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# Treponema denticola ATCC 35405

>TDE0439 hypothetical protein
MKKMIIVFFCMLFISVNSFAEFVISPTLGASNVFSTDVFPPTVYIGGLSH
KEKSSLSWTPMNFGILLGTVKEKGFTFLFSVDALFIGNVNANYKEFVRDT
EVLNFKAKAKIGGGAVAQGNFLFGYTYKGVPNLYLTFASGLTLGGGVNTI
KEISTSGITVPNINVSLKTANFGIPLYFSASYYFTDKIGINVSFLNSFCA
GWQWYNDKSPLPYLGTGYGPETPAFVNVFTFKIGPTFKL
>TDE1499 adenylosuccinate lyase, putative
METRSIFKNISPIDHRYSLPQGGLYDELSVFLSEEAGIVYCAMAEMAIVK
AHLKIAEEKKGSLLPKLSGELEKTLDDIALNIDPSEVYEEEHKTQHNIRA
LVNVLKKKVPENTAPLVHLGATSADILDTAFSMRIRDAVIKVIIPLLKKT
ELLLCDIAEREAETPQVGRTHGQHAVPITFGYAVSEYVARLGKSILKMED
LVKDLRGKFAGAVGAYNAASLIVSDPMRFEKIYLDYLGLKPSEYSHQLVE
PEYMLRLLLEANIAFGIIANLADDLRNLQRTEIGEVFEYFSATQVGSSTM
PQKRNPWNSEHVKSLWKAFSPRIMSFYMDQISEHQRDLSNSASQRFIADY
LTGLALAFNRMNSILKGLQADRENMLKNLLQGGGKVRGGVMAEPAYILLA
ECGVSDAHEVIRKITLAAENQKISFYEALKAEEKVFALVTERLKELNFDK
PEEFFANPERYRGLANVKAKALAEKYKALM
>TDE0687 phosphoribosylaminoimidazole carboxylase, PurE protein
MRPLVIILMGSSSDMGHAEKIASELKTFGIEYAIRIGSAHKTAEHVVSML
KEYEALDRPKLYITIAGRSNALSGFVDGFVKGATIACPPPSDSFAGADIY
SSLRMPSGISPALVLEPKNAALLAARIFSLYDKEIADSVKSYMESNAQKI
IEDDSKLKR
>TDE0105 MTA/SAH nucleosidase
MKIGIFGAEEQEVKLLKKHLVGEIRKIAGLSFFTGTIMGKDVVLVCSGIG
KVNAALCCQILISEFKVDAVINTGAAGGLLEGINVFDMVVSTDAVQHDVD
ATAFGHPIGQVPMTKSPFWPADKKLKTLALKAFKAMQKESDDEHIKNLKL
IEGRIASGDTFVSDKKLRERIIKEFNPACVEMEGAAAAQVCCINKIHFLI
LRSISDTAGKDKAAKISYEVFSAQAAKDSSLLVLQMLKML
>TDE1803 conserved hypothetical protein
MENYENRIVAFIDILGFKDLIKKSENNPYQINELLEILKYIKAWDTQGQN
KWDTNVIAVEEDAQTKGLEKFDISGITACTCFSDSIVVSVQCENELINEK
ASTLIGNLSKIGAKLLQAGILIRGAMTVGNLIHTNDGIIMGPAIIEAYLL
ESNYAKNPRIILSDKLIGKLNYPLKRKSDRYPYHQYINRFKDGCAGFHQM
QFFQVMQSEVNEQNKLKYDLDVIRKRLIDGLDMSFSKPEVFLKYQWLMNQ
YNELVINEDNVKKPIYDVNLADSHLNIHYSPIDQVRNKEDT
>TDE1612 phosphoribosyl transferase domain protein
MGKVIMGAEALDGYLTEDDLRHLNEMNALYQEAIENFAVLEKENGEKKKK
AKDEVIRLYTEMGHLMQNICKDIPQLKVFSFDTEHENHAEASRVIAKLRS
IKTEHSEFLYYTQRSFEMLFKLAYKGHQKDKKNYLVVKTPVTNPVQNYAV
HKITDIDHKIENTVMCVMLRGALLPSMILSKEIEEYSSHGYVTPFALFKI
KRDDSRKEDDMQYILDLDKSYFNLKDLDGKDLIFADPMNATGGSLVTVVK
HLKKLGVKPKSISCFHVISALKGALRIVRALDNCTLYTLWMDPALNASAY
IMPGLGDAGDRINGTDTDETPRNIIQLLADYGSNIAGLYRSQLRQIEKTV
LGN
>TDE0594 cysteine protease domain, YopT-type
MKKFLMITITVCLLAGGVNAFAYGINSFTVYDAQDNIVHKITAKSKVNAL
YLLFQESLQIAADEAFFMELPKDAQVLYRYVLSYNYGDDEQYFSFIVYKN
YPLCRIPQLQEKEDIPKELTWKLFKYAYEIASRPAEVKKQLSYSAKNSYI
RIYDDKGSLLLFTAGEKILDMFDTLFGKDIAEIEIEERNLKSLFTAESIH
DGREVLVHYSFMDDDKIMKLYIYKDTKEMNITTDTGVLKVNLSEEAYRIL
SSPKSFQKEFEKRR
>TDE0202 conserved domain protein
MKTSRIKFAVRLMFFLFCVSAVFSESGDIKQNIPVTSMPPKWEPLFPSAL
WVKNIPIKQEVLIQTVKTKEEMDASLKFDESKLQSVLLNNDIFALYGKPG
AYTMGILGRYSPEEIEPIMNEFIITYDEVNKERGIIPAFYLIYGTCWPEG
EIGLLRLSTVKKYIEFAAERGWYVFIDHQIGKYTVEQAMNAILPFLKYPN
VHLALDPEWRTTQPMRVIGSVTGDEINKAQEMMDKYIKENNITGRRMLVI
HQFNSIMIKKRANVRSDYERVQLIHCADGFGSPQLKKDSYAYNALAQNIP
LKSFKLFSKPTVAGAGYDQPMMTPDEVFNLNPRPYLIMYQ
>TDE0267 HAM1 protein
MDLRFVTKNKFKVDEVQKLLTSINVIHCPIEIKEIQTESIDEIVNDKVLK
AFNKIGRPLFIEHTSLYLGGMNGFPGGLTQIFWDKLQADKFSEIVSKMSD
QTVEAKTVIGYCTGKKIYKFEGVIKGKISDLPKGSKDFQWDCVFIPDGHS
QTFAEMGEQKNIISMRKIAFDKFYDFLKDKR
>TDE2613 conserved hypothetical protein
MIKIALGISIILIFFLLGLVIGKYKERSLNLKRVNEARKDAVKRSRAVLN
GQLSEQLAPFFPDFPANPTEIRFIGQPVDYIAFNGASQGTITDISFIEIK
TGSAALSPVERALKDAIEKKKIKYIEYRADLNKK
>TDE2193 deoxycytidylate deaminase, putative
MVDTKEKYKRPSWDEYFMDVCRAIAKRATCDRGRSGCVIARDHQILVTGY
VGAPTGLPHCDDVGHQFKKLQHEDGSVTQHCVRTVHAEQNAICQAAKRGI
SIDGATLYCKMTPCRTCAMLIINCGIVRVVAEKRYHDSADTIEMFKKAGI
ILEHISDSLEEYKGQ
>TDE0901 conserved hypothetical protein
MCLICKRIEMIKNGNNPYYVKELETGYVVIGDHQHFKGYTLFLCKEHKTE
IFQLENDFKMKFLEEMSIIAEAVYKAFHAEKMNYELLGNGDTHLHWHLFP
RINGDLEGHGLHGKGPVWWYPIDKMYDAANRPTSEELYDMKVKLLEHLKK
A
>TDE2085 amino acid kinase family protein
MVTVLSVGGSIVAPDKPDFDFLDKFSKTIRNWLLQDSSRKIIMVIGGGAP
ARDYQNAYRKVCDLRKAPAKNDEADWIGIMATRLNAQLVKAVFEDLCPNP
VVYDPTTVDMFGGQILVAAGWKPGFSTDNDAVVLAERFSGNLVVNLSNIA
KVYTDDPKKNPEARPIDSISWEDFIKIVGTEWVPGKNTPFDPIASQRAQK
AGIKVICAAGKDIENLENILNGKDFKGTVIG
>TDE0870 phosphatase/nucleotidase
MKKRLTFILISVFVIFSFTSCLETRVKESGVRSKREMLATGKQSDEVKLT
HAVIRKGEAGKDNVTLTFGVTGDVHGRLYPFEYAVCEEVPGAGFSKTFTL
AQELRKENPNTVLIDVGDTVQDNNAELFNDLETHPMIQALNYMNYDIWVL
GNHEFNFEKEFLARNIRNFNGAVLSANIRNEKDKSFFVLPYQLLEVEGVR
IAVVGLIPPHIPMWESSSPSHFKGLTFEEPLDAARRTVDSLKGQYDVLVG
AFHLGRNAEYGSTGGVIEIAKQIPEFDIIFGGHEHARYASIVDGADGDKT
WIIEPGAYGWALAVGEIKVKKEKDKWKVVSVKAENRETKNVLPNKPMEEE
FKFVHQTSLSDANTVIGNITEDFIKRVDYITGEDKVTTMPTIQLEDTALI
DLINNVQLYYTKADVSSAAAFRSDMNLKAGLFKKKDVAFIYKYANTLMGV
NITGENLLKYMEWSASYYNTTKKGDVTISFDPKIRSYNYDMFEGLTYDID
ISQAPENRIKNARIKGKPIDPKKNYKLAVNNYRFGTLTKLGLISEKDVYY
DSYMKMQDAGRIRDLIVKYVKEVSKGVIKPVTNNNWKIIGFDPDVKGKEE
ILNKIRSGEIKIPKSEDGRTPNVKSINIYELK
>TDE0311 thymidylate synthase-complementing family protein
MDKEFKVLDKGFIRLVDYMGTDARIVQSARVSYGEGTKTVREDAALIDYL
LRNKHTSPFEQVVFTFHVKLPIFVARQWIRHRTARLNEISGRYSILKAEF
YVPAGKDIALQSSDNKQGRMNEAVPQDLQNEVITSLQKQQEEIYAGYSKL
LDKNIARELARINLPLSTYTEWYWQIDLHNLFHFLRLRMDAHAQKEIRDY
AEVMFEICKTVTPLACASFERHEKNGVNFSAEELEAIRNLIAGKDSGLKG
KELERFNEKLKSGRQV
>TDE0009 hypothetical protein
MAIITISRKIASFGDETAIELAKLLNYNFIDRKSLEKDLLAKGISEVQLK
KYDERKPGFWASLSRERDSYFDYLREAVYEHASSGNSIFIGRGGFAILRN
VPGLYSVRLVAADDIRISRLMKEFNYSEKEARALMEESDNNRDGFHKNFF
NTVNEDSSEYNLVINTGHISHLQAAEIIKYGLEKTISKEDAALGDKRLKE
LLLAQKIVNHISFDLKLQIYFLEADISEHEIILHGVADNAGLIQKAIDVA
QEMAGGRKVSSAISMVNEYKPFP
>TDE2271 HAM1 protein
MKIYLASGNVNKKREVQELLPSHTIVLPKDEGIEFDPEETGSTFFENAMI
KAKALYHIVKAPVLADDSGLCVDFLNGAPGIHSARYGSIEGEHVSAEAGI
NKVLSELKGVKDRSARFACCMVCLLDENRFYSVQETCEGHITEAPSGSGG
FGYDPIFFVEKFGKTFAELTSEQKNSISHRGRALFSISRFIKGS
>TDE0423 hypothetical protein
MKKDKLKLIFILILAALLFSCSKELKEQKPEETKVESSAKIEPKENEFLS
KPEYNTHVKSPEQIKELEEKYKRSEAYEEKLKQLRTELDKKEDILRYKCP
VFMSIDNLAQQKAPALYSHADNLDFIHFYEIKKDGEFCYCKYKAPTQNGG
ILDYQVTYKWYNIEQMYLPLSYDLLSETNMVKINDELIENQVHGSIYSME
NDEKKDEMIKLFEDYENTQYPLYLEVANTDWKTGAKTEGYKQYDMKILDY
VKGNFTNSGYDEYFVMFYRDHPNPEIDDQFIERVRCFIVSEDKIINDYYI
SNSGGFFYPGLRYDKLSEVKDFGFKFSQGWIADFNQNGINEIYLAALFDI
YGGGLLIIEYNDGSFVSGYVYDNRYDIVGIDWYKKMIIIKDKSRSGEWID
DYQWNDTLKEFILLKRKYRDD
>TDE0188 adenosine/AMP deaminase family protein
MRDFDYYKKQPKADTHNHLNLSMEYSDYKKWAGFEIPNFPRKMNGLDEMH
EIIGQYTRPACTTAQHVIDLIEMSIMTAIKDNVVCIEGSVDIGFIKQFNE
NLDAFLEGISGIVKKYKNKIKIIPELGISKTIDQSFLKQWIEPMISSKVF
KNIDLYGPEVSEGIEQCVYIFKLAEKYGLKKKAHVGEFSDAASVKYFVEM
FNLDEVQHGIGAAQNDKVLQFLADRKIRCNVCPQSNIMLGAAKDLKSHPL
RKMMDAGVPISIGTDDILFFGKTNSEQFYDLVSEKVITEEEADQLMAIR
>TDE2107 dihydroorotase, putative
MIDSHVHLRDGLLSDKETIAHALALACPAGFTAFFDMPNTNPPLTNAEAV
LERFALAEKSIKQAGVSAFYGIYGGLTSDIAQIEKMVLFYKKYFPKIVGF
KMFAGHSTGNMGIVEKEDQRKVYAALKKFDYRGILAVHCEKESLMNNSIF
DIENPITHSLARPPIAETESIKDQIELMQSEDFKGHLHVCHISTKEGIRL
VAEAKKSGLSISCGATAHHALLNIDSYKKSGIFVKMNPPLREKEEQEAVF
NALISGGIDWIESDHAPHTYEDKKKGASGIPGFAGSLILLKELRKAGCSE
KRLDELCGKAVNHIFKLDLSYKVPSNTEIDASLPSLRSGYPFDAFEFFGI
SKFSFLNFIVTLTICTIAYIL
>TDE2257 5'-nucleotidase family protein
MKNSKFFKAVGFVVIVLILAAAFTGCETESHDVSGQYAGIEANAPANRID
ILLFNDFHGNVAEDTRPGKGKNAGMAKMIGYVRTAGMENPNTIVVAGGDN
YQGTAISNLTYGAPVSAMMRAMDVKVCAVGNHEFDWGSNRMTKWQKDGNF
TFLAANIVEKKTGKPVSWAKPYAIIKKGNYKIAFIGLAHPDTAVLTSAEH
VSGLEFTDPVKTGQEWVNYLLAGKAKEGKPDAIIALTHIDSFQEDGKISG
NAVKLTEIKGLDAVLSAHSHRTVSGNVNGIPILQAYCYGRAVGKLSITFG
SENKIAKIESAVDEIYKHKDSLIEDEKGKALFTKYDTELKPIMGEVIGVA
EGEFTHERSEKGSNTLLGAWAAEVQRQLGKADIAIQNGGGLRRTLAAGNI
TVGDLYEIMPFDNYLVVFDLPGSEIKKAIDHGIMNPNITDGQFAGLRVEY
DGRKPFENRITKITLMDGTPLDMNKKYRVVVNSFMFTGGDSYDFSKATNS
AESVSIRDALIDAIKKAKTIKPIPVDYIKDISK
>TDE2242 antigen, putative
MKKTLIFILMILVLIVSSCNLFLKEEYGELIVSFDGTLPDGARALDSNGL
PVLSSSPMKINIIREDGYTITRELSAEEPKSLVELVPVGEKIEIIVTAIN
PSGQWSGRAFHTVVSGQNHVKVLLNKNISGLNNLLFTQTKDLFSTPPYNL
TLYMNGKEINAHPSQSEYSFGRDSLGRLYISVNEGNSHVSRYTSEGELLN
HVMESIVYFACDYTTRKMYGINGSGGVYEIDENFSISSLTPPLNLSHYDG
AAAIDNNLFVWICDDGSNPLKIQAKNLDGSHPSETEIKDHIKITDCKESE
VKDMFIRGKYVYVLFNTMNDELTGNSRNLYSLGGVVRYNINNLTAPPVKI
GFSNSVSFENSLLKNYDYSANFYGAVKVIGFDEENIYIADDGFDAADTPA
GARIVKNRNRIAALNIATNALSFSDAGPAKWYNEWKEWRTPNTKMIVWES
LYDGSSRSGMSYYQVEKGDENLLGANSFITSDVSNPTGVLYSDVFCYDSA
GNFYVSGKDNSDEKLYRYVLKDDGNYETDGEKDISEKPTTIAVSVSSVPD
DAGKTILFYYFESGNGHNIGRLAWYTDDFANAVQRRNITLNDLDQNDTVT
AMTANKDGIFVAVKTVTGKDSPNEKYKITVKKYAHQPLGSPAIISAVETV
TVVDETSTNYPNVVVPPSHWTAEQANAYINEDLNALYISDGVLYGLTTNQ
KGYIKDIFSKATEVFIGGKLLKIGNTKSLGSYVVVLYKNDGLRPATSGEF
APYRFIAVKPKKLVIASDGYYGKGTAPRNKNKVFVFDIGNWAHPDETVTQ
TRINLSKQLGYSGNSFIWTIE
>TDE0015 lipoprotein, putative
MKFRRYIFILIPMIFIGFTACNNRPIFAAIEQEVELKEFSVGGNVLSLVA
TDTMVYASNLAGVYSKSKNYDGPWSKILPAERTQKLAKNAANVFASFVTG
PVKFYDESTKTWSAVSGSDDIHVIAGDTTVFGYDSNQKKVFKIGIAGINN
PIATGEVNFLYAAGNYVVVQSKNSAKLYKADASPAVEISNLPSGVKGMCS
TGNPNEVFVLAGSTVYYINGGTWNNKISISKSPVSISYFKERKTILLGCD
KGYTEIQLDNAHTTDLSKAKQLNPGNSGSTTPPGSYSQYQTTLGSYYTYP
VLGVERGNAGSGKYAVFMGIYSGTITRNTGLWGFYSDKKREWNRE
>TDE1112 adk, adenylate kinase
MNCIFLGPPGAGKGTLAFEVSKSYKIPHISTGDLFRAAIKEQTDLGKKVK
AVIDSGALVSDDLTIALVKERLERDDTKKGFILDGFPRTIAQADALEDIV
KIDSVINFDISDDEVIKRLSGRRVCSSCGQSFHIEFVKPKKEGICDSCSG
DLMIRPDDKIEAIQKRLETYRNQTAPLIDYYTKKDLIVNIDARPASEKVL
ASFKVKFPH
>TDE1684 apt, adenine phosphoribosyltransferase
MTIAKIRCRLFIMKDKIIDAAIRRVPDFPKKGILFYDITGILVNPEVFSY
CLDKMTEMYKDKKVDAVAAIEARGFIFAAPFAYKMGIPLILIRKKGKLPG
ETYSASYDLEYGQASVEVHKTDVVKGQKVLLLDDLIATGGTLNAARSILE
EGGAKVVGFCGVVGLPFLNYSKVLGDLPVKTLIEYDSEKI
>TDE1931 cdd, cytidine deaminase
MEISSQLENLFKTALEAAKKAYAPYSNFHVGAAILLEDGSIVTGVNIENR
SYGLTNCAERTAIFKAVSEGKTDFKAIAIATPDADYPVSPCGACRQVISE
FMGGDTPVIFGSSLDNVVLTDVKGIYPFDALHELKK
>TDE1087 cmk, cytidylate kinase
MKKTAFKIPEGKELRIAISGPSGCGNTTVSTLTAKTLNLPCINYTFKNIA
KELNISFEEVLRRAQEDFSFDKTVDKKQIELAEASSCVLGSRLAIWLLNQ
ADLRVYLRASIEVRAKRIQKREGGDIEKIKADTDLRDMEDTRRYKELYGI
DNTKYEKADLIIDTDNLTPEKIVKKILSELYSRGLLI
>TDE0448 deoC, deoxyribose-phosphate aldolase
MELNKYIDHTLLKPTASEKDIIKICNEAKEYHFASVCVNPCNVSLVRKEL
KGSDVKVCSVISFPFGASSTEVKVEEAKKAIEAGAEEIDMVINVGKLLEG
DLEYTQNEVSAITKACHEKNVLLKVIVETCYLEEKNIADICAIIEKAGAD
FIKTSTGYGSRGASVEDIKLFKKYLKKDTKIKASGGVRTREDAETYIGLG
CSRIGASSGIAIVTGK
>TDE0463 deoD, purine nucleoside phosphorylase
MSVHIAAKQGEIADKILLPGDPLRAEFVANNFLENPQCYNKVRGMLGFTG
TYKGVRVSVQGTGMGQPSFSIYANELFNEYGVQRAIRIGTAGALQKDMGL
RDVVLAMAASTDSGINTHRFRGCHYAPTADWSLLKNAYDHAQKMGIKPLV
GSIASSDVFYDDLETWKMWAAYGVLAVEMEAAELYTLAAKYKRQALAVLT
ISDNIVTQEQTSAEERQTTFKTMMEIALEAIIA
>TDE1042 dut, deoxyuridine 5'triphosphate nucleotidohydrolase
MEVFTKLKEGALLPEYKTSGSAGADLRALIEEPIILKPMQRCLIPTGLSV
ELPKGIELQVRPRSGLALKHGITVLNTPGTVDSDYRGELAVLLINLGNED
FKIENGDRIAQAVIAQAIQADFLQKDELSNTERGAGGYGSTGIA
>TDE0019 fhs, formate--tetrahydrofolate ligase
MKTDIEIAREAKLKKIAEIADGLGIHDDNVIPYGKYIAKVPYSVIDDAKV
KKNNLILVTAITPTKAGIGKTTVSIGLALGLNKIGKKAVAALREPSLGPC
FGMKGGAAGGGYAQVLPMEDINLHFTGDFHAITSAHNMISALFDNYIFRA
QGTPKAIKTVLWKRVLDVNDRNLRQVVTGLGEGNGVVMESGFDITPASEI
MAIFCLAKDIEDLRRRIENIILGYDTENNAVKVKDLGIAGSIVVLLKNAI
NPNLVQTTENTPAFIHGGPFANIAHGCNSVIATKTALTYGEYVITEAGFA
ADLGAEKFFDIKCRKAGLNPKLTIIAATTGGLKMHGDVPEKEISKPNAEA
LKKGLANLDKHIENMKKFGQTVVVALNRYGYDIDSELELVRKHCEAQGVG
FAVNNAFVEGGKGAVELAELVVKTIETNPSKPLKFVYEDKDSIKTKIGKI
CKEIYGAADVTYSGAADKMIKKIEEAGMADFPVCVAKTQYSFSSDPKLYG
VPTGFEMNVRDIVLNSGSEMIVAIMGDMMRMPGLPKDPQAVRIDLVNGNV
EGLS
>TDE1718 guaA, GMP synthase
MKKKPLSAKIVFMKITEKILIVDFGGQYNQLIARRVRDLNVYSDIVPASK
ALDYIRENKPIGIIFTGGPNSVYEEKAPLPPKEIFNLNIPILGICYGMQA
MAHCLGGKVEKSLKREFGKTLTKFDTGIPLFKNIKDKSSVWMSHVDCVSR
LPEGFVSAAQTANTKNAAMANKEKKLYGIQFHAEVEHSEEGQNIIKNFLY
NVCGAKGDWNMKSFLAEAIKDVQNTVKDGKVLLALSGGVDSSVLAALLNR
AVGKNLTCIFVDHGLMRKNEGDEVEAAFRDTPMNFIRVNAESRFLGKLKG
VSDPEKKRKIIGEEFIRVFEEEAEKIGTVDFLAQGTIYADVVESGTKGSA
VIKSHHNVGGLPDHISFKSLIEPLKTLFKDEIRNLGTELGLPDYLVHRQP
FPGPGLAIRIMGEITEEKLDILREADAIWRSELEHADIKKDLSQYFAVLT
STKTVGVMGDFRTYDYTLALRAVKTSDFMSADWVRIPYEVLDKVSSRIIN
EVKGINRIVYDITSKPPATIEWE
>TDE0341 nrdA, ribonucleoside-diphosphate reductase, alpha subunit
MQIIKRNGETKNYEPEKIEGAIRSAFKSVENSPHTDLDTIIPPLVKEIEE
DILELTKNGSLVQVETIQDLVEKTLIEHNYYAEVKNFILYRVGRTKRRDS
RQMISRFFDTIEIQSVLTEIQNDFTSDEYSLNLLAHKFLSFRKENMSETE
SLAMLIKASVELTAQDAPDWEFIAARLLMLQFKLKLKTELEKRQIHSFYE
KIKYLENEGLYGTYICEAYSRDELEEAASFINEERNKLFTYSALDLLLRR
YVIHTHSNIVLESPQEMFLGIALHLAMKEKLKRLEWVRRFYDMTSTLKVT
MATPTLSNARKPYHQLSSCFIDTVPDSLDGIYRSIDNFAKVSKFGGGMGL
YFGKVRAVGSPIRGFMGAAGGIIRWIKLANDTAVAVDQLGVRQGSVAVYL
DVWHKDIPEFLQLRTNNGDDRMKAHDVFPAVCYPDLFWKTVRDDINSSWH
LMCPHEILKTKGYALEDFYGEEWEKRYKDCVADSRINKREIPIKELVRLI
LKSAVETGTPFAFNRDHANKTNTNPHKGMIYCSNLCTEISQNMSGIKHKN
IEIKTEDGDTVVATTTIPGDFVVCNLASLVLGNIDVNDEQEIDTIVSSAV
RALDNVIDLNFYPIPYAQITNSRYRSIGLGASGYHHALAKNGIAWESEEH
LNFADKVFERINYAAIKASSQIAKEKGSYSYFEGSDWQTGEYFKKRNYVD
ENWKALTEEVKSNGMRNAYLLAVAPTSSTSIIAGTTAGVDPIMNKYFLEE
KKGSLMPRVAPSLSPETYWLYKNAHHIEQGWSIRAAGLRQRHIDQAQSVN
LYITNEFTFSKVLSLYVKAWEEGLKSIYYVRSRSLEVEECESCSS
>TDE0335 nrdB, ribonucleoside-diphosphate reductase, beta subunit
MITEKTILPHKALFNENGDIETHKRKMIGGNTTNLNDFNNMKYSWASDWY
RQAMNNFWIPEEINMTTDVQDYRKLSIPEKTAYDKILSFLIFLDSIQTAN
LPNVGQYVTANEVNLCLTIQAFQEAVHSQSYSYMLDTICSPEERTEILYQ
WKDDEHLLRRNKFIGDLYNEFQSDKSALAFLKVCVANYILEGIYFYSGFM
FFYNLGRNNKMPGSVQEIRYINRDENTHLWLFRSMIQELQKEEPQLFTPQ
NVELFRAMIKEGCEQEIAWGDYVIGNDIPGLNSQMITDYIQYLGNLRCEN
LGFAPIYDGHREEPQSMSWASQYSNANLIKTDFFEAKSTAYAKSSAMVDD
L
>TDE1331 nrdD, anaerobic ribonucleoside-triphosphate reductase
MEEKTTNQTVFPEWKSFLGTMEKAKPEILRSVVKRSGEIEAYNRKKIEQA
INKAITAVEGSPNDEKAVFLTDKVEEKLKNIMASRYAHSIPAIEEIQDVV
ELVLIEQQEARLAKAYILYRAKREAVRDAESLMLNINSTMDGYLSQSDWR
VKENANVNFSLGGLILHNSGTITANYWLKNIYTPAIAEAHITAAFHIHDL
SMFSGYCAGWSLRQLIHEGLGGVPDKITSKPPKHLSTLIQQIVNFLGIMQ
NEWAGAQAFSSFDTYLAPFVKKDKMSEANVKQCLQSFVYGVNTPSRWGSQ
APFTNITLDWVCPPDLANQKAVVGGETQDFTYGDCQKEMDMINKLFIELM
LEGDAAGRGFQYPIPTYNITSDFDWSSPNAKLLFEMTARYGTPYFQNFIN
SDLNPGDVRSMCCRLQLDKRELRKRGGGLFGSDEFTGSIGVVTINMPQIG
YLSKTEKDYFDRLDYLMDIAKQSLEIKRKVIEKLLEGGLFPYTKRYLHHL
NNHFSTIGICGMNESCLNFLGEDIVSPRGKAFAEKVLTYMRNRLADFQEE
TGSLFNLEATPAESTSYRLARHDKNQFPDIISSGDAEPYYTNSSQLPVAY
TTDVFEALDHQESLQRKYTGGTVFHIFLGESIKDWESCRDLVKAVANNYR
IPYFSISPTFSICPVHGYLEGEHFECPYCKREKQAKLELKLAELEKEKAE
VLSVSSKI
>TDE2191 pdp, pyrimidine-nucleoside phosphorylase
MRATDIIMKKRGIKGQAIEPLNRKEIEFIVNSYVRGEIPEYQISAWLMAV
YFNGMTFEETAILTDVMLHSGKVMDLSSLEGPFVDKHSTGGVGDKLSLPL
APIVAANGVKVPMMSGRALGHTGGTLDKLEAVTGYRTNLTEAEFRNFIEK
TGFAMTGQTKEIVPADRLLYAMRDVTATVESVPLITSSILSKKVAEGSEA
LVFDVKCGKGAFMKTLSDAKALAVSLVGTAKAMGKKARALITNMNEPLGT
MAGNFLEIEETIDILKGQGPADSTELTLQLAAHMLVLGGKAKTEEEGLSL
AKEAVSSGKALDLFIKNIELQGGNPKTLMAEYKTRRSKFFEELKAERDGF
IESINAFEVGMAGVNLGVGRNKTTDPVCPDAGVEILKHKGDSVKKGDLIM
RVYGKDSASVSASMPLLKNAIEYSDKAPQKNKLIFKIIKQEEL
>TDE2723 prs, phosphoribosyl pyrophosphate synthetase
MNYLESNNLAIIACPGGEEFANLTIKNLKHIYARKLYQQSEKLAKRYNTS
SEDMIQKFNFYSDLFAGRMSVNKDTNKIHVPKFKVDARFTYFMNGEFKTE
LLETVRGKDVYIFQDVENKQEITINEGKNKEVFSVNDHLMSLIVTIDAVR
HAGAGRISLVLPVYPYSRQHKKKGREGLTASLLGHIYEDLDVEQIITLDI
HSREIENSFHSARLQNLHASYQIIRELTRILDLSADSEEQFVVVSPDSGA
VDRNKFYSSGLQKPLAMIYKERDYSVVTQNAKQSNIISIKLLGDVEGKNA
FIADDMLGTGGTLLKAMEFLKSKGAKKVIAAVSLPFFTGDAIQQFDEAYS
KGLFYRVIGTNAVYHTELKQKEWYIETDVSGLFAQVITRLHENLSLSSLL
DNRDIIEKLLKNAAIPKK
>TDE0686 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MISRNAAFRESNLPLPSKQTGKVRDWYSPEEGKRLIVTTDRISAFDRVLT
ALPYKGQVLNQLSLWWFENTKDIIKNHIISCPDPNCIIVTEVKPLPIEVI
VRGYITGVTSTALWYRYSLGERNIYGYDFPEGLKKNQALPKPIITPTTKG
GPTGHDERLTCDEVVSQGYLSKEQWDFVQKAALALFERGQKSAKEAGLIL
VDTKYEFGVDKNNNILLIDEVHTPDSSRYWKLDTYEQRLKEGKEPENFDK
EFVRMAYAAKGYRGDGEIPELDENVWNEAIQLYITAYEKLTKSKFVPGEY
PAEERIVKNLKKAGLM
>TDE1267 purD, phosphoribosylamine--glycine ligase
MNILLVGSGGREHAIALKLKESPSLGKLFIAPGNGGTALLGENVPIKADN
IEGLADFALSASIDLVIAGPEVPLCLGFEDLIKEKAKAQNKKIAFFGPSK
ACARLEASKDFSKEMMSLLSIPTARYSSFTDFQKAKKYIEGLDYPFVIKA
DGLAAGKGVILPDSKEEGIAELKNIMIEKQFGTSGDKVVIEERLEGEEVS
ILAFSDGEKIAVMPPSQDHKRLKDNDEGPNTGGMGAYAPTPICSYEEAEK
YAALTILPIVKEMKKRGTPYIGVLYAGIMLTKDGKGFTPKVLEYNCRFGD
PETQVLMQLFDGDLALTMSYCAEGRLGEAMPKWKKGYAATVVLASEGYPL
SSSKPVELSASELEGSAEVSVIHAGTALKDSKIFASGGRVLCISSNDKSL
QKAMDNIYEKIKTIHFPGVQYRKDIAKRGLEHLNQLK
>TDE2407 purF, amidophosphoribosyltransferase
MSKDDIFKSSLGEECGIAAVWDSNSYKTENPERLPFRPDDAARSVFYALF
SLQHRGQEAAGMAVSNGKHIRVFKKPGLVSNIFTEHDISNLQGYAAIGHT
RYSTTGSSSFGNIQPFYIETMYGPIALAHNGNLVNAPHLRQKLLERGVGL
SSTSDTEVMIMMLAAAKGDSWAERIASCMREWEGAFSIAVLTVEGIYIAR
DPWGFRPLCVGSFQEGVSVAASESCALLTLGCRDVTEVKAGEILKLVDNG
AELCMRIPPKEPLSPCIFEYVYFARPDSVWNNASVHVSRVNFGKELAKSS
PVEADIVIAIPDSSRSAAIGYSQESGIPYDEGFSKNRYIGRTFIQPTQKL
RDQGVAMKFNVLSEAVEGKRIVVVDDSIVRGSTMGPLIKMLRGAGAKEVH
IRISSPPVRYSCFMGVDMGDPENLIAHKKSVEEIREHIGADSLVYLSQES
MLKAMKDAGANTHFCCACFDGKYPVDVSGAADKNSFE
>TDE1896 purH, phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
MGLVLASVSDKTGLKDFAFRLKAAGYDFIASGGTAKTLQEAGIKVKEVSE
YTSSPEILGGRVKTLHPMIHGGILARDTKEDRAELKALGFSGIDIVIANL
YPFEKTISSPDSTESDCIENIDIGGVALLRAAAKNYSRVTVICDPADYDE
VSSEIEKTGEISLSLRKRLAIKAFDLCTRYDAAITSWLSGLSRLSGGIEE
KTSLTLCAYPGQDLRYGENPHQKAWLYTNEPKAGPLGGKVLQGKALSYNN
ILDADAAWRAVSMFTKPAAVVVKHLTPCGLAEINEEPAKSSSSSLPNSEV
SLALRAAIDCDPVSAFGSIIALNRPFDKASVEALGALFVECIIAPLFTEE
AKELLSGKKNLRLIEAPILQEKEPYEYKSVLGGFLKQEKDLGDPEGTEYK
DAAERKAEPFERALLQFAMKACTMVKSNAILLAAPIDLSNPQKGFCSVGI
GCGQPNRVDAARQAIERAGERVKNSVLASDAFFPFPDTIEEAAKAGIKAV
IQPGGSIRDYLSIEECNKHGMAMLITGVRHFKH
>TDE1279 purL, phosphoribosylformylglycinamidine synthase II
MNDEELLALSNERRAALDIYEMRAIREFYKTEKRPCTDAEFETIAQTWSE
HCVHKTFKAKIDIDGTSLTEEQKKAYPGLCVNSIIKTYIKKATDDIDAPW
VLSSFVDNAGIIEFDEKYEVSFKAETHNHPSAIEPFGGANTGVGGVIRDV
MGVSARPFAVTDVLCFGHPDTPAENVPKGTLHPKRIISGVIEGVKDYGNK
MGIPTVNGGVHYHEAYASNPLVYCGCAGIAPRGKHRTKPSAGDHIISLGG
KTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKKVAEVLIDARDQ
GLYSAITDCGAGGYSSAVGEMASALGCDVDLAKIPVKYQGLAPWELWLSE
AQERMVIAVPNDKLEALQKLCDANDVELTNLGRFTGDAVLRVRFGEKEII
NLSCGFLHSGPPQRKLKAAPPKDGKPFIKYPEYKEPDLNAALKAVINHHA
VNSKEDIVRLYDHEVQGGTVLRPYDGPEGNVPQDAAVIKPMETEGKKAVA
ISNALNPRQGLLDPYAAAASAIDEAVRNAVAAGADPEKTAILDNFCLGDP
NRPETMWALIEMARSCYNTALVFKTPFISGKDSFNNEYLSSEGKRVSIPP
SLLISAMGIVPDIGRVPGSDFKKEGSAIYLVGKPQFSFGGSVFAELFGIP
SGESAAVPPFKKEAAELYKKLHSNIMKGLVLSCHDLSEGGLAAALYEMCL
SGIGAELKEDFHTRLGASKIASLFGETTGCLLVEIKEENRSAFEKEMEGA
SIYEIGKTCGKAGLKL
>TDE1266 purM, phosphoribosylformylglycinamidine cyclo-ligase
MNEMKNKNQEQPKGKSEDLSKDKSSVYSASGVNIDAGNEAVRLMSAAVRS
TFNKSVLSDVGTFGGLFGTEELFKMKKPVLVGSTDGVGTKVKIAAEAGRY
TTIGQDIVNHCIDDILVQGAKPLFFLDYVASSKLDPQMIADIVGGMAKAC
KESGCALIGGETAEMPGVYMEGEFDIAGTIVGAVDEEKILPKKNIKEGDL
LIGLASDSPHTNGYSLIRTAFKGVDLNTVYPELKAPLHEVLLKPHRSYLN
AIYPTLQEHPEIVKALAHITGGGFIENIPRVIPAGLVIKVKKGSWPVPPL
YPLIQKLTGASGDEMYRVFNMGIGMIAVVSPDMAEKYRELVGEESWIIGK
LEKAGNQTQKAVTILE
>TDE1897 purN, phosphoribosylglycinamide formyltransferase
MKKKLAVLVSGNGSNLQAVIDGIKNGSIDYKIEAVVSNKKEAFALSRAER
EGIKTIYLPFKKGSSRNEYDALLAEKVKEFKPDYVLLLGWMRILTDSFIA
TFKDRLINLHPALPGTFPGTEAIERQYEAFMKGEISRCGIMTHFVPDEGV
DSGPVIFTEEVPVFQGDRLEDFEKRVHEAEHRLVIKTLKFLSKV
>TDE1405 purQ, phosphoribosylformylglycinamidine synthetase I
MKPRALVLHATGTNRDGDAARALELAGAEPEIVHINKLKAKEKNWKDYEI
LVIPGGFSYADALGAGKLFALDLSNYFFDEVSEFVAAGKPVIGICNGFQV
LVKSGILPGKEKDGKVILDKDGYKNRQATLTYNKQGRFECRFTTMIPQKS
NCIWTKDLKGNIHCPIAHGEGRFLTDSQKTLDDLFEKGQIALVYGGKDAE
KSIPANGEYPFNPNGSLADIAGICNTKGNVLGLMPHPENNVVIRERDSEE
EKERTKLCLDMWKAGVNYVL
>TDE0129 pyrBI, PyrBI protein
MENKFMGRSLTVIDDLSIDERKYLFDKTKRLKKAIQEDDQKVMDEFRIND
KDFGIYEVFLEPSTRTKESFRNAAKFHQVKLSDLAAESSSFNKGESYADT
FNTLAGYQNSIFIVRSKVEGVCRWLEDEAQAFYQRNNLKRKPAFINAGDG
KHEHPTQELLDEFTFIEDNNWSFDKIHIALVGDLYHGRTVHSKADGLKIF
KSVKVDLIAPAELAMPEYYKVRMQENGFTVREFSSIEEYLRQADVALIWY
FTRPQLERMGEQVLKKQDELRRSITFRKEFIEKLPENTRFYHPLPRHRVH
PTIPTFLDATPLNGWERQSINGMYVRMVLLSMIAGKIGDDYKGPEPKSCE
RVEDEDYIVEVPINNSKESKVETFSEGVRPIQNGIVIDHICRGDKPSVIR
HHMSKIINVMGLEEGKGGEWVSTSTKDKGTFKGIIFRPGEYKFSRADLKR
LSAVASSCTLNLIKDGKIQSKYRTHLPPRIYNFEDLICKNEACISHPAQS
EGVPAIFYRTIDNRYACQYCGTIHTFKEIWGEKKN
>TDE1001 pyrE, orotate phosphoribosyltransferase
MHKDEKKIAEVQKKYGALLAKTAFELGALKLSPNEPFTWASGYRMPIYND
NRRFLALPEMRRTIAEAFAELLKAVDFDPEWLAGTATAGIPHSVSLGDLL
QKSVSYVRSGGKDHGLKNQIEGLGANADYKGADVLVVEDLISTGGSSIKA
VEAVRNANGKVPFCFAIFSYGFAEAEKAFAELKPSCIPVTILNYDIMLDE
AVKQNYISEENKKSLGEWRLDPFGWGEKHGFPKV
>TDE2110 pyrF, orotidine 5'-phosphate decarboxylase
MNYIDLLKTSAKKTNNCACMGLDPIFEAVPNKTGMVKDNLVSFFKELFNK
MQEKNLIPAAFKPNIGYYSALDKPREKDFSGSESLAEILSLIEKHFPGIP
VILDSKRGDIARSSLNYAIEAFDGWKADAVTVSPYMGSDSILPFISEKYL
DKGAYILNRTSNPGAKDFQNLKTDSEGKNNSELYIEVAKKIAFYAKEFPG
TGAVVGATGMEELKIISGIYAQAGEVPMLIPGVGSQGGDAKTVMEVLKNS
GCNLALIRINSSSALTHPWKKAPVPENYLELCINNIEKLLNETAINNISF
>TDE2692 pyrG, CTP synthase
MKSKFIFITGGVVSSLGKGLTAASIGMLLKSRGYSVVNQKFDPYLNVDPG
TMNPYQHGEVFVTEDGGETDLDLGHYERFTDVPLHKFNSTSAGKVYLAIL
DRERAGGYNGGTVQVVPHVTDEIQSRILGTAEQTGADFVISEIGGTVGDI
EALPFIEAIRQIRYTVGKENCMFVHLGLLPYLKECGEIKTKPMQHSVKEL
LSFGIQPDILICRSEKRLSKSTREKLSLFSNIPQDAIIENLTAKSIYEVP
LMLEEAGLGKVLCKLFNIENKEPNLEEWKKMVQTYYNPEKEITIALVGKY
VELPDAYLSVAEALTAAGIYHKTSIKLLWIDSKKIETKEDAAAFLKDADG
IIVPGGFGDRGINGMLLTAQFARENKIPYFGICLGMQISAIEYALNALHI
EEANSSEFDKNAKNPVIDLMPDQKDVKIGGTLRLGLYRCMIAEGSLAEKA
YKSHEIQERHRHRYEFNNLYREKFDNSDMIFSGLNPERNLVEIVELKSHP
WFVAVQFHPEFASRPNKPHPLFRDFIKAAVDNKINR
>TDE2599 tmk, thymidylate kinase
MILPNFVVFEGIDGSGTTSQIRLLKERFESEDKSSLVSFTQEPTSGPIGT
LIRSALQGSFKLAPETMTRLFAADRCEHIYGLQGILKQVNDGRAVFSDRY
VFSSLAYQTAAGAADLAKLQNDGFPLPEFLFFFDLPVDISMNRVMGRSNV
LEIYEEKTFQYKVQDEYKKIIDEYRLKEPNMNIVIINAVEQIEEIHEKLW
SILKDLPKI
>TDE2251 uraA, uracil permease
MSHKRIYQVDEKVPAGLFLPLSIQHTFAMFGASVLVPIIFGIDAGIVLFM
NGVGTLLFIAITKGKAPAYLGSSFAFLGPAGLIISSMGFQYAQGAFIVTG
LLGCLIAFIIYKFGTSWINVILPPAAMGAVVSLIGFELTGLTVRGGTIGA
NIMTESASRGDIIVFFITIGAAVLGSVLFKGFLSTISILIASIAGYIAAI
FFGMVDFSIIREAGLFTLPHFQLPKFDLMAVITMLPVLLVITSEHISHQV
VTSNIIGKDLLKNPGLHRSIFADNFSTALSGLVGGVPTTTYGENIGVMAV
TGIYSVYVIAGAAIISICMAFISPLAALIRTVPGNVIGGITFLLYGMIGA
SGIRLLVDSKVDYSKSKNLILTSIVFTTGLSGLSIKFGEIEFKGMVLASL
VAVALSLIFFIFEKLGVLEE