDRLILSSSDRISAFDVVFPQAVPNKGKVLNRIS
ISWFEFFKNIPNHILETDVKNFPSPFRSREELEGRSVLVKKCKRIDYECV
VRGYIAGSGWKEYKNEGTLAGVKLPAGLKESEKLPEPVFTPAVKNDQGHD
ENISEKEMENRVGKELFGILKEKSISIFLRASEVVDSAGIILCDTKFEFG
ILDGQIILIDELLTPDSSRYWSADSYSVGISPPSLDKQILRNYLETTSWN
KMPPAPDLPAELIQELREKYQKIEDLILSCISQKSK
>LBJ_0530 purD, Phosphoribosylamine--glycine ligase
MQVKLKVLLIGSGGRESAIAFHLRKSSLLSELKVFPGNGGFPDNEILPSD
SFNILSKESVQSFLKLNPFDFIVVGPEDPLVAGFADWAAELEIPTFGPDS
YCAQVEGSKNFAKSLMVEANIPTAVYKTFTEYSASLNYLESQTVPIVIKA
DGLAAGKGVTVATTKKMAMNALKEIFKDKKFGESGNQVVIEEFMEGQEAS
IFAVSDGDSYFLLPAAQDHKRAFDGDQGPNTGGMGAYCPAPVITETILQK
VKEKIFDRMFETFRKKGHPYRGLLYAGLMISPDGEPKVVEFNCRFGDPET
QCVLAMFDGDLLELLYIASTGKIKEVRTSIKSGAATVVVLAAQGYPDSYE
KNIPLNLPETSGQNVYLFHAGTSKKDGKVFSSGGRILGVVAQGTDLRNSV
DQAYSFLEKIQVPKTFYRKDIGHKAL
>LBJ_0962 purE, Phosphoribosylaminoimidazole carboxylase, catalytic subunit
MSAKVAIIMGSHSDWETMRETESILKEFGVSFHKEIVSAHRSPEHMLEFS
KSAKQNGYSVIIAGAGGAAHLPGMVASMTTLPVLGVPIQSKTLNGLDSLL
SIVQMPGGVPVGTLAIGTAGAKNAALLAIRILSLQDSELSEKLEQYRNQI
REDALSKNKDLL
>LBJ_0194 purF, Amidophosphoribosyltransferase
MSRIPDKSRVRRQAQDDKPKDECAIFGIFNSSEASNFTYLGLYSMQHRGQ
ESSGIVSSDGEHLYRYAGMGLVASIFTEAKLKELQGASAIGHNRYSTTGA
SFLRNAQPLRVESHLGAVSLAHNGNLVNSWELRSQLEKEGSIFQTTIDSE
VIVHLMARSGETDFLSALSSALKKVRGAYSLVILTKTQLIAVRDPNGFRP
LVMGRREDGSIVFASETCAFDITDTKYERDVGPGEMVVVDKNGVNSYYPF
PKATPSLCIFEYIYFARPDSSIFGESVYKVRKNLGRFLARELPVEADVVI
PVPDSANIAALGYAEESGISYQSGLIRSHYIGRTFIEPDQKIRDFGAKIK
YNVVRNVVEGKRVIVVDDSIMRGTTSRKIIKMVRNAGAKEVHLRVSAPPT
ISPCYYGIDIPTHNELIAATHTIEEIRKYLRVDTISYLSVESMNRAVMDH
KGGGFCNACFTAQYPVEFQSELGNQKSLFKEYQVEERAVY
>LBJ_1329 purH, Bifunctional purine biosynthesis protein
MIQIKRALISVSDKSDIVEFAQFLNQNGVEIISTGGTLKLLKDNGIQAIA
IDDYTGFPEILEGRVKTLHPKVHGGLLGVVSNPAHKQKMEELKIPKIDLV
VVNLYPFLKTVSKPGVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPS
DYEEVRVLIASGGISEEVAAGYMRKAFSHTAMYDTAISSWFHKQAGDVFP
DVLNLSFLKKQKLRYGENPHQAASFYEPLFVKSDFSPLQGKELSFNNMLD
FDAAFHISSLLPENTVCIIKHLNPCGIAYADDPLEAFQLARRTDPISAFG
GVIGIKGIVHGELATAITENFVEGVIAQKFTPEALELFSKKPNIRLIEIE
NFKEALDELDLRPIHHGLLIQERDYTTITEKDLKVVTKKQPTSDDIRGLM
FAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGANKALNVGLSV
VGSYVASDAFFPFRDGIDALAKAGAKAIIQPGGSVRDAEVIQAADEHGLI
MVFTGMRHFRH
>LBJ_0961 purK, Phosphoribosylaminoimidazole carboxylase, ATPase subunit
MKNNDVLTPGSKLGVMGAGQLARMFCLEAIPFGYEVSVYSPEKNPAAAGV
GAKPYLSAYEDEEALVAFLKNIDALTFEFENIPEIALSTIDKFSKQTGLK
VHPSPNCIQIAQNRWKEKNSFREAGIPTVNFYPIFTEKDKLSVLSNVKFP
CILKTNTMGYDGKGQIQCKTKKELSSALSSLKELNHIVEELFPFTAEASV
ILARFENGKILNFRPSRNVHKNHILDLTFYPGNFSEKIETELINHSKKLA
EKIDYVGVFGIEFFIKNEEVLCNEFAPRPHNSGHFSQNSGTLSQFSLQLR
TLCNLPSPNTIPTKPITMKNILGEDYKPNSPLWNSALENPYYHLHLYGKN
EVRNGRKMGHWNYSGPNPESAFSDWN
>LBJ_2272 purL, Phosphoribosylformylglycinamidine synthase
MEKDVVSLQDALEHGLTAEEFQKIQEILGRIPNSTELGIFSAMWSEHCSY
KNSVLKLKTLPTSSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAV
EPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPRNKYLLSRAVK
GIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGIVRHDQMASATTGG
QVGNAVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLL
MEASLEAIQKGLLIGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRE
TGMNAYEVMLSESQERMLVVPKKGKESELVSIFEKWNLNAVRIGEVTADG
FIEIYMGGKLKAHIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPNSIL
DITPGANTKDVLLNILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLS
SIPDTNKALATATDCNSRYTYLDPYKGAQFAVCEAARNVYVTGATPYGVT
NNLNFANPYIPENYYMFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGP
IFPTPTIGMVGILQDKKKFLSNFPKEVGIELAVLGNFRPSLGGSEYLKKI
HGQVNGSIPEIDIKEELELCKLILSLNEKGALKSARDLSLGGIGIALSKT
ILFSGLGIDAELIAFKQSRLDLTLFGESSTTVLVGFDSSWKEKIREQTEE
KGLKFYPVGKTTSSELLKLKDIGVEVSFSELNGPYEKGLEVVFAL
>LBJ_2290 purM, Phosphoribosylformylglycinamidine cyclo-ligase
MEEKITYKSVGVDTEKGREFVQKIKRNVESTHGPRVLGGLGGFAGAYDVS
ILKKYNQPVLLSGTDGVGTKIELARLLNTFDTIGIDLVAMCVNDILVCGG
EPLFFLDYIVCGKLDIEKMDRIVAGIVHGCKLSNTALLGGETAEHPGTMK
EDEFDLAGFVVGVVERDLMIDGSMIRPGDKILGLESSGPHSNGFSLIRKL
LLKDGKHLPSDPEQIKFLKDYALKPTRIYVQSILKLLQKVPVKGMVHITG
GGYQENVPRVLPKGSQAKFYKDKIPSGYFFEKIKRDYKLDELELFGTFNM
GIGYMLVVSKEHVDIAEEFLESTGESVHKIGEIVSGNREEIQLV
>LBJ_1330 purN, Phosphoribosylglycinamide formyltransferase
MASPFTKPKKKIVFLTSGRGSNLKAVLQRIKVGKIRGVGSALICDNPDAK
ALEVAQEFKLPSHVFNFASFVDKSEYHKKLLNFLIELEPDLIVTAGYMKI
LKNQVIQAFPNRIINIHPSLLPAFPGLNAQKQAFEYGVKIAGCTAHFVDE
GVDSGPVILQGVVKIEEGMSERDLTLEILKEEHKILPLAVQYFCEDRLKI
HNRKVSIE
>LBJ_0699 purS, Phosphoribosylformylglycinamidine synthase
MYIAKIQVVLKESVLDPQGSTVKKVLSEVGEKSVQDVRVGKYIELKIDAP
NEETARKDVERLCDKILVNHVIETYSANIQKI
>LBJ_2952 purT, Phosphoribosylglycinamide formyltransferase
MKKKILLLGSGELGKEFIIAAQRLGQYVIAVDFYDGAPAMQVAHEKEIIN
MLDGNLLDQVVKKHKPDLIVPEIEAIRTERFYEYEKQGYQIVPSAKAANF
TMNRKSIRDLAAKDLKLLTAKYLYASSEKELAKATKILGFPCVVKPLMSS
SGKGQSIIKSPKDISKAWEASQTKGRTSATEIIVEEFISFKSEITLLTVT
QKNGKTLFCPPIGHRQERGDYQESWQPAEISEVQLKEAQRMAEAVTKELT
GFGIWGVEFFLTEDQVYFSELSPRPHDTGMVTLSGTQNFNEFELHIRAIL
GIPIPEVTQERKGASAVILASTDGKIPEVRGLDIASEMPESDFRIFGKPI
TRPYRRMGIALSYSTKGEGISSLRKRAILLASKIKVD
>LBJ_0731 pyrB, Aspartate carbamoyltransferase, catalytic chain
MSYNHKNVLDTEQFSKSDLDFLIKKIKDMEHLVERHKAFGILTGKLLASL
FFEASTRTRLSFEAAMERLGGRVISTVGFQFSSISKGETLYDTMKMVEAY
ADIAVIRHPVEGSSRIAAGAVKIPVVNAGDGAGQHPTQAILDLYTIISEK
GTLDGLSVAFIGDLKYGRTIHSLINLLRHYKVRLYLISPIELALPDSYKK
GLEGYPLTLEETTDIKAVWECDVAYVTRIQEERFPDHKEYERLKDLFKIN
KELILASKKETTILHPLPRVNELSTDVDDLPNAAYFRQARYGVVSRMTLL
CLCLGQDF
>LBJ_2928 pyrD, Dihydroorotate dehydrogenase
MIDTDSIVLEMFSSTLKQAAYSTFLKPFFLSLDPETSHELAKNLLSISAK
FPGILTLVESMTSYRSDRLKTRVAGIEFENPLGMGAGFDKTGELYPFLSR
MGFGHIEIGTITGKSQPGNLKPRVFRYPEDQALINRMGFNNPGADSAERI
IAPQKKRKIRGINAGKTKIISEEKAVEDYIYTLKKLSPYADYAVINISSP
NTPGLRDFQKQKNFVSLIQGIKNGLGKNFIIPLFVKFAPDMETKDIEALL
ESSLSLKIDGVVLTNTTIDKSSLKAYPNVEKEGGLSGVPLKNRSTEFVRV
AYRILKRRIPIIGVGGIDSEKAALEKILAGADLIQIYTGYIYQGPFLPLK
ILEFLDRFLKEQDLKTVSDLVGKEKEIQYDPKCS
>LBJ_2101 pyrE, Orotate phosphoribosyltransferase
MKQKLLELILTHAYRYSEQPFTLASGKKSRHYFNCKEITLVPDRLELLCK
FIVERHLDESGILKPQAFGGLTMGADPICYGISLEFRKQDKNIYPLIVRK
FSKDHGTNKLVEGAVHEVKSCVIVDDVITTGGSTIQAIRSMRDSGIVVVQ
GICILDRQEGGMDAILAEGVQMFPIFKKSDFGNLEHE
>LBJ_4227 pyrF, Orotidine-5'-phosphate decarboxylase
MNFQSKFLTRSQSLKSLLCVGLDPDYCKLPEIIKRSPEPLVHFCREIIDA
TAPYAVAYKPNIAFFEVFGSSGIRQFEKVIGHLKNNYPQIPIVADIKRGD
LDNTARQYARYYFGDLQVDSLTLSPYMGLDTLRPFLEYQDHLVFWLCLTS
SPDSIQFQKKRFSETGRTLYEEVAYVANSISPLNLGFVVGATNTYELEIL
RKQNPDRIFLIPGFGAQGAKLDDLLPVCGRYSLINSSRGIHFASDGLDFA
ARANQEAEKIHNAMQARFVFL
>LBJ_1451 pyrG, CTP synthase
MSRTKFIFVTGGVSSSLGKGVTVAALGCLLESRGYTVSLQKMDPYINIDP
GTMSPYQHGEVYVTADGAETDLDLGYYERFTHSKLSRKNSVSTGQIYNTV
IQRERKGDYLGRTVQVVPHITNEIRNRMYIVAREENPDFIIVEIGGTVGD
IESIPFLEAIRQIRYEHGSSNVLFVHLTLVPTITAAGEAKTKPTQHSVKE
LLGLGIQPDILVCRVSQPMTKEMKNKLSLFCNVKEENVISASDISTSIYE
IPKMYKEEKLDEVVLKTMGMELRESNFSEWDKMIRRLLATKQTVQVAIVG
KYISLQDAYRSIYESLSHGGIAYDTKVEFVKIDPENLNKDNVQSSLKNVH
GVLVPGGFGDRGIEGKILAIEYARTNGIPFFGICLGMQCAVVEYGRNVLK
LKDANSTEIRPDTEYPVISLLEEQNDIEQMGATMRLGSYPCKIKKDTLSY
SEYKSTLVHERHRHRFEFTNRYRKQYEENGMVISGTSPDDSLVEIVEIPK
HNWFVGVQFHPEFQSRPTKPHPLFAGFIRAAVKYSKKGSS
>LBJ_0906 pyrH, Uridylate kinase
MGSKYKRILIKLSGEALAGEGEFGIDTNKAHSLAEEIKEVHDLGVEIALV
VGGGNIIRGTNLAKVGIDRATADYMGMLATIQNALALQDACEKKGLYTRV
QSAIEINSIAESYIRRRAVRHLEKRRIVIFAGGTGNPYFTTDTTASLRAV
EVGCDVILKATKVDGVYTADPKKDNGAKRYSQISFMESINRRLKVMDSTA
LSLCMENNMPIIVFDIFKQGNLKDLVTGKNIGTLISNSEDIQIDGK
>LBJ_0758 tmk, Thymidylate kinase
MKIEKPIFVVFEGIDGSGKSTLCKSLTEKLTERGIPSVNFTEPTNFETGK
YLRKFLRGEIDLERKEQIDAFLNDREESLRQNILPSLESGKNVLLDRYMY
STAAYQSGDDLLPETIIEKNLKKNFKIPDLLFYLDLNPAIALERLSQRKE
NKERFETLAQLEKIRSAYNRILPKETIRIDGVKGPDEIVQECLEIFLRNF
NKKFL


# Leptospira borgpetersenii serovar Hardjo-bovis L550, L550

>LBL_0387 Adenylosuccinate synthase
MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKY
VFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECDRLQKEGFPVYDKLLLS
DACHLLFPYHSQIDSARETTVSQEHKIGTTKKGIGICYADKMMRTGLRVG
DLLDNSYESRLKHLVDEKNRELDKLYGMPPVSYKDINDGLKFFLSKVRKS
IINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNPTTGGALI
GTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEEGEALRQKGGEFGAT
TGRPRRCGWFDAEMLKHSVRINGITSIALTKIDILSDYDRIPVAVGYKLN
GKTLDCFPSQGLEKLEIVYEEFPGWKTDISGISEFQKLPEKCKNYISALE
KWIGVKINLVSTGPDRKDTIQGDSF
>LBL_0062 Cytosine/adenosine deaminase
MYESLNDRILSDFFKSMKDLLLKEREEVPSFTRIYQKEELISETFNEVEK
HLDSSFHSEILCIRDAKKKLKTRYLTDCTLITSLEPCLMCTGTILLSRIP
KIIYLLPARQGEGISSLSIEMIYSRNFFPELICIPAEISKNAFKSFFKIR
RKKFN
>LBL_2597 HIT family hydrolase
MEESNSTQWDAPRKNLFSIHKLDYVRGKRPDVDCILCGICRKNPEVPSLI
VAETDLTIVSVNLYPYNPGHLIVFPKRHILAYEELTREEVMEIHDGTVKA
VSILKNLWNVQGFNLGYNLGKNAGGSIPHIHEHIVPRFPNEAGFLDVLAN
SRIVIYEPYEMHKEWVRVWKEFS
>LBL_4185 Phosphoribosyltransferase
MSIVKSKIRTIPDYPKPGILFRDITSLLLDPEGLALTIGTFVNRYQDKGI
TKVAGIEARGFLTGAPLAFQLGVGFIPIRKKGKLPAETVSEEYDLEYGKD
VIEIHKDAVQPGDKILLMDDLIATGGTMIAAVKLLKKLGAQIYEAGVIID
LPDLGGSKKLQEKLEVPVFAICEFEGH
>LBL_2168 HIT family hydrolase
MNDHHCIFCKIIRKEIPSKIAFENEEILAFHDISPQAPTHIVFVPKKHIK
SLREIGNEDSSLLGNMLLRIRDTAKNLGFAEDGYRIVNNTGRNGGQTVFH
IHFHLLAERQLLWPPG
>LBL_2379 Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase domain
MKVAIVTFPGSNCDSDIFRVLRDQYEAEVDRVWHRDQLDKKYELVILPGG
FSYGDYLRSGAMAGFSPVMKSVKEHVNKGGKLFGICNGFQILTEAEFLPG
ALTRNKTLKYICKTVILKKGSSGNPVTASLDSRKELKIPIAHADGCYYAT
SDVIKQLEDEERILFRYFGENPNGSLQAIAGITSKNFKVAGMMPHPERAM
NPVIGEVDGKIVLDLILSA
>LBL_0143 Purine-nucleoside phosphorylase
MSRNVKAAIIGGTGLYSLDGMELIEEIYPDTPWGKPSDKIKIGKYKEKLI
AFLPRHGIGHFLSPPEIPNHANICALKQLGVEEIVAFSSVGSLREEIKPL
DFVLPSQIIDRTHLRDSTYFGNGIVAHAPFAEPFSQNLGKRIEQTAEKIG
LKIHTGKTLICMEGPLFSTKAESHLYRSWGADIINMTVLPEAKLAREAEI
SYQMICMSTDYDCWREGEESVTVEMVIANLTKNAETAKKLLSELIHVIGN
GDDLSLKNSTRYSIITAPEKRNPETVKKLKVLFPEYF
>LBL_1571 HIT family hydrolase
MSECPLCKFHQSGDLSEVLMRFGEFSVRQCEEEKKLKGYLYIEPRSHWTS
YQDWTKDSFSDFGKALEFATKWIYKNHVPIKVYTVTVSEAVPHMHFHLIP
RYSDDLKGIDYIRLALQGKLSEQSYIQNL
>LBL_2920 Conserved hypothetical protein
MIFISVALFPEAKPLIETLGLKILRDKTPFPIYQNEKYILIVSGTGKIFS
AMSVAFLLNEFKNSVTDSSWILNFGICGAPKKSSKIGESFLIHKIKDEGS
SRSVYPDILFKSPIPESVLLTVDKPVFRNEISELPNTLVDMEAFGFFQAS
RKFFSSDKIRIVKTISDHFTKLESEKEIGIPSTISLRIKEALPNILSILS
IPVSKGNEVELQQNETTAFLFIAEFLRLSETERIQLKDWMIGYKIRTGNS
SEQGLNILKNANGTLNLKEAGVKTREEGRKGLYALKQFYQS
>LBL_2665 Adenosine deaminase
MKQYADLHNHLYGSITSEFLYEIGRSNPSPRWEIFTNSYQQYFGKKISTE
TFFEDYKDPDSFRKLYLFNHCGPFPEFQAKFNLIIALSKFDPVEIALVAT
RVVEDQFRQGVTYGEYRVMYSPLETEQGIYDKTLAACEGLARGEEKTGGF
AKGKLVISLHRNGDVFREYSIYKDLMEKNPLIRDYLVGLDFCYIEEGFPP
KEKKDFFETVGEDNRAEKDTALAILYHVGESFQDKSILSASRWVLESAEW
GVHRLGHAIALGLDPFEKMKDKIKESKSERLDQLRLYYDRKEELDSYFEV
PSREKIGNEIDSLKHKEIVELETASSFLEECIGFQNYCIFKIKQTDAVIE
SCPSSNEFIGMVVDPKSHPILRFAKNGMKFTISTDDPGIFGTTIEAEYSK
AAQIGLSAEILETVRQNSFLFTSEILSGRKSAP
>LBL_1079 Thymidylate synthase
MSAQKPIVSLLDHSKDPFNLSIATARTCYSSKGILLPSDMVASEKSIEIR
DKVAKSTKKAGHLTTRQHPQFIFTLDKVSRQFVWSFLHSHPFYNSEQVSQ
RYVEVKKENYYVPPELNGKLLELYLDAVDFASQAYFSYTEILHPFIQEEY
FRIYKARANYPDKWQIPIKKKCLEVARYLLPLGTYTYLYHSINGLTLHRY
YRLMNSYDVPQEQRAVVTEMVDQVRAVDPLYADEMDDPIPLEETTEYRYF
DSVFGSGKREFHPKVSANFVKEFDQELGTRYSRLVSYSSNGPEILAQSVR
SILGIPKSSLGDQDAIDLVLNPTKNGHLTSTLNENSMSPISRALFNVQYS
FQKRISHTADSQDQRHRMVPGGRPVLMSQYAGVPDYITPFVVQKYPELKE
KYDATHTRVFEKLNRFLDAGGSPEYGTYLLPNSFPIRFYESGDLLNLHHK
WRSRTCYNAQEEIFQASVEELTDVMKVHPGIAKWIKAPCWIRLQGEVKPY
CPEGDHYCGTQVWKRELSEYSRVI
>LBL_2698 Metal-dependent hydrolase
MEYELVNACIVTKDRWIPNGSVVVKDGLIASVNAGGPPPGKRIRLNLNGL
YVYPGLFNAHDHLLSTYLPKVAPSKPYLNWLPWDNDLKSSIVFSERQQLD
PEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFVEKMPVRILNQYALSHSI
CTYSLNWGDGPKEEYAKALKQNIPYVTRIAEGFDSESRDSLKNLHKLGCL
GEHTVLIHGIVLSESDIQLISEKKAHLVWCPEANQFLYERTVDIRDLLKH
GINVSLGTDSSICGSLNLLEEISTARKFYQTEYGEDLSTKTLFEMVTCNP
AKAFRVEKQLGSIEVGKIADIVVLTRNIEDPYANLCESDLSSVRLVLRDG
IPVYGDVSLESFFEESGVIVERVRVDNIERYLVASPGKLLESLVISLGYK
KDLAFFPVQKEFDNFG
>LBL_0196 Xanthosine triphosphate pyrophosphatase
MKRIVLATNNRYKVKEVGFILSELGIQVLTPNDLRISFNAEETGSTFAEN
AFIKARELFRLTKLPSIADDSGICVSALGGEPGVYSARFGGPGLKDEDRA
LFLLEKMKENSDRRAHYTCVITYVDETSEQSFEGRCEGTISEEYDRIGMY
GFGYDPIFIYPPFQKPFSQVPEAEKNSVSHRKKALEQFLKFLKTKS
>LBL_2869 Hypothetical protein
MNGPDSLEKRIERTETLISILSKEFFLKLKSDSEEWPRTYEFTHLEKNYK
AMFSVFGSFTLSDLKQTVGFSPIYYLSLCNNGYQQLVWTKPDGEIMDDPK
QIFDELKKYIQIFETSISKTHLREKQA
>LBL_0221 Cyclic amidohydrolase
MINKISGRIITHEKDFLGTVEWDSKTGLILGIREYTEAKTFWNTRPKEDE
IRFDPSETVIFPGFGDIHIHAREDESGKHIYKEDFISASAAAVNGGVIHV
ADMPNNPIPPVDEPTYSKKRKLADRSNIHITLYAGIGPNTKPLKQSVPYK
VFMGPSIGELFFHDNQTLEDTIRAYAGENVSFHCEDPEILEKYQNEKFHE
DRRPPEAETTATDFALYLIEKYDLRGKLCHYSTGKGLSKIKLAKQKGLKI
TCEVTPTHLFFDRSMLTSQNRHWFQMNPPLRDREDRKRMLEGVKQGWIDY
LATDHAPHSIEEKHKGTSGISQLDTYSLFVTWLILKAGVELKTIARICAK
NPGDFVNEYLPGRFGKGFGEIEPGYSANFTILNLKKPKKFLKEEIKSKSG
WSPFENYEFPGSIEAVFFCGVKMK
>LBL_2462 add, Adenosine deaminase
MALTFGEILDRIRIIDRDVTELSRLKSRLPADRPYSSSLQISFDKQINEL
LNERVGLMELEIIDPPSWILGVPQETPVPIKGLFPSGDLSKEKPDDQDVI
NFLRELPKTEIHLHLEACVNKDTMKRLMAKNGISVTDEEFEAKFNFKDLN
GFIQVFFFIQSLVKEPADFSFFVGSLSEYMRANNIVYTEVFFAPSKFIQN
GLDFEEMVNFLVNRIREEKENDGITIRLLVDVSRSFGPENAMNNLNRVLK
LRHPEVIGIGLGGAELMGPARDYQAVFQKAREAGLRVVAHSGEDDGPWAI
WEAVELLKAERIGHGTSAIQDPELVKYLRENHIPIEICVTSNVFTGKYVR
KEQNHPIRYYYDQGLPLSINTDDPEIFNVNLTYEYYKLWRFLDFSLDEIV
DLIRQGVFASFHPNKESLWSEMEKKIHLVKARYGLKQ
>LBL_0474 adk, Adenylate kinase
MKNIIFMGPPGAGKGTQAKILCARLSIPQISTGDILREAVKNQTPMGIEA
KRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQADALDAL
LKNEGKSIDKAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYN
KKTLPLLDFYAAQKKLSQVNGVGTLEEVTSLIQRELV
>LBL_0434 adk-1, Adenylate kinase
MKNIIFMGPPGAGKGTQAKILCARLSIPQISTGDILREAVKNQTPMGIEA
KRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQADALDAL
LKNEGKSIDKAINLEVPDGELLKRLLGRAEIEGRADDNEATIKNRLDNYN
KKTLPLLDFYAAQKKLSQVNGVGTLEEVTSLIQRELV
>LBL_0510 adpP, ADP-ribose pyrophosphatase
MKYCSSCGSSVVYKIPEGDNRSRYVCDNCGTIHYQNPKIVVGSIPVWENR
ILLCKRAIEPRKGYWTLPAGFLENRETVEEGAVRETQEEANAEIRIVGLQ
SIYSIPHISQIYMFFLADLVDGRFSVSLESEEVKLFSMDEIPWEELAFSS
VHFALREYVDSPVKNSLHLGNTRNRKNFSKES
>LBL_2116 carA, Carbamoyl-phosphate synthase (glutamine- hydrolyzing), small subunit
MKAFLVLDNGMILEGESFGYESESVGEIVFNTSMAGYQEILTDPSYCNQI
ITLTYPMIGNYGIHPDNMESSKIQASGLIVREYVDLPSNFMSQKTLSKFL
KEYQIPAIQGIDTRKLTRYIRTNGSPNGGIFVAREYSPEFLEKVKSFPGI
TGTDLAKVVTTSTKYIFGTHTGKKYKLAVYDYGVKTNILRLLDAAGFAVT
VYPALTPAEEIMKEGTDAFFLSNGPGDPAPLDYAIDATRKIMEKGYPLFG
ICLGHQIIGLSLGKKTEKMKFGHRGGNQPVKNLSTGQVEITSQNHGFAVI
DDGKSSEPVSFLNLNDNTVEGILKSGYPLLTVQYHPESAPGPNDSRYLFQ
KFYDLVETTKRGK
>LBL_2304 carB, Carbamoyl-phosphate synthase (glutamine- hydrolyzing), large subunit
MPRREDIRSVLILGSGPIVIGQACEFDYSGTQAAKALKEKGIRVILLNSN
PATIMTDPDLADATYVEPMTVPVVQKILEKEKPDAILPTVGGQTALNLAL
ACNGAGLLEKYNVELIGAKVDAIKKAEDRELFKKAMEKIGVRVPASGLAN
NLTDAAEIKKKLGLPLIVRPAFTLGGTGGGIAYTEETFEEVVSKGLKASP
ISQVLLEESVLGWKEFELEVMRDLADNVVIICSIENIDPMGVHTGDSITV
APQQTLSDKEYQNLRDMSIAIIREIGVETGGSNIQFAVNPANGDVIVIEM
NPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIKNDITRVTPASFEPS
IDYVVTKVPRFAFEKFPGTDDTLGVQMKAVGEAMAIGRTFKESFQKALRS
LEIDRYGFGSDGYFQELLYTRSLNSDQRKEWIDSFLKRPNDKRIFYVKLA
FDEGYTVEQIHDLCKMDRWFLWQMEDLLKLEREYSEKGDSVLAKMKRAGF
SNRQLSFLKNKKRILDLLDGDLRVDLKKTEIQNILKKSEEEIETELGSEK
ILPVYKRIDTCAGEFEAYTPYFYSSYDEEDESDVTSTKSVMILGGGPNRI
GQGIEFDYCCCQASYALQDLGVESIMVNSNPETVSTDYDTSDRLYFEPLT
LEDVYRIYQNEKPEGVIIQFGGQTPLKLAKDLERKGVKILGTSPDSIDRA
EDRKRFVEVLEKLKLRSPESGIATSMEEAREIAQNVKYPILVRPSYVLGG
RAMLIINEEKELDRYMEKAEEISKDRPLLIDSFLEDAVEVDVDALCDGKE
VFVTGIMEHIEEAGIHSGDSACILPPQTLSKNMMDEIRKATVDLALELQV
KGLINIQYAVKNEILYVIEVNPRASRTVPFVSKALGHPIVKYATRVIMGE
SLKNLPLPKEMAFSQVSVKEVVLPFNKFPGVDTILGPEMRSTGEVMGIAS
TVGEAFLKSQYMAGDELPSQGTVFVSINDKTKLELLSYIKDLSELGFNLI
ATSGTHKFLSDNGILSSKINKVYDGIFPTALDYIRENKIHLIINTPLSRV
TRDDSFTIRQAAIRFKVPCLTTSNAAKALIKGMVEMKNKGFTVHSLQEIH
AMPKVL
>LBL_2098 cmk, Cytidylate kinase
MNENVIALDGPAGSGKSTVARQIAERIGFNYLDTGAFYRALTLYLFRLHG
NSPNTESFADWVKTSEAERSLSDIRILCEFSAGKENRIFLNGEEVSLAIR
TPEITREIKHIAKRRIYRNFVNQELHSLAKLHKLIIDGRDIGTEVFPDAK
FKFYLTASSKVRAERRFLQLQEQGIEADRDEIEKEIILRDKSDMEREIAP
LYQANDAILIDTDILSKNSVISKILKILDR
>LBL_3016 dcd, dCTP deaminase
MILTGKEIQKRIGKDIIITPYSEKQLNPNSYNLRLHEELLIYTELPLDMK
KPNLTKKQIIPESGLLLKPGILYLGRTLEFTETHHLVPMLEGRSSIGRLG
MLVHVTAGFGDVGFKGFWTLEISVIQPLIVYPGVEVCQIFYHTLEGQITE
YTSGKYQANQGIQPSMLYQDFEK
>LBL_1562 dgt, Deoxyguanosinetriphosphate triphosphohydrolase
MYFSRNDLIQKEIAGLAPYAISSTNNGGRFYEEEEHSYRLPFQRDRDRVL
HSSAFKRLQYKTQVFIFSVGENYRNRMTHTLEVAGLSRTIASALGLNSHL
SESIALAHDLGHTPFGHAGQEILSSLMKDHGGFEHNKQSLRIVTSIEKKY
PNFPGLNLCRETLKGLMKHGTEYDPSMMLLERKESGPSLEGMIADLSDEI
AYTSHDIEDGWEMGYLHLGDLSENPFWKEVYEECKEQYKDVGEKILVRTA
IRTLTNSMVSDLIQNISLQLETNQVKSTEDLIRLWKQGIRIASFSERVDS
KFRELKFFLYEKLYRHEDLVRMSDYGKKVIESLFDYFLKHPEKIPDTYKE
RIEEESLYRVISDYVAGMTDRYAEKIYQSLH
>LBL_2228 dut, dUTP diphosphatase
MKIPIKKLRSNAELPVLQTKHAAGYDVHACLDSNLILEPNKVTLVPTGLS
FEIPQEYHFEIRPRSGFSTKNQILIPNSPGTIDSDYRGELMIPLFNLGNI
PFVIEHGMRIAQLLIRETHYTNWELVSEFTDTTERGTGGFGSTGH
>LBL_1833 gmk, Guanylate kinase
MNSPKLFVLSSVAGGGKSTLIQKLREKHPDILFSISCTTRAPRPGDKEGV
TYFFLTREEFKKGIKDSMFLEWALVHDQYYGTPLKFIEEAFQKGSSVIMD
IDVQGAKIIKEKFPGRIVTIFILPPSEKEWERRLRHRGTDSEESILKRIR
NGKSELERQNEFDYKIVNDDLNQALADLERIILSKP
>LBL_1961 gppA, Guanosine-5'-triphosphate, 3'-diphosphatepyrophosphatase
MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENG
PIDSDSFRRGIDCLKRFKILAENAGAEIRAVATSALREASNREEFLEVVY
QETGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGH
RGNILFSKSFKLGAIRLTEKFFQEEPLSNSGIRKCRLFIEEMLLPFRKIL
RDLKPDLVVGSSGTIQAIAGMILASRGESEEISLNNFSFLTSEFKKIRNL
ILEADTSRKRTKIPGLDSKRADIIIGGTLILEEIFDLANVPALTVSEFAL
REGIVYDTIRKWEHFESREHSKHLDAIRQTSVDNFMRAFSRDEEYSKHVA
NLSLQIFDQLASLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI
RNSEMLLGFTFLEIEIIALTARYHRKNIPKLKHREFNKLAEKNRNLVCQL
SAILRISSALNRNRGGLVPSVTCKTEKNQIRFVLHTNKGYDPSLEIWAAE
EQKIAFEETFGYSVEFVTGNVR
>LBL_1777 guaA-1, Glutamine amidotransferase
MRSLIVRFKDCEGPGILLDSLKERNYKITYHNAYDSRVRPFPDAHLVFDL
VVLLGGPQSVTDPTLVPFFEPWLNLVRYTASMPNRKVIGICLGAQIISKA
LGGEVRRGEKGPEVGFYDVQVQEPTHLVFDGITSFPAFHLHEDIFSIPQR
AKHLLKSEMYSNQMFSFQDRIFGIQCHMEVTASMLKVWRVVHSDFIRSWV
PGPDTEILRSQMENVGRRVFAAILDLTPDSTVDRSAFIPQSPDFVAAENG
>LBL_1361 guaA-2, GMP synthase (glutamine-hydrolyzing)
MEVRKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPLSNYQKYTGII
LSGGPESVYEPDSPTITTRIFELGIPVLGICYGHQLIMKLLGGVVKRSGT
GEYGPTSLQIHDSGENFLLKNFIGGERVWMNHADEVVKLPEGFTRTASSK
DCGYAVVENTSKKIFGIQFHAEVSHSENGSLLLDNFIQICGASRTWGIDR
FLKKKIEEIQKTVKPEQKIFMLVSGGVDSTVSYLLLCKALGAERVFGFLV
DTGFMRKGEVLYLQERLALQDIRLTVRDESNLFYESLKGKSDPEEKRKIV
GNLFLEVRDRAIKDLDLEHGDWLLGQGTIYPDTIESGGTKHSHTIKTHHN
RVEAIQKLIEEGKIIEPIRDLYKDEVRDLGVLLGLEAEWVGRHPFPGPGL
VVRMLAVEKKGTSEDQKEIDSYLATQGGLSGKILPVASVGVKGDRRSYAN
CVVLSDIGTNWKTLDRVATHLSNQFSFINRVVLLPFETDVKKLNFQFTGM
QLDKNYSDLLREADYAVESVIRKAGLYDKIWQMPVVLLPIGEKKNEKSIV
LRPVESQEAMTANFFPMERFLLQEIKDVVSKISGIRYVFFDLTNKPPGTI
EWE
>LBL_0130 hpt, Hypoxanthine phosphoribosyltransferase
MNEIDSNTLRPCFNREEISQKVKFLASEITKDYKKLNPILICVLKGGMYF
FADLTRAIPFSVEIDFIQARSYSGTSSTGNIDLLKDIDTDLSNRHVILVE
DILDTGFTLQYLIRHIFARNPASLEIVTLLLKKRKSILEFPVKYVGWRIS
DEFVVGYGMDFDGKYRNLPDIHVLETG
>LBL_1754 imdH, Inosine-5'-monophosphate dehydrogenase
MSNQTYRDSEYLDGLSGDELFSLQIGLTYRDFLVLPGFIDFHPSEVELET
RLTRNIRLKRPFISSPMDTVTESQMAIAQALMGGIGIIHYNNTIEEQVAL
VEKVKRFENGFITDPVVLGPKNIIRDLDRIKEHKGFTGIPVTEDGTRNSK
LIGIVTNRDIDFERNREITLDEVMTKNVITGKEGITLQDANDIIKKSKIG
KLPIVDSDGKLVSLVSRSDLKKNKEFPDASKDEGKRLRCGAAVSTLLESR
DRVAALYEAGVDVIIIDSAQGNSNYQIEMIQFIKKEFKNLDIVAGNVVTR
AQAENLIRAGADGLRIGMGPGSICITQDTMAVGRAQATAVYQTAKHAAKY
DVPVIADGGISNIGDIANSLAIGASTCMMGFMFAGTTEAPGEYFYENGIR
LKKYRGMASIEAMKAGGDKRYFNEGQKVKVAQGVSGSVVDRGSILNFIPY
LSQGLRLSFQDMGYKSIPEIHKALREGKLRFERRSESAQAQGSVHGLYSF
SAPTMRAE
>LBL_0180 ndk, Nucleoside-diphosphate kinase
MSKTFIMIKPDGVKNKHVGNILARIEKEGFKILGLKYLKLSLEDAKQFYK
VHSARPFYSDLCNYMSSGPIVAAALERDNAVLHWREVIGATDPKEAAAGT
IRALYAESKEANAVHGSDSDENAALEVSFFFKGNELF
>LBL_1495 nrdA, Ribonucleoside-triphosphate reductase, alpha subunit
MKINRHFTAPRNGESPTIRWAKRNSKITNPDGSKVFEANDILVPEDWSQV
AVDILAQKYFRRKGVPKYLKKVQEDGIPEWLQKSVPDTEKLESLKPEDRF
GGETSALQVFHRLAGCWTYWGYKYKYFSDEESAKVFYDEIVSMLGTQMAA
PNSPQWFNTGLNWAYGIDGKSQGHYYVDPTTGKLVKSTSAYEHPQPHACF
IQSVDDDLVNDGGIMDLWVREARLFKYGSGTGTNFSHLRGENEPLSGGGK
SSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIESFIDWKVTE
EKKVASLVTGSILNNRHLNAIMSACYEMEGEDRFDPKKNPSLKKNILEAK
KVLIPDNYIKRVIDLAKQGYKEILFEELTTDWQSDAYNTVSGQNSNNSVR
LTNEFMAAVEQDQPWNLYFRTEKEKAKFEGRKAKPSQTLRARELWEKISY
AAWASADPGTQYHTTINEWHTCPEDGSINASNPCSEYMFLDNTACNLASA
NLQKFVNLETLNFDVEGFRYLCRLWTIILEISVTMAQFPSKEIAELSYKF
RTLGLGYANLGSVLMILGIPYDSQEAMAITGAISSIMHMTAYATSAEMAK
EQGPFTGYAKNKKHMLRVIRNHRRAAYNAPSRDYENLTITPIGINPAFCP
SYLLKAAQEDADFALELGEKHGFRNAQVTVIAPTGTIGLVMDCDTTGIEP
DFALVKFKKLAGGGYFKIINQSVPYGLKKLGYSTSEIEAIVNYCKGHATL
NGAPIINTQTLKEKGFTNEILEKVEASLPLAFDINFAFNKFNLGENFLIK
DLGITKEVFNAPGFSLLEHLGFTKEEINKANDYVCGTMTIENAPFLKEKD
YPVFDCANKCGKYGKRFLSYESHIHIMAAAQPFISGAISKTINLPEEATI
EDIKDAYFLSWKMMIKANALYRDGSKLSQPLNSVLELLNGIEVDDRDEIR
EAMLSKDPVQIAEKVITKYISHRRKLPSRRAGYTQKAIVGGHKVYLRTGE
YEDGQIGEIFIDMHKEGAAFRSLMNAFAISVSLGLQHGVPLEEYVDAFTF
FKFEPNGIVSGNKHIKMSTSVIDYIFRELAITYLGRYDLGQVAPEDLRGD
EIGSKRATAESNSQETINFTTITTESVPKKEVETISYSQMISKERATTSL
ALLEEIKLAKIKGYTGDSCSECGSFEMVRNGSCLKCMSCGATTGCS
>LBL_0525 prsA, Ribose-phosphate diphosphokinase
MNGDIAVFAGSSNKQIAEEICTHLNIQPGKINLKKFSDGEISVKVEDNVR
GREVFIVQSTSAPANDHLMELILIMDAFRRASVSSISVVIPYYGYGRQDR
KVEPRVPISARIVADLLEVVGLDRILTMDLHADQIQGFFRVPVDNLHFAP
VLAEYVNTKNINDLVIVSPDSGGAERARAFGKKVNGSLAIIDKRRPKANV
SEVMNVIGEIEGKNCILLDDMIDTAGTICKAADALLKHGAKSVYCAATHG
VLSGESVDRINATNFTEVVLANTIAIPESKKIHKLKSLSVAPLFANAIKR
IHTNQSVSTLFD
>LBL_2237 purB, Adenylosuccinate lyase
MIDRYSNPEISKIWELENKFEIWKEIEILACEIRMKRGEIPPEEFQEIKT
MAKFNVGEILEIESKVHHDVIAFLTNMNSYIGPAGRHVHYGLTSSDIGDT
ALCVQMVQAMDLILKKTDALISVVKEKAIQYRDLPCIGRSHGIHAEPMTL
GLKFALFFEELNRNRKRMSEARNEIAVGKLSGAVGTYSNVDPEIEAYVCE
KMGLKVDPISTQVVSRDRHAFYLSVLGVTASSLDRMATEIRLLQKTEGRE
VEEPFSAGQKGSSAMPHKRNPVICERISGLSRVIRANVNVGLQDVALWHE
RDISHSSAERVVLPDSTIALEYILDKMLFVVKNLHVYPDAIERTLGVTRG
LIFSQKVLLALIERGKIAREEAYLIVQEHAMAVWANPSETLKTRLENDNR
VGQVLTRKDLEDIFKIEPYLEKVGLIYRRLGLE
>LBL_2381 purC, Phosphoribosylaminoimidazole-succinocarboxamidesynthase
MNLPTYRGKVRDIYDLGDRLILSSSDRISAFDVVFPQAVPNKGKVLNRIS
ISWFEFFKNIPNHILETDVKNFPSPFRSREELEGRSVLVKKCKRIDYECV
VRGYIAGSGWKEYKNEGTLAGVKLPAGLKESEKLPEPVFTPAVKNDQGHD
ENISEKEMENRVGKELFGILKEKSISIFLRASEVVDSAGIILCDTKFEFG
ILDGQIILIDELLTPDSSRYWSADSYSVGISPPSLDKQILRNYLETTSWN
KMPPAPDLPAELIQELREKYQKIEDLILSCISQKSK
>LBL_2549 purD, Phosphoribosylamine--glycine ligase
MQVKLKVLLIGSGGRESAIAFHLRKSSLLSELKVFPGNGGFPDNEILPSD
SFNILSKESVQSFLKLNPFDFIVVGPEDPLVAGFADWAAELEIPTFGPDS
YCAQVEGSKNFAKSLMVEANIPTAVYKTFTEYSASLNYLESQTVPIVIKA
DGLAAGKGVTVATTKKMAMNALKEIFKDKKFGESGNQVVIEEFMEGQEAS
IFAVSDGDSYFLLPAAQDHKRAFDGDQGPNTGGMGAYCPAPVITETILQK
VKEKIFDRMFETFRKKGHPYRGLLYAGLMISPDGEPKVVEFNCRFGDPET
QCVLAMFDGDLLELLYIASTGKIKEVRTSIKSGAATVVVLAAQGYPDSYE
KNIPLNLPETSGQNVYLFHAGTSKKDGKVFSSGGRILGVVAQGTDLRNSV
DQAYSFLEKIQVPKTFYRKDIGHKAL
>LBL_2071 purE, Phosphoribosylaminoimidazole carboxylase, catalytic subunit
MSAKVAIIMGSHSDWETMRETESILKEFGVSFHKEIVSAHRSPEHMLEFS
KSAKQNGYSVIIAGAGGAAHLPGMVASMTTLPVLGVPIQSKTLNGLDSLL
SIVQMPGGVPVGTLAIGTAGAKNAALLAIRILSLQDSELSEKLEQYRNQI
REDALSKNKDLL
>LBL_2889 purF, Amidophosphoribosyltransferase
MSRIPDKSRVRRQAQDDKPKDECAIFGIFNSSEASNFTYLGLYSMQHRGQ
ESSGIVSSDGEHLYRYAGMGLVASIFTEAKLKELQGASAIGHNRYSTTGA
SFLRNAQPLRVESHLGAVSLAHNGNLVNSWELRSQLEKEGSIFQTTIDSE
VIVHLMARSGETDFLSALSSALKKVRGAYSLVILTKTQLIAVRDPNGFRP
LVMGRREDGSIVFASETCAFDITDTKYERDVGPGEMVVVDKNGVNSYYPF
PKATPSLCIFEYIYFTRPDSSIFGESVYKVRKNLGRFLARELPVEADVVI
PVPDSANIAALGYAEESGISYQSGLIRSHYIGRTFIEPDQKIRDFGAKIK
YNVVRNVVEGKRVIVVDDSIMRGTTSRKIIKMVRNAGAKEVHLRVSAPPT
ISPCYYGIDIPTHNELIAATHTIEEIRKYLRVDTISYLSVESMNRAVMDH
KGGGFCNACFTAQYPVEFQSELGNQKSLFKEYQVEERAVY
>LBL_1554 purH, Bifunctional purine biosynthesis protein
MIQIKRALISVSDKSDIVEFAQFLNQNGVEIISTGGTLKLLKDNGIQAIA
IDDYTGFPEILEGRVKTLHPKVHGGLLGVVSNPAHKQKMEELKIPKIDLV
VVNLYPFLKTVSKPGVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPS
DYEEVRVLIASGGISEEVAAGYMRKAFSHTAMYDTAISSWFHKQAGDVFP
DVLNLSFLKKQKLRYGENPHQAASFYEPLFVKSDFSPLQGKELSFNNMLD
FDAAFHISSLLPENTVCIIKHLNPCGIAYADDPLEAFQLARRTDPISAFG
GVIGIKGIVHGELATAITENFVEGVIAQKFTPEALELFSKKPNIRLIEIE
NFKEALDELDLRPIHHGLLIQERDYTTITEKDLKVVTKKQPTSDDIRGLM
FAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGANKALNVGLSV
VGSYVASDAFFPFRDGIDALAKAGAKAIIQPGGSVRDAEVIQAADEHGLI
MVFTGMRHFRH
>LBL_2072 purK, Phosphoribosylaminoimidazole carboxylase, ATPase subunit
MKNNDVLTPGSKLGVMGAGQLARMFCLEAIPFGYEVSVYSPEKNPAAAGV
GAKPYLSAYEDEEALVAFLKNIDALTFEFENIPEIALSTIDKFSKQTGLK
VHPSPNCIRIAQNRWKEKNSFREAGIPTVNFYPIFTEKDKLSVLSNVKFP
CILKTNTMGYDGKGQIQCKTKKELSSALSSLKELNHIVEELFPFTAEASV
ILARFENGKILNFRPSRNVHKNHILDLTFYPGNFSEKIETELINHSKKLA
EKIDYVGVFGIEFFIKNEEVLCNEFAPRPHNSGHFSQNSGTLSQFSLQLR
TLCNLPSPNTIPTKPITMKNILGEDYKPNSPLWNSALENPYYHLHLYGKN
EVRNGRKMGHWNYSGPNPESAFSDWN
>LBL_0835 purL, Phosphoribosylformylglycinamidine synthase
MEKDVVSLQDALEHGLTAEEFQKIQEILGRIPNSTELGIFSAMWSEHCSY
KNSVLKLKTLPTSSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAV
EPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPRNKYLLSRAVK
GIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGIVRHDQMASATTGG
QVGNAVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLL
MEASLEAIQKGLLIGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRE
TGMNAYEVMLSESQERMLVVPKKGKESELVSIFEKWNLNAVRIGEVTADG
FIEIYMGGKLKAHIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPNSIL
DITPGANTKDVLLNILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLS
SIPDTNKALATATDCNSRYTYLDPYKGAQFAVCEAARNVYVTGATPYGVT
NNLNFANPYIPENYYMFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGP
IFPTPTIGMVGILQDKKKFLSNFPKEVGIELAVLGNFRPSLGGSEYLKKI
HGQVNGSIPEIDIKEELELCKLILSLNEKGALKSARDLSLGGIGIALSKT
ILFSGLGIDAELIAFKQSRLDLTLFGESSTTVLVGFDSSWKEKIREQTEE
KGLKFYPVGKTTSSELLKLKDIGVEVSFSELNGPYEKGLEVVFAL
>LBL_0817 purM, Phosphoribosylformylglycinamidine cyclo-ligase
MEEKITYKSVGVDTEKGREFVQKIKRNVESTHGPRVLGGLGGFAGAYDVS
ILKKYNQPVLLSGTDGVGTKIELARLLNTFDTIGIDLVAMCVNDILVCGG
EPLFFLDYIACGKLDIEKMDRIVAGIVHGCKLSNTALLGGETAEHPGTMK
EDEFDLAGFVVGVVERDLMIDGSMIRPGDKILGLESSGPHSNGFSLIRKL
LLKDGKHLPSDPEQIKFLKDYALKPTRIYVQSILKLLQKVPVKGMVHITG
GGYQENVPRVLPKGSQAKFYKDKIPSGYFFEKIKRDYKLDELELFGTFNM
GIGYMLVVSKEHVDIAEEFLESTGESVHKIGEIVSGNREEIQLV
>LBL_1555 purN, Phosphoribosylglycinamide formyltransferase
MASPFTKPKKKIVFLTSGRGSNLKAVLQRIKVGKIRGVGSALICDNPDAK
ALEVAQEFKLPSHVFNFASFVDKSEYHKKLLNFLIELEPDLIVTAGYMKI
LKNQVIQAFPNRIINIHPSLLPAFPGLNAQKQAFEYGVKIAGCTAHFVDE
GVDSGPVILQGVVKIEEGMSERDLTLEILKEEHKILPLAVQYFCEDRLKI
HNRKVSIE
>LBL_2380 purS, Phosphoribosylformylglycinamidine synthase
MYIAKIQVVLKESVLDPQGSTVKKVLSEVGEKSVQDVRVGKYIELKIDAP
NEETARKDVERLCDKILVNHVIETYSANIQKI
>LBL_0112 purT, Phosphoribosylglycinamide formyltransferase
MKKKILLLGSGELGKEFIIAAQRLGQYVIAVDFYDGAPAMQVAHEKEIIN
MLDGNLLDQVVKKHKPDLIVPEIEAIRTERFYEYEKQGYQIVPSAKAANF
TMNRKSIRDLAAKDLKLLTAKYLYASSEKELAKATKILGFPCVVKPLMSS
SGKGQSIIKSPKDISKAWEASQTKGRTSATEIIVEEFISFKSEITLLTVT
QKNGKTLFCPPIGHRQERGDYQESWQPAEISEVQLKEAQRMAEAVTKELT
GFGIWGVEFFLTEDQVYFSELSPRPHDTGMVTLSGTQNFNEFELHIRAIL
GIPIPEVTQERKGASAVILASTDGKIPEVRGLDIASEMPESDFRIFGKPI
TRPYRRMGIALSYSTKGEGISSLRKRAILLASKIKVD
>LBL_2345 pyrB, Aspartate carbamoyltransferase, catalytic chain
MSYNHKNVLDTEQFSKSDLDFLIKKIKDMEHLVERHKAFGILTGKLLASL
FFEASTRTRLSFEAAMERLGGRVISTVGFQFSSISKGETLYDTMKMVEAY
ADIAVIRHPVEGSSRIAAGAVKIPVVNAGDGAGQHPTQAILDLYTIISEK
GTLDGLSVAFIGDLKYGRTIHSLINLLRHYKVRLYLISPIELALPDSYKK
GLEGYPLTLEETTDIKAVWECDVAYVTRIQEERFPDHKEYERLKDLFKIN
KELILASKKETTILHPLPRVNELSTDVDDLPNAAYFRQARYGVVSRMTLL
CLCLGQDF
>LBL_0135 pyrD, Dihydroorotate dehydrogenase
MIDTDSIVLEMFSSTLKQAAYSTFLKPFFLSLDPETSHELAKNLLSISAK
FPGILTLVESMTSYRSDRLKTRVAGIEFENPLGMGAGFDKTGELYPFLSR
MGFGHIEIGTITGKSQPGNLKPRVFRYPEDQALINHMGFNNPGADSAERI
IAPQKKRKIRGINAGKTKIISEEKAVEDYIYTLKKLSPYADYAVINISSP
NTPGLRDFQKQKNFVSLIQGIKNGLGKNFIIPLFVKFAPDMETKDLEALL
ESSLSLKIDGVVLTNTTIDKSSLKAYPNVEKEGGLSGVPLKNRSTEFVRV
AYRILKRRIPIIGVGGIDSEKAALEKILAGADLIQIYTGYIYQGPFLPLK
ILEFLDRFLKEQDLKTVSDLVGKEKEIQYDPKCS
>LBL_0950 pyrE, Orotate phosphoribosyltransferase
MKQKLLELILTHAYRYSEQPFTLASGKKSRHYFNCKEITLVPDRLELLCK
FIVERHLDESGILKPQAFGGLTMGADPICYGISLEFRKQDKNIYPLIVRK
FSKDHGTNKLVEGAVHEVKSCVIVDDVITTGGSTIQAIRSMRDSGIVVVQ
GVCILDRQEGGMDAILAEGVQMFPIFKKSDFGNLEHE
>LBL_4241 pyrF, Orotidine-5'-phosphate decarboxylase
MNFQSKFLTRSQSLKSLLCVGLDPDYCKLPEIIKRSPEPLVHFCREIIDA
TAPYAVAYKPNIAFFEVFGSSGIRQFEKVIGHLKNNYPQIPIVADIKRGD
LDNTARQYARYYFGDLQVDSLTLSPYMGLDTLRPFLEYQDHLVFWLCLTS
NPDSIQFQKKRFSETGRTLYEEVAYVANSISPLNLGFVVGATNTYELEIL
RKQNPDRIFLIPGFGAQGAKLDDLLPVCGRYSLINSSRGIHFASDGLDFA
ARANQEAEKIHNAMQARFVFL
>LBL_1675 pyrG, CTP synthase
MSRTKFIFVTGGVSSSLGKGVTVAALGCLLESRGYTVSLQKMDPYINIDP
GTMSPYQHGEVYVTADGAETDLDLGYYERFTHSKLSRKNSVSTGQIYNTV
IQRERKGDYLGRTVQVVPHITNEIRNRMYIVAREENPDFIIVEIGGTVGD
IESIPFLEAIRQIRYEHGSSNVLFVHLTLVPTITAAGEAKTKPTQHSVKE
LLGLGIQPDILVCRVSQPMTKEMKNKLSLFCNVKEENVISASDISTSIYE
IPKMYKEEKLDEVVLKTMGMELRESNFSEWDKMIRRLLATKQTVQVAIVG
KYISLQDAYRSIYESLSHGGIAYDTKVEFVKIDPENLNKDNVQSSLKNVH
GVLVPGGFGDRGIEGKILAIEYARTNGIPFFGICLGMQCAVVEYGRNVLK
LKDANSTEIRPDTEYPVISLLEEQNDIEQMGATMRLGSYPCKIKKDTLSY
SEYKSTLVHERHRHRFEFTNRYRKQYEENGMVISGTSPDDSLVEIVEIPK
HNWFVGVQFHPEFQSRPTKPHPLFAGFIRAAVKYSKKGSS
>LBL_0921 pyrH, Uridylate kinase
MGSKYKRILIKLSGEALAGEGEFGIDTNKAHSLAEEIKEVHDLGVEIALV
VGGGNIIRGTNLAKVGIDRATADYMGMLATIQNALALQDACEKKGLYTRV
QSAIEINSIAESYIRRRAVRHLEKRRIVIFAGGTGNPYFTTDTTASLRAV
EVGCDVILKATKVDGVYTADPKKDNGAKRYSQISFMESINRRLKVMDSTA
LSLCMENNMPIIVFDIFKQGNLKDLVTGKNIGTLISNSEDIQIDGK
>LBL_2320 tmk, Thymidylate kinase
MKIEKPIFVVFEGIDGSGKSTLCKSLTEKLTERGIPSVNFTEPTNFETGK
YLRKFLRGEIDLERKEQIDAFLNDREESLRQNILPSLESGKNVLLDRYMY
STAAYQSGDDLLPETIIEKNLKKNFKIPDLLFYLDLNPAIALERLSQRKE
NKERFETLAQLEKIRSAYNRILPKETIRIDGVKGPDEIVQECLEIFLRNF
NRKFL


# Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130

>LIC11870 hydrolase
MCVMEDSNSTQWDEPRKNLFSIHKLDYARGKRPDVDCILCGICRKDPEVP
NLTVAETNFTIVSVNLYPYNPGHLIVFPKRHILSYEELTKEEAMEIHEGT
VKAISILKKLWNVQGFNLGYNLGKNSGGSIPHIHEHIVPRFPNEAGFLDV
LANSRIVIYEPYEMQKEWIRIWKEFS
>LIC11383 conserved hypothetical protein
MLLETCRGKSMELFAVFAINAVVSVVLYYTITSKVTERIRTHMLGKINEE
IRDFIDELETESLRQVDLMGARILTFKEITSKAEELVKRIEQSTSPDILE
KIQIVDKDSVINNENKRSENLYPLKNGNHTGVSDSVQQGVGHIYKENLDL
TREDAENFSNLQKVSNSKIHTSYIQKLETTSKVVKKEVVSQNKPEILPQG
STSNLVLETIGKGIRKFFGIQEIKTIRSENETSGNDFFPGTRNSTLDISL
DENPFAPISESKLNETSSLVFKDNLKPKEADFGRILQENIVGYQPIKPDS
TKISAEAALLEIGDDSTKIEKVVFLLKRKYTHEEISEVLDLALGEVDIIE
RFRLDRNRRF
>LIC10601 conserved hypothetical protein
MSAKGISKDLIGTKLDHYEFDVERGKIREFCQAIGETNPIYFDVEAAKKA
GYEDTPAPPTYPTVIQFWGYPKIWQDMENMGVDTSRILHLKEKYTYLKPI
YPGRVSSQGECINVTVGKMDTMTFKTTIKNAKGETIVEQEMSIFIRKPEA
>LIC11447 conserved hypothetical protein
MRKFNGTEFYSFLFKSGCTMIEKIIEDFKDSVKESVKSVRIPLEVHSKTG
NYSAEIGGWEGTSMSLNLERFNLDSVGEPATLEVKIPFWKDPILLHGTIT
EKKIVRSRSQDRMTDNVLLFESDAIGLVKKFLPKFPLDLKEWKLLEFSKK
AVLPSYFPKNLRMWELI
>LIC10270 chlorohydrolase family protein
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGL
YVYPGLINGHDHLLSTYLPRVAPSKPYLNWLPWDNDLKSSIVFSERQQLD
PEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFIETMPVRILNRFTLSHSI
CTYSLDWGDGPEEEYAKALKQDIPYITCIAEGFDSESRDSLKNLYQLGCL
GEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYERTTDIKDVLKH
GVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNP
AKAFRIEKQLGSIEVGKIADLTILTRNFEDPYLNLCESNLNSIRLVLRDG
LPVYGDISLKSFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYK
KDLAFFPVQKEFDNFE
>LIC12614 conserved hypothetical protein
MNGIWDPKKLNVNCNGRDVSGMSQSDGFFKIEPVTKEYILSQVGIKGDWN
ISEIYDGRVKLSIALMGDSPENEFFFAMGEERLPCVFTIKDKSDGGMLGF
SAQGRVWERPNIEKGKEYKDKTWVFLLPDYKGVLTA
>LIC10680 conserved hypothetical protein
MYIAKIQVVLKESVLDPQGSTVKKVLSEVGEKSVQDVRVGKYIELKIDAP
SEEVARKDVERLCDKILVNHIIETYSMNIQKI
>LIC10257 MutT/nudix family protein
MKYCSSCGSSVTYKIPEGDNRSRHVCDQCGTIHYQNPKIIVGSIPIWENR
ILLCRRAIEPRKGFWTLPAGFLENRETVEEGAIRETKEEANAEINILGLQ
SVYSIPHISQIYMFFLANLVNGKFSVSSESEEIKLFSIEEIPWEELAFTS
VSFALRKYVDSSVKNSLHLGNTRDRKNLPKES
>LIC12227 conserved hypothetical protein
MKKRIVSTVLGLAIFAGTSLISNRAEAKGYGEAGCGLGSILISSKGFVQI
FAATSNGTSGNQTFGITSGTSNCTADGIVKLEKAQEMFVTVNYESLEQEM
AIGKGEKLESFAKLLGCDAGSVSRFGKLTKEKYSSLIKQETTPSLLLSAV
KSEVKGDTSLSKNCTL
>LIC10549 xanthosine triphosphate pyrophosphatase
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKE
NALIKAKELFYLTKIPSIADDSGICVSALKDEPGVYSARFGGPELNDEGR
ALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGI
YGFGYDPIFIFPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP
>LIC10196 conserved hypothetical protein
MIFISVALFAEAKPLIENLGLNILRNKTVFPIYQNENHALVISGTGKIYS
AMSVVFLLNEFKDQISDSSWILNFGVCGARKDISEIGKSFLIHKITDEGS
FKNVYPDILFHSPIPESALRTFDKPIFDDVVSELPNTLVDMEAFGFFTAS
RKFFSSDKIRVVKIVSDNLNKLEYSKITNIPEMISFRIQNSLSDILSILS
IPVFQKNNIQLLAEETSTLLQICEVLRLSETERIQLKDWMIGYKMRTGNS
PDLGLSILKNSNGFLKPGQTKVKTRELGKKGLYALKQFYQS
>LIC11581 conserved hypothetical protein
MGKVKFSERDLILFVDWKKMLPLILGIYFLYSSETMSEPNSFRWKDGEIV
VNGKAYNRQIYFRHKKLSHFANWENIEKLFLSPDKKSLVVYHRADKEKFY
RLTLFRFETRNHTLVRSIQPGMACHDLFWYRDKIIFKTGTTGGGTYLTYY
DKNLKKINEINSYHFYVDRSLGIALASPVYGPDDGKFWIYSLYSGKIIET
FDYKKEMNENYTITDLKKIGAHKFMIRISGYHTERTKTFIKNIPKMR
>LIC10353 conserved hypothetical protein
MKIQWFHYENEGYYLSVKNLNEPIESLNPLYLRITHFNQNIDKIIGFILD
RYLQYLDIGPLRECIFSILRETLMNAIKANQKRMVFKEAGLDIKDPDQYL
IGMERFKEELISKKDLYADLLEQNGLYVLITFGFNQNSFLLKVSNNVGIL
PEEDQRIQERISKARSYNDLSEVFENHGDESEGAGLGLAMSLLMLKNEGI
EGDSYRIKSEEGITSAYIKIPFEFKKRNINLQKTGDIFAELDTLPTFPDN
INQIMSLINKPDSSIQNITELVSRDVSLSTNILKLANSASFSQRARVEDL
EDAIKVIGLSELNNILLSLGTKKILEEKYNEFEAIWERSSLSAFICRRLG
ERMGWKKQTITVLVCAALLHDVGRVILLSIDPNVSAKISEILGNRLYPSP
LTLEEAALGISHTTLGGMICEKWNFSDTIRVAAEMHHRPLLVKREFQDTV
FAIYLSDMIIDISSGISDYSMIQSAVLQHFGFKKEEEFVEFMDKTLLEYK
NFP
>LIC11945 GMP synthase
MRSLIVRFKDCEGPGILLNSLKKRNYKITYHNAYDLRVKPLPDAHLVFDL
IVLLGGPQSVTDHSLADFFEPWLNLVRYAKSIPNCKVIGICLGSQIISKA
LGGEVKRGENGPEVGFYDVQVQEPHFLFDGISSFPAFHLHEDVFSIPEGT
KRLLKSEKYSNQMFSFEDRIFGIQCHLEITASMLSIWQKAHSDFIRSAGW
IPGPETEFLRSQMEKVGGSIFEKILDHSTGFETNHRALLSSQAMTAKSG
>LIC12559 conserved hypothetical protein
MDILLLDDGQKIQSSLIEGSVGTDSLLVPGVYWNRLNLQEKKALRNKLPF
LLRKYSKQIASMKRLHNKAGKIKYNRGVGKMKKLSIRVHSGVWATLGVLA
AAHGVSRCYLFNYMLWLDEQGDFFVKTLNRGVPIFHWTYKMIWKIDRRQN
FISRELQFEPNPMTNQYPYYLKE
>LIC13172 conserved hypothetical protein
MGKSNPSPRWEIFTSSYLQCFGKKISTETFFQDYQDPDSFRKFYQFNHRG
PFTEFQAKFNLIIALSKFDPAEISLVATRVVENQFLQGVTYGEYRLMYSP
LETEIGIYEKTLAACEGLALGEQKTGGLAKGKLVISLHRDGDVFQEYLIY
KNIMEKNSLIRNYLVGLDFCYIEEGFPPKGKRKFFQEVNRDNQAEKNTAL
AILYHVGESFQDKSILSASRWVLESAEWGAHRLGHAIALGLHPSEKMKDE
ITEPRSERLDQLQLYYDRKEELDSYFEVPSREKIGNEIDSLKHKETVKFN
ISPSFLEECIGFQNYCISKIKQTNAIIESCPSSNEYIGMVVNPESHPILR
FAKNDMKFTISTDDPGIFGTSIKEEFSKAAKIGLSTEVLETVRRNSFLFT
SEILSGKKSSSEFEVLESF
>LIC12313 HIT family hydrolase
MTDPNCIFCKIIRKEIPSKVVFENDEILAFYDISPQAPVHIVFIPKKHIP
SLSEIENEDSHLLGNILLQIRDTAKNLGFAENGYRVVNNTGKNGGQTVFH
IHFHLLAERRLHWPPG
>LIC10459 add, adenosine deaminase
MALTFQEILDRIRIIDRDVTELNRLKSRLPADRPYSSSLQISFDKQINEL
LNERVGLMELEVLDPPSWILGVPTTGISQETPVPLKGLFPSGDLSKEKPD
DQDVINFLRELPKTEIHLHLEACVNKDTMKRLMAKNGINVTDEEFEAKFN
FKDLNSFIQVFFFIQSLVKEPSDFSFFIESLAEYMRANNILYTEVFFAPS
KFIQNGLDFEEMIDFLVNRIREEKENDGIVIRLLVDVSRSFGPENAMKNL
DRVLKLRHPEVIGIGLGGAELMGPARDYQGVFQKAREAGLRVVAHSGEDD
GPWAIWEAVELLKAERIGHGTSAIQDPELVKYLRENHIPIEICVTSNVFT
GKYVRKEQNHPVRYYYDQGLPLSINTDDPEIFNVNLTYEYYKLWRFLDFS
LDEIVDLIRQGVFASFHPNKESLWAEMEKNIHLVKTRYGLKR
>LIC12852 adk, adenylate kinase
MKNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEA
KRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQAEALDTL
LKNEGKSIDKAINLQVPDAELLKRLLGRAEIEGRADDNEVTIKNRLDNYN
KKTLPLLDFYATRKKLSQVNGVGSLEEVTSLIQKELA
>LIC20142 apt, adenine phosphoribosyltransferase
MSIVKSKIRTIPDYPKPGILFRDITSLLLDPEGLALTIGTFVNRYQGKGI
TKVAGIEARGFLTGAPLAFQLGVGFIPIRKKGKLPSETVSEEYDLEYGKD
VIEVHKDSIQPGDKILLMDDLIATGGTMIAAVKLLKKLGAEIYEAGVIID
LPDLGGRKKLQEELKVPVFSICEFEGH
>LIC12466 carA, carbamoyl-phosphate synthase small chain
MMKAFLVLDNGTIFEGESFGYETESVGEIVFNTSMAGYQEILTDPSYCNQ
IITLTYPMIGNYGIHPDNMESSKIQASGLIVKEYVDLPSNFKSEKTLSQF
LKEYKIPAIQGIDTRKLTRFIRTNGSPNGGIFVASEYSPSFLEKVKSFPG
IINADLAEVVTTSSKYIFGTHTGKKFKLAVYDYGVKTNILRLLDANGFAV
TVYPAKTPSEEIMKEGTDAFFLSNGPGDPAPLDYAIASTQKIMEKRYPLF
GICLGHQIIGLSLGKKTEKMKFGHRGGNQPVKNLETGQVEITSQNHGFAV
IDDQKQDEPISFLNLNDHTVEGILKSGYPLLTVQYHPESAPGPNDSRYLF
QKFYDLVEKTKKG
>LIC12883 carB, carbamoyl-phosphate synthase large chain
MPRREDIRSVLILGSGPIVIGQACEFDYSGTQAAKALKEKGIRVILLNSN
PATIMTDPDLADATYVEPMTVPVVQKILEKEKPDAILPTVGGQTALNLAL
ACNSAGILEKYNVELIGAKVDAIKKAEDRELFKKAMEKIGVRVPASGLAN
NLKDAVEIKNKLGLPLIVRPAFTLGGTGGGIAYTEETFEEVVSKGLKASP
ISQVLLEESVLGWKEFELEVMRDLADNVVIICSIENIDPMGVHTGDSITV
APQQTLSDKEYQNLRDMSIAIIREIGVETGGSNIQFAVNPTNGDVIVIEM
NPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIKNDITRVTPASFEPS
IDYVVTKVPRFAFEKFPGTDDTLGVQMKAVGEAMAIGRTFKESFQKALRS
LEIDRYGFGSDGYFQELLYSRSLNNDQRKEWIDSHLKRPNDKRIFYVKLA
FDEGYTVDQIHDLCKIDRWFLWQMEGLLKLEKEYSEKGNSILYKMKQVGF
SNRQLSFLKNKKQILDLLDGNLRVDLKKTEIQNLLKLSEEEIEVELGSKK
ILPVYKRIDTCAGEFEAYTPYFYSSYDEEDESDVTNAKSVMILGGGPNRI
GQGIEFDYCCCQASYALQDLGIESIMINSNPETVSTDYDTSDRLYFEPLT
LEDVYRIYQNEKPEGVIIQFGGQTPLKLAKDLEKKGVKILGTSPDSIDRA
EDRKRFVEVLEKLKLNSPESGIATSMEEAREIAHKIGYPVLVRPSYVLGG
RAMLIINEEKELDRYMEKAEEISKDRPLLIDSFLEDAIEVDVDALCDGKE
VFVTGIMEHIEEAGIHSGDSACVLPPQTLSKNMMDEIRKATVNLALELQV
KGLINIQYAVKNEILYIIEVNPRASRTVPFVSKALGHPIVKYATRIMMGE
SLKSLPLPKEMEFSQVSVKEVVLPFNKFPGVDTILGPEMRSTGEVMGIAS
TAGEAFLKSQYMAGDELPSQGTVFVSINDKTKAELLSYIKDLSELGFNLI
ATSGTHKFLSDNGILSSKINKVYDGIFPTALDYIRENKIHLIINTPLSRV
TRDDSFTIRQAAIRFKVPCLTTSNAAKALIKGMVEMKNKGFTIHSLQEIH
AMPKIL
>LIC13472 cdd, cytidine deaminase
MSKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIR
TDNKILSDFLNKLENLVTRYREEIPSFTRIYHKEKLISETFNEVEKKSDS
SFHSEILCIRNAKEKLKTRYLADCMLITSLEPCLMCAGTILLSRIPKVVY
LLPAKQGEGISSLSIEMIYSRNFFPELFCIPTEISKNAFKSFFKVRRKKF
N
>LIC10065 dcd, deoxycytidine triphosphate deaminase
MILTGKEIQKRIGNDIVITPYSEKQLNPNSYNLRLHEELLVYTELPLDMK
KPNPAEKLVIPESGLLLKPGILYLGRTLESTETHNLVPMLEGRSSIGRLG
MLVHVTAGFGDVGFKGFWTLEISVIQPLIVYPGVEVCQIFYHTLEGQITE
YTSGKYQANRGIQTSMLYKDFEK
>LIC11663 dgt, deoxyguanosinetriphosphate triphosphohydrolase
MYFSRDDLLQKETETLAPYAISNANNGGRIYEEEEHSYRLPFQRDRDRIL
HSSAFKRLQYKTQVFIFSVGENYRNRMTHTLEVAGLSRTIASALGLNSLL
SESIALAHDLGHTPFGHAGQEILSGLMKDYGGFEHNKQSLRIVTSIEKKY
PNFPGLNLCRETLKGLMKHGADYDSSVILLERKENGPSLEGMIADLSDEI
AYTNHDIEDGWEMGYLHLGDLLENPFWKEVYEECKDQYKEVGEKILIRTS
IRTLTNFLVSDLIQNIAHRLEKKQIKSTEDLALLWKQDFRIASFSKEVDL
KFRELKSFLYEKLYRHEDLIRMSDYGKKIIESLFDYFLKHPEKIPDTYKE
RIEEESLYRVISDYVAGMTDRYAEKIYQSLP
>LIC12560 dut, deoxyuridine 5'triphosphate nucleotidohydrolase
MKIFVQKLRPNAELPLLQTKQAAGYDIHACLDSKLVLEPGNVGLVPTGLS
FAIPQEFHFEIRPRSGFSTKNRILIPNSPGTIDSDYRGELMIPLLNLGDS
SFIIEHGMRIAQLLIRKTWYADWELVSEFADRTERGANGFGSTGH
>LIC11831 guaA, guanine monophosphate synthase
MVIHKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPISNYQKYSGII
LSGGPESVYEPNSPTVTTRIFDLGIPILGICYGHQLIMKLLGGVVERSGT
GEYGPASLQLHGTNGNSILKNFVGGEQVWMNHADEVVKLPEGFSKIAFSK
DCGYAVVANSSKKIFGIQFHAEVSHSEKGSVLLDNFIQICGVSKTWGIDQ
FLKEKIKEIQETVKQEQKIFMLVSGGVDSTVSYLLLCKALGAERVLGFLI
DTGFMRKDEVVSLQKKLTFQNIHLTVRDESSLFYKSLKDKSDPEEKRKIV
GNLFLEARDRAVKDLDLEYGDWLLGQGTIYPDTIESGGTKHSHTIKTHHN
RVEAIQKLIEQGKVIEPIRDLYKDEVRDLGVLLGLESEWVGRHPFPGPGL
VVRMLAVEKKGTDKDQLEIDSYLSTQDGLSGKILPIASVGVKGDRRSYAN
CVVLNDIETDWNTLDRVATHLSNRFSFINRVVLLPFESDLKKWNFQFTGM
QLDKKCSDLLREADFTVESVIRKLGLYNKIWQMPVVLLPIGEKENEKSIV
LRPVESQEAMTANFFRMERSVLQEIKIEVLKIPEIRYLFFDLTNKPPGTI
EWE
>LIC13438 hpt, hypoxanthine-guanine-xanthinephosphoribosyltransferase
MKKINSDILHPRFSREDISQKVKSLALQISEDYKKLNPIFICVLKGGVYF
FTDLTREIPFSVEINFVQARSYSGTVSTGKIELLKDIDIDLSDRHVIIVE
DILDTGFTLQYLVRHIFTRNPASLEIVTLLLKERKDTLEFPVKYIGWRIP
DEFLVGYGLDFDGRYRNLPDIHVLEPGEPQFPV
>LIC13399 mtaP, 5'-methylthioadenosine phosphorylase
MSYNVRVAIIGGTGLYSLEGMELIEEIFPDTPWGKPSDKIKIGKYKGKLI
AFLPRHGIGHFLSPPEVPNHANICALKQLGVEEIVAFSSVGSLREEIKPL
DFVLPSQIIDRTRFRNSTYFGNGVVAHAPFAEPFSPNLSKRIAQTAKKIG
LEIHLDKTLVCMEGPLFSTKAESHLYRSWGADIINMTVLPEAKLAREAEI
AYQMICMSTDYDCWREGEESVTVEMVIANLTKNAETAKKLLSELIHVLGN
GDDLSLKNSTRYSIITAPEKRNPETVKKLRVLFPEYF
>LIC13326 ndk, nucleoside diphosphate kinase
MSRTFIMIKPDGVKNKHVGNILSRIEKEGFKILGLKYLKLSLEDAKQFYK
VHSARPFYNDLCNYMSSGPIVAAALERDNAVLHWREVIGATDPKEAAAGT
IRALYAESKEANAVHGSDSDDNAALEISFFFKGNELF
>LIC11587 nrdA, ribonucleotide reductase protein
MLWSKKKFMKMNRHFTVPQNGESSTIQWTKRNSKITNPDGSKVFEANDIL
VPEDWSQVAVDILAQKYFRRKGVPKYLKKVQEDGIPEWLQKSIPDTEKLE
SLKPEDRFGGETSALEVFHRLAGCWTYWGYKYKYFSDEESAKIFYDEIVY
MLATQMAAPNSPQWFNTGLNWAYGIDGKSQGHYYVDPSTGKLVKSTSAYE
HPQPHACFIQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRGEN
EPLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIEN
FIDWKVTEEKKVASLVTGSMLNNRHLNAIMSACYEMEGEDRFNPKKNSSL
KKTIQDAKKVLIPDNYIKRVIDLARQGYKEILFEELTTDWQSDAYNTVSG
QNSNNSIRLTNEFMAAVEQDQPWNLYFRTEKEKAKVEGRKAKPSQTLRAR
ELWEKISYAAWASADPGTQYHTTINEWHTCPEDGPINASNPCSEYMFLDN
TACNLASANLQKFVNLETLNFDVEGFRYLCKLWTIILEISVTMAQFPSKE
IAELSYKFRTLGLGYANLGSVLMVLGIPYDSQQAMAITGAISSIMHMTAY
ATSAEMAKEQGPFVGYAKNQKHMLRVIRNHRRAAYNAPSGDYEGLTITPI
GINPAFCPSYMLKAAQEDADLALSLGEKYGFRNAQVTVIAPTGTIGLVMD
CDTTGIEPDFALVKFKKLAGGGYFKIINQSVPYGLKKLGYSPSEIEAIVN
YCKGHATLNGAPVINTQALKEKGFTNEILEKVEASLPLAFDINFAFNKFN
LGENFLTKNLGISKEIFDSPGFSLLEHLGFTKEDINKANDYVCGTMTIEN
APFLKEKDYPVFDCANKCGKYGKRFLSYESHIRIMAAAQPFISGAISKTI
NLPEEAVIEDIKNAYFLSWKMMIKANALYRDGSKLSQPLNSVLELLNGIE
IDDQEEIREATISKDPVQIAEKIVTKYISHRRKLPSRRAGYTQKAIVGGH
KVYLRTGEYEDGQIGEIFIDMHKEGAAFRSLMNAFAISVSLGLQHGVPLE
EYVDAFTFFKFEPNGIVSGNKHIKMSTSVIDYIFRELAITYLGRYDLGQV
APEDLRGDEIGSKRATAESNGQEKETLSSMTAVIEPTPKKEVETISYSQM
ISKEKPSSSPSGISLLEEVKLAKIKGYTGDSCSECGSFEMVRNGSCLKCM
SCGSTTGCS
>LIC11257 ppx, exopolyphosphatase
MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENG
PIDPESFRRGIDCLKRFKILAENAGAEIRAVATSALREASNQEDFLENAY
QEAGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGH
RGNILFSKSFKLGAIRLSEKFFKEETLSNSDVRKCRLYIEEMLLPFRKIL
RDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFTSSEFKKIRNL
ILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFAL
REGIVYDTIRKWEHFENTEHSKHLDDIRQTAVHNFMKSFSRDEEFSKHVA
ELSLQIFDQLKSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI
RNSEMLLGFTFLEIEIIALTARYHRKNTPKIKHREFNKLAEKNQTLVCQL
SAILRISSALNRNRGGLVSSVICKIEKNQIRFILESSKGYDPSLEIWAAE
EQKVAFEETFGYSVEFVTGT
>LIC10429 prs, phosphoribosyl pyrophosphate synthetase
MNGDIAVFAGNSNKQIAEEICTHLGIQSGKINLKKFSDGEISVKIEDNVR
GKEVFIVQSTSAPANDHLMELILIMDALRRASVSSISVVIPYYGYGRQDR
KVEPRVPISARVVADLIEVVGLDRILTMDLHADQIQGFFRVPVDNLHFAP
VLAEYVNTKKIDDLVIVSPDSGGAERARAFGKKVNGSLAIIDKRRPKANV
SEVMNVIGEIEGKNCILLDDMIDTAGTICKAADVLLKHGAKSVYCAATHG
VLSGEAVDRINSTQFSEVVLANTIAIPESKKINKLKSLSVAPLFANAIQR
IHTNQSVSTLFD
>LIC12565 purA, adenylosuccinate synthetase
MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKY
VFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECDRLQKEGFPVFDKLLLS
DACHLLFPYHSQIDSARETTLSQEHKIGTTKKGIGICYADKMMRTGLRVG
DLLDTSYQTRLKHLVDEKNRELDKLYGMPPVSYNDINEGLKFFLSKVKKN
IINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNPTTGGALI
GTGIPFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEKLRQKGGEFGAT
TGRPRRCGWFDVEMLKHSVRINGITSIALTKIDILSDYDTIPVATGYKLN
GKTLDCFPSQGLDKVEVIYEEFPGWKSDISGICEFQKLPEKCKNYISALE
KWIGVKINLVSTGPDRKDTIHGDSF
>LIC11016 purB, adenylosuccinate lyase
MIDRYSNPEISKIWELENKFEIWKEIEILACEIRMKRGEVPQEDFQEIKS
KAKFNVDEILEIESKVHHDVIAFLTNMNSYIGPAGRHVHYGLTSSDIGDT
ALCVQMVQAMDLILKKTDSLIEVVREKAIQYKNLPCIGRSHGIHAEPMTL
GLKFALFFEELNRNRKRMAEARNEIAVGKLSGAVGTYSNIDPEIETYVCE
KMGLRVDPIATQVVSRDRHAFYLSVLGVTASSLDRMATEIRLLQKTEGRE
VEEPFSAGQKGSSAMPHKRNPVICERISGLSRVIRANVNVGLQDVALWHE
RDISHSSAERVVLPDSTIALEYILDKMLFVIKNLHVYPDAIERTLGVTRG
LVFSQKVLLALIEKGKIIREEAYLIVQEHAMAVWASQSETLKSRLEKDDR
VSKVLTQKDLDDIFKIEPYLEKVGLIYKRLGLE
>LIC10679 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MNPSYKGKVRDIYDLGDKLILSSSDRISAFDVVFPQLVPDKGKVLNRISV
SWFEFFKDVPNHILETDVKYFPIPFQNHPDLEGRSVLVKKCKRIDYECVV
RGYISGSGWKEYKNDGTLAGIKLPSGFKESQKLPEPVFTPAVKNDQGHDE
NISEKEMENRIGKELFNILKEKSISIFLRASEVVDKAGIILCDTKFEFGI
LDGQVILIDELLTPDSSRYWSTDTYSVGISPPSLDKQILRNYLETTSWNK
MPPAPNLPAELIQELREKYQKIEDLILSCTSQKSK
>LIC10472 purD, phosphoribosylamine--glycine ligase
MQVKLKVLLIGSGGRESAIAFYLRKSVLLSELKVFPGNGGFPDQELLPPD
SFQVLDKNSVQSFLKQNPFDLIVVGPEDPLVAGFADWAAELNIPVFGPDS
FCAQVEGSKDFAKSLMTEAKIPTAEYKTFSEYSDSLKYLESKSIPIVIKA
DGLAAGKGVTVATSKEMAQTALKEIFKDKKFGSSGNQVVIEEFMEGQEAS
IFAISDGDSYFLLPAAQDHKRAFDGDQGPNTGGMGAYCPAPVISESILQK
VKEQIFDPMFDLFRKKGHPYRGLLYAGLMISPNGEPKVVEFNCRFGDPET
QCVLAMLDGDLLELLYRASTGKIKGIQAAVKKGAAVVVVLAAQGYPDFYE
KNIPLNLPETSGQNVHLFHAGTLKKDGKVFSSGGRILGIVAQGADLKSSV
DQAYSFLEKIQAPKTFYRKDIGYRAL
>LIC12292 purE, phosphoribosylaminoimidazole carboxylase catalytic subunit protein
MNTKVAIIMGSHSDWETMKEAEIILKEFGVSIHKEIVSAHRSPELMLEFS
KSAKEKGYSVIIAGAGGAAHLPGMVASMTTLPVLGVPIQSKTLNGLDSLL
SIVQMPGGVPVGTLAIGTAGAKNAGLLAVRILALQDPILSEKLERYRNQI
REDALSKNKDLL
>LIC13262 purF, glutamine phosphoribosylpyrophosphate amidotransferase
MSRIPDKSRIRRQAQDDKPKEECAIFGIFNSSEASNFTYLGLYSMQHRGQ
ESSGIVSSDGEHLYRYAGMGLVAHIFTETKLKELQGNAAIGHNRYSTTGA
SFLRNAQPLRVESHLGAVSLAHNGNLVNSWELRSQLEKEGSIFQTTIDSE
VIVHLMARSGETDFLSALSSALKKVRGAYSLVILTKTQLIAVRDPNGFRP
LVMGRREDGSIVFASETCAFDITDTKYERDVEPGEMIVVDKNGMNSYYPF
PKASPSLCIFEYIYFARPDSSIFGESVYKVRKNLGRFLARELPVPADVVI
PVPDSANIAALGYAEESGISYQSGLIRSHYIGRTFIEPDQKIRDFGAKIK
YNVVRNVVEGKRVIVVDDSIMRGTTSRKIIKMIRNAGAKEIHLRVSAPPT
ISPCYYGIDIPTHNELIAATHTIEEIRKYLRVDSIAYLSVESMNRAVMDH
KGGGFCNACFTAQYPVEFQSELGNQKSLFKEYQVEERVVY
>LIC11655 purH, PurH
MIQIKRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIA
IDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLV
VVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPN
DYKEIQNLISSSGISEEISASYMRKAFSHTAMYDAAISSWFYKQSGEVFP
DVLNLSFIKKQKLRYGENPHQAASFYEPLFTKSDFSPLQGKELSFNNMLD
FDAAFHISSLLPENTVCIIKHLNPCGIAYADNPLEAFQLARRTDPISAFG
GVIGIKGQVNGELATSITENFVEGVIAQKFTQEALEVFSKKPNIRLIEIQ
DFKEALDELDLRPIHHGLLIQDRDYTTITEKDLKVVTKKQPSPDDIRGLM
FAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGANKALNVGLSV
VGSYVASDAFFPFRDGIDTLAKAGAKAIIQPGGSVRDEEVIQAADEHGLI
MVFTGMRHFRH
>LIC12293 purK, phosphoribosylaminoimidazole carboxylase atpase subunit protein
MNNSRMLLPGSRLGVMGSGQLARMFCLEAIPFGYEISVYSPEKNSPAAGA
GAKEYISTYEDEKALTFFLENIDGLTFEFENIPEIALTTIENFSKRTGLI
VRPSPNCVRISQNRWKEKTSFQKAGIPTVKFYPVLTEEDKKSVLSKTNFP
CILKTNTMGYDGRGQIRCITEQELSLVFSNLNKPDHIVEEFFQFTSEASV
IMARFEDGKILNFRPSKNVHKNHILDLTFYPGNFPDSIETKLVNYAKKLA
ETIDYVGVFGIEFFIRGDEILCNEFAPRPHNSGHFSQNSGTISQFSLQLR
TLCNLPSPKTILANPVSMKNILGEDYKPGSTLWNKTLENPYYHLHLYGKT
EIRNGRKMGHWNYSGPNIESAFLNWD
>LIC10681 purL, phosphoribosylformylglycinamidine synthase
MKIAVITFPGSNCDSDIYRVLKDQYNAEVDRIWHRDGLDKKYELVILPGG
FSYGDYLRSGAMAGFSPVMKSVKEHVDKGGKLFGICNGFQILTEAEYLPG
ALIRNKTLKYICKTVILTKGSAGNPVTASMDVRKELKIPIAHADGCYYAT
SDVLKQLEDEDRILFRYSGENPNGSLDSIAGITSKNFKIVGMMPHPERAM
NPITGEMDGKVVLDLILGS
>LIC11123 purM, phosphoribosylformylglycinamidine cyclo-ligase
MDTEKGREFIQKIKRNVESTHGPRVIGGLGGFAGAYDVSVLKKYKHPILL
SGTDGVGTKIELARLLKIYNTIGIDLVAMCVNDILVCGGEPFFFLDYIAC
GKLDPEKMDQIVSGIVQGCKMSNASLLGGETAEHPGTMKEDEFDLAGFVV
GAVEKDSMIDGSTIRSGDKILGLESSGPHSNGFSLIRKLLLKEGKYLPTD
PQQVKFLKDYALKPTRIYVSSILKLLQQVSVKGMVHITGGGYQENIPRIL
PQGTQSKFFKEKIPSGYFFEKIKKDHKIEELELFATFNMGIGYMVIVSEE
NAELAKKIMESSGEVVHEIGEIVSGNKEEVQFV
>LIC11656 purN, phosphoribosylglycinamide formyltransferase
MATLFTKPKKKIVFLASGRGSNLRAVLQNIKVGKIRGIAQILICDHPDAK
ALEVAQEFELTSQVLNFSSFSNKSEYHTKLLQLLLEIKPDLIVTAGYMRI
LKSPVIQTFSNRIINIHPSLLPAFPGLNAQKQALEYGVKIAGCTAHFVDE
GIDSGPIILQGVVKIEEGMTERDLTLEILKEEHKILPLAVQYFCEDRLTI
QNRKVKIG
>LIC12402 purQ, phosphoribosylformylglycinamide synthetase
MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSY
KNSILKLKTLPTTSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAV
EPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPKNKYLLSRAVK
GIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGVVRHDQMASATTGG
QVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLL
MEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRE
TGMNAYEAMLSESQERMLVVPKKGKESELVSIFEKWNLNAVKIGEVTADG
MIEIYMGGKLKAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIP
DVTKGANSKEILLKILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLS
AIPGTNKALATATDCNSRYTYLDPYKGAEFAVCEAARNVYVTGATPYGVT
NNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGP
IFPTPTIGMVGILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKI
HGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSLGGIAVALSKT
VLFSGLGIESDLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEA
YGLKFYPIGKTNSSGILEIKDAEIKISFQELSGPYEKGLEAVFAL
>LIC13413 purT, phosphoribosylglycinamide formyltransferase 2
MKKKILLLGSGELGKEFVIAAQRLGQYVIAVDSYDDAPAMQVAHEKEIIN
MLDGNLLDQIIAKHKPDLIVPEIEAIKTERFYEYEKQGYQVVPSAKAANF
TMNRKSIRDLAAKDLKLLTAKYAYASSIDELIKATEILGFPCVVKPLMSS
SGKGQSVIQSREEISKAWEASQTKGRAGAAEIIVEEFIPFESEITLLTVT
QKNGKTLFCPPIGHRQERGDYQESWQPAAISEVQLKEAQRMADAVTKELT
GFGIWGVEFFLTEDKVYFSELSPRPHDTGMVTLAGTQNFNEFELHLRAIL
GIPILEITLERKGASAVILASTENKTPEISGLDIASGMSESDFRIFGKPI
TRPYRRMGVTLSYSTKGEEISSLRKRAVLLASKIKVD
>LIC12839 pyrB, aspartate carbamoyltransferase
MSKGSFFTFCRLMYYNHKNVLDTEQFSKPDLDFLIGKIRVMERLVEQNKA
FGILTGKLLASLFFEASTRTRLSFEAAMERLGGRVISTVGFQFSSISKGE
TLYDTMKMVEAYADIAVIRHPVEGSSRIAAGAVKIPVINAGDGAGQHPTQ
AILDLYTIISEKGTLDGLKVAFIGDLKYGRTIHSLINLLRHYKVRLFLIS
PPELALPESYKKALQGYSLTLEETTDIKAVWDCDVAYVTRIQEERFPDHK
EYERLKDLFKINKELILASKKETTVLHPLPRVNELSTDVDDLPNAAYFRQ
ARYGVVSRMTLLCLSLGQDF
>LIC10574 pyrC, dihydroorotase
MIKKISGRIVTHEKDFLGTVEWDSKTGLILTVLEQKESIPILNSQHQENE
IQFNSLETVIFPGFGDIHIHAREDESGKHTYKEDFVSASAAAVNGGVIHV
ADMPNNPIPPIDENSYSKKRKLADRSNIHITLYAGIGPDTKPLKKSVPYK
VFMGPSIGELFFHNNQTLEDTISSYVGENVSFHCEDPEILEKHQNETFHE
DRRPAEAETTATDFALYLIEKYNLRGKLCHYSTGEGLNKIKFAKQKGVKV
TCEVTPTHLFFDRSMLTPENRHWFQMNPPLRSKEDRERMLEGVKQGWIDY
LATDHAPHSIEEKRKGTSGISQLDTYSLFVTWLVLKAGVELKTVARICAK
NPGDFVNEYLPEKFGKGFGRIEPGYSANFTVLNLKKPKKFLKEEIKSKSG
WSPFENFEFPGSIEAVFFLGKQMK
>LIC13433 pyrD, dihydroorotate dehydrogenase
MINRNKIVLEMFLPHLRQSAYSVFLKPFFLSLDPETAHELAKNFLGIGQK
FPGFLTLMESMTSYQSDRLKTKIAGIEFENPLGMGAGFDKTGELYPFLSR
MGFGHIEVGTITGQKQSGNPKPRVFRYPQDQALVNRMGFNNPGADSAKKI
ISSQKKTKIRGINAGKTKIVPEEKAVEDYVYTLKKLSPYADYAVINISSP
NTPGLRNFQKQENFVSLIQGIRKDLGKNFKIPLFVKFAPDMETKELEALL
ETSLSLKINGVVLTNTTIDKSCLKNYPNVEKEGGLSGTPLKNRSTEFVRI
AYRILKRRIPIIGVGGIDSEKTALEKILAGADLIQIYTGYIYQGPFLPMR
ILKFLDRFLEKQDLKTVSDLVGKEKEIRLDQK
>LIC11076 pyrE, uridine 5-monophosphate synthase
MLKKELSMKQELLELIRTHVYRYSEQPFTLASGRKSRHYFNCKEITLVPD
RLELLCKFIVEQHLGESGILLPHAFGGLTMGADPICYGISLEFRKQNKNV
YPLIVRKLSKDHGTKKLVEGSAHLVKQCVVIDDVITTGGSTIQAIRSLRD
CGIEVVQGVCILDRQEGGKDAILAEGVEMFPIFKKSDFGNLEHE
>LIC11540 pyrG, ctp synthase
MEYTLSRTKFIFVTGGVSSSLGKGVTVAALGCLLESRGYTVSLQKMDPYI
NIDPGTMSPYQHGEVYVTADGAETDLDLGYYERFTHSKLTRKNSVSTGQI
YNTVIQRERKGDYLGRTVQVVPHITNEIRNRMYIVAREENPDFIIVEIGG
TVGDIESIPFLEAIRQMRYEHGSSNVLFVHLTLVPTITAAGEAKTKPTQH
SVKELLGLGIQPDILVCRVSQPMTKEMKNKLSLFCNVKEENVISASDIST
SIYEIPKMYKEEKLDEVVLKTMGMELRESNFSEWDKMVKGLLTTKQTVQI
AVVGKYISLQDAYRSIYESLSHGGIAHDTKVEFIKVDPENLNKDSYVEIL
KKVHGILVPGGFGDRGIEGKILAIQYARTNGIPFLGICLGMQCAVVEYGR
NVLGLKDANSTEIRPDTEHPVISLLEEQNDIEQMGGTMRLGSYPCKVKEN
TLSYSEYKSILIHERHRHRFEFTNRYRKQYEENGMIIAGTSPDDNLVEIV
EIPKHNWFIGVQFHPEFQSKPTLPHPLFAGFIRASVKYSKKG
>LIC10852 pyrH, uridylate kinase
MATEAKYNRILIKLSGEALAGEGEFGIDTNKAHSLAEEIKEVHDLGVEIA
LVVGGGNIIRGTNLAKAGIDRATADYMGMLATIQNALALQDACEKKGLYT
RVQSAIEINSIAESYIRRRAVRHLEKRRIVIFAGGTGNPYFTTDTTASLR
AVEVGCDVILKATKVDGVYTADPKKDNGAKRYSQISFMESINRRLKVMDS
TALSLCMENNMSIIVFDIFKRGNLKDLVTGKNIGTLISNSEDIQIDGK
>LIC12232 thyX, thymidylate synthase
MITSEKSIEIRDKVAKSTKKAGHLTTRQHPQFIFTLDKVSRQFVWSFLHS
HPFYNSEQVSQRYVEVKKENYYIPPELDGKLLELYLDAVDFASQSYFSYT
EALHPFIQEEYFQIYKARANYPDKWQTPIKKKCLEVARYLLPLGTFTYLY
HSVNGLTLHRYYRLMNSYDVPNEQRAVITEMINQVRAIDPLYADEMDDPV
PLEETTEYRYFDSMFGNGKREFHPETASTFVKEFDLELGERYSKLVSHSS
NGPEILAQSVRSILGIPKSILNDQDAIDLVLNPAKNRHLTSTLNESSMSP
ITRALFNVQYSFQKRISHTADSQDQRHRMVPGGRPVLMSQYAGIPDYITP
FVVQKYPELKEKYDVVHREIFEKLNRFLEAGGSPEHGTYLLPNSFPIRFY
ESGDLLNLHHKWRSRTCYNAQEEIFQASVDELTDVMKVHPQIAKWIKAPC
WIRLQGEVKPYCPEGDHYCGTQVWKRELSEYSRVI
>LIC12814 tmk, thymidylate kinase
MKNKKPIFVVFEGIDGSGKSTLCKSLTEKLIELGIPSAAFTEPTNLETGK
YLRKFLRGEIELGKEEQIEAFLNDREESLKQNILPALNSDKNVLLDRYMY
STAAYQSGDDLSPEMILKKNLNRNFKIPDLLFYLDLSPSIALERLNRRKE
GKERFETLAQLEKIRSAYEKILPKDTIRIDGNKNQNQIVQECLEIFLTNI
KSKS


# Leptospira interrogans serovar lai str. 56601

>gid:7005    probable Methylthioadenosine phosphorylase
MSYNVRAAIIGGTGLYSLEGMELIEEIFPDTPWGKPSDKIKIGKYKGKLI
AFLPRHGIGHFLSPPEVPNHANICALKQLGVEEIVAFSSVGSLREEIKPL
DFVLPSQIIDRTRFRNSTYFGNGVVAHAPFAEPFSPNLSKRIAQTAKKIG
LEIHLDKTLVCMEGPLFSTKAESHLYRSWGADIINMTVLPEAKLAREAEI
AYQMICMSTDYDCWREGEESVTVEMVIANLTKNAETAKKLLSELIHVLGN
GDDLSLKNSTRYSIITAPEKRNSETVKKLRVLFPEYF
>gid:5261    hypothetical protein
MRKFNGTEFYSFLFKSGCTMIEKIIEDFKDSVKESVKSVRIPLEVHSKTG
NYSAEIGGWEGTSMSLNLERFNLDSVGEPATLEVKIPFWKDPILLHGTIT
EKKIVRSRSQDRMTDNVLLFESDAIGLVKKFLPKFPLDLKEWKLLEFSKK
AVLHSYFPKNLRMWELI
>gid:4169    HIT family hydrolase
MYGEFRMTDPNCIFCKIIRKEIPSKVVFENDEILAFYDISPQAPVHIVFI
PKKHIPSLSEIENEDSHLLGNILLQIRDTAKNLGFAENGYRVVNNTGKNG
GQTVFHIHFHLLAERRLHWPPG
>gid:4273    Orotate phosphoribosyltransferase
MKKRIVSTVLGLAIFAGTSLISNRAEAKGYGEAGCGLGSILISSKGFVQI
FAATSNGTSGNQTFGITSGTSNCTADGIVKLEKAQEMFVTVNYESLEQEM
AIGKGEKLESFAKLLGCDAGSVSRFGKLTKEKYSSLIKQETTPSLLLSAV
KSEVKGDTSLSKNCTL
>gid:6262    unknown protein
MYIAKIQVVLKESVLDPQGSTVKKVLSEVGEKSVQDVRVGKYIELKIDAP
SEEVARKDVERLCDKILVNHIIETYSMNIQKI
>gid:7052    Hypoxanthine-guanine phosphoribosyltransferase
MKKINSDILHPRFSREDISQKVKSLALQISEDYKKLNPIFICVLKGGVYF
FTDLTREIPFSVEINFVQARSYSGTVSTGKIELLKDIDIDLSDRHVIIVE
DILDTGFTLQYLVRHIFTRNPASLEIVTLLLKERKDTLEFPVKYIGWRIP
DEFLVGYGLDFDGRYRNLPDIHVLEPGEPQFPV
>gid:4824    GMP synthase
MKLLGGVVERSGTGEYGPASLQLHGTNGNSILKNFVGGEQVWMNHADEVV
KLPEGFSKIAFSKDCGYAVVANSSKKIFGIQFHAEVSHSEKGSVLLDNFI
QICGVSKTWGIDQFLKEKIKEIQETVKQEQKIFMLVSGGVDSTVSYLLLC
KALGAERVLGFLIDTGFMRKDEVVSLQKKLTFQNIHLTVRDESSLFYKSL
KDKSDPEEKRKIVGNLFLEARDRAVKDLDLEYGDWLLGQGTIYPDTIESG
GTKHSHTIKTHHNRVEAIQKLIEQGKVIEPIRDLYKDEVRDLGVLLGLES
EWVGRHPFPGPGLVVRMLAVEKKGTDKDQLEIDSYLSTQDGLSGKILPIA
SVGVKGDRRSYANCVVLNDIETDWNTLDRVATHLSNRFSFINRVVLLPFE
SDLKKWNFQFTGMQLDKKCSDLLREADFTVESVIRKLGLYNKIWQMPVVL
LPIGEKENEKSIVLRPVESQEAMTANFFRMERSVLQEIKIEVLKIPEIRY
LFFDLTNKPPGTIEWE
>gid:5504    Exopolyphosphatase
MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENG
PIDPESFRRGIDCLKRFKILAENAGAEIRAVATSALREASNQEDFLENAY
QEAGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGH
RGNILFSKSFKLGAIRLSEKFFKEETLSNSDVRKCRLYIEEMLLPFRKIL
RDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFTSSEFKKIRNL
ILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFAL
REGIVYDTIRKWEHFENTEHSKHLDDIRQTAVHNFMKSFSRDEEFSKHVA
ELSLQIFDQLKSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI
RNSEMLLGFTFLEIEIIALTARYHRKNTPKVKHREFNKLAEKNQTLVCQL
SAILRISSALNRNRGGLVSSVICKIEKNQIRFILESSKGYDPSLEIWAAE
EQKVAFEETFGYSVEFVTGT
>gid:5343    hypothetical protein
MLLETCREKSMELFAVFAINAVVSVVLYYTITSKVTERIRTHMLGKINEE
IRDFIDELETESLRQVDLMGARILTFKEITSKAEELVKRIEQSTSPDILE
KIQIVDKDSVINNENKRSENLYPLKNGNHTGVSDSVQQGVGHIYKENLDL
TREDAENFPNLQKVSNSKIHTSYIQKLETTSKVVKKEVVSQNKPEILPQG
STSNLVLETIGKGIRKFFGIQEIKTIRSENETSGNDFFPGTRNSTLDISL
DENPFAPISESKLNETSSLVFKDNLKPKEADFGRILQENIVGYQPIKPDS
TKISAEAALLEIGDDSTKIEKVVFLLKRKYTHEEISEVLDLALGEVDIIE
RFRLDRNRRF
>gid:3991    Cytidylate kinase
MTKLLGLRLLFLVLKSYSRVVSMNENVIALDGPAGSGKSTVARQIAEKIG
FNYLDTGAFYRALTLYLFRLYQTSPNNRFEEWVKTSEAERSLSQIRIVCE
FSAGNENRILLDGEDVSLAIRTPEITREIKHIANRRIYRDFVNKELHSLA
KLHKLIMDGRDIGTEVFPDAKFKFYLTASSKVRAERRFLQLQEQGIFADR
NEIEKEIILRDKSDMEREIAPLYQAKDAILIDTDILSKNSVISKILEILD
Q
>gid:2791    probable dCTP deaminase  dcd
MILTGKEIQKRIGNDIVITPYSEKQLNPNSYNLRLHEELLVYTELPLDMK
KPNPAEKLVIPESGLLLKPGILYLGRTLESTETHNLVPMLEGRSSIGRLG
MLVHVTAGFGDVGFKGFWTLEISVIQPLIVYPGVEVCQIFYHTLEGQITE
YTSGKYQANRGIQTSMLYKDFEK
>gid:4781    HIT family hydrolase
MCVMEDSNSTQWDEPRKNLFSIHKLDYARGKRPDVDCILCGICRKDPEVP
NLTVAETNFTIVSVNLYPYNPGHLIVFPKRHILSYEELTKEEAMEIHEGT
VKAISILKKLWNVQGFNLGYNLGKNSGGSIPHIHEHIVPRFPNEAGFLDV
LANSRIVIYEPYEMQKEWIRIWKEFS
>gid:3036    probable chlorohydrolase
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGL
YVYPGLINGHDHLLSTYLPRVAPSKPYLNWLPWDNDLKSSIVFSERQQLD
PEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFIETMPVRILNRFTLSHSI
CTYSLDWGDGPEEEYAKALKQDIPYITCIAEGFDSESRDSLKNLYQLGCL
GEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYERTTDIKDVLKH
GVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNP
AKAFRIEKQLGSIEVGKIADLTILTRNFEDPYLNLCESNLNSIRLVLRDG
LPVYGDISLKSFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYK
KDLAFFPVQKEFDNFE
>gid:3130    Predicted HD family protein
MKIQWFHYENEGYYLSVKNLNEPIESLNPLYLRITHFNQNIDKIIGFILD
RYLQYLDIGPLRECIFSILRETLMNAIKANQKRMVFKEAGLDIKDPDQYL
IGMERFKEELISKKDLYADLLEQNGLYVLITFGFNQNSFLLKVSNNVGIL
PEEDQRIQERISKARSYNDLSEVFENHGDESEGAGLGLAMSLLMLKNEGI
EGDSYRIKSEEGITSAYIKIPFEFKKRNINLQKTGDIFAELDTLPTFPDN
INQIMSLINKPDSSIQNITELVSRDVSLSTNILKLANSASFSQRARVEDL
EDAIKVIGLSELNNILLSLGTKKILEEKYNEFEAIWERSSLSAFICRRLG
ERMGWKKQTITVLVCAALLHDVGRVILLSIDPNVSAKISEILGNRLYPSP
LTLEEAALGISHTTLGGMICEKWNFSDTIRVAAEMHHRPLLVKREFQDTV
FAIYLSDMIIDISSGISDYSMIQSAVLQHFGFKKEEEFVEFMDKTLLEYK
NFP
>gid:6725    Adenosine deaminase
MKPYADLHNHLYGSITSEFLYELGKSNPSPRWEIFTSSYLQCFGKKISTE
TFFQDYQDPDSFRKFYQFNHRGPFTEFQAKFNLIIALSKFDPAEISLVAT
RVVENQFLQGVTYGEYRLMYSPLETEIGIYEKTLAACEGLALGEQKTGGL
AKGKLVISLHRDGDIFQEYLIYKNIMEKNSLIRNYLVGLDFCYIEEGFPP
KGKRKFFQEVNRDNQAEKNTALAILYHVGESFQDKSILSASRWVLESAEW
GAHRLGHAIALGLHPSEKMKDEITEPRSERLDQLQLYYDRKEELDSYFEV
PSREKIGNEIDSLKHKETVKFNISPSFLEECIGFQNYCISKIKQTNAIIE
SCPSSNEYIGMVVNPESHPILRFAKNDMKFTISTDDPGIFGTSIKEEFSK
AAKIGLSTEVLETVRRNSFLFTSEILSGKKSSSEFEVLESF
>gid:6440    hypothetical protein
MHSHFFDYVNSSQFKERTILFLGEFSIGPIYRIDTIEGQKIRQEWISKNL
SYHPKDYYAKDFFSSFLKFTEEVRSIPKENKIAIWKSKNTESYLGLCFAL
SILGDRDQIRVIDLSEANRKILQKNYEIRFAGEVSPEDLERIRKASEKNE
YLSEEMKMNLIKKWQFFSESKDILRIWKDDQVHSIPEDYYDDFIVAYAKK
IGAEKDFYTATKLIGSVLYHSANDLSESHTSCDAFFDYRIRILIKRGVFE
AQDIFKPDLKYKIKLIS
>gid:6533    Adenosine deaminase
MALTFQEILDRIRIIDRDVTELNRLKSRLPADRPYSSSLQISFDKQINEL
LNERVGLMELEVLDPPSWILGVPTTGISQETPVPLKGLFPSGDLSKEKPD
DQDVINFLRELPKTEIHLHLEACVNKDTMKRLMAKNGINVTDEEFEAKFN
FKDLNSFIQVFFFIQSLVKEPSDFSFFIESLAEYMRANNILYTEVFFAPS
KFIQNGLDFEEMIDFLVNRIREEKENDGIVIRLLVDVSRSFGPENAMKNL
DRVLKLRHPEVIGIGLGGAELMGPARDYQGVFQKAREAGLRVVAHSGEDD
GPWAIWEAVELLKAERIGHGTSAIQDPELVKYLRENHIPIEICVTSNVFT
GKYVRKEQNHPVRYYYDQGLPLSINTDDPEIFNVNLTYEYYKLWRFLDFS
LDEIVDLIRQGVFASFHPNKESLWAEMEKNIHLVKTRYGLKR
>gid:3852    hypothetical protein
MDILLLDDGQKIQSSLIEGSVGTDSLLVPGVYWNRLNLQEKKALRNKLPF
LLRKYSKQIASMKRLHNKAGKIKYNRGVGKMKKLSIRVHSGVWATLGVLA
AAHGVSRCYLFNYMLWLDEQGDFFVKTLNRGVPSFHWTYKMIWKIDRRQN
FISRELQFEPNPMTNQYPYYLKE
>gid:6925    Nucleoside diphosphate kinase
MSRTFIMIKPDGVKNKHVGNILSRIEKEGFKILGLKYLKLSLEDAKQFYK
VHSARPFYNDLCNYMSSGPIVAAALERDNAVLHWREVIGATDPKEAAAGT
IRALYAESKEANAVHGSDSDDNAALEISFFFKGNELF
>gid:3534    thymidylate kinase
MNSDKNVLLDRYMYSTAAYQSGDDLSPEMILKKNLNRNFKIPDLLFYLDL
SPSIALERLNRRKEGKERFETLAQLEKIRSAYEKILPKDTIRIDGNKNQN
QIVQECLEIFLTNIKSKS
>gid:5341    guanylate kinase
MDIDVQGAKIIKEKLPDKIVTIFILPPNEKEWEKRLRGRGTDSEENILKR
IQNGKLELERQNEFDYKIVNDNLDRALAELENIILKSESKSTTEK
>gid:6356    unknown protein
MSAKGISKDLIGTKLDHYEFDVERGKIREFCQAIGETNPIYFDVEAAKKA
GYEDTPAPPTYPTVIQFWGYPKIWQDMENMGVDTSRILHLKEKYTYLKPI
YPGRVSSQGECINVTVGKMDTMTFKTTIKNAKGETIVEQEMSIFIRKPEA
>gid:3487    adenylate kinase
MKNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEA
KRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQAEALDTL
LKNEGKSIDKAINLQVPDAELLKRLLGRAEIEGRADDNEVTIKNRLDNYN
KKTLPLLDFYATRKKLSQVNGVGSLEEVTSLIQKELA
>gid:3850    Deoxyuridine 5'-triphosphate nucleotidohydrolase
MKIFVQKLRPNAELPLLQTKQAAGYDIHACLDSKLVLEPGNVGLVPTGLS
FAIPQEFHFEIRPRSGFSTKNRILIPNSPGTIDSDYRGELMIPLLNLGDS
SFIIEHGMRIAQLLIRKTWYADWELVSEFADRTERGANGFGSTGH
>gid:4267    conserved hypothetical protein
MITSEKSIEIRDKVAKSTKKAGHLTTRQHPQFIFTLDKVSRQFVWSFLHS
HPFYNSEQVSQRYVEVKKENYYIPPELDGKLLELYLDAVDFASQSYFSYT
EALHPFIQEEYFQIYKARANYPDKWQTPIKKKCLEVARYLLPLGTFTYLY
HSVNGLTLHRYYRLMNSYDVPNEQRAVITEMINQVRAIDPLYADEMDDPV
PLEETTEYRYFDSMFGNGKREFHPETASTFVKEFDLELGERYSKLVSHSS
NGPEILAQSVRSILGIPKSILNDQDAIDLVLNPAKNRHLTSTLNESSMSP
ITRALFNVQYSFQKRISHTADSQDQRHRMVPGGRPVLMSQYAGIPDYITP
FVVQKYPELKEKYDVVHREIFEKLNRFLEAGGSPEHGTYLLPNSFPIRFY
ESGDLLNLHHKWRSRTCYNAQEEIFQASVDELTDVMKVHPQIAKWIKAPC
WIRLQGEVKPYCPEGDHYCGTQVWKRELSEYSRVI
>gid:4694    probable glutamine amidotransferase
MRSLIVRFKDCEGPGILLNSLKKRNYKITYHNAYDLRVKPLPDAHLVFDL
IVLLGGPQSVTDHSLADFFEPWLNLVRYAKSIPNCKVIGICLGSQIISKA
LGGEVKRGENGPEVGFYDVQVQEPHFLFDGISSFPAFHLHEDVFSIPEGT
KRLLKSEKYSNQMFSFEDRIFGIQCHLETTASMLSIWQKAHSDFIRSAGW
IPGPETEFLRSQMEKVGGSIFEKILDHSTGFETNHRALLSSQAMTAKSG
>gid:4921    hypothetical protein
MCYYNWIFIRSLFRFLLYKIRISKIITDFIYYLVLTMSDCTICNFHQSCD
SSEILARFGEFSVRHSEQEKKLKGYLYIEPRSHWTSYLDWSQESFLDFGK
ALEFATNWIYKNHSPVKIYTVTVSEMVPHMHFHLIPRYSDDLKGIDYIKL
SLQGKLLEDQSIRDL
>gid:6416    Xanthosine triphosphate pyrophosphatase
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKE
NALIKAKELFYLTKIPSIADDSGICVSALKDEPGVYSARFGGPELNDEGR
ALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGI
YGFGYDPIFIFPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP
>gid:5013    Deoxyguanosinetriphosphate triphosphohydrolase
MYFSRDDLLQKETETLAPYAISNANNGGRIYEEEEHSYRLPFQRDRDRIL
HSSAFKRLQYKTQVFIFSVGENYRNRMTHTLEVAGLSRTIASALGLNSLL
SESIALAHDLGHTPFGHAGQEILSGLMKDYGGFEHNKQSLRIVTSIEKKY
PNFPGLNLCRETLKGLMKHGADYDSSVILLERKENGPSLEGMIADLSDEI
AYTNHDIEDGWEMGYLHLGDLLENPFWKEVYEECKDQYKEVGEKILIRTS
IRTLTNFLVSDLIQNIAHRLEKKQIKSTEDLALLWKQDFRIASFSKEVDL
KFRELKSFLYEKLYRHEDLIRMSDYGKKIIESLFDYFLKHPEKIPDTYKE
RIEEESLYRVISDYVAGMTDRYAEKIYQSLP
>gid:3781    hypothetical protein
MNGIWDPKKLNVNCNGRDVSGMSQSDGFFKIEPVTKEYILSQVGIKGDWN
ISEIYDGRVKLSIALMGDSPENEFFFAMGEERLPCVFTIKDKSDGGMLGF
SAQGRVWERPNIEKGKEYKDKTWVFLLPDYKGVLTA
>gid:4729    hypothetical protein
MEMSNLCSEVKKDFHKLENRFDVSYSTLRNKIDVLIDSLAIRFINDVPRK
KRIPG
>gid:3024    MutT/nudix family protein
MKYCSSCGSSVTYKIPEGDNRSRHVCDQCGTIHYQNPKIIVGSIPIWENR
ILLCRRAIEPRKGFWTLPAGFLENRETVEEGAIRETKEEANAEINILGLQ
SVYSIPHISQIYMFFLANLVNGKFSVSSESEEIKLFSIEEIPWEELAFTS
VSFALRKYVDSSVKNSLHLGNTRDRKNLPKES
>gid:2951    conserved hypothetical protein
MIFISVALFAEAKPLIENLGLNILRNKTVFPIYQNENHALVISGTGKIYS
AMSVVFLLNEFKDQISDSSWILNFGVCGARKDISEIGKSFLIHKITDEGS
FKNVYPDILFHSPIPESALRTFDKPIFDDVVSELPNTLVDMEAFGFFTAS
RKFFSSDKIRVVKIVSDNLNKLEYSKIKNIPKMISFRIQNSLSDILSILS
IPVFQKNNIQLLAEETSTLLQICEVLRLSETERIQLKDWMIGYKMRTGNS
PDLGLSILKNSNGFLKPGQTKVKTRELGKKGLYALKQFYQS
>gid:7296  LB176  adenine phosphoribosyltransferase
MSIVKSKIRTIPDYPKPGILFRDITSLLLDPEGLALTIGTFVNRYQGKGI
TKVAGIEARGFLTGAPLAFQLGVGFIPIRKKGKLPSETVSEEYDLEYGKD
VIEVHKDSIQPGDKILLMDDLIATGGTMIAAVKLLKKLGAEIYEAGVIID
LPDLGGRKKLQEELKVPVFSICEFEGH
>gid:3971  carA  Carbamoyl-phosphate synthase small chain
MMKAFLVLDNGTIFEGESFGYETESVGEIVFNTSMAGYQEILTDPSYCNQ
IITLTYPMIGNYGIHPDNMESSKIQASGLIVKEYVDLPSNFKSEKTLSQF
LKEYKIPAIQGIDTRKLTRFIRTNGSPNGGIFVASEYSPSFLEKVKSFPG
IINADLAKVVTTSSKYIFGTHTGKKFKLAVYDYGVKTNILRLLDANGFAV
TVYPAKTPSEEIMKEGTDAFFLSNGPGDPAPLDYAIASTQKIMEKRYPLF
GICLGHQIIGLSLGKKTEKMKFGHRGGNQPVKNLETGQVEITSQNHGFAV
IDDQKQDEPISFLNLNDHTVEGILKSGYPLLTVQYHPESAPGPNDSRYLF
QKFYDLVEKTKKG
>gid:3454  carB  carbamoyl-phosphate synthase, large subunit
MPRREDIRSVLILGSGPIVIGQACEFDYSGTQAAKALKEKGIRVILLNSN
PATIMTDPDLADATYVEPMTVPVVQKILEKEKPDAILPTVGGQTALNLAL
ACNSAGILEKYNVELIGAKVDAIKKAEDRELFKKAMEKIGVRVPASGLAN
NLKDAVEIKNKLGLPLIVRPAFTLGGTGGGIAYTEETFEEVVSKGLKASP
ISQVLLEESVLGWKEFELEVMRDLADNVVIICSIENIDPMGVHTGDSITV
APQQTLSDKEYQNLRDMSIAIIREIGVETGGSNIQFAVNPTNGDVIVIEM
NPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIKNDITRVTPASFEPS
IDYVVTKVPRFAFEKFPGTDDTLGVQMKAVGEAMAIGRTFKESFQKALRS
LEIDRYGFGSDGYFQELLYSRSLNNDQRKEWIDSHLKRPNDKRIFYVKLA
FDEGYTVDQIHDLCKIDRWFLWQMEGLLKLEKEYSEKGNSILYKMKQVGF
SNRQLSFLKNKKQILDLLDGNLRVDLKKTEIQNLLKLSEEEIEVELGSKK
ILPVYKRIDTCAGEFEAYTPYFYSSYDEEDESDVTNAKSVMILGGGPNRI
GQGIEFDYCCCQASYALQDLGIESIMINSNPETVSTDYDTSDRLYFEPLT
LEDVYRIYQNEKPEGVIIQFGGQTPLKLAKDLEKKGVKILGTSPDSIDRA
EDRKRFVEVLEKLKLNSPESGIATSMEEAREIAHKIGYPVLVRPSYVLGG
RAMLIINEEKELDRYMEKAEEISKDRPLLIDSFLEDAIEVDVDALCDGKE
VFVTGIMEHIEEAGIHSGDSACVLPPQTLSKNMMDEIRKATVNLALELQV
KGLINIQYAVKNEILYIIEVNPRASRTVPFVSKALGHPIVKYATRIMMGE
SLKSLPLPKEMEFSQVSVKEVVLPFNKFPGVDTILGPEMRSTGEVMGIAS
TAGEAFLKSQYMAGDELPSQGTVFVSINDKTKAELLSYIKDLSELGFNLI
ATSGTHKFLSDNGILSSKINKVYDGIFPTALDYIRENKIHLIINTPLSRV
TRDDSFTIRQAAIRFKVPCLTTSNAAKALIKGMVEMKNKGFTIHSLQEIH
AMPKIL
>gid:7088  codA  cytosine deaminase
MSKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIR
TDNKILSDFLNKLENLVTRDREEIPSFTRIYHKEKLISETFNEVEKKSDS
SFHSEILCIRNAKEKLKTRYLADCMLITSLEPCLMCAGTILLSRIPKVVY
LLPAKQGEGISSLSIEMIYSRNFFPELFCIPTEISKNAFKSFFKVRRKKF
N
>gid:5100  nrdA  Ribonucleoside-diphosphate reductase alpha chain
MLWSKKKFMKMNRHFTVPQNGESSTIQWTKRNSKITNPDGSKVFEANDIL
VPEDWSQVAVDILAQKYFRRKGVPKYLKKVQEDGIPEWLQKSIPDTEKLE
SLKPEDRFGGETSALEVFHRLAGCWTYWGYKYKYFSDEESAKIFYDEIVY
MLATQMAAPNSPQWFNTGLNWAYGIDGKSQGHYYVDPSTGKLVKSTSAYE
HPQPHACFIQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRGEN
EPLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIEN
FIDWKVTEEKKVASLVTGSMLNNRHLNAIMSACYEMEGEDRFNPKKNSSL
KKTIQDAKKVLIPDNYIKRVIDLARQGYKEILFEELTTDWQSDAYNTVSG
QNSNNSIRLTNEFMAAVEQDQPWNLYFRTEKEKAKVEGRKAKPSQTLRAR
ELWEKISYAAWASADPGTQYHTTINEWHTCPEDGPINASNPCSEYMFLDN
TACNLASANLQKFVNLETLNFDVEGFRYLCKLWTIILEISVTMAQFPSKE
IAELSYKFRTLGLGYANLGSVLMVLGIPYDSQQAMAITGAISSIMHMTAY
ATSAEMAKEQGPFVGYAKNQKHMLRVIRNHRRAAYNAPSGDYEGLTITPI
GINPAFCPSYMLKAAQEDADLALSLGEKYGFRNAQVTVIAPTGTIGLVMD
CDTTGIEPDFTLVKFKKLAGGGYFKIINQSVPYGLKKLGYSPSEIEAIVN
YCKGHATLNGAPVINTQALKEKGFTNEILEKVEASLPLAFDINFAFNKFN
LGENFLTKNLGISKEIFDSPGFSLLEHLGFTKEDINKANDYVCGTMTIEN
APFLKEKDYPVFDCANKCGKYGKRFLSYESHIRIMAAAQPFISGAISKTI
NLPEEAVIEDIKNAYFLSWKMMIKANALYRDGSKLSQPLNSVLELLNGIE
IDDQEEIREATISKDPVQIAEKIVTKYISHRRKLPSRRAGYTQKAIVGGH
KVYLRTGEYEDGQIGEIFIDMHKEGAAFRSLMNAFAISVSLGLQHGVPLE
EYVDAFTFFKFEPNGIVSGNKHIKMSTSVIDYIFRELAITYLGRYDLGQV
APEDLRGDEIGSKRATAESNGQEKETLSSMTAVIEPTPKKEVETISYSQM
ISKEKPSSSPSGISLLEEVKLAKIKGYTGDSCSECGSFEMVRNGSCLKCM
SCGSTTGCS
>gid:6573  prsA  Ribose-phosphate pyrophosphokinase
MNGDIAVFAGNSNKQIAEEICTHLGIQSGKINLKKFSDGEISVKIEDNVR
GKEVFIVQSTSAPANDHLMELILIMDALRRASVSSISVVIPYYGYGRQDR
KVEPRVPISARVVADLIEVVGLDRILTMDLHADQIQGFFRVPVDNLHFAP
VLAEYVNTKKIDDLVIVSPDSGGAERARAFGKKVNGSLAIIDKRRPKANV
SEVMNVIGEIEGKNCILLDDMIDTAGTICKAADALLKHGAKSVYCAATHG
VLSGEAVDRINSTQFSEVVLANTIAIPESKKINKLKSLSVAPLFANAIQR
IHTNQSVSTLFD
>gid:3841  purA  adenylosuccinate synthetase
MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKY
VFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECDRLQKEGFPVFDKLLLS
DACHLLFPYHSQIDSARETTLSQEHKIGTTKKGIGICYADKMMRTGLRVG
DLLDTSYQTRLKHLVDEKNRELDKLYGMPPVSYNDINEGLKFFLSKVKKN
IINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNPTTGGALI
GTGIPFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEKLRQKGGEFGAT
TGRPRRCGWFDVEMLKHSVRINGITSIALTKIDILSDYDTIPVATGYKLN
GKTLDCFPSQGLDKVEVIYEEFPGWKSDISGICEFQKLPEKCKNYISALE
KWIGVKINLVSTGPDRKDTIHGDSF
>gid:5823  purB  adenylosuccinate lyase
MIDRYSNPEISKIWELENKFEIWKEIEILACEIRMKRGEVPQEDFQEIKS
KAKFNVDEILEIESKVHHDVIAFLTNMNSYIGPAGRHVHYGLTSSDIGDT
ALCVQMVQAMDLILKKTDSLIEVVREKAIQYKNLPCIGRSHGIHAEPMTL
GLKFALFFEELNRNRKRMAEARNEIAVGKLSGAVGTYSNIDPEIETYVCE
KMGLRVDPIATQVVSRDRHAFYLSVLGVTASSLDRMATEIRLLQKTEGRE
VEEPFSAGQKGSSAMPHKRNPVICERISGLSRVIRANVNVGLQDVALWHE
RDISHSSAERVVLPDSTIALEYILDKMLFVIKNLHVYPDAIERTLGVTRG
LVFSQKVLLALIEKGKIIREEAYLIVQEHAMAVWASQSETLKSRLEKDDR
VSKVLTQKDLDDIFKIEPYLEKVGLIYKRLGLE
>gid:6263  purC  Phosphoribosylaminoimidazole-succinocarboxamidesynthase
MNPSYKGKVRDIYDLGDKLILSSSDRISAFDVVFPQLVPDKGKVLNRISV
SWFEFFKDVPNHILETDVKYFPIPFQNHPDLEGRSVLVKKCKRIDYECVV
RGYISGSGWKEYKNDGTLAGIKLPSGFKESQKLPEPVFTPAVKNDQGHDE
NISEKEMENRIGKELFNILKEKSISIFLRASEVVDKAGIILCDTKFEFGI
LDGQVILIDELLTPDSSRYWSTDTYSVGISPPSLDKQILRNYLETTSWNK
MPPAPNLPAELIQELREKYQKIEDLILSCTSQKSK
>gid:6514  purD  Phosphoribosylamine--glycine ligase
MQVKLKVLLIGSGGRESAIAFYLRKSVLLSELKVFPGNGGFPDQELLPPD
SFQVLDKNSVQSFLKQNPFDLIVVGPEDPLVAGFADWAAELNIPVFGPDS
FCAQVEGSKDFAKSLMTEAKIPTAEYKTFSEYSDSLKYLESKSIPIVIKA
DGLAAGKGVTVATSKEMAQTALKEIFKDKKFGSSGNQVVIEEFMEGQEAS
IFAISDGDSYFLLPAAQDHKRAFDGDQGPNTGGMGAYCPAPVISESILQK
VKEQIFDPMFDLFRKKGHPYRGLLYAGLMISPNGEPKVVEFNCRFGDPET
QCVLAMLDGDLLELLYRASTGKIKGVQAAVKKGAAVVVVLAAQGYPDFYE
KNIPLNLPETSGQNVHLFHAGTLKKDGKVFSSGGRILGIVAQGADLKSSV
DQAYSFLEKIQAPKTFYRKDIGYRAL
>gid:4196  purE  Phosphoribosylaminoimidazole carboxylase catalytic subunit
MNTKVAIIMGSHSDWETMKEAEIILKEFGVSIHKEIVSAHRSPELMLEFS
KSAKEKGYSVIIAGAGGAAHLPGMVASMTTLPVLGVPIQSKTLNGLDSLL
SIVQMPGGVPVGTLAIGTAGAKNAGLLAVRILALQDPILSEKLERYRNQI
REDALSKNKDLL
>gid:6848  purF  Amidophosphoribosyltransferase
MSRIPDKSRIRRQAQDDKPKEECAIFGIFNSSEASNFTYLGLYSMQHRGQ
ESSGIVSSDGEHLYRYAGMGLVAHIFTETKLKELQGNAAIGHNRYSTTGA
SFLRNAQPLRVESHLGAVSLAHNGNLVNSWELRSQLEKEGSIFQTTIDSE
VIVHLMARSGETDFLSALSSALKKVRGAYSLVILTKTQLIAVRDPNGFRP
LVMGRREDGSIVFASETCAFDITDTKYERDVEPGEMIVVDKNGMNSYYPF
PKASPSLCIFEYIYFARPDSSIFGESVYKVRKNLGRFLARELPVPADVVI
PVPDSANIAALGYAEESGISYQSGLIRSHYIGRTFIEPDQKIRDFGAKIK
YNVVRNVVEGKRVIVVDDSIMRGTTSRKIIKMIRNAGAKEIHLRVSAPPT
ISPCYYGIDIPTHNELIAATHTIEEIRKYLRVDSIAYLSVESMNRAVMDH
KGGGFCNACFTAQYPVEFQSELGNQKSLFKEYQVEERVVY
>gid:5022  purH  IMP cyclohydrolase
MIQIKRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIA
IDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLV
VVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPN
DYKKIQNLISSSGISEEISASYMRKAFSHTAMYDAAISSWFYKQSGEVFP
DVLNLSFIKKQKLRYGENPHQAASFYEPLFTKSDFSPLQGKELSFNNMLD
FDAAFHISSLLPENTVCIIKHLNPCGIAYADNPLEAFQLARRTDPISAFG
GVIGIKGQVNGELATSITENFVEGVIAQKFTQEALEVFSKKPNIRLIEIQ
DFKEALDELDLRPIHHGLLIQDRDYTTITEKDLKVVTKKQPSPDDIRGLM
FAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGANKALNVGLSV
VGSYVASDAFFPFRDGIDALAKAGAKAIIQPGGSVRDEEVIQAADEHGLI
MVFTGMRHFRH
>gid:4195  purK  Phosphoribosylaminoimidazole carboxylase ATPase subunit
MNNSRMLLPGSRLGVMGSGQLARMFCLEAIPFGYEISVYSPEKNSPAAGA
GAKEYISTYEDEKALTFFLENIDGLTFEFENIPEIALTTIENFSKRTGLI
VRPSPNCVRISQNRWKEKTSFQKAGIPTVKFYPVLTEEDKKSVLSKTNFP
CILKTNTMGYDGRGQIRCITEQELSLVFSNLNKPDHIVEEFFQFTSEASV
IMARFEDGKILNFRPSKNVHKNHILDLTFYPGNFPDSIETKLVNYAKKLA
ETIDYVGVFGIEFFIRGDEILCNEFAPRPHNSGHFSQNSGTISQFSLQLR
TLCNLPSPKTILANPVSMKNILGEDYKPGSTLWNKTLENPYYHLHLYGKT
EIRNGRKMGHWNYSGPNIESAFLNWD
>gid:4056  purL  Phosphoribosylformylglycinamidine synthase II
MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSY
KNSILKLKTLPTTSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAV
EPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPKNKYLLSRAVK
GIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGIVRHDQMASATTGG
QIGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLL
MEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRE
TGMNAYEAMLSESQERMLVVPKKGKESELVSIFEKWNLNAVKIGEVTADG
MIEIYMGGKLKAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIP
DVTKGANSKEILLKILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLS
AIPGTNKALATATDCNSRYTYLDPYKGAEFAVCEAARNVYVTGATPYGVT
NNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGP
IFPTPTIGMVGILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKI
HGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSLGGIAVALSKT
VLFSGLGIESDLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEA
YGLKFYPIGKTNSSGILEIKDAEIKISFQELSGPYEKGLEAVFAL
>gid:5678  purM  Phosphoribosylformylglycinamidine cyclo-ligase
MPDFQVSPVFFCVQGISIFSIYSKKESGLIGMEEKITYKNAGVDTEKGRE
FIQKIKRNVESTHGPRVIGGLGGFAGAYDVSVLKKYKHPILLSGTDGVGT
KIELARLLKIYNTIGIDLVAMCVNDILVCGGEPLFFLDYIACGKLDPEKM
DQIVSGIVQGCKMSNASLLGGETAEHPGTMKEDEFDLAGFVVGAVEKDSM
IDGSTIRSGDKILGLESSGPHSNGFSLIRKLLLKEGKYLPTDPQQVKFLK
DYALKPTRIYVSSILKLLQQVSVKGMVHITGGGYQENVPRILPQGTQSKF
FKEKIPSGYFFEKIKKDHKIEELELFATFNMGIGYMVIVSEENAELAKKI
MESSGEVVHEIGEIVSGNKEEVQFV
>gid:5021  purN  Phosphoribosylglycinamide formyltransferase
MATLFTKPKKKIVFLASGRGSNLRAVLQNIKVGKIRGIAQTLICDHPDAK
ALEVAQEFELTSQVLNFSSFSNKSEYHTKLLQLLLEIKPDLIVTAGYMRI
LKSPIIQTFSNRIINIHPSLLPAFPGLNAQKQALEYGVKIAGCTAHFVDE
GIDSGPIILQGVVKIEEGMTERDLTLEILKEEHKILPLAVQYFCEDRLTI
QNRKVKIG
>gid:6261  purQ  phosphoribosylformyl glycinamidine synthetase
MKIAVITFPGSNCDSDIYRVLKDQYNAEVDRIWHRDGLDKKYELVILPGG
FSYGDYLRSGAMAGFSPVMKSVKEHVDKGGKLFGICNGFQILTEAEYLPG
ALIRNKTLKYICKTVILTKGSAGNPVTASMDVRKELKIPIAHADGCYYAT
SDVLKQLEDEDRILFRYSGENPNGSLDSIAGITSKNFKIVGMMPHPERAM
NPITGEMDGKVVLDLILGS
>gid:7023  purT  Phosphoribosylglycinamide formyltransferase 2
MKKKILLLGSGELGKEFVIAAQRLGQYVIAVDSYDDAPAMQVAHEKEIIN
MLDGNLLDQIIAKHKPDLIVPEIEAIKTERFYEYEKQGYQVVPSAKAANF
TMNRKSIRDLAAKDLKLLTAKYAYASSIDELIKATEILGFPCVVKPLMSS
SGKGQSVIQSREEISKAWEASQTKGRAGAAEIIVEEFIPFESEITLLTVT
QKNGKTLFCPPIGHRQERGDYQESWQPAAISEVQLKEAQRMADAVTKELT
GFGIWGVEFFLTEDKVYFSELSPRPHDTGMVTLAGTQNFNEFELHLRAIL
GIPILEITLERKGASAVILASTENKTPEISGLDIASGMSESDFRIFGKPI
TRPYRRMGVTLSYSTKGEEISSLRKRAVLLASKIKVD
>gid:3505  pyrB  Aspartate carbamoyltransferase
MSKGSFFTFCRLMYYNHKNVLDTEQFSKPDLDFLIGKIRVMERLVEQNKA
FGILTGKLLASLFFEASTRTRLSFEAAMERLGGRVISTVGFQFSSISKGE
TLYDTMKMVEAYADIAVIRHPVEGSSRIAAGAVKIPVINAGDGAGQHPTQ
AILDLYTIISEKGTLDGLTVAFIGDLKYGRTIHSLINLLRHYKVRLFLIS
PPELALPESYKKALQGYSLTLEETTDIKAVWDCDVAYVTRIQEERFPDHK
EYERLKDLFKINKELILASKKETTVLHPLPRVNELSTDVDDLPNAAYFRQ
ARYGVVSRMTLLCLSLGQDF
>gid:6386  pyrC  Dihydroorotase
MIKKISGRIVTHEKDFLGTVEWDSKTGLILTVLEQKESIPILNSQHQENE
IQFNSLETVIFPGFGDIHIHAREDESGKHTYKEDFVSASAAAVNGGVIHV
ADMPNNPIPPIDENSYSKKRKLADRSNIHITLYAGIGPDTKPLKKSVPYK
VFMGPSIGELFFHNNQTLEDTISSYVGENVSFHCEDPEILEKHQNETFHE
DRRPAEAETTATDFALYLIEKYNLRGKLCHYSTGEGLNKIKFAKQKGVKV
TCEVTPTHLFFDRSMLTPENRHWFQMNPPLRSKEDRERMLEGVKQGWIDY
LATDHAPHSIEEKRKGTSGISQLDTYSLFVTWLVLKAGVELKTVARICAK
NPGDFVNEYLPEKFGKGFGRIEPGYSANFTVLNLKKPKKFLKEEIKSKSG
WSPFENFEFPGSIEAVFFLGKQMK
>gid:7047  pyrD  Dihydroorotate dehydrogenase
MINRNKIVLEMFLPHLRQSAYSVFLKPFFLSLDPETAHELAKNFLGIGQK
FPGFLTLMESMTSYQSDRLKTKIAGIEFENPLGMGAGFDKTGELYPFLSR
MGFGHIEVGTITGQKQSGNPKPRVFRYPQDQALVNRMGFNNPGADSAEKI
ISSQKKTKIRGINAGKTKIVPEEKAVEDYVYTLKKLSPYADYAVINISSP
NTPGLRNFQKQENFVSLIQGIRKDLGKNFKIPLFVKFAPDMETKELEALL
ETSLSLKINGVVLTNTTIDKSCLKNYPNVEKEGGLSGTPLKNRSTEFVRI
AYRILKRRIPIIGVGGIDSEKTALEKILAGADLIQIYTGYIYQGPFLPMR
ILKFLDRFLEKQDLKTVSDLVGKEKEIRLDQK
>gid:5731  pyrE  Orotate phosphoribosyltransferase 1
MLKKELSMKQELLELIRTHVYRYSEQPFTLASGRKSRHYFNCKEITLVPD
RLELLCKFIVEQHLGESGILLPHAFGGLTMGADPICYGISLEFRKQNKNV
YPLIVRKLSKDHGTKKLVEGSTHLVKQCVVIDDVITTGGSTIQAIRSLRD
CGIEVVQGVCILDRQEGGKDAILAEGVEMFPIFKKSDFGNLEHE
>gid:7430  pyrF  orotidine-5'-monophosphate decarboxylase
MGGKMNFQSKFLTRSQSLKSLLCVGLDPDFDKLPEIVKRSPEPLVQFCKE
IIDATASYAVAYKPNIAFFEVFGSSGIRQFEKVIGHLKSNYPQIPIVADV
KRGDLDNTARQYAKYYFGDLQVDSLTLSPYMGLDSIRPFLEYQDYLIFWL
CLTSNPDSAQFQKKRFSETGRTLYEEVVYVANLVAISNLGFVVGATSPSE
LETLRTQNPNRIFLIPGFGAQGAKLENLLPVCGRNSLINSSRGIHFASNG
SDFAVRAGQEAEKIHKMMQTHFIGL
>gid:5149  pyrG  CTP synthase
MEYTLSRTKFIFVTGGVSSSLGKGVTVAALGCLLESRGYTVSLQKMDPYI
NIDPGTMSPYQHGEVYVTADGAETDLDLGYYERFTHSKLTRKNSVSTGQI
YNTVIQRERKGDYLGRTVQVVPHITNEIRNRMYIVAREENPDFIIVEIGG
TVGDIESIPFLEAIRQMRYEHGSSNVLFVHLTLVPTITAAGEAKTKPTQH
SVKELLGLGIQPDILVCRVSQPMTKEMKNKLSLFCNVKEENVISASDIST
SIYEIPKMYKEEKLDEVVLKTMGMELRESNFSEWDKMVKGLLTTKQTVQI
AVVGKYISLQDAYRSIYESLSHGGIAHDTKVEFIKVDPENLNKDSYVEIL
KKVHGILVPGGFGDRGIEGKILAIQYARTNGIPFLGICLGMQCAVVEYGR
NVLGLKDANSTEIRPDTEHPVISLLEEQNDIEQMGGTMRLGSYPCKVKEN
TLSYSEYKSILIHERHRHRFEFTNRYRKQYEENGMIIAGTSPDDNLVEIV
EIPKHNWFIGVQFHPEFQSKPTLPHPLFAGFIRASVKYSKKG
>gid:6042  pyrH  uridylate kinase
MATEAKYNRILIKLSGEALAGEGEFGIDTNKAHSLAEEIKEVHDLGVEIA
LVVGGGNIIRGTNLAKAGIDRATADYMGMLATIQNALALQDACEKKGLYT
RVQSAIEINSIAESYIRRRAVRHLEKRRIVIFAGGTGNPYFTTDTTASLR
AVEVGCDVILKATKVDGVYTADPKKDNGAKRYSQISFMESINRRLKVMDS
TALSLCMENNMSIIVFDIFKRGNLKDLVTGKNIGTLISNSEDIQIDGK


# Treponema denticola ATCC 35405

>TDE0439 hypothetical protein
MKKMIIVFFCMLFISVNSFAEFVISPTLGASNVFSTDVFPPTVYIGGLSH
KEKSSLSWTPMNFGILLGTVKEKGFTFLFSVDALFIGNVNANYKEFVRDT
EVLNFKAKAKIGGGAVAQGNFLFGYTYKGVPNLYLTFASGLTLGGGVNTI
KEISTSGITVPNINVSLKTANFGIPLYFSASYYFTDKIGINVSFLNSFCA
GWQWYNDKSPLPYLGTGYGPETPAFVNVFTFKIGPTFKL
>TDE0687 phosphoribosylaminoimidazole carboxylase, PurE protein
MRPLVIILMGSSSDMGHAEKIASELKTFGIEYAIRIGSAHKTAEHVVSML
KEYEALDRPKLYITIAGRSNALSGFVDGFVKGATIACPPPSDSFAGADIY
SSLRMPSGISPALVLEPKNAALLAARIFSLYDKEIADSVKSYMESNAQKI
IEDDSKLKR
>TDE0009 hypothetical protein
MAIITISRKIASFGDETAIELAKLLNYNFIDRKSLEKDLLAKGISEVQLK
KYDERKPGFWASLSRERDSYFDYLREAVYEHASSGNSIFIGRGGFAILRN
VPGLYSVRLVAADDIRISRLMKEFNYSEKEARALMEESDNNRDGFHKNFF
NTVNEDSSEYNLVINTGHISHLQAAEIIKYGLEKTISKEDAALGDKRLKE
LLLAQKIVNHISFDLKLQIYFLEADISEHEIILHGVADNAGLIQKAIDVA
QEMAGGRKVSSAISMVNEYKPFP
>TDE0594 cysteine protease domain, YopT-type
MKKFLMITITVCLLAGGVNAFAYGINSFTVYDAQDNIVHKITAKSKVNAL
YLLFQESLQIAADEAFFMELPKDAQVLYRYVLSYNYGDDEQYFSFIVYKN
YPLCRIPQLQEKEDIPKELTWKLFKYAYEIASRPAEVKKQLSYSAKNSYI
RIYDDKGSLLLFTAGEKILDMFDTLFGKDIAEIEIEERNLKSLFTAESIH
DGREVLVHYSFMDDDKIMKLYIYKDTKEMNITTDTGVLKVNLSEEAYRIL
SSPKSFQKEFEKRR
>TDE2085 amino acid kinase family protein
MVTVLSVGGSIVAPDKPDFDFLDKFSKTIRNWLLQDSSRKIIMVIGGGAP
ARDYQNAYRKVCDLRKAPAKNDEADWIGIMATRLNAQLVKAVFEDLCPNP
VVYDPTTVDMFGGQILVAAGWKPGFSTDNDAVVLAERFSGNLVVNLSNIA
KVYTDDPKKNPEARPIDSISWEDFIKIVGTEWVPGKNTPFDPIASQRAQK
AGIKVICAAGKDIENLENILNGKDFKGTVIG
>TDE1612 phosphoribosyl transferase domain protein
MGKVIMGAEALDGYLTEDDLRHLNEMNALYQEAIENFAVLEKENGEKKKK
AKDEVIRLYTEMGHLMQNICKDIPQLKVFSFDTEHENHAEASRVIAKLRS
IKTEHSEFLYYTQRSFEMLFKLAYKGHQKDKKNYLVVKTPVTNPVQNYAV
HKITDIDHKIENTVMCVMLRGALLPSMILSKEIEEYSSHGYVTPFALFKI
KRDDSRKEDDMQYILDLDKSYFNLKDLDGKDLIFADPMNATGGSLVTVVK
HLKKLGVKPKSISCFHVISALKGALRIVRALDNCTLYTLWMDPALNASAY
IMPGLGDAGDRINGTDTDETPRNIIQLLADYGSNIAGLYRSQLRQIEKTV
LGN
>TDE2107 dihydroorotase, putative
MIDSHVHLRDGLLSDKETIAHALALACPAGFTAFFDMPNTNPPLTNAEAV
LERFALAEKSIKQAGVSAFYGIYGGLTSDIAQIEKMVLFYKKYFPKIVGF
KMFAGHSTGNMGIVEKEDQRKVYAALKKFDYRGILAVHCEKESLMNNSIF
DIENPITHSLARPPIAETESIKDQIELMQSEDFKGHLHVCHISTKEGIRL
VAEAKKSGLSISCGATAHHALLNIDSYKKSGIFVKMNPPLREKEEQEAVF
NALISGGIDWIESDHAPHTYEDKKKGASGIPGFAGSLILLKELRKAGCSE
KRLDELCGKAVNHIFKLDLSYKVPSNTEIDASLPSLRSGYPFDAFEFFGI
SKFSFLNFIVTLTICTIAYIL
>TDE1803 conserved hypothetical protein
MENYENRIVAFIDILGFKDLIKKSENNPYQINELLEILKYIKAWDTQGQN
KWDTNVIAVEEDAQTKGLEKFDISGITACTCFSDSIVVSVQCENELINEK
ASTLIGNLSKIGAKLLQAGILIRGAMTVGNLIHTNDGIIMGPAIIEAYLL
ESNYAKNPRIILSDKLIGKLNYPLKRKSDRYPYHQYINRFKDGCAGFHQM
QFFQVMQSEVNEQNKLKYDLDVIRKRLIDGLDMSFSKPEVFLKYQWLMNQ
YNELVINEDNVKKPIYDVNLADSHLNIHYSPIDQVRNKEDT
>TDE2257 5'-nucleotidase family protein
MKNSKFFKAVGFVVIVLILAAAFTGCETESHDVSGQYAGIEANAPANRID
ILLFNDFHGNVAEDTRPGKGKNAGMAKMIGYVRTAGMENPNTIVVAGGDN
YQGTAISNLTYGAPVSAMMRAMDVKVCAVGNHEFDWGSNRMTKWQKDGNF
TFLAANIVEKKTGKPVSWAKPYAIIKKGNYKIAFIGLAHPDTAVLTSAEH
VSGLEFTDPVKTGQEWVNYLLAGKAKEGKPDAIIALTHIDSFQEDGKISG
NAVKLTEIKGLDAVLSAHSHRTVSGNVNGIPILQAYCYGRAVGKLSITFG
SENKIAKIESAVDEIYKHKDSLIEDEKGKALFTKYDTELKPIMGEVIGVA
EGEFTHERSEKGSNTLLGAWAAEVQRQLGKADIAIQNGGGLRRTLAAGNI
TVGDLYEIMPFDNYLVVFDLPGSEIKKAIDHGIMNPNITDGQFAGLRVEY
DGRKPFENRITKITLMDGTPLDMNKKYRVVVNSFMFTGGDSYDFSKATNS
AESVSIRDALIDAIKKAKTIKPIPVDYIKDISK
>TDE0188 adenosine/AMP deaminase family protein
MRDFDYYKKQPKADTHNHLNLSMEYSDYKKWAGFEIPNFPRKMNGLDEMH
EIIGQYTRPACTTAQHVIDLIEMSIMTAIKDNVVCIEGSVDIGFIKQFNE
NLDAFLEGISGIVKKYKNKIKIIPELGISKTIDQSFLKQWIEPMISSKVF
KNIDLYGPEVSEGIEQCVYIFKLAEKYGLKKKAHVGEFSDAASVKYFVEM
FNLDEVQHGIGAAQNDKVLQFLADRKIRCNVCPQSNIMLGAAKDLKSHPL
RKMMDAGVPISIGTDDILFFGKTNSEQFYDLVSEKVITEEEADQLMAIR
>TDE0015 lipoprotein, putative
MKFRRYIFILIPMIFIGFTACNNRPIFAAIEQEVELKEFSVGGNVLSLVA
TDTMVYASNLAGVYSKSKNYDGPWSKILPAERTQKLAKNAANVFASFVTG
PVKFYDESTKTWSAVSGSDDIHVIAGDTTVFGYDSNQKKVFKIGIAGINN
PIATGEVNFLYAAGNYVVVQSKNSAKLYKADASPAVEISNLPSGVKGMCS
TGNPNEVFVLAGSTVYYINGGTWNNKISISKSPVSISYFKERKTILLGCD
KGYTEIQLDNAHTTDLSKAKQLNPGNSGSTTPPGSYSQYQTTLGSYYTYP
VLGVERGNAGSGKYAVFMGIYSGTITRNTGLWGFYSDKKREWNRE
>TDE0423 hypothetical protein
MKKDKLKLIFILILAALLFSCSKELKEQKPEETKVESSAKIEPKENEFLS
KPEYNTHVKSPEQIKELEEKYKRSEAYEEKLKQLRTELDKKEDILRYKCP
VFMSIDNLAQQKAPALYSHADNLDFIHFYEIKKDGEFCYCKYKAPTQNGG
ILDYQVTYKWYNIEQMYLPLSYDLLSETNMVKINDELIENQVHGSIYSME
NDEKKDEMIKLFEDYENTQYPLYLEVANTDWKTGAKTEGYKQYDMKILDY
VKGNFTNSGYDEYFVMFYRDHPNPEIDDQFIERVRCFIVSEDKIINDYYI
SNSGGFFYPGLRYDKLSEVKDFGFKFSQGWIADFNQNGINEIYLAALFDI
YGGGLLIIEYNDGSFVSGYVYDNRYDIVGIDWYKKMIIIKDKSRSGEWID
DYQWNDTLKEFILLKRKYRDD
>TDE0311 thymidylate synthase-complementing family protein
MDKEFKVLDKGFIRLVDYMGTDARIVQSARVSYGEGTKTVREDAALIDYL
LRNKHTSPFEQVVFTFHVKLPIFVARQWIRHRTARLNEISGRYSILKAEF
YVPAGKDIALQSSDNKQGRMNEAVPQDLQNEVITSLQKQQEEIYAGYSKL
LDKNIARELARINLPLSTYTEWYWQIDLHNLFHFLRLRMDAHAQKEIRDY
AEVMFEICKTVTPLACASFERHEKNGVNFSAEELEAIRNLIAGKDSGLKG
KELERFNEKLKSGRQV
>TDE0901 conserved hypothetical protein
MCLICKRIEMIKNGNNPYYVKELETGYVVIGDHQHFKGYTLFLCKEHKTE
IFQLENDFKMKFLEEMSIIAEAVYKAFHAEKMNYELLGNGDTHLHWHLFP
RINGDLEGHGLHGKGPVWWYPIDKMYDAANRPTSEELYDMKVKLLEHLKK
A
>TDE1499 adenylosuccinate lyase, putative
METRSIFKNISPIDHRYSLPQGGLYDELSVFLSEEAGIVYCAMAEMAIVK
AHLKIAEEKKGSLLPKLSGELEKTLDDIALNIDPSEVYEEEHKTQHNIRA
LVNVLKKKVPENTAPLVHLGATSADILDTAFSMRIRDAVIKVIIPLLKKT
ELLLCDIAEREAETPQVGRTHGQHAVPITFGYAVSEYVARLGKSILKMED
LVKDLRGKFAGAVGAYNAASLIVSDPMRFEKIYLDYLGLKPSEYSHQLVE
PEYMLRLLLEANIAFGIIANLADDLRNLQRTEIGEVFEYFSATQVGSSTM
PQKRNPWNSEHVKSLWKAFSPRIMSFYMDQISEHQRDLSNSASQRFIADY
LTGLALAFNRMNSILKGLQADRENMLKNLLQGGGKVRGGVMAEPAYILLA
ECGVSDAHEVIRKITLAAENQKISFYEALKAEEKVFALVTERLKELNFDK
PEEFFANPERYRGLANVKAKALAEKYKALM
>TDE0267 HAM1 protein
MDLRFVTKNKFKVDEVQKLLTSINVIHCPIEIKEIQTESIDEIVNDKVLK
AFNKIGRPLFIEHTSLYLGGMNGFPGGLTQIFWDKLQADKFSEIVSKMSD
QTVEAKTVIGYCTGKKIYKFEGVIKGKISDLPKGSKDFQWDCVFIPDGHS
QTFAEMGEQKNIISMRKIAFDKFYDFLKDKR
>TDE2271 HAM1 protein
MKIYLASGNVNKKREVQELLPSHTIVLPKDEGIEFDPEETGSTFFENAMI
KAKALYHIVKAPVLADDSGLCVDFLNGAPGIHSARYGSIEGEHVSAEAGI
NKVLSELKGVKDRSARFACCMVCLLDENRFYSVQETCEGHITEAPSGSGG
FGYDPIFFVEKFGKTFAELTSEQKNSISHRGRALFSISRFIKGS
>TDE0202 conserved domain protein
MKTSRIKFAVRLMFFLFCVSAVFSESGDIKQNIPVTSMPPKWEPLFPSAL
WVKNIPIKQEVLIQTVKTKEEMDASLKFDESKLQSVLLNNDIFALYGKPG
AYTMGILGRYSPEEIEPIMNEFIITYDEVNKERGIIPAFYLIYGTCWPEG
EIGLLRLSTVKKYIEFAAERGWYVFIDHQIGKYTVEQAMNAILPFLKYPN
VHLALDPEWRTTQPMRVIGSVTGDEINKAQEMMDKYIKENNITGRRMLVI
HQFNSIMIKKRANVRSDYERVQLIHCADGFGSPQLKKDSYAYNALAQNIP
LKSFKLFSKPTVAGAGYDQPMMTPDEVFNLNPRPYLIMYQ
>TDE0105 MTA/SAH nucleosidase
MKIGIFGAEEQEVKLLKKHLVGEIRKIAGLSFFTGTIMGKDVVLVCSGIG
KVNAALCCQILISEFKVDAVINTGAAGGLLEGINVFDMVVSTDAVQHDVD
ATAFGHPIGQVPMTKSPFWPADKKLKTLALKAFKAMQKESDDEHIKNLKL
IEGRIASGDTFVSDKKLRERIIKEFNPACVEMEGAAAAQVCCINKIHFLI
LRSISDTAGKDKAAKISYEVFSAQAAKDSSLLVLQMLKML
>TDE0870 phosphatase/nucleotidase
MKKRLTFILISVFVIFSFTSCLETRVKESGVRSKREMLATGKQSDEVKLT
HAVIRKGEAGKDNVTLTFGVTGDVHGRLYPFEYAVCEEVPGAGFSKTFTL
AQELRKENPNTVLIDVGDTVQDNNAELFNDLETHPMIQALNYMNYDIWVL
GNHEFNFEKEFLARNIRNFNGAVLSANIRNEKDKSFFVLPYQLLEVEGVR
IAVVGLIPPHIPMWESSSPSHFKGLTFEEPLDAARRTVDSLKGQYDVLVG
AFHLGRNAEYGSTGGVIEIAKQIPEFDIIFGGHEHARYASIVDGADGDKT
WIIEPGAYGWALAVGEIKVKKEKDKWKVVSVKAENRETKNVLPNKPMEEE
FKFVHQTSLSDANTVIGNITEDFIKRVDYITGEDKVTTMPTIQLEDTALI
DLINNVQLYYTKADVSSAAAFRSDMNLKAGLFKKKDVAFIYKYANTLMGV
NITGENLLKYMEWSASYYNTTKKGDVTISFDPKIRSYNYDMFEGLTYDID
ISQAPENRIKNARIKGKPIDPKKNYKLAVNNYRFGTLTKLGLISEKDVYY
DSYMKMQDAGRIRDLIVKYVKEVSKGVIKPVTNNNWKIIGFDPDVKGKEE
ILNKIRSGEIKIPKSEDGRTPNVKSINIYELK
>TDE2193 deoxycytidylate deaminase, putative
MVDTKEKYKRPSWDEYFMDVCRAIAKRATCDRGRSGCVIARDHQILVTGY
VGAPTGLPHCDDVGHQFKKLQHEDGSVTQHCVRTVHAEQNAICQAAKRGI
SIDGATLYCKMTPCRTCAMLIINCGIVRVVAEKRYHDSADTIEMFKKAGI
ILEHISDSLEEYKGQ
>TDE2242 antigen, putative
MKKTLIFILMILVLIVSSCNLFLKEEYGELIVSFDGTLPDGARALDSNGL
PVLSSSPMKINIIREDGYTITRELSAEEPKSLVELVPVGEKIEIIVTAIN
PSGQWSGRAFHTVVSGQNHVKVLLNKNISGLNNLLFTQTKDLFSTPPYNL
TLYMNGKEINAHPSQSEYSFGRDSLGRLYISVNEGNSHVSRYTSEGELLN
HVMESIVYFACDYTTRKMYGINGSGGVYEIDENFSISSLTPPLNLSHYDG
AAAIDNNLFVWICDDGSNPLKIQAKNLDGSHPSETEIKDHIKITDCKESE
VKDMFIRGKYVYVLFNTMNDELTGNSRNLYSLGGVVRYNINNLTAPPVKI
GFSNSVSFENSLLKNYDYSANFYGAVKVIGFDEENIYIADDGFDAADTPA
GARIVKNRNRIAALNIATNALSFSDAGPAKWYNEWKEWRTPNTKMIVWES
LYDGSSRSGMSYYQVEKGDENLLGANSFITSDVSNPTGVLYSDVFCYDSA
GNFYVSGKDNSDEKLYRYVLKDDGNYETDGEKDISEKPTTIAVSVSSVPD
DAGKTILFYYFESGNGHNIGRLAWYTDDFANAVQRRNITLNDLDQNDTVT
AMTANKDGIFVAVKTVTGKDSPNEKYKITVKKYAHQPLGSPAIISAVETV
TVVDETSTNYPNVVVPPSHWTAEQANAYINEDLNALYISDGVLYGLTTNQ
KGYIKDIFSKATEVFIGGKLLKIGNTKSLGSYVVVLYKNDGLRPATSGEF
APYRFIAVKPKKLVIASDGYYGKGTAPRNKNKVFVFDIGNWAHPDETVTQ
TRINLSKQLGYSGNSFIWTIE
>TDE2613 conserved hypothetical protein
MIKIALGISIILIFFLLGLVIGKYKERSLNLKRVNEARKDAVKRSRAVLN
GQLSEQLAPFFPDFPANPTEIRFIGQPVDYIAFNGASQGTITDISFIEIK
TGSAALSPVERALKDAIEKKKIKYIEYRADLNKK
>TDE1112 adk, adenylate kinase
MNCIFLGPPGAGKGTLAFEVSKSYKIPHISTGDLFRAAIKEQTDLGKKVK
AVIDSGALVSDDLTIALVKERLERDDTKKGFILDGFPRTIAQADALEDIV
KIDSVINFDISDDEVIKRLSGRRVCSSCGQSFHIEFVKPKKEGICDSCSG
DLMIRPDDKIEAIQKRLETYRNQTAPLIDYYTKKDLIVNIDARPASEKVL
ASFKVKFPH
>TDE1684 apt, adenine phosphoribosyltransferase
MTIAKIRCRLFIMKDKIIDAAIRRVPDFPKKGILFYDITGILVNPEVFSY
CLDKMTEMYKDKKVDAVAAIEARGFIFAAPFAYKMGIPLILIRKKGKLPG
ETYSASYDLEYGQASVEVHKTDVVKGQKVLLLDDLIATGGTLNAARSILE
EGGAKVVGFCGVVGLPFLNYSKVLGDLPVKTLIEYDSEKI
>TDE1931 cdd, cytidine deaminase
MEISSQLENLFKTALEAAKKAYAPYSNFHVGAAILLEDGSIVTGVNIENR
SYGLTNCAERTAIFKAVSEGKTDFKAIAIATPDADYPVSPCGACRQVISE
FMGGDTPVIFGSSLDNVVLTDVKGIYPFDALHELKK
>TDE1087 cmk, cytidylate kinase
MKKTAFKIPEGKELRIAISGPSGCGNTTVSTLTAKTLNLPCINYTFKNIA
KELNISFEEVLRRAQEDFSFDKTVDKKQIELAEASSCVLGSRLAIWLLNQ
ADLRVYLRASIEVRAKRIQKREGGDIEKIKADTDLRDMEDTRRYKELYGI
DNTKYEKADLIIDTDNLTPEKIVKKILSELYSRGLLI
>TDE0448 deoC, deoxyribose-phosphate aldolase
MELNKYIDHTLLKPTASEKDIIKICNEAKEYHFASVCVNPCNVSLVRKEL
KGSDVKVCSVISFPFGASSTEVKVEEAKKAIEAGAEEIDMVINVGKLLEG
DLEYTQNEVSAITKACHEKNVLLKVIVETCYLEEKNIADICAIIEKAGAD
FIKTSTGYGSRGASVEDIKLFKKYLKKDTKIKASGGVRTREDAETYIGLG
CSRIGASSGIAIVTGK
>TDE0463 deoD, purine nucleoside phosphorylase
MSVHIAAKQGEIADKILLPGDPLRAEFVANNFLENPQCYNKVRGMLGFTG
TYKGVRVSVQGTGMGQPSFSIYANELFNEYGVQRAIRIGTAGALQKDMGL
RDVVLAMAASTDSGINTHRFRGCHYAPTADWSLLKNAYDHAQKMGIKPLV
GSIASSDVFYDDLETWKMWAAYGVLAVEMEAAELYTLAAKYKRQALAVLT
ISDNIVTQEQTSAEERQTTFKTMMEIALEAIIA
>TDE1042 dut, deoxyuridine 5'triphosphate nucleotidohydrolase
MEVFTKLKEGALLPEYKTSGSAGADLRALIEEPIILKPMQRCLIPTGLSV
ELPKGIELQVRPRSGLALKHGITVLNTPGTVDSDYRGELAVLLINLGNED
FKIENGDRIAQAVIAQAIQADFLQKDELSNTERGAGGYGSTGIA
>TDE0019 fhs, formate--tetrahydrofolate ligase
MKTDIEIAREAKLKKIAEIADGLGIHDDNVIPYGKYIAKVPYSVIDDAKV
KKNNLILVTAITPTKAGIGKTTVSIGLALGLNKIGKKAVAALREPSLGPC
FGMKGGAAGGGYAQVLPMEDINLHFTGDFHAITSAHNMISALFDNYIFRA
QGTPKAIKTVLWKRVLDVNDRNLRQVVTGLGEGNGVVMESGFDITPASEI
MAIFCLAKDIEDLRRRIENIILGYDTENNAVKVKDLGIAGSIVVLLKNAI
NPNLVQTTENTPAFIHGGPFANIAHGCNSVIATKTALTYGEYVITEAGFA
ADLGAEKFFDIKCRKAGLNPKLTIIAATTGGLKMHGDVPEKEISKPNAEA
LKKGLANLDKHIENMKKFGQTVVVALNRYGYDIDSELELVRKHCEAQGVG
FAVNNAFVEGGKGAVELAELVVKTIETNPSKPLKFVYEDKDSIKTKIGKI
CKEIYGAADVTYSGAADKMIKKIEEAGMADFPVCVAKTQYSFSSDPKLYG
VPTGFEMNVRDIVLNSGSEMIVAIMGDMMRMPGLPKDPQAVRIDLVNGNV
EGLS
>TDE1718 guaA, GMP synthase
MKKKPLSAKIVFMKITEKILIVDFGGQYNQLIARRVRDLNVYSDIVPASK
ALDYIRENKPIGIIFTGGPNSVYEEKAPLPPKEIFNLNIPILGICYGMQA
MAHCLGGKVEKSLKREFGKTLTKFDTGIPLFKNIKDKSSVWMSHVDCVSR
LPEGFVSAAQTANTKNAAMANKEKKLYGIQFHAEVEHSEEGQNIIKNFLY
NVCGAKGDWNMKSFLAEAIKDVQNTVKDGKVLLALSGGVDSSVLAALLNR
AVGKNLTCIFVDHGLMRKNEGDEVEAAFRDTPMNFIRVNAESRFLGKLKG
VSDPEKKRKIIGEEFIRVFEEEAEKIGTVDFLAQGTIYADVVESGTKGSA
VIKSHHNVGGLPDHISFKSLIEPLKTLFKDEIRNLGTELGLPDYLVHRQP
FPGPGLAIRIMGEITEEKLDILREADAIWRSELEHADIKKDLSQYFAVLT
STKTVGVMGDFRTYDYTLALRAVKTSDFMSADWVRIPYEVLDKVSSRIIN
EVKGINRIVYDITSKPPATIEWE
>TDE0341 nrdA, ribonucleoside-diphosphate reductase, alpha subunit
MQIIKRNGETKNYEPEKIEGAIRSAFKSVENSPHTDLDTIIPPLVKEIEE
DILELTKNGSLVQVETIQDLVEKTLIEHNYYAEVKNFILYRVGRTKRRDS
RQMISRFFDTIEIQSVLTEIQNDFTSDEYSLNLLAHKFLSFRKENMSETE
SLAMLIKASVELTAQDAPDWEFIAARLLMLQFKLKLKTELEKRQIHSFYE
KIKYLENEGLYGTYICEAYSRDELEEAASFINEERNKLFTYSALDLLLRR
YVIHTHSNIVLESPQEMFLGIALHLAMKEKLKRLEWVRRFYDMTSTLKVT
MATPTLSNARKPYHQLSSCFIDTVPDSLDGIYRSIDNFAKVSKFGGGMGL
YFGKVRAVGSPIRGFMGAAGGIIRWIKLANDTAVAVDQLGVRQGSVAVYL
DVWHKDIPEFLQLRTNNGDDRMKAHDVFPAVCYPDLFWKTVRDDINSSWH
LMCPHEILKTKGYALEDFYGEEWEKRYKDCVADSRINKREIPIKELVRLI
LKSAVETGTPFAFNRDHANKTNTNPHKGMIYCSNLCTEISQNMSGIKHKN
IEIKTEDGDTVVATTTIPGDFVVCNLASLVLGNIDVNDEQEIDTIVSSAV
RALDNVIDLNFYPIPYAQITNSRYRSIGLGASGYHHALAKNGIAWESEEH
LNFADKVFERINYAAIKASSQIAKEKGSYSYFEGSDWQTGEYFKKRNYVD
ENWKALTEEVKSNGMRNAYLLAVAPTSSTSIIAGTTAGVDPIMNKYFLEE
KKGSLMPRVAPSLSPETYWLYKNAHHIEQGWSIRAAGLRQRHIDQAQSVN
LYITNEFTFSKVLSLYVKAWEEGLKSIYYVRSRSLEVEECESCSS
>TDE0335 nrdB, ribonucleoside-diphosphate reductase, beta subunit
MITEKTILPHKALFNENGDIETHKRKMIGGNTTNLNDFNNMKYSWASDWY
RQAMNNFWIPEEINMTTDVQDYRKLSIPEKTAYDKILSFLIFLDSIQTAN
LPNVGQYVTANEVNLCLTIQAFQEAVHSQSYSYMLDTICSPEERTEILYQ
WKDDEHLLRRNKFIGDLYNEFQSDKSALAFLKVCVANYILEGIYFYSGFM
FFYNLGRNNKMPGSVQEIRYINRDENTHLWLFRSMIQELQKEEPQLFTPQ
NVELFRAMIKEGCEQEIAWGDYVIGNDIPGLNSQMITDYIQYLGNLRCEN
LGFAPIYDGHREEPQSMSWASQYSNANLIKTDFFEAKSTAYAKSSAMVDD
L
>TDE1331 nrdD, anaerobic ribonucleoside-triphosphate reductase
MEEKTTNQTVFPEWKSFLGTMEKAKPEILRSVVKRSGEIEAYNRKKIEQA
INKAITAVEGSPNDEKAVFLTDKVEEKLKNIMASRYAHSIPAIEEIQDVV
ELVLIEQQEARLAKAYILYRAKREAVRDAESLMLNINSTMDGYLSQSDWR
VKENANVNFSLGGLILHNSGTITANYWLKNIYTPAIAEAHITAAFHIHDL
SMFSGYCAGWSLRQLIHEGLGGVPDKITSKPPKHLSTLIQQIVNFLGIMQ
NEWAGAQAFSSFDTYLAPFVKKDKMSEANVKQCLQSFVYGVNTPSRWGSQ
APFTNITLDWVCPPDLANQKAVVGGETQDFTYGDCQKEMDMINKLFIELM
LEGDAAGRGFQYPIPTYNITSDFDWSSPNAKLLFEMTARYGTPYFQNFIN
SDLNPGDVRSMCCRLQLDKRELRKRGGGLFGSDEFTGSIGVVTINMPQIG
YLSKTEKDYFDRLDYLMDIAKQSLEIKRKVIEKLLEGGLFPYTKRYLHHL
NNHFSTIGICGMNESCLNFLGEDIVSPRGKAFAEKVLTYMRNRLADFQEE
TGSLFNLEATPAESTSYRLARHDKNQFPDIISSGDAEPYYTNSSQLPVAY
TTDVFEALDHQESLQRKYTGGTVFHIFLGESIKDWESCRDLVKAVANNYR
IPYFSISPTFSICPVHGYLEGEHFECPYCKREKQAKLELKLAELEKEKAE
VLSVSSKI
>TDE2191 pdp, pyrimidine-nucleoside phosphorylase
MRATDIIMKKRGIKGQAIEPLNRKEIEFIVNSYVRGEIPEYQISAWLMAV
YFNGMTFEETAILTDVMLHSGKVMDLSSLEGPFVDKHSTGGVGDKLSLPL
APIVAANGVKVPMMSGRALGHTGGTLDKLEAVTGYRTNLTEAEFRNFIEK
TGFAMTGQTKEIVPADRLLYAMRDVTATVESVPLITSSILSKKVAEGSEA
LVFDVKCGKGAFMKTLSDAKALAVSLVGTAKAMGKKARALITNMNEPLGT
MAGNFLEIEETIDILKGQGPADSTELTLQLAAHMLVLGGKAKTEEEGLSL
AKEAVSSGKALDLFIKNIELQGGNPKTLMAEYKTRRSKFFEELKAERDGF
IESINAFEVGMAGVNLGVGRNKTTDPVCPDAGVEILKHKGDSVKKGDLIM
RVYGKDSASVSASMPLLKNAIEYSDKAPQKNKLIFKIIKQEEL
>TDE2723 prs, phosphoribosyl pyrophosphate synthetase
MNYLESNNLAIIACPGGEEFANLTIKNLKHIYARKLYQQSEKLAKRYNTS
SEDMIQKFNFYSDLFAGRMSVNKDTNKIHVPKFKVDARFTYFMNGEFKTE
LLETVRGKDVYIFQDVENKQEITINEGKNKEVFSVNDHLMSLIVTIDAVR
HAGAGRISLVLPVYPYSRQHKKKGREGLTASLLGHIYEDLDVEQIITLDI
HSREIENSFHSARLQNLHASYQIIRELTRILDLSADSEEQFVVVSPDSGA
VDRNKFYSSGLQKPLAMIYKERDYSVVTQNAKQSNIISIKLLGDVEGKNA
FIADDMLGTGGTLLKAMEFLKSKGAKKVIAAVSLPFFTGDAIQQFDEAYS
KGLFYRVIGTNAVYHTELKQKEWYIETDVSGLFAQVITRLHENLSLSSLL
DNRDIIEKLLKNAAIPKK
>TDE0686 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MISRNAAFRESNLPLPSKQTGKVRDWYSPEEGKRLIVTTDRISAFDRVLT
ALPYKGQVLNQLSLWWFENTKDIIKNHIISCPDPNCIIVTEVKPLPIEVI
VRGYITGVTSTALWYRYSLGERNIYGYDFPEGLKKNQALPKPIITPTTKG
GPTGHDERLTCDEVVSQGYLSKEQWDFVQKAALALFERGQKSAKEAGLIL
VDTKYEFGVDKNNNILLIDEVHTPDSSRYWKLDTYEQRLKEGKEPENFDK
EFVRMAYAAKGYRGDGEIPELDENVWNEAIQLYITAYEKLTKSKFVPGEY
PAEERIVKNLKKAGLM
>TDE1267 purD, phosphoribosylamine--glycine ligase
MNILLVGSGGREHAIALKLKESPSLGKLFIAPGNGGTALLGENVPIKADN
IEGLADFALSASIDLVIAGPEVPLCLGFEDLIKEKAKAQNKKIAFFGPSK
ACARLEASKDFSKEMMSLLSIPTARYSSFTDFQKAKKYIEGLDYPFVIKA
DGLAAGKGVILPDSKEEGIAELKNIMIEKQFGTSGDKVVIEERLEGEEVS
ILAFSDGEKIAVMPPSQDHKRLKDNDEGPNTGGMGAYAPTPICSYEEAEK
YAALTILPIVKEMKKRGTPYIGVLYAGIMLTKDGKGFTPKVLEYNCRFGD
PETQVLMQLFDGDLALTMSYCAEGRLGEAMPKWKKGYAATVVLASEGYPL
SSSKPVELSASELEGSAEVSVIHAGTALKDSKIFASGGRVLCISSNDKSL
QKAMDNIYEKIKTIHFPGVQYRKDIAKRGLEHLNQLK
>TDE2407 purF, amidophosphoribosyltransferase
MSKDDIFKSSLGEECGIAAVWDSNSYKTENPERLPFRPDDAARSVFYALF
SLQHRGQEAAGMAVSNGKHIRVFKKPGLVSNIFTEHDISNLQGYAAIGHT
RYSTTGSSSFGNIQPFYIETMYGPIALAHNGNLVNAPHLRQKLLERGVGL
SSTSDTEVMIMMLAAAKGDSWAERIASCMREWEGAFSIAVLTVEGIYIAR
DPWGFRPLCVGSFQEGVSVAASESCALLTLGCRDVTEVKAGEILKLVDNG
AELCMRIPPKEPLSPCIFEYVYFARPDSVWNNASVHVSRVNFGKELAKSS
PVEADIVIAIPDSSRSAAIGYSQESGIPYDEGFSKNRYIGRTFIQPTQKL
RDQGVAMKFNVLSEAVEGKRIVVVDDSIVRGSTMGPLIKMLRGAGAKEVH
IRISSPPVRYSCFMGVDMGDPENLIAHKKSVEEIREHIGADSLVYLSQES
MLKAMKDAGANTHFCCACFDGKYPVDVSGAADKNSFE
>TDE1896 purH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MGLVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSE
YTSSPEILGGRVKTLHPMIHGGILARDTKEDRAELKALGFSGIDIVIANL
YPFEKTISSPDSTESDCIENIDIGGVALLRAAAKNYSRVTVICDPADYDE
VSSEIEKTGEISLSLRKRLAIKAFDLCTRYDAAITSWLSGLSRLSGGIEE
KTSLTLCAYPGQDLRYGENPHQKAWLYTNEPKAGPLGGKVLQGKALSYNN
ILDADAAWRAVSMFTKPAAVVVKHLTPCGLAEINEEPAKSSSSSLPNSEV
SLALRAAIDCDPVSAFGSIIALNRPFDKASVEALGALFVECIIAPLFTEE
AKELLSGKKNLRLIEAPILQEKEPYEYKSVLGGFLKQEKDLGDPEGTEYK
DAAERKAEPFERALLQFAMKACTMVKSNAILLAAPIDLSNPQKGFCSVGI
GCGQPNRVDAARQAIERAGERVKNSVLASDAFFPFPDTIEEAAKAGIKAV
IQPGGSIRDYLSIEECNKHGMAMLITGVRHFKH
>TDE1279 purL, phosphoribosylformylglycinamidine synthase II
MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSE
HCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPW
VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDV
MGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK
MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSAGDHIISLGG
KTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQ
GLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSE
AQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII
NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHA
VNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA
ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP
NRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPP
SLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIP
SGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL
SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGA
SIYEIGKTCGKAGLKL
>TDE1266 purM, phosphoribosylformylglycinamidine cyclo-ligase
MNEMKNKNQEQPKGKSEDLSKDKSSVYSASGVNIDAGNEAVRLMSAAVRS
TFNKSVLSDVGTFGGLFGTEELFKMKKPVLVGSTDGVGTKVKIAAEAGRY
TTIGQDIVNHCIDDILVQGAKPLFFLDYVASSKLDPQMIADIVGGMAKAC
KESGCALIGGETAEMPGVYMEGEFDIAGTIVGAVDEEKILPKKNIKEGDL
LIGLASDSPHTNGYSLIRTAFKGVDLNTVYPELKAPLHEVLLKPHRSYLN
AIYPTLQEHPEIVKALAHITGGGFIENIPRVIPAGLVIKVKKGSWPVPPL
YPLIQKLTGASGDEMYRVFNMGIGMIAVVSPDMAEKYRELVGEESWIIGK
LEKAGNQTQKAVTILE
>TDE1897 purN, phosphoribosylglycinamide formyltransferase
MKKKLAVLVSGNGSNLQAVIDGIKNGSIDYKIEAVVSNKKEAFALSRAER
EGIKTIYLPFKKGSSRNEYDALLAEKVKEFKPDYVLLLGWMRILTDSFIA
TFKDRLINLHPALPGTFPGTEAIERQYEAFMKGEISRCGIMTHFVPDEGV
DSGPVIFTEEVPVFQGDRLEDFEKRVHEAEHRLVIKTLKFLSKV
>TDE1405 purQ, phosphoribosylformylglycinamidine synthetase I
MKPRALVLHATGTNRDGDAARALELAGAEPEIVHINKLKAKEKNWKDYEI
LVIPGGFSYADALGAGKLFALDLSNYFFDEVSEFVAAGKPVIGICNGFQV
LVKSGILPGKEKDGKVILDKDGYKNRQATLTYNKQGRFECRFTTMIPQKS
NCIWTKDLKGNIHCPIAHGEGRFLTDSQKTLDDLFEKGQIALVYGGKDAE
KSIPANGEYPFNPNGSLADIAGICNTKGNVLGLMPHPENNVVIRERDSEE
EKERTKLCLDMWKAGVNYVL
>TDE0129 pyrBI, PyrBI protein
MENKFMGRSLTVIDDLSIDERKYLFDKTKRLKKAIQEDDQKVMDEFRIND
KDFGIYEVFLEPSTRTKESFRNAAKFHQVKLSDLAAESSSFNKGESYADT
FNTLAGYQNSIFIVRSKVEGVCRWLEDEAQAFYQRNNLKRKPAFINAGDG
KHEHPTQELLDEFTFIEDNNWSFDKIHIALVGDLYHGRTVHSKADGLKIF
KSVKVDLIAPAELAMPEYYKVRMQENGFTVREFSSIEEYLRQADVALIWY
FTRPQLERMGEQVLKKQDELRRSITFRKEFIEKLPENTRFYHPLPRHRVH
PTIPTFLDATPLNGWERQSINGMYVRMVLLSMIAGKIGDDYKGPEPKSCE
RVEDEDYIVEVPINNSKESKVETFSEGVRPIQNGIVIDHICRGDKPSVIR
HHMSKIINVMGLEEGKGGEWVSTSTKDKGTFKGIIFRPGEYKFSRADLKR
LSAVASSCTLNLIKDGKIQSKYRTHLPPRIYNFEDLICKNEACISHPAQS
EGVPAIFYRTIDNRYACQYCGTIHTFKEIWGEKKN
>TDE1001 pyrE, orotate phosphoribosyltransferase
MHKDEKKIAEVQKKYGALLAKTAFELGALKLSPNEPFTWASGYRMPIYND
NRRFLALPEMRRTIAEAFAELLKAVDFDPEWLAGTATAGIPHSVSLGDLL
QKSVSYVRSGGKDHGLKNQIEGLGANADYKGADVLVVEDLISTGGSSIKA
VEAVRNANGKVPFCFAIFSYGFAEAEKAFAELKPSCIPVTILNYDIMLDE
AVKQNYISEENKKSLGEWRLDPFGWGEKHGFPKV
>TDE2110 pyrF, orotidine 5'-phosphate decarboxylase
MNYIDLLKTSAKKTNNCACMGLDPIFEAVPNKTGMVKDNLVSFFKELFNK
MQEKNLIPAAFKPNIGYYSALDKPREKDFSGSESLAEILSLIEKHFPGIP
VILDSKRGDIARSSLNYAIEAFDGWKADAVTVSPYMGSDSILPFISEKYL
DKGAYILNRTSNPGAKDFQNLKTDSEGKNNSELYIEVAKKIAFYAKEFPG
TGAVVGATGMEELKIISGIYAQAGEVPMLIPGVGSQGGDAKTVMEVLKNS
GCNLALIRINSSSALTHPWKKAPVPENYLELCINNIEKLLNETAINNISF
>TDE2692 pyrG, CTP synthase
MKSKFIFITGGVVSSLGKGLTAASIGMLLKSRGYSVVNQKFDPYLNVDPG
TMNPYQHGEVFVTEDGGETDLDLGHYERFTDVPLHKFNSTSAGKVYLAIL
DRERAGGYNGGTVQVVPHVTDEIQSRILGTAEQTGADFVISEIGGTVGDI
EALPFIEAIRQIRYTVGKENCMFVHLGLLPYLKECGEIKTKPMQHSVKEL
LSFGIQPDILICRSEKRLSKSTREKLSLFSNIPQDAIIENLTAKSIYEVP
LMLEEAGLGKVLCKLFNIENKEPNLEEWKKMVQTYYNPEKEITIALVGKY
VELPDAYLSVAEALTAAGIYHKTSIKLLWIDSKKIETKEDAAAFLKDADG
IIVPGGFGDRGINGMLLTAQFARENKIPYFGICLGMQISAIEYALNALHI
EEANSSEFDKNAKNPVIDLMPDQKDVKIGGTLRLGLYRCMIAEGSLAEKA
YKSHEIQERHRHRYEFNNLYREKFDNSDMIFSGLNPERNLVEIVELKSHP
WFVAVQFHPEFASRPNKPHPLFRDFIKAAVDNKINR
>TDE2599 tmk, thymidylate kinase
MILPNFVVFEGIDGSGTTSQIRLLKERFESEDKSSLVSFTQEPTSGPIGT
LIRSALQGSFKLAPETMTRLFAADRCEHIYGLQGILKQVNDGRAVFSDRY
VFSSLAYQTAAGAADLAKLQNDGFPLPEFLFFFDLPVDISMNRVMGRSNV
LEIYEEKTFQYKVQDEYKKIIDEYRLKEPNMNIVIINAVEQIEEIHEKLW
SILKDLPKI
>TDE2251 uraA, uracil permease
MSHKRIYQVDEKVPAGLFLPLSIQHTFAMFGASVLVPIIFGIDAGIVLFM
NGVGTLLFIAITKGKAPAYLGSSFAFLGPAGLIISSMGFQYAQGAFIVTG
LLGCLIAFIIYKFGTSWINVILPPAAMGAVVSLIGFELTGLTVRGGTIGA
NIMTESASRGDIIVFFITIGAAVLGSVLFKGFLSTISILIASIAGYIAAI
FFGMVDFSIIREAGLFTLPHFQLPKFDLMAVITMLPVLLVITSEHISHQV
VTSNIIGKDLLKNPGLHRSIFADNFSTALSGLVGGVPTTTYGENIGVMAV
TGIYSVYVIAGAAIISICMAFISPLAALIRTVPGNVIGGITFLLYGMIGA
SGIRLLVDSKVDYSKSKNLILTSIVFTTGLSGLSIKFGEIEFKGMVLASL
VAVALSLIFFIFEKLGVLEE


# Treponema pallidum

>gid:49  TP0045  adenosine deaminase, putative
MKSLEYYRSQPKADVHTHLNLSMKYERYKQWSGVVIPNFPRKMRGLDEMH
EIIGEYTRPQCKTAQDVLNLFTMSIEDAIADNVVVMETSVDIGFITHYEE
NLDHFLCDLSDLHRRYKRNVTLHFELGISKIRERSFVEQWAEPMMRSGIF
ENIDLYGPEISEGIEDFIYIFKLAEKYHLKKKAHVGEFSDAQSVRHFVEI
FNLDEVQHGIGAATDENVLRFLAERKVRCNVCPTSNVMLNAVECLEKHPI
KKMMDAGVRVGLGTDDLLFFGKTNSEQLFDMVSCGLITELHAEALLAVR
>gid:57  TP0053  ribonucleoside-diphosphate reductase, subunit beta (nrdB)
MMESSTILQRRALFNEAGDIELHKRRMVGGNTTNLNDFNNMKYPWVSKWY
RQAMNNFWIPEEINMSSDVQDYRNLSAIEKTAYDKILSFLIFLDSIQTAN
LPNIGQYITANEINLCLTIQAFQEAVHSQSYSYMLDTICSPEERNDILYQ
WKDDEHLLARNKFIGNLYNEFQDDKSVLALLKVAIANYVLEGIYFYSGFM
FFYNLGRNNKMPGSVQEIRYINRDENTHLWLFRSIIQELQKEEPQVFTAR
NVRLFRDMIREGCEQEIKWGDYVIGDQIPGLNRHMVADYIRYLGNLRCEN
LGFEPLYEGHRVEPESMSWVSQYSNANLIKTDFFEAKSTAYAKSSAMVDD
L
>gid:103  TP0099  uridylate kinase (smbA)
MVTVLSLGGSIVAPETPDIELLGRFVRSVQRYLYEDASRKLIVVSGGGAP
ARTYQNAYRALRRSLSSPACAKPAHEGDNQEDRELYATAEHVELDWIGIM
ATRLNAQLLKSLFGILCPNPVVYDPTAANVFSGQVLVAAGWKPGFSTDTD
AVLLAERYSAKTVINLSDVAHVYTGDPRSDKDAKALTSLSWDDFLLLVDK
EWVPGSHVPFDPVASVRAKKSGIQVICATGRDLPNLERILNRQEFVGTTI
G
>gid:108  TP0104  5'-nucleotidase (ushA)
MKRFIPHRVIHAVCIGLALVGCRKLDSRAGDFELTIIHINDHHSHLEPEP
LELAVAGERLRAAVGGYAALVHEIQRLRAESKNALVLHAGDALIGTLYST
LFRGRADAVLMNHAGFDFFTLGNHEFDNGNEGLKEFLHYLEVPVLSANVV
PNAASTLHGLWKPSAIVERAGERIGVIGLDTVKKTVESSSPGKDINFIDE
IEAVRRATVEMQQQGVNKIILLSHAGFEKNCEIAQNISGIDVIVSGDTHY
LLGDESLGRLGLPVVGEYPRKIMSPAGEPVYVVEAWEYGKCLGELNVVFD
RTGVITSAVGMPRFLLHTNTLQKKGADRKNYPLEEAEREALLVALRMTPE
IIFAQENDQIISVLEEFKKEKEALGAQAIGVITGASMRGGSVHRVPDAQN
PQGSVATRFVAETMLSDIQSFGAGKVDCVIQNAGGARSNIQPGEITYNDA
YTLLPFSNTLVLVDVSGAELKQIIEDALQFALGDGSTGAFPYGAGVRYEA
RQEPDEHGKRVIKLEVQKKDGAWVPVDERAPYRLGVNSYIARGKDGYKTL
GEIVSTRGAEDTYLRDAESLIKFLRAHKNFRAYTDSNVIFRLK
>gid:179  TP0170  pfs protein (pfs)
MTVGVFAALGEEVARVRECLGGVGTERAGLTFYVVSVGALQVVYVCGGVG
KVNAALCTQLLISEFGARVLINTGIAGALDERLCVFDVLVSVDAVQHDVD
VTAFGYQKGRIPRMDSVEWTANTALRYLVREAFDLCTRDPEWTEGACALS
GSGDPPSRVSRLVEGRVASGDLFVSDAQTRARIIREFGAHGVEMEGAAFA
HVASVNGVPFVIIRCISDGAGAEQDVSMSYKEFSTRAARRSALLTLRVLE
RLSALRTSVVASLFPMVVV
>gid:185  TP0176  T. pallidum predicted coding region TP0176
MTNVFKKNIRALRMRYQDIALTLERTHSNGIYAGTLTAHTGENIPFFRNN
RTLHSRYNPWIEAERTLPAQHASFFFVASGQVSTSVFS
>gid:278  TP0264  deoxyribose-phosphate aldolase (deoC)
MELNAYIDHTLLRPSASEAEVLRLCQEAQHYRFASVCVNPCHVALAAGAV
RGTAVRVCSVIGFPFGTHVTEVKCAEAQRALDDGAQELDMVVRIDKVCAG
EREVVEREIAQVAARCHARGAIVKVIVETALLDEMHIAFACSCVEAGHAD
FIKTSTGYASRGGTEGDIQCFKKYLKGETKIKASGGIRTRAQAQRFIELG
CARIGTSNGVAIMEERAS
>gid:292  TP0274  deoxycytidylate deaminase, putative
MGQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGY
AGAPRGLLHCDEHGHQLRTVQHEDGTCTQHCVRTVHAEQNALCQAARLGI
GLEGATLYCTMTPCRTCAMLIINCGIVRVVAEKRYQTATESIMLFAQAQI
ALEHIYQNPAEYGTPS
>gid:312  TP0294  phosphoribosyl pyrophosphate synthetase (prs)
MRCSGFTDLAIVACPGGEHFADETIKHLTRVCERKFHQRMDRLTDRYGLD
SGSVIRDANFYRDLFSTELCAHDDVRRFNPPHFKVDAQFICFLNGELKTQ
INECIRGKDVFIFQDVENHQPVLVNNGKSKKIFSVNDHVMMLIVTIDAVR
HAGAGRVTLVLPTYPYSRQHKKCGREGLTAGLLGSVYEYLGVSHIVTLDL
HSREIENAFHRTRLENLHASYQIIRELAKIENLSDPDIPFVVVAPDSGAV
ERNKFYSSGLKKPLAMIYKVRDYSVVAQNAKQSNIVEINLLGDVEGKTAF
IADDMLGSGGTMLKAMEFLKSRGAKQVIAAVSLPFFTGNALELFDEAYEK
RYFSRIIGTNAVFHTQLSHKQWYTETDVSGLFARVIARIHHNQSLSSLLD
DRSIIERLLHARLSVAGTPRA
>gid:323  TP0305  CTP synthase (pyrG)
MDPAFIFITGGVVSSLGKGIAAGAIGLLLKSRGISVVNQKFDPYLNGDPG
TMNPYQHGEVFVTQDGGETDLDLGHYERFTDVPSSRFNSTTAGSVYRAIL
DRERAGGYGGATVQVIPHVTDEIQARIRAAAATTGARVVITEIGGTVGDI
ESLPFIEAIRQIRRVLGKERCLFIHLGLVPYLPSCGEMKTKPLQHSVKEL
LGLGVQPDVILCRSERHITDAVREKLSLFCNVERRAIVENVTARSIYEVP
LLLEAEGLGALLCERLRLFDTCCGGQVARNLGAGGAQSAVLGAGGTVRTD
GGLHPAAGQGAEPDLTAWRAMVRALYYPRRELTVALVGKYVSLADAYLSV
SEALTAAGICHRARVDMRWIDAEEICSVQDAGHALADADALVIPGGFGVR
GIEGMICAVSHARVQNLPYLGICLGMQIAVIEFARNVLLLASAHSREFAV
DTPHPVVDLLPGCVDTPTGGSLRLGQYRCLLAEGSRARALYGRGEVWERH
RHRYGLNAAYRARFEASALRPVGVDSDCGAVEVVEHGEHPWFFGVQFHPE
FCSRPNRAHPLFRALVAAGLERKDSRS
>gid:361  TP0342  cytidylate kinase (cmk)
MSNRCDVSGNKAVRIAVSGASGCGNTTVSALLAERLGLPLVNYTFRNIAR
ELGISLSEVLERARTDNHFDKAVDARQLCLAMRSSCVVGSRLAIWLVKDA
ALKVYLLASLKERVKRVLQREGGDVQDVERFTSMRDAEDMSRYKKLYRID
NTNYSFADLVLNTEGCDQETVVSIIIEMLRARGIAW
>gid:373  TP0354  thymidylate kinase (tmk)
MNILHNFVVFEGIDGTGTSTQLRALERHFQARKDMVFTQEPTGGEIGTLI
RDVLQKRVIMSSKALGLLFAADRHEHLEGAGGINDCLAEGKIVLCDRYVF
SSLVYQGMAVSGSFAYELNKEFPLPEVVFYFDAPIEVCVERITARGLQTE
LYEYTSFQEKARKGYETIFRKCRHLYPAMKVIEIDAREEIEVVHERILHH
LREYRRLK
>gid:458  TP0438  conserved hypothetical protein
MRAVDFLRRATVCWYMRIYLASNNAHKHAEFSSLFPMHTILLPKDEGIDF
FSPEDGSTFFANARQKADALYDVVHAPVLADDSGLCVDALDGDPGVHSAR
FGAQHGVHTDTARMQLLLERMHGRQDRACSFVCVAVLKLGSVPLCVGRGV
CRGVLTTEMSGVEGFGYDPIFLLPHLGRTFAQLSIEEKNRVSHRALAALR
LAQVLAMMQLPRALRYELKLLRGARRMTRGGVLRPGAPCAQRKGQTAQTA
RRHKFYARARRCARRIHRA
>gid:468  TP0448  uracil phosphoribosyltransferase, putative
MEGQTARRVITEAKFLDDCLTERDSYYLSKLDELYSSAMSSFAQFEDQQN
GARSARAEENIIATYDSIGNLMQEICKELPALKVYSFETQRENHAEVSRV
VSKLRNIHTGYSEFIYYTQRAFEMLFRLAYGGSHEEHKTYLITKTPVAFP
VQNYAVHKIANVDYKIENTVMCVMLRGALLPSMIVSKEIEEYSSHGYVTP
FALFKIKRDDLRDERDMQYVFDLDKSYFSARELDGKDLVFADPMNATGGS
LVTIVRYLQDLGVKPKSISCFHMISALKGAIRVVRSLENCTVYTLWMDPV
LNARAYIMPGLGDAGDRVNGVDVEDYPRNIIQLLADYGSNISGLYRSQLR
KIEETVLGSR
>gid:623  TP0595  adenylate kinase (adk)
MRFVFLGPPGAGKGTLAGEISGRCGVVHISTGGILRAAIQKQTALGKKVQ
KVVEVGGLVDDQTVTELVRERVSHEDVVSGFILDGFPRTVTQARCLEDIV
PIDYAVSIVVPDDVLVARLTGRRVCSACGSSYHVLFAQPKREGVCDRCRG
VLVVREDDKMSAILQRLTAYRAQAEPIVHFYSERGKLVSLNGAPPISDVV
LEFQERFAQSR
>gid:770  TP0734  purine nucleoside phosphorylase (deoD)
MSIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTG
TYKGVRVSVQGTGMGLPSHSIYVTELFQDYGVQKAIRVGTAGGLQEEVAL
KSVVCALGAATDSAINARRFSGMHFAPTASWSLLRTAVSVADEMGTGVQV
GNVISSDVFYDESGSWRLWARYGVLAVEMETAELYTLAAKFRREALSILT
ISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ
>gid:826  TP0788  T. pallidum predicted coding region TP0788
MRVRTFCFSLVCALGASTYLLWRGWLQLSLPAGSYGVMRSRSGGYHHALI
APGRFLWRWEPLLPSNAELFAFELKKQTVSVTVQDVLPAAKEYAQLLDQH
APFDWTLALSARVALKEAFLLDTVQRERITDQNSLERYVDTTAQAALTQV
SHDFIARCMADPALYERVHTQYGLATRELKRAIEKEIPHCAISEVVLSEV
HIPDMVLYHTAEQAYRAFEAKRSEHLSALAQQAAKRSALENFEMQRLTKW
GEFFQRYPSVIDFLNAIRQDGASTLETLKKGSTASHRAIPHEETTR
>gid:921  TP0885  deoxyuridine 5'-triphosphate nucleotidohydrolase (dut)
MIRVRAVVYPGASFPEYQTLGSSGADLRAFLPGGPLEVHPLGRVLVPTGV
CVELPVGLEMQIRPRSGLALEYGVTVLNSPGTIDADYRGEIRVLLVNLGL
AAFVVSHGDRIAQAVISSVLRVEYVRSGSISLTERGKGGYGSTGVL
>gid:1042  TP1001  T. pallidum predicted coding region TP1001
MQSYEGGVWLTCDIMGVSLFLVREHVVMWDLHRALCAGLLSVLLYGGCSS
ARDFVHVMKTAGNEVALVHYALQGDCIVFGFRGEVSDVVARVYRAEGVVS
EEMSDELLQSFTDEIPSALSRIAVPAAYQESVDAARERLSFFAVRFLQKP
HVGQQVVLRGSAQDVAHQKHDFVLPFEGINTQPARLEISEVRPLYGNKRS
EFVELLVVESGNLLGITITNVGGKGNRCDYHFPAAQVRVGERVVLHWRKQ
DPASCDELSAETVSAGSQACARARDFWGQERSIPGRNPNAIVVKESANGK
IQDALLFFNTHVKKGKAPTFRWAFPEIEAASRLALEQGAWLSTHEHFPLR
ESHFFQCDLTPAKSIALKRKRGAGRSAADCFVLKKATMGLPNQ
>gid:1048  TP1007  thymidylate synthase-complementing protein (thy1)
MTLRTLQAGVAVSIALDRVCFFCYNGAVAHCVVEAAEDILDRRFSVLDKG
FVRLIDYLGGDARIVQAARVSYGAGTRTARDDAALIDFLLRNKHTSPFEQ
VVLTFHVRAPIFVARQWMRHRTARISEVSSRYSLLSHDCYVPQETSVAVQ
STRNKQGRASEGISPEQQQEVRAAFEAQQKAACAAYDALIQKNIARELAR
INVPLSLYTEWYWQIDLHNLFHFLRLRASAHAQAEIRAYAEVIIEITRAV
APCATASFENHEKDGVQFSGREFAALKALLAGEGLSLEGKERARFEEKLR
SGLQQ
>gid:1049  TP1008  ribonucleoside-diphosphate reductase, subunit alpha (nrdA)
MHIIKRNGEPQPYMREKIIVAISAAFRSVQNPLAPEVPAIITDLAAEVER
QLFEMNRAGVPVHVEKIQDFVEKTLTKYNHSDEVKSFILYRDDRTKKRIA
REQIACCFTDSSVLGVLKEIQQDFPFPEYSLDALASKFLLFKKEVTDERR
SMQLLIKAAVELTAQEAPQWELIAARLLMLDFSLALGTSLEKLNIHSFYE
KITYLEEAGLYGVYIRTHYSRAEIEEAATYLECSRDKLFTYSSLDMILRR
YVIRTRAHVPLETPQEMFLGIALHLAMNETQDRMQWVKRFYTVLSKLQVT
VATPTLSNARKPFHQLSSCFVDTVPDSLDGIYRSIDNFSQVSKFGGGMGL
YFGKVRAVGAPIRGFQGAAGGILRWIKLANDTAVAVDQLGVRQGSVAVYL
DVWHKDIPEFLQLRTNNGDDRMKAHDVFPAVCYPDLFWKTVRDNLGASWY
LMCPHEILTVKGYALEDFYAEEWEKRYWDCVKDARISKRTIPIKELVRLV
LKSVVETGTPFAFYRDHANRANPNGHRGIIYCSNLCTEIAQNMSAINLVS
VKITEVDGQKVVVQTTRPGDFVVCNLASLVLSNIDLSDDKELREVVRVAV
RALDNVIDLTYYPVPYAQVTNAYYRAIGLGVSGYHHVLAQQGIDWESDEH
LAFADRIFERINRAAIEASMTIAREKGAYGCFTGSDWCTGAYFRKRGYVS
EDWQRLQREVATHGMRNGYLLAVAPTSSTSIIAGTTAGVDPIMKQYFLEE
KKGMLMPRVAPSLSQKTCPLYKSAHAVEQRWSIRAAGLRQRHIDQAQSVN
LYITTDFTLKQVLDLYVYAWEVGMKSLYYVRSQSLEIDLCGYCAS
>gid:1051  TP1010  nucleoside-diphosphate kinase (ndk)
MAFETTFVMLKPGVLQRRLVGEVLSRFERKGLVLTALRLLCVDTATAELH
YAEHREKPFYPSLIAYITSAPVVALAFKGENAISLVRTLCGSTRVEHAQP
GTIRGDFALRTTTNIVHASDSPESAARELALYFSAQDFVEWRDGNYDFF
>gid:1068  TP1027  uridine phosphorylase (udp)
MKLVYSTDCEYHIGLKASDIGHYVILPGDPARSEKIAQHFSHPHKVGHNR
EYVTYTGTLCETPVSVMSTGIGGPSTAIGVEELIHLGAHTFIRVGTSGGM
QPDILAGTVVIATGAIRFEGTSKEYAPVEFPAVPDFTVTAALKHAAEDVQ
VRHALGVVQCKDNFYGQHSPHTMPVHAELTQKWHAWIACNTLASEMESAA
LFVLGSVRRVRTGAVLLVIGNQTRRAQGLEDIQVHDTENAIRVAVEAVKL
LITQDSPR
>gid:1080  TP1039  adenine phosphoribosyltransferase (apt)
MRGIGRYHAPVDGHAALDRAIRKRIDFPKKGILYYDITGVLMNAAVFRYC
LDQMVEFYRDEHVTAVAAIESRGFIFAAPFADRMGIPLILVRKAGKLPGD
TYSCSYSLEYGKATVEVHKSDVVAGARVLLTDDLIATGGTLNAARTMLRA
GGAEVVGFFAVVGLPFLRYHELIGDLPVRTLIEYNQETSN


# Treponema pallidum subsp. pallidum SS14, SS14

>TPASS_0448 possible uracil phosphoribosyltransferase
MEGQTARRVITEAKFLDDCLTERDSYYLSKLDELYSSAMSSFAQFEDQQN
GARSARAEENIIATYDSIGNLMQEICKELPALKVYSFETQRENHAEVSRV
VSKLRNIHTGYSEFIYYTQRAFEMLFRLAYGGSHEEHKTYLITKTPVAFP
VQNYAVHKIANVDYKIENTVMCVMLRGALLPSMIVSKEIEEYSSHGYVTP
FALFKIKRDDLRDERDMQYVFDLDKSYFSARELDGKDLVFADPMNATGGS
LVTIVRYLQDLGVKPKSISCFHMISALKGAIRVVRSLENCTVYTLWMDPV
LNARAYIMPGLGDAGDRVNGVDVEDYPRNIIQLLADYGSNISGLYRSQLR
KIEETVLGSR
>TPASS_0788 hypothetical protein
MRVRTFCFSLVCALGASTYLLWRGWLQLSLPAGSYGVMRSRSGGYHHALI
APGRFLWRWEPLLPSNAELFAFELKKQTVSVTVQDVLPAAKEYAQLLDQH
APFDWTLALSARVALKEAFLLDTVQRERITDQNSLERYVDTTAQAALTQV
SHDFIARCMADPALYERVHTQYGLATRELKRAIEKEIPHCAISEVVLSEV
HIPDMVLYHTAEQAYRAFEAKRSEHLSALAQQAAKRSALENFEMQRLTKW
GEFFQRYPSVIDFLNAIRQDGASTLETLKKGSTASHRAIPHEETTR
>TPASS_0176 hypothetical protein
MTNVFKKNIRALRMRYQDIALTLERTHSNGIYAGTLTAHTGENIPFFRNN
RTLHSRYNPWIEAERTLPAQHASFFFVASGQVSTSVFS
>TPASS_0274 possible deoxycytidylate deaminase
MGQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGY
AGAPRGLLHCDEHGHQLRTVQHEDGTCTQHCVRTVHAEQNALCQAARLGI
GLEGATLYCTMTPCRTCAMLIINCGIVRVVAEKRYQTATESIMLFAQAQI
ALEHIYQNPAEYGTPS
>TPASS_1001 hypothetical protein
MQSYEGGVWLTCDIMGVSLFLVREHVVMWDLHRALCAGLLSVLLYGGCSS
ARDFVHVMKTAGNEVALVHYALQGDCIVFGFRGEVSDVVARVYRAEGVVS
EEMSDELLQSFTDEIPSALSRIAVPAAYQESVDAARERLSFFAVRFLQKP
HVGQQVVLRGSAQDVAHQKHDFVLPFEGINTQPARLEISEVRPLYGNKRS
EFVELLVVESGNLLGITITNVGGKGNRCDYHFPAAQVRVGERVVLHWRKQ
DPASCDELSAETVSAGSQACARARDFWGQERSIPGRNPNAIVVKESANGK
IQDALLFFNTHVKKGKAPTFRWAFPEIEAASRLALEQGAWLSTHEHFPLR
ESHFFQCDLTPAKSIALKRKRGAGRSAADCFVLKKATMGLPNQ
>TPASS_0045 possible adenosine deaminase
MKSLEYYRSQPKADVHTHLNLSMKYERYKQWSGVVIPNFPRKMRGLDEMH
EIIGEYTRPQCKTAQDVLNLFTMSIEDAIADNVVVMETSVDIGFITHYEE
NLDHFLCDLSDLHRRYKRNVTLHFELGISKIRERSFVEQWAEPMMRSGIF
ENIDLYGPEISEGIEDFIYIFKLAEKYHLKKKAHVGEFSDAQSVRHFVEI
FNLDEVQHGIGAATDENVLRFLAERKVRCNVCPTSNVMLNAVECLEKHPI
KKMMDAGVRVGLGTDDLLFFGKTNSEQLFDMVSCGLITELHAEALLAVR
>TPASS_0438 hypothetical protein
MRAVDFLRRATVCWYMRIYLASNNAHKHAEFSSLFPMHTILLPKDEGIDF
FSPEDGSTFFANARQKADALYDVVHAPVLADDSGLCVDALDGDPGVHSAR
FGAQHGVHTDTARMQLLLERMHGRQDRACSFVCVAVLKLGSVPLCVGRGV
CRGVLTTEMSGVEGFGYDPIFLLPHLGRTFAQLSIEEKNRVSHRALAALR
LAQVLAMMQLPRALRYELKLLRGARRMTRGGVLRPGAPCAQRKGQTAQTA
RRHKFYARARRCARRIHRA
>TPASS_0595 adk, adenylate kinase
MRFVFLGPPGAGKGTLAGEISGRCGVVHISTGGILRAAIQKQTALGKKVQ
KVVEVGGLVDDQTVTELVRERVSHEDVVSGFILDGFPRTVTQARCLEDIV
PIDYAVSIVVPDDVLVARLTGRRVCSACGSSYHVLFAQPKREGVCDRCRG
VLVVREDDKMSAILQRLTAYRAQAEPIVHFYSERGKLVSLNGAPPISDVV
LEFQERFAQSR
>TPASS_1039 apt, adenine phosphoribosyltransferase
MRGIGRYHAPVDGHAALDRAIRKRIDFPKKGILYYDITGVLMNAAVFRYC
LDQMVEFYRDEHVTAVAAIESRGFIFAAPFADRMGIPLILVRKAGKLPGD
TYSCSYSLEYGKATVEVHKSDVVAGARVLLTDDLIATGGTLNAARTMLRA
GGAEVVGFFAVVGLPFLRYHELIGDLPVRTLIEYNQETSN
>TPASS_0342 cmk, cytidylate kinase
MSNRCDVSGNKAVRIAVSGASGCGNTTVSALLAERLGLPLVNYTFRNIAR
ELGISLSEVLERARTDNHFDKAVDARQLCLAMRSSCVVGSRLAIWLVKDA
ALKVYLLASLKERVKRVLQREGGDVQDVERFTSMRDAEDMSRYKKLYRID
NTNYSFADLVLNTEGCDQETVVSIIIEMLRARGIAW
>TPASS_0264 deoC, deoxyribose-phosphate aldolase
MELNAYIDHTLLRPSASEAEVLRLCQEAQHYRFASVCVNPCHVALAAGAV
RGTAVRVCSVIGFPFGTHVTEVKCAEAQRALDDGAQELDMVVRIDKVCAG
EREVVEREIAQVAARCHARGAIVKVIVETALLDEMHIAFACSCVEAGHAD
FIKTSTGYASRGGTEGDIQCFKKYLKGETKIKASGGIRTRAQAQRFIELG
CARIGTSNGVAIMEERAS
>TPASS_0734 deoD, purine nucleoside phosphorylase
MSIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTG
TYKGVRVSVQGTGMGLPSHSIYVTELFQDYGVQKAIRVGTAGGLQEEVAL
KSVVCALGAATDSAINARRFSGMHFAPTASWSLLRTAVSVADEMGTGVQV
GNVISSDVFYDESGSWRLWARYGVLAVEMETAELYTLAAKFRREALSILT
ISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ
>TPASS_0885 dut, deoxyuridine 5'-triphosphate nucleotidohydrolase
MIRVRAVVYPGASFPEYQTLGSSGADLRAFLPGGPLEVHPLGRVLVPTGV
CVELPVGLEMQIRPRSGLALEYGVTVLNSPGTIDADYRGEIRVLLVNLGL
AAFVVSHGDRIAQAVISSVLRVEYVRSGSISLTERGKGGYGSTGVL
>TPASS_1010 ndk, nucleoside-diphosphate kinase
MAFETTFVMLKPGVLQRRLVGEVLSRFERKGLVLTALRLLCVDTATAELH
YAEHREKPFYPSLIAYITSAPVVALAFKGENAISLVRTLCGSTRVEHAQP
GTIRGDFALRTTTNIVHASDSPESAARELALYFSAQDFVEWRDGNYDFF
>TPASS_1008 nrdA, ribonucleoside-diphosphate reductase, subunit alpha
MHIIKRNGEPQPYMREKIIVAISAAFRSVQNPLAPEVPAIITDLAAEVER
QLFEMNRAGVPVHVEKIQDFVEKTLTKYNHSDEVKSFILYRDDRTKKRIA
REQIACCFTDSSVLGVLKEIQQDFPFPEYSLDALASKFLLFKKEVTDERR
SMQLLIKAAVELTAQEAPQWELIAARLLMLDFSLALGTSLEKLNIHSFYE
KITYLEEAGLYGVYIRTHYSRAEIEEAATYLECSRDKLFTYSSLDMILRR
YVIRTRAHVPLETPQEMFLGIALHLAMNETQDRMQWVKRFYTVLSKLQVT
VATPTLSNARKPFHQLSSCFVDTVPDSLDGIYRSIDNFSQVSKFGGGMGL
YFGKVRAVGAPIRGFQGAAGGILRWIKLANDTAVAVDQLGVRQGSVAVYL
DVWHKDIPEFLQLRTNNGDDRMKAHDVFPAVCYPDLFWKTVRDNLGASWY
LMCPHEILTVKGYALEDFYAEEWEKRYWDCVKDARISKRTIPIKELVRLV
LKSVVETGTPFAFYRDHANRANPNGHRGIIYCSNLCTEIAQNMSAINLVS
VKITEVDGQKVVVQTTRPGDFVVCNLASLVLSNIDLSDDKELREVVRVAV
RALDNVIDLTYYPVPYAQVTNAYYRAIGLGVSGYHHVLAQQGIDWESDEH
LAFADRIFERINRAAIEASMTIAREKGAYGCFTGSDWCTGAYFRKRGYVS
EDWQRLQREVATHGMRNGYLLAVAPTSSTSIIAGTTAGVDPIMKQYFLEE
KKGMLMPRVAPSLSQKTCPLYKSAHAVEQRWSIRAAGLRQRHIDQAQSVN
LYITTDFTLKQVLDLYVYAWEVGMKSLYYVRSQSLEIDLCGYCAS
>TPASS_0053 nrdB, ribonucleoside-diphosphate reductase, subunit beta
MMESSTILQRRALFNEAGDIELHKRRMVGGNTTNLNDFNNMKYPWVSKWY
RQAMNNFWIPEEINMSSDVQDYRNLSAIEKTAYDKILSFLIFLDSIQTAN
LPNIGQYITANEINLCLTIQAFQEAVHSQSYSYMLDTICSPEERNDILYQ
WKDDEHLLARNKFIGNLYNEFQDDKSVLALLKVAIANYVLEGIYFYSGFM
FFYNLGRNNKMPGSVQEIRYINRDENTHLWLFRSIIQELQKEEPQVFTAR
NVRLFRDMIREGCEQEIKWGDYVIGDQIPGLNRHMVADYIRYLGNLRCEN
LGFEPLYEGHRVEPESMSWVSQYSNANLIKTDFFEAKSTAYAKSSAMVDD
L
>TPASS_0170 pfs, protein Pfs
MTVGVFAALGEEVARVRECLGGVGTERAGLTFYVVSVGALQVVYVCGGVG
KVNAALCTQLLISEFGARVLINTGIAGALDERLCVFDVLVSVDAVQHDVD
VTAFGYQKGRIPRMDSVEWTANTALRYLVREAFDLCTRDPEWTEGACALS
GSGDPPSRVSRLVEGRVASGDLFVSDAQTRARIIREFGAHGVEMEGAAFA
HVASVNGVPFVIIRCISDGAGAEQDVSMSYKEFSTRAARRSALLTLRVLE
RLSALRTSVVASLFPMVVV
>TPASS_0294 prs, phosphoribosyl pyrophosphate synthetase
MRCSGFTDLAIVACPGGEHFADETIKHLTRVCERKFHQRMDRLTDRYGLD
SGSVIRDANFYRDLFSTELCAHDDVRRFNPPHFKVDAQFICFLNGELKTQ
INECIRGKDVFIFQDVENHQPVLVNNGKSKKIFSVNDHVMMLIVTIDAVR
HAGAGRVTLVLPTYPYSRQHKKCGREGLTAGLLGSVYEYLGVSHIVTLDL
HSREIENAFHRTRLENLHASYQIIRELAKIENLSDPDIPFVVVAPDSGAV
ERNKFYSSGLKKPLAMIYKVRDYSVVAQNAKQSNIVEINLLGDVEGKTAF
IADDMLGSGGTMLKAMEFLKSRGAKQVIAAVSLPFFTGNALELFDEAYEK
RYFSRIIGTNAVFHTQLSHKQWYTETDVSGLFARVIARIHHNQSLSSLLD
DRSIIERLLHARLSVAGTPRA
>TPASS_0305 pyrG, CTP synthase
MDPAFIFITGGVVSSLGKGIAAGAIGLLLKSRGISVVNQKFDPYLNGDPG
TMNPYQHGEVFVTQDGGETDLDLGHYERFTDVPSSRFNSTTAGSVYRAIL
DRERAGGYGGATVQVIPHVTDEIQARIRAAAATTGARVVITEIGGTVGDI
ESLPFIEAIRQIRRVLGKERCLFIHLGLVPYLPSCGEMKTKPLQHSVKEL
LGLGVQPDVILCRSERHITDAVREKLSLFCNVERRAIVENVTARSIYEVP
LLLEAEGLGALLCERLRLFDTCCGGQVARNLGAGGAQSAVLGAGGTVRTD
GGLHPAAGQGAEPDLTAWRAMVRALYYPRRELTVALVGKYVSLADAYLSV
SEALTAAGICHRARVDMRWIDAEEICSVQDAGHALADADALVIPGGFGVR
GIEGMICAVSHARVQNLPYLGICLGMQIAVIEFARNVLLLASAHSREFAV
DTPHPVVDLLPGCVDTPTGGSLRLGQYRCLLAEGSRARALYGRGEVWERH
RHRYGLNAAYRARFEASALRPVGVDSDCGAVEVVEHGEHPWFFGVQFHPE
FCSRPNRAHPLFRALVAAGLERKDSRS
>TPASS_0099 smbA, uridylate kinase
MVTVLSLGGSIVAPETPDIELLGRFVRSVQRYLYEDASRKLIVVSGGGAP
ARTYQNAYRALRRSLSSPACAKPAHEGDNQEDRELYATAEHVELDWIGIM
ATRLNAQLLKSLFGILCPNPVVYDPTAANVFSGQVLVAAGWKPGFSTDTD
AVLLAERYSAKTVINLSDVAHVYTGDPRSDKDAKALTSLSWDDFLLLVDK
EWVPGSHVPFDPVASVRAKKSGIQVICATGRDLPNLERILNRQEFVGTTI
G
>TPASS_1007 thyX, thymidylate synthase-complementing protein
MTLRTLQAGVAVSIALDRVCFFCYNGAVAHCVVEAAEDILDRRFSVLDKG
FVRLIDYLGGDARIVQAARVSYGAGTRTARDDAALIDFLLRNKHTSPFEQ
VVLTFHVRAPIFVARQWMRHRTARISEVSSRYSLLSHDCYVPQETSVAVQ
STRNKQGRASEGISPEQQQEVRAAFEAQQKAACAAYDALIQKNIARELAR
INVPLSLYTEWYWQIDLHNLFHFLRLRASAHAQAEIRAYAEVIIEITRAV
APCATASFENHEKDGVQFSGREFAALKALLAGEGLSLEGKERARFEEKLR
SGLQQ
>TPASS_0354 tmk, thymidylate kinase
MNILHNFVVFEGIDGTGTSTQLRALERHFQARKDMVFTQEPTGGEIGTLI
RDVLQKRVIMSSKALGLLFAADRHEHLEGAGGINDCLAEGKIVLCDRYVF
SSLVYQGMAVSGSFAYELNKEFPLPEVVFYFDAPIEVCVERITARGLQTE
LYEYTSFQEKARKGYETIFRKCRHLYPAMKVIEIDAREEIEVVHERILHH
LREYRRLK
>TPASS_1027 udp, uridine phosphorylase
MKLVYSTDCEYHIGLKASDIGHYVILPGDPARSEKIAQHFSHPHKVGHNR
EYVTYTGTLCETPVSVMSTGIGGPSTAIGVEELIHLGAHTFIRVGTSGGM
QPDILAGTVVIATGAIRFEGTSKEYAPVEFPAVPDFTVTAALKHAAEDVQ
VRHALGVVQCKDNFYGQHSPHTMPVHAELTQKWHAWIACNTLASEMESAA
LFVLGSVRRVRTGAVLLVIGNQTRRAQGLEDIQVHDTENAIRVAVEAVKL
LITQDSPR
>TPASS_0104 ushA, 5'-nucleotidase
MKRFIPHRVIHAVCIGLALVGCRKLDSRAGDFELTIIHINDHHSHLEPEP
LELAVAGERLRAAVGGYAALVHEIQRLRAESKNALVLHAGDALIGTLYST
LFRGRADAVLMNHAGFDFFTLGNHEFDNGNEGLKEFLHYLEVPVLSANVV
PNAASTLHGLWKPSAIVERAGERIGVIGLDTVKKTVESSSPGKDINFIDE
IEAVRRATVEMQQQGVNKIILLSHAGFEKNCEIAQNISGIDVIVSGDTHY
LLGDESLGRLGLPVVGEYPRKIMSPAGEPVYVVEAWEYGKCLGELNVVFD
RTGVITSAVGMPRFLLHTNTLQKKGADRKNYPLEEAEREALLVALRMTPE
IIFAQENDQIISVLEEFKKEKEALGAQAIGVITGASMRGGSVHRVPDAQN
PQGSVATRFVAETMLSDIQSFGAGKVDCVIQNAGGARSNIQPGEITYNDA
YTLLPFSNTLVLVDVSGAELKQIIEDALQFALGDGSTGAFPYGAGVRYEA
RQEPDEHGKRVIKLEVQKKDGAWVPVDERAPYRLGVNSYIARGKDGYKTL
GEIVSTRGAEDTYLRDAESLIKFLRAHKNFRAYTDSNVIFRLK