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# Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130

>LIC12614 conserved hypothetical protein
MNGIWDPKKLNVNCNGRDVSGMSQSDGFFKIEPVTKEYILSQVGIKGDWN
ISEIYDGRVKLSIALMGDSPENEFFFAMGEERLPCVFTIKDKSDGGMLGF
SAQGRVWERPNIEKGKEYKDKTWVFLLPDYKGVLTA
>LIC12313 HIT family hydrolase
MTDPNCIFCKIIRKEIPSKVVFENDEILAFYDISPQAPVHIVFIPKKHIP
SLSEIENEDSHLLGNILLQIRDTAKNLGFAENGYRVVNNTGKNGGQTVFH
IHFHLLAERRLHWPPG
>LIC13172 conserved hypothetical protein
MGKSNPSPRWEIFTSSYLQCFGKKISTETFFQDYQDPDSFRKFYQFNHRG
PFTEFQAKFNLIIALSKFDPAEISLVATRVVENQFLQGVTYGEYRLMYSP
LETEIGIYEKTLAACEGLALGEQKTGGLAKGKLVISLHRDGDVFQEYLIY
KNIMEKNSLIRNYLVGLDFCYIEEGFPPKGKRKFFQEVNRDNQAEKNTAL
AILYHVGESFQDKSILSASRWVLESAEWGAHRLGHAIALGLHPSEKMKDE
ITEPRSERLDQLQLYYDRKEELDSYFEVPSREKIGNEIDSLKHKETVKFN
ISPSFLEECIGFQNYCISKIKQTNAIIESCPSSNEYIGMVVNPESHPILR
FAKNDMKFTISTDDPGIFGTSIKEEFSKAAKIGLSTEVLETVRRNSFLFT
SEILSGKKSSSEFEVLESF
>LIC11581 conserved hypothetical protein
MGKVKFSERDLILFVDWKKMLPLILGIYFLYSSETMSEPNSFRWKDGEIV
VNGKAYNRQIYFRHKKLSHFANWENIEKLFLSPDKKSLVVYHRADKEKFY
RLTLFRFETRNHTLVRSIQPGMACHDLFWYRDKIIFKTGTTGGGTYLTYY
DKNLKKINEINSYHFYVDRSLGIALASPVYGPDDGKFWIYSLYSGKIIET
FDYKKEMNENYTITDLKKIGAHKFMIRISGYHTERTKTFIKNIPKMR
>LIC10549 xanthosine triphosphate pyrophosphatase
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKE
NALIKAKELFYLTKIPSIADDSGICVSALKDEPGVYSARFGGPELNDEGR
ALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGI
YGFGYDPIFIFPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP
>LIC11870 hydrolase
MCVMEDSNSTQWDEPRKNLFSIHKLDYARGKRPDVDCILCGICRKDPEVP
NLTVAETNFTIVSVNLYPYNPGHLIVFPKRHILSYEELTKEEAMEIHEGT
VKAISILKKLWNVQGFNLGYNLGKNSGGSIPHIHEHIVPRFPNEAGFLDV
LANSRIVIYEPYEMQKEWIRIWKEFS
>LIC12227 conserved hypothetical protein
MKKRIVSTVLGLAIFAGTSLISNRAEAKGYGEAGCGLGSILISSKGFVQI
FAATSNGTSGNQTFGITSGTSNCTADGIVKLEKAQEMFVTVNYESLEQEM
AIGKGEKLESFAKLLGCDAGSVSRFGKLTKEKYSSLIKQETTPSLLLSAV
KSEVKGDTSLSKNCTL
>LIC10257 MutT/nudix family protein
MKYCSSCGSSVTYKIPEGDNRSRHVCDQCGTIHYQNPKIIVGSIPIWENR
ILLCRRAIEPRKGFWTLPAGFLENRETVEEGAIRETKEEANAEINILGLQ
SVYSIPHISQIYMFFLANLVNGKFSVSSESEEIKLFSIEEIPWEELAFTS
VSFALRKYVDSSVKNSLHLGNTRDRKNLPKES
>LIC10270 chlorohydrolase family protein
MEYELVNACIVTKDRWISNGSIVIKDGIIASVNAGGPPAGKRIRLNLNGL
YVYPGLINGHDHLLSTYLPRVAPSKPYLNWLPWDNDLKSSIVFSERQQLD
PEQLYLLGSYKNLISGVTSVQDHIPHFVQDPFIETMPVRILNRFTLSHSI
CTYSLDWGDGPEEEYAKALKQDIPYITCIAEGFDSESRDSLKNLYQLGCL
GEHTVLVHGIVLSESDITLIAQKKSHLVWCPEANLFLYERTTDIKDVLKH
GVNVCLGTDSSICGSLNLLEEIKNARKFYQTEYGEDLSPKTLFEMVTSNP
AKAFRIEKQLGSIEVGKIADLTILTRNFEDPYLNLCESNLNSIRLVLRDG
LPVYGDISLKSFFEESGVRVEKISIENAEKYLVASPGKLLESLVVSLGYK
KDLAFFPVQKEFDNFE
>LIC11383 conserved hypothetical protein
MLLETCRGKSMELFAVFAINAVVSVVLYYTITSKVTERIRTHMLGKINEE
IRDFIDELETESLRQVDLMGARILTFKEITSKAEELVKRIEQSTSPDILE
KIQIVDKDSVINNENKRSENLYPLKNGNHTGVSDSVQQGVGHIYKENLDL
TREDAENFSNLQKVSNSKIHTSYIQKLETTSKVVKKEVVSQNKPEILPQG
STSNLVLETIGKGIRKFFGIQEIKTIRSENETSGNDFFPGTRNSTLDISL
DENPFAPISESKLNETSSLVFKDNLKPKEADFGRILQENIVGYQPIKPDS
TKISAEAALLEIGDDSTKIEKVVFLLKRKYTHEEISEVLDLALGEVDIIE
RFRLDRNRRF
>LIC12559 conserved hypothetical protein
MDILLLDDGQKIQSSLIEGSVGTDSLLVPGVYWNRLNLQEKKALRNKLPF
LLRKYSKQIASMKRLHNKAGKIKYNRGVGKMKKLSIRVHSGVWATLGVLA
AAHGVSRCYLFNYMLWLDEQGDFFVKTLNRGVPIFHWTYKMIWKIDRRQN
FISRELQFEPNPMTNQYPYYLKE
>LIC10680 conserved hypothetical protein
MYIAKIQVVLKESVLDPQGSTVKKVLSEVGEKSVQDVRVGKYIELKIDAP
SEEVARKDVERLCDKILVNHIIETYSMNIQKI
>LIC10196 conserved hypothetical protein
MIFISVALFAEAKPLIENLGLNILRNKTVFPIYQNENHALVISGTGKIYS
AMSVVFLLNEFKDQISDSSWILNFGVCGARKDISEIGKSFLIHKITDEGS
FKNVYPDILFHSPIPESALRTFDKPIFDDVVSELPNTLVDMEAFGFFTAS
RKFFSSDKIRVVKIVSDNLNKLEYSKITNIPEMISFRIQNSLSDILSILS
IPVFQKNNIQLLAEETSTLLQICEVLRLSETERIQLKDWMIGYKMRTGNS
PDLGLSILKNSNGFLKPGQTKVKTRELGKKGLYALKQFYQS
>LIC11447 conserved hypothetical protein
MRKFNGTEFYSFLFKSGCTMIEKIIEDFKDSVKESVKSVRIPLEVHSKTG
NYSAEIGGWEGTSMSLNLERFNLDSVGEPATLEVKIPFWKDPILLHGTIT
EKKIVRSRSQDRMTDNVLLFESDAIGLVKKFLPKFPLDLKEWKLLEFSKK
AVLPSYFPKNLRMWELI
>LIC10601 conserved hypothetical protein
MSAKGISKDLIGTKLDHYEFDVERGKIREFCQAIGETNPIYFDVEAAKKA
GYEDTPAPPTYPTVIQFWGYPKIWQDMENMGVDTSRILHLKEKYTYLKPI
YPGRVSSQGECINVTVGKMDTMTFKTTIKNAKGETIVEQEMSIFIRKPEA
>LIC11945 GMP synthase
MRSLIVRFKDCEGPGILLNSLKKRNYKITYHNAYDLRVKPLPDAHLVFDL
IVLLGGPQSVTDHSLADFFEPWLNLVRYAKSIPNCKVIGICLGSQIISKA
LGGEVKRGENGPEVGFYDVQVQEPHFLFDGISSFPAFHLHEDVFSIPEGT
KRLLKSEKYSNQMFSFEDRIFGIQCHLEITASMLSIWQKAHSDFIRSAGW
IPGPETEFLRSQMEKVGGSIFEKILDHSTGFETNHRALLSSQAMTAKSG
>LIC10353 conserved hypothetical protein
MKIQWFHYENEGYYLSVKNLNEPIESLNPLYLRITHFNQNIDKIIGFILD
RYLQYLDIGPLRECIFSILRETLMNAIKANQKRMVFKEAGLDIKDPDQYL
IGMERFKEELISKKDLYADLLEQNGLYVLITFGFNQNSFLLKVSNNVGIL
PEEDQRIQERISKARSYNDLSEVFENHGDESEGAGLGLAMSLLMLKNEGI
EGDSYRIKSEEGITSAYIKIPFEFKKRNINLQKTGDIFAELDTLPTFPDN
INQIMSLINKPDSSIQNITELVSRDVSLSTNILKLANSASFSQRARVEDL
EDAIKVIGLSELNNILLSLGTKKILEEKYNEFEAIWERSSLSAFICRRLG
ERMGWKKQTITVLVCAALLHDVGRVILLSIDPNVSAKISEILGNRLYPSP
LTLEEAALGISHTTLGGMICEKWNFSDTIRVAAEMHHRPLLVKREFQDTV
FAIYLSDMIIDISSGISDYSMIQSAVLQHFGFKKEEEFVEFMDKTLLEYK
NFP
>LIC10459 add, adenosine deaminase
MALTFQEILDRIRIIDRDVTELNRLKSRLPADRPYSSSLQISFDKQINEL
LNERVGLMELEVLDPPSWILGVPTTGISQETPVPLKGLFPSGDLSKEKPD
DQDVINFLRELPKTEIHLHLEACVNKDTMKRLMAKNGINVTDEEFEAKFN
FKDLNSFIQVFFFIQSLVKEPSDFSFFIESLAEYMRANNILYTEVFFAPS
KFIQNGLDFEEMIDFLVNRIREEKENDGIVIRLLVDVSRSFGPENAMKNL
DRVLKLRHPEVIGIGLGGAELMGPARDYQGVFQKAREAGLRVVAHSGEDD
GPWAIWEAVELLKAERIGHGTSAIQDPELVKYLRENHIPIEICVTSNVFT
GKYVRKEQNHPVRYYYDQGLPLSINTDDPEIFNVNLTYEYYKLWRFLDFS
LDEIVDLIRQGVFASFHPNKESLWAEMEKNIHLVKTRYGLKR
>LIC12852 adk, adenylate kinase
MKNIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEA
KRYMDAGDLVPDSVVIGIIKDRIREADCKNGFLLDGFPRTVEQAEALDTL
LKNEGKSIDKAINLQVPDAELLKRLLGRAEIEGRADDNEVTIKNRLDNYN
KKTLPLLDFYATRKKLSQVNGVGSLEEVTSLIQKELA
>LIC20142 apt, adenine phosphoribosyltransferase
MSIVKSKIRTIPDYPKPGILFRDITSLLLDPEGLALTIGTFVNRYQGKGI
TKVAGIEARGFLTGAPLAFQLGVGFIPIRKKGKLPSETVSEEYDLEYGKD
VIEVHKDSIQPGDKILLMDDLIATGGTMIAAVKLLKKLGAEIYEAGVIID
LPDLGGRKKLQEELKVPVFSICEFEGH
>LIC12466 carA, carbamoyl-phosphate synthase small chain
MMKAFLVLDNGTIFEGESFGYETESVGEIVFNTSMAGYQEILTDPSYCNQ
IITLTYPMIGNYGIHPDNMESSKIQASGLIVKEYVDLPSNFKSEKTLSQF
LKEYKIPAIQGIDTRKLTRFIRTNGSPNGGIFVASEYSPSFLEKVKSFPG
IINADLAEVVTTSSKYIFGTHTGKKFKLAVYDYGVKTNILRLLDANGFAV
TVYPAKTPSEEIMKEGTDAFFLSNGPGDPAPLDYAIASTQKIMEKRYPLF
GICLGHQIIGLSLGKKTEKMKFGHRGGNQPVKNLETGQVEITSQNHGFAV
IDDQKQDEPISFLNLNDHTVEGILKSGYPLLTVQYHPESAPGPNDSRYLF
QKFYDLVEKTKKG
>LIC12883 carB, carbamoyl-phosphate synthase large chain
MPRREDIRSVLILGSGPIVIGQACEFDYSGTQAAKALKEKGIRVILLNSN
PATIMTDPDLADATYVEPMTVPVVQKILEKEKPDAILPTVGGQTALNLAL
ACNSAGILEKYNVELIGAKVDAIKKAEDRELFKKAMEKIGVRVPASGLAN
NLKDAVEIKNKLGLPLIVRPAFTLGGTGGGIAYTEETFEEVVSKGLKASP
ISQVLLEESVLGWKEFELEVMRDLADNVVIICSIENIDPMGVHTGDSITV
APQQTLSDKEYQNLRDMSIAIIREIGVETGGSNIQFAVNPTNGDVIVIEM
NPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIKNDITRVTPASFEPS
IDYVVTKVPRFAFEKFPGTDDTLGVQMKAVGEAMAIGRTFKESFQKALRS
LEIDRYGFGSDGYFQELLYSRSLNNDQRKEWIDSHLKRPNDKRIFYVKLA
FDEGYTVDQIHDLCKIDRWFLWQMEGLLKLEKEYSEKGNSILYKMKQVGF
SNRQLSFLKNKKQILDLLDGNLRVDLKKTEIQNLLKLSEEEIEVELGSKK
ILPVYKRIDTCAGEFEAYTPYFYSSYDEEDESDVTNAKSVMILGGGPNRI
GQGIEFDYCCCQASYALQDLGIESIMINSNPETVSTDYDTSDRLYFEPLT
LEDVYRIYQNEKPEGVIIQFGGQTPLKLAKDLEKKGVKILGTSPDSIDRA
EDRKRFVEVLEKLKLNSPESGIATSMEEAREIAHKIGYPVLVRPSYVLGG
RAMLIINEEKELDRYMEKAEEISKDRPLLIDSFLEDAIEVDVDALCDGKE
VFVTGIMEHIEEAGIHSGDSACVLPPQTLSKNMMDEIRKATVNLALELQV
KGLINIQYAVKNEILYIIEVNPRASRTVPFVSKALGHPIVKYATRIMMGE
SLKSLPLPKEMEFSQVSVKEVVLPFNKFPGVDTILGPEMRSTGEVMGIAS
TAGEAFLKSQYMAGDELPSQGTVFVSINDKTKAELLSYIKDLSELGFNLI
ATSGTHKFLSDNGILSSKINKVYDGIFPTALDYIRENKIHLIINTPLSRV
TRDDSFTIRQAAIRFKVPCLTTSNAAKALIKGMVEMKNKGFTIHSLQEIH
AMPKIL
>LIC13472 cdd, cytidine deaminase
MSKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIR
TDNKILSDFLNKLENLVTRYREEIPSFTRIYHKEKLISETFNEVEKKSDS
SFHSEILCIRNAKEKLKTRYLADCMLITSLEPCLMCAGTILLSRIPKVVY
LLPAKQGEGISSLSIEMIYSRNFFPELFCIPTEISKNAFKSFFKVRRKKF
N
>LIC10065 dcd, deoxycytidine triphosphate deaminase
MILTGKEIQKRIGNDIVITPYSEKQLNPNSYNLRLHEELLVYTELPLDMK
KPNPAEKLVIPESGLLLKPGILYLGRTLESTETHNLVPMLEGRSSIGRLG
MLVHVTAGFGDVGFKGFWTLEISVIQPLIVYPGVEVCQIFYHTLEGQITE
YTSGKYQANRGIQTSMLYKDFEK
>LIC11663 dgt, deoxyguanosinetriphosphate triphosphohydrolase
MYFSRDDLLQKETETLAPYAISNANNGGRIYEEEEHSYRLPFQRDRDRIL
HSSAFKRLQYKTQVFIFSVGENYRNRMTHTLEVAGLSRTIASALGLNSLL
SESIALAHDLGHTPFGHAGQEILSGLMKDYGGFEHNKQSLRIVTSIEKKY
PNFPGLNLCRETLKGLMKHGADYDSSVILLERKENGPSLEGMIADLSDEI
AYTNHDIEDGWEMGYLHLGDLLENPFWKEVYEECKDQYKEVGEKILIRTS
IRTLTNFLVSDLIQNIAHRLEKKQIKSTEDLALLWKQDFRIASFSKEVDL
KFRELKSFLYEKLYRHEDLIRMSDYGKKIIESLFDYFLKHPEKIPDTYKE
RIEEESLYRVISDYVAGMTDRYAEKIYQSLP
>LIC12560 dut, deoxyuridine 5'triphosphate nucleotidohydrolase
MKIFVQKLRPNAELPLLQTKQAAGYDIHACLDSKLVLEPGNVGLVPTGLS
FAIPQEFHFEIRPRSGFSTKNRILIPNSPGTIDSDYRGELMIPLLNLGDS
SFIIEHGMRIAQLLIRKTWYADWELVSEFADRTERGANGFGSTGH
>LIC11831 guaA, guanine monophosphate synthase
MVIHKKIAVVDFGGQYAHLIASRIRRLGAYTEILSNEEPISNYQKYSGII
LSGGPESVYEPNSPTVTTRIFDLGIPILGICYGHQLIMKLLGGVVERSGT
GEYGPASLQLHGTNGNSILKNFVGGEQVWMNHADEVVKLPEGFSKIAFSK
DCGYAVVANSSKKIFGIQFHAEVSHSEKGSVLLDNFIQICGVSKTWGIDQ
FLKEKIKEIQETVKQEQKIFMLVSGGVDSTVSYLLLCKALGAERVLGFLI
DTGFMRKDEVVSLQKKLTFQNIHLTVRDESSLFYKSLKDKSDPEEKRKIV
GNLFLEARDRAVKDLDLEYGDWLLGQGTIYPDTIESGGTKHSHTIKTHHN
RVEAIQKLIEQGKVIEPIRDLYKDEVRDLGVLLGLESEWVGRHPFPGPGL
VVRMLAVEKKGTDKDQLEIDSYLSTQDGLSGKILPIASVGVKGDRRSYAN
CVVLNDIETDWNTLDRVATHLSNRFSFINRVVLLPFESDLKKWNFQFTGM
QLDKKCSDLLREADFTVESVIRKLGLYNKIWQMPVVLLPIGEKENEKSIV
LRPVESQEAMTANFFRMERSVLQEIKIEVLKIPEIRYLFFDLTNKPPGTI
EWE
>LIC13438 hpt, hypoxanthine-guanine-xanthinephosphoribosyltransferase
MKKINSDILHPRFSREDISQKVKSLALQISEDYKKLNPIFICVLKGGVYF
FTDLTREIPFSVEINFVQARSYSGTVSTGKIELLKDIDIDLSDRHVIIVE
DILDTGFTLQYLVRHIFTRNPASLEIVTLLLKERKDTLEFPVKYIGWRIP
DEFLVGYGLDFDGRYRNLPDIHVLEPGEPQFPV
>LIC13399 mtaP, 5'-methylthioadenosine phosphorylase
MSYNVRVAIIGGTGLYSLEGMELIEEIFPDTPWGKPSDKIKIGKYKGKLI
AFLPRHGIGHFLSPPEVPNHANICALKQLGVEEIVAFSSVGSLREEIKPL
DFVLPSQIIDRTRFRNSTYFGNGVVAHAPFAEPFSPNLSKRIAQTAKKIG
LEIHLDKTLVCMEGPLFSTKAESHLYRSWGADIINMTVLPEAKLAREAEI
AYQMICMSTDYDCWREGEESVTVEMVIANLTKNAETAKKLLSELIHVLGN
GDDLSLKNSTRYSIITAPEKRNPETVKKLRVLFPEYF
>LIC13326 ndk, nucleoside diphosphate kinase
MSRTFIMIKPDGVKNKHVGNILSRIEKEGFKILGLKYLKLSLEDAKQFYK
VHSARPFYNDLCNYMSSGPIVAAALERDNAVLHWREVIGATDPKEAAAGT
IRALYAESKEANAVHGSDSDDNAALEISFFFKGNELF
>LIC11587 nrdA, ribonucleotide reductase protein
MLWSKKKFMKMNRHFTVPQNGESSTIQWTKRNSKITNPDGSKVFEANDIL
VPEDWSQVAVDILAQKYFRRKGVPKYLKKVQEDGIPEWLQKSIPDTEKLE
SLKPEDRFGGETSALEVFHRLAGCWTYWGYKYKYFSDEESAKIFYDEIVY
MLATQMAAPNSPQWFNTGLNWAYGIDGKSQGHYYVDPSTGKLVKSTSAYE
HPQPHACFIQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRGEN
EPLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIEN
FIDWKVTEEKKVASLVTGSMLNNRHLNAIMSACYEMEGEDRFNPKKNSSL
KKTIQDAKKVLIPDNYIKRVIDLARQGYKEILFEELTTDWQSDAYNTVSG
QNSNNSIRLTNEFMAAVEQDQPWNLYFRTEKEKAKVEGRKAKPSQTLRAR
ELWEKISYAAWASADPGTQYHTTINEWHTCPEDGPINASNPCSEYMFLDN
TACNLASANLQKFVNLETLNFDVEGFRYLCKLWTIILEISVTMAQFPSKE
IAELSYKFRTLGLGYANLGSVLMVLGIPYDSQQAMAITGAISSIMHMTAY
ATSAEMAKEQGPFVGYAKNQKHMLRVIRNHRRAAYNAPSGDYEGLTITPI
GINPAFCPSYMLKAAQEDADLALSLGEKYGFRNAQVTVIAPTGTIGLVMD
CDTTGIEPDFALVKFKKLAGGGYFKIINQSVPYGLKKLGYSPSEIEAIVN
YCKGHATLNGAPVINTQALKEKGFTNEILEKVEASLPLAFDINFAFNKFN
LGENFLTKNLGISKEIFDSPGFSLLEHLGFTKEDINKANDYVCGTMTIEN
APFLKEKDYPVFDCANKCGKYGKRFLSYESHIRIMAAAQPFISGAISKTI
NLPEEAVIEDIKNAYFLSWKMMIKANALYRDGSKLSQPLNSVLELLNGIE
IDDQEEIREATISKDPVQIAEKIVTKYISHRRKLPSRRAGYTQKAIVGGH
KVYLRTGEYEDGQIGEIFIDMHKEGAAFRSLMNAFAISVSLGLQHGVPLE
EYVDAFTFFKFEPNGIVSGNKHIKMSTSVIDYIFRELAITYLGRYDLGQV
APEDLRGDEIGSKRATAESNGQEKETLSSMTAVIEPTPKKEVETISYSQM
ISKEKPSSSPSGISLLEEVKLAKIKGYTGDSCSECGSFEMVRNGSCLKCM
SCGSTTGCS
>LIC11257 ppx, exopolyphosphatase
MVQEKPLAAIDLGTNSFHMIIVRVRTNGTFEAIAREKESVRLGNRLQENG
PIDPESFRRGIDCLKRFKILAENAGAEIRAVATSALREASNQEDFLENAY
QEAGISIDVVSGYEEARLIYFGILQGIPVFDRKIMMIDIGGGSTEILVGH
RGNILFSKSFKLGAIRLSEKFFKEETLSNSDVRKCRLYIEEMLLPFRKIL
RDLKPDLVVGSSGTIQSIAGMILASRGETEEISLNNFSFTSSEFKKIRNL
ILEADTSKKRSKIPGLDSKRADIIVGGTLILEEIFDLANVSALTVSEFAL
REGIVYDTIRKWEHFENTEHSKHLDDIRQTAVHNFMKSFSRDEEFSKHVA
ELSLQIFDQLKSLHKLGQEQRELLEAASLLHEIGQSISHSAYHKHSYYMI
RNSEMLLGFTFLEIEIIALTARYHRKNTPKIKHREFNKLAEKNQTLVCQL
SAILRISSALNRNRGGLVSSVICKIEKNQIRFILESSKGYDPSLEIWAAE
EQKVAFEETFGYSVEFVTGT
>LIC10429 prs, phosphoribosyl pyrophosphate synthetase
MNGDIAVFAGNSNKQIAEEICTHLGIQSGKINLKKFSDGEISVKIEDNVR
GKEVFIVQSTSAPANDHLMELILIMDALRRASVSSISVVIPYYGYGRQDR
KVEPRVPISARVVADLIEVVGLDRILTMDLHADQIQGFFRVPVDNLHFAP
VLAEYVNTKKIDDLVIVSPDSGGAERARAFGKKVNGSLAIIDKRRPKANV
SEVMNVIGEIEGKNCILLDDMIDTAGTICKAADVLLKHGAKSVYCAATHG
VLSGEAVDRINSTQFSEVVLANTIAIPESKKINKLKSLSVAPLFANAIQR
IHTNQSVSTLFD
>LIC12565 purA, adenylosuccinate synthetase
MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKY
VFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECDRLQKEGFPVFDKLLLS
DACHLLFPYHSQIDSARETTLSQEHKIGTTKKGIGICYADKMMRTGLRVG
DLLDTSYQTRLKHLVDEKNRELDKLYGMPPVSYNDINEGLKFFLSKVKKN
IINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNPTTGGALI
GTGIPFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEKLRQKGGEFGAT
TGRPRRCGWFDVEMLKHSVRINGITSIALTKIDILSDYDTIPVATGYKLN
GKTLDCFPSQGLDKVEVIYEEFPGWKSDISGICEFQKLPEKCKNYISALE
KWIGVKINLVSTGPDRKDTIHGDSF
>LIC11016 purB, adenylosuccinate lyase
MIDRYSNPEISKIWELENKFEIWKEIEILACEIRMKRGEVPQEDFQEIKS
KAKFNVDEILEIESKVHHDVIAFLTNMNSYIGPAGRHVHYGLTSSDIGDT
ALCVQMVQAMDLILKKTDSLIEVVREKAIQYKNLPCIGRSHGIHAEPMTL
GLKFALFFEELNRNRKRMAEARNEIAVGKLSGAVGTYSNIDPEIETYVCE
KMGLRVDPIATQVVSRDRHAFYLSVLGVTASSLDRMATEIRLLQKTEGRE
VEEPFSAGQKGSSAMPHKRNPVICERISGLSRVIRANVNVGLQDVALWHE
RDISHSSAERVVLPDSTIALEYILDKMLFVIKNLHVYPDAIERTLGVTRG
LVFSQKVLLALIEKGKIIREEAYLIVQEHAMAVWASQSETLKSRLEKDDR
VSKVLTQKDLDDIFKIEPYLEKVGLIYKRLGLE
>LIC10679 purC, phosphoribosylaminoimidazole-succinocarboxamidesynthase
MNPSYKGKVRDIYDLGDKLILSSSDRISAFDVVFPQLVPDKGKVLNRISV
SWFEFFKDVPNHILETDVKYFPIPFQNHPDLEGRSVLVKKCKRIDYECVV
RGYISGSGWKEYKNDGTLAGIKLPSGFKESQKLPEPVFTPAVKNDQGHDE
NISEKEMENRIGKELFNILKEKSISIFLRASEVVDKAGIILCDTKFEFGI
LDGQVILIDELLTPDSSRYWSTDTYSVGISPPSLDKQILRNYLETTSWNK
MPPAPNLPAELIQELREKYQKIEDLILSCTSQKSK
>LIC10472 purD, phosphoribosylamine--glycine ligase
MQVKLKVLLIGSGGRESAIAFYLRKSVLLSELKVFPGNGGFPDQELLPPD
SFQVLDKNSVQSFLKQNPFDLIVVGPEDPLVAGFADWAAELNIPVFGPDS
FCAQVEGSKDFAKSLMTEAKIPTAEYKTFSEYSDSLKYLESKSIPIVIKA
DGLAAGKGVTVATSKEMAQTALKEIFKDKKFGSSGNQVVIEEFMEGQEAS
IFAISDGDSYFLLPAAQDHKRAFDGDQGPNTGGMGAYCPAPVISESILQK
VKEQIFDPMFDLFRKKGHPYRGLLYAGLMISPNGEPKVVEFNCRFGDPET
QCVLAMLDGDLLELLYRASTGKIKGIQAAVKKGAAVVVVLAAQGYPDFYE
KNIPLNLPETSGQNVHLFHAGTLKKDGKVFSSGGRILGIVAQGADLKSSV
DQAYSFLEKIQAPKTFYRKDIGYRAL
>LIC12292 purE, phosphoribosylaminoimidazole carboxylase catalytic subunit protein
MNTKVAIIMGSHSDWETMKEAEIILKEFGVSIHKEIVSAHRSPELMLEFS
KSAKEKGYSVIIAGAGGAAHLPGMVASMTTLPVLGVPIQSKTLNGLDSLL
SIVQMPGGVPVGTLAIGTAGAKNAGLLAVRILALQDPILSEKLERYRNQI
REDALSKNKDLL
>LIC13262 purF, glutamine phosphoribosylpyrophosphate amidotransferase
MSRIPDKSRIRRQAQDDKPKEECAIFGIFNSSEASNFTYLGLYSMQHRGQ
ESSGIVSSDGEHLYRYAGMGLVAHIFTETKLKELQGNAAIGHNRYSTTGA
SFLRNAQPLRVESHLGAVSLAHNGNLVNSWELRSQLEKEGSIFQTTIDSE
VIVHLMARSGETDFLSALSSALKKVRGAYSLVILTKTQLIAVRDPNGFRP
LVMGRREDGSIVFASETCAFDITDTKYERDVEPGEMIVVDKNGMNSYYPF
PKASPSLCIFEYIYFARPDSSIFGESVYKVRKNLGRFLARELPVPADVVI
PVPDSANIAALGYAEESGISYQSGLIRSHYIGRTFIEPDQKIRDFGAKIK
YNVVRNVVEGKRVIVVDDSIMRGTTSRKIIKMIRNAGAKEIHLRVSAPPT
ISPCYYGIDIPTHNELIAATHTIEEIRKYLRVDSIAYLSVESMNRAVMDH
KGGGFCNACFTAQYPVEFQSELGNQKSLFKEYQVEERVVY
>LIC11655 purH, PurH
MIQIKRALISVSDKSGLVEFAKFLNQNGVEIISTGGTLKLLKDNGIAAIA
IDDYTGFPEILDGRVKTLHPKVHGGLLGVISNPAHKQKMEELKIPKIDLV
VVNLYPFLKTVSKPEVQLEEAIENIDIGGPSMIRSAAKNYKHTLVLTDPN
DYKEIQNLISSSGISEEISASYMRKAFSHTAMYDAAISSWFYKQSGEVFP
DVLNLSFIKKQKLRYGENPHQAASFYEPLFTKSDFSPLQGKELSFNNMLD
FDAAFHISSLLPENTVCIIKHLNPCGIAYADNPLEAFQLARRTDPISAFG
GVIGIKGQVNGELATSITENFVEGVIAQKFTQEALEVFSKKPNIRLIEIQ
DFKEALDELDLRPIHHGLLIQDRDYTTITEKDLKVVTKKQPSPDDIRGLM
FAWSCVRFIKSNAIVYTEENATLGIGAGQMSRVDSVQLGANKALNVGLSV
VGSYVASDAFFPFRDGIDTLAKAGAKAIIQPGGSVRDEEVIQAADEHGLI
MVFTGMRHFRH
>LIC12293 purK, phosphoribosylaminoimidazole carboxylase atpase subunit protein
MNNSRMLLPGSRLGVMGSGQLARMFCLEAIPFGYEISVYSPEKNSPAAGA
GAKEYISTYEDEKALTFFLENIDGLTFEFENIPEIALTTIENFSKRTGLI
VRPSPNCVRISQNRWKEKTSFQKAGIPTVKFYPVLTEEDKKSVLSKTNFP
CILKTNTMGYDGRGQIRCITEQELSLVFSNLNKPDHIVEEFFQFTSEASV
IMARFEDGKILNFRPSKNVHKNHILDLTFYPGNFPDSIETKLVNYAKKLA
ETIDYVGVFGIEFFIRGDEILCNEFAPRPHNSGHFSQNSGTISQFSLQLR
TLCNLPSPKTILANPVSMKNILGEDYKPGSTLWNKTLENPYYHLHLYGKT
EIRNGRKMGHWNYSGPNIESAFLNWD
>LIC10681 purL, phosphoribosylformylglycinamidine synthase
MKIAVITFPGSNCDSDIYRVLKDQYNAEVDRIWHRDGLDKKYELVILPGG
FSYGDYLRSGAMAGFSPVMKSVKEHVDKGGKLFGICNGFQILTEAEYLPG
ALIRNKTLKYICKTVILTKGSAGNPVTASMDVRKELKIPIAHADGCYYAT
SDVLKQLEDEDRILFRYSGENPNGSLDSIAGITSKNFKIVGMMPHPERAM
NPITGEMDGKVVLDLILGS
>LIC11123 purM, phosphoribosylformylglycinamidine cyclo-ligase
MDTEKGREFIQKIKRNVESTHGPRVIGGLGGFAGAYDVSVLKKYKHPILL
SGTDGVGTKIELARLLKIYNTIGIDLVAMCVNDILVCGGEPFFFLDYIAC
GKLDPEKMDQIVSGIVQGCKMSNASLLGGETAEHPGTMKEDEFDLAGFVV
GAVEKDSMIDGSTIRSGDKILGLESSGPHSNGFSLIRKLLLKEGKYLPTD
PQQVKFLKDYALKPTRIYVSSILKLLQQVSVKGMVHITGGGYQENIPRIL
PQGTQSKFFKEKIPSGYFFEKIKKDHKIEELELFATFNMGIGYMVIVSEE
NAELAKKIMESSGEVVHEIGEIVSGNKEEVQFV
>LIC11656 purN, phosphoribosylglycinamide formyltransferase
MATLFTKPKKKIVFLASGRGSNLRAVLQNIKVGKIRGIAQILICDHPDAK
ALEVAQEFELTSQVLNFSSFSNKSEYHTKLLQLLLEIKPDLIVTAGYMRI
LKSPVIQTFSNRIINIHPSLLPAFPGLNAQKQALEYGVKIAGCTAHFVDE
GIDSGPIILQGVVKIEEGMTERDLTLEILKEEHKILPLAVQYFCEDRLTI
QNRKVKIG
>LIC12402 purQ, phosphoribosylformylglycinamide synthetase
MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSY
KNSILKLKTLPTTSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAV
EPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPKNKYLLSRAVK
GIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGVVRHDQMASATTGG
QVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLL
MEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRE
TGMNAYEAMLSESQERMLVVPKKGKESELVSIFEKWNLNAVKIGEVTADG
MIEIYMGGKLKAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIP
DVTKGANSKEILLKILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLS
AIPGTNKALATATDCNSRYTYLDPYKGAEFAVCEAARNVYVTGATPYGVT
NNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGP
IFPTPTIGMVGILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKI
HGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSLGGIAVALSKT
VLFSGLGIESDLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEA
YGLKFYPIGKTNSSGILEIKDAEIKISFQELSGPYEKGLEAVFAL
>LIC13413 purT, phosphoribosylglycinamide formyltransferase 2
MKKKILLLGSGELGKEFVIAAQRLGQYVIAVDSYDDAPAMQVAHEKEIIN
MLDGNLLDQIIAKHKPDLIVPEIEAIKTERFYEYEKQGYQVVPSAKAANF
TMNRKSIRDLAAKDLKLLTAKYAYASSIDELIKATEILGFPCVVKPLMSS
SGKGQSVIQSREEISKAWEASQTKGRAGAAEIIVEEFIPFESEITLLTVT
QKNGKTLFCPPIGHRQERGDYQESWQPAAISEVQLKEAQRMADAVTKELT
GFGIWGVEFFLTEDKVYFSELSPRPHDTGMVTLAGTQNFNEFELHLRAIL
GIPILEITLERKGASAVILASTENKTPEISGLDIASGMSESDFRIFGKPI
TRPYRRMGVTLSYSTKGEEISSLRKRAVLLASKIKVD
>LIC12839 pyrB, aspartate carbamoyltransferase
MSKGSFFTFCRLMYYNHKNVLDTEQFSKPDLDFLIGKIRVMERLVEQNKA
FGILTGKLLASLFFEASTRTRLSFEAAMERLGGRVISTVGFQFSSISKGE
TLYDTMKMVEAYADIAVIRHPVEGSSRIAAGAVKIPVINAGDGAGQHPTQ
AILDLYTIISEKGTLDGLKVAFIGDLKYGRTIHSLINLLRHYKVRLFLIS
PPELALPESYKKALQGYSLTLEETTDIKAVWDCDVAYVTRIQEERFPDHK
EYERLKDLFKINKELILASKKETTVLHPLPRVNELSTDVDDLPNAAYFRQ
ARYGVVSRMTLLCLSLGQDF
>LIC10574 pyrC, dihydroorotase
MIKKISGRIVTHEKDFLGTVEWDSKTGLILTVLEQKESIPILNSQHQENE
IQFNSLETVIFPGFGDIHIHAREDESGKHTYKEDFVSASAAAVNGGVIHV
ADMPNNPIPPIDENSYSKKRKLADRSNIHITLYAGIGPDTKPLKKSVPYK
VFMGPSIGELFFHNNQTLEDTISSYVGENVSFHCEDPEILEKHQNETFHE
DRRPAEAETTATDFALYLIEKYNLRGKLCHYSTGEGLNKIKFAKQKGVKV
TCEVTPTHLFFDRSMLTPENRHWFQMNPPLRSKEDRERMLEGVKQGWIDY
LATDHAPHSIEEKRKGTSGISQLDTYSLFVTWLVLKAGVELKTVARICAK
NPGDFVNEYLPEKFGKGFGRIEPGYSANFTVLNLKKPKKFLKEEIKSKSG
WSPFENFEFPGSIEAVFFLGKQMK
>LIC13433 pyrD, dihydroorotate dehydrogenase
MINRNKIVLEMFLPHLRQSAYSVFLKPFFLSLDPETAHELAKNFLGIGQK
FPGFLTLMESMTSYQSDRLKTKIAGIEFENPLGMGAGFDKTGELYPFLSR
MGFGHIEVGTITGQKQSGNPKPRVFRYPQDQALVNRMGFNNPGADSAKKI
ISSQKKTKIRGINAGKTKIVPEEKAVEDYVYTLKKLSPYADYAVINISSP
NTPGLRNFQKQENFVSLIQGIRKDLGKNFKIPLFVKFAPDMETKELEALL
ETSLSLKINGVVLTNTTIDKSCLKNYPNVEKEGGLSGTPLKNRSTEFVRI
AYRILKRRIPIIGVGGIDSEKTALEKILAGADLIQIYTGYIYQGPFLPMR
ILKFLDRFLEKQDLKTVSDLVGKEKEIRLDQK
>LIC11076 pyrE, uridine 5-monophosphate synthase
MLKKELSMKQELLELIRTHVYRYSEQPFTLASGRKSRHYFNCKEITLVPD
RLELLCKFIVEQHLGESGILLPHAFGGLTMGADPICYGISLEFRKQNKNV
YPLIVRKLSKDHGTKKLVEGSAHLVKQCVVIDDVITTGGSTIQAIRSLRD
CGIEVVQGVCILDRQEGGKDAILAEGVEMFPIFKKSDFGNLEHE
>LIC11540 pyrG, ctp synthase
MEYTLSRTKFIFVTGGVSSSLGKGVTVAALGCLLESRGYTVSLQKMDPYI
NIDPGTMSPYQHGEVYVTADGAETDLDLGYYERFTHSKLTRKNSVSTGQI
YNTVIQRERKGDYLGRTVQVVPHITNEIRNRMYIVAREENPDFIIVEIGG
TVGDIESIPFLEAIRQMRYEHGSSNVLFVHLTLVPTITAAGEAKTKPTQH
SVKELLGLGIQPDILVCRVSQPMTKEMKNKLSLFCNVKEENVISASDIST
SIYEIPKMYKEEKLDEVVLKTMGMELRESNFSEWDKMVKGLLTTKQTVQI
AVVGKYISLQDAYRSIYESLSHGGIAHDTKVEFIKVDPENLNKDSYVEIL
KKVHGILVPGGFGDRGIEGKILAIQYARTNGIPFLGICLGMQCAVVEYGR
NVLGLKDANSTEIRPDTEHPVISLLEEQNDIEQMGGTMRLGSYPCKVKEN
TLSYSEYKSILIHERHRHRFEFTNRYRKQYEENGMIIAGTSPDDNLVEIV
EIPKHNWFIGVQFHPEFQSKPTLPHPLFAGFIRASVKYSKKG
>LIC10852 pyrH, uridylate kinase
MATEAKYNRILIKLSGEALAGEGEFGIDTNKAHSLAEEIKEVHDLGVEIA
LVVGGGNIIRGTNLAKAGIDRATADYMGMLATIQNALALQDACEKKGLYT
RVQSAIEINSIAESYIRRRAVRHLEKRRIVIFAGGTGNPYFTTDTTASLR
AVEVGCDVILKATKVDGVYTADPKKDNGAKRYSQISFMESINRRLKVMDS
TALSLCMENNMSIIVFDIFKRGNLKDLVTGKNIGTLISNSEDIQIDGK
>LIC12232 thyX, thymidylate synthase
MITSEKSIEIRDKVAKSTKKAGHLTTRQHPQFIFTLDKVSRQFVWSFLHS
HPFYNSEQVSQRYVEVKKENYYIPPELDGKLLELYLDAVDFASQSYFSYT
EALHPFIQEEYFQIYKARANYPDKWQTPIKKKCLEVARYLLPLGTFTYLY
HSVNGLTLHRYYRLMNSYDVPNEQRAVITEMINQVRAIDPLYADEMDDPV
PLEETTEYRYFDSMFGNGKREFHPETASTFVKEFDLELGERYSKLVSHSS
NGPEILAQSVRSILGIPKSILNDQDAIDLVLNPAKNRHLTSTLNESSMSP
ITRALFNVQYSFQKRISHTADSQDQRHRMVPGGRPVLMSQYAGIPDYITP
FVVQKYPELKEKYDVVHREIFEKLNRFLEAGGSPEHGTYLLPNSFPIRFY
ESGDLLNLHHKWRSRTCYNAQEEIFQASVDELTDVMKVHPQIAKWIKAPC
WIRLQGEVKPYCPEGDHYCGTQVWKRELSEYSRVI
>LIC12814 tmk, thymidylate kinase
MKNKKPIFVVFEGIDGSGKSTLCKSLTEKLIELGIPSAAFTEPTNLETGK
YLRKFLRGEIELGKEEQIEAFLNDREESLKQNILPALNSDKNVLLDRYMY
STAAYQSGDDLSPEMILKKNLNRNFKIPDLLFYLDLSPSIALERLNRRKE
GKERFETLAQLEKIRSAYEKILPKDTIRIDGNKNQNQIVQECLEIFLTNI
KSKS